Birger Brodin Larsen

Birger Brodin Larsen

Professor


  1. Published

    Nitric oxide, KATP channels and endothelin-1 modulate brain pericyte function, vascular tone and neurovascular coupling

    Zambach, S. A., Cai, Changsi, Helms, H. C. C., Hald, B. O., Fordsmann, J. C., Nielsen, R. M., Lønstrup, Micael, Larsen, Birger Brodin & Lauritzen, Martin, 8 Jun 2020, bioRxiv, 43 p.

    Research output: Working paperPreprintResearch

  2. Published

    Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

    Zambach, S. A., Cai, Changsi, Helms, H. C. C., Hald, B. O., Dong, Y., Fordsmann, J. C., Nielsen, R. M., Hu, J., Lønstrup, Micael, Larsen, Birger Brodin & Lauritzen, Martin, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 26, e2023749118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells

    Yasmeen, S., Kaur, S., Mirza, A. H., Larsen, Birger Brodin, Pociot, Flemming & Kruuse, Christina Rostrup, Aug 2019, In: Molecular Neurobiology. 56, 8, p. 5304–5314

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    In Vitro Blood-Brain Barrier Models-An Overview of Established Models and New Microfluidic Approaches

    Wolff, A., Antfolk, M., Larsen, Birger Brodin & Tenje, M., 28 Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2727-2746 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Carbonic anhydrase imhibitors. Transepithelial transport of novel anticancer sulfonamide inhibitors of the cancer-associated isozyme CA IX is dependent on the p.gp efflux transporter

    Vullo, D., Steffansen, B., Larsen, Birger Brodin, Supuran, C. T., Scozzafava, A. & Nielsen, C. U., 2006, In: Bioorganic & Medicinal Chemistry Letters. 14, 7, p. 2418-2427

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Transendothelial electrical resistance measurement across the blood–brain barrier: A critical review of methods

    Vigh, J. P., Kincses, A., Ozgür, Burak, Walter, F. R., Santa-Maria, A. R., Valkai, S., Vastag, M., Neuhaus, W., Larsen, Birger Brodin, Dér, A. & Deli, M. A., 2021, In: Micromachines. 12, 6, 18 p., 685.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Sortilin regulates blood-brain barrier integrity

    Toth, A. E., Helms, H. C., Harazin, A., Johnsen, K. B., Goldeman, C., Burkhart, A., Thomsen, M. S., Kempen, P. J., Klepe, A., Lipka, D. V., Møller, P. L., Andresen, T. L., Nyegaard, M., Moos, T., Larsen, Birger Brodin & Nielsen, M. S., 2022, In: The FEBS Journal. 289, 4, p. 1062-1079

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Stroke and Drug Delivery--In Vitro Models of the Ischemic Blood-Brain Barrier

    Tornabene, E. & Larsen, Birger Brodin, Feb 2016, In: Journal of Pharmaceutical Sciences. 105, 2, p. 398-405 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Modeling the ischemic blood-brain barrier; the effects of oxygen-glucose deprivation (OGD) on endothelial cells in culture

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, H. S. & Larsen, Birger Brodin, 19 Jun 2016.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  10. Published

    Changes in barrier properties and protein expression levels of bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 27 Aug 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  11. Published

    Changes in protein expression levels, Claudin-5 localization and barrier function in bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 4 Jul 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  12. Published

    Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

    Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, H. S. & Larsen, Birger Brodin, 2016.

    Research output: Contribution to conferencePosterResearch

  14. Published

    The in vitro blood-brain barrier model under OGD condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  15. Published

    Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism

    Thomsen, A. E., Friedrichsen, G. M., Sørensen, A. H., Andersen, R., Nielsen, C. U., Larsen, Birger Brodin, Begtrup, M., Frøkjær, Sven & Steffansen, B., 2003, In: Journal of Controlled Release. 86, 2-3, p. 279-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Erratum: Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: Affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism (Journal of Controlled Release (2003) 86 (279-292) PII: S0168365902004133)

    Thomsen, A. E., Friedrichsen, G. M., Sørensen, A. H., Andersen, R., Nielsen, C. U., Larsen, Birger Brodin, Begtrup, M., Frøkjær, Sven & Steffansen, B., 7 Mar 2003, In: Journal of Controlled Release. 88, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification and Characterization of a Novel Nontranslated Sequence Variant of the Human Intestinal Di-/Tripeptide Transporter, hPEPT1

    Søndergaard, H. B., Nielsen, C. U. & Larsen, Birger Brodin, 31 Dec 2012, In: International Journal of Peptides. 2012, 2012, 7 p., 743472.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3

    Søndergaard, H. B., Larsen, Birger Brodin & Nielsen, C. U., 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 3, p. 611-622

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1

    Søndergaard, H. B., Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2008, In: European Journal of Pharmaceutical Sciences. 33, 4-5, p. 332-342

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Calu-3 cells grown under AIC and LCC conditions: implications for dipeptide uptake and transepithelial transport of substances

    Stentebjerg-Andersen, A., Notlevesen, I. V., Larsen, Birger Brodin & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 19-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation

    Steffansen, B., Larsen, Birger Brodin & Nielsen, C. U., 2010, Pharmaceutical Press. (ULLA Pharmacy Series).

    Research output: Book/ReportBookResearchpeer-review

  22. Published

    Membrane Transporters in ADME

    Steffansen, B., Nielsen, C. U. & Larsen, Birger Brodin, 2013, Transporters in drug development: discovery, optimization, clinical study and regulation. Steffansen, B. & Sugiyama, Y. (eds.). Springer Publishing Company, Vol. 7. p. 1-22 (AAPS Advances in the Pharmaceutical Sciences Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Acid/base properties, solubility and distribution of drug candidates

    Steffansen, B., Nielsen, C. U. & Larsen, Birger Brodin, 2010, Molecular Biopharmaceutics: Aspects of drug characterization drug delivery and dosage form evaluation. Pharmaceutical Press, p. 5-31

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Intestinal solute carriers: an overview of trends and strategies for improving oral drug absorption

    Steffansen, B., Nielsen, C. U., Larsen, Birger Brodin, Eriksson, A. H., Andersen, R. & Frøkjær, Sven, 2004, In: European Journal of Pharmaceutical Sciences. 21, 1, p. 3-16 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Mechanism of decomposition of drug candidates

    Steffansen, B., Nielsen, C. U. & Larsen, Birger Brodin, 2010, Molecular Biopharmaceutics: Aspects of drug characterization, drug delivery and dosage form evaluation. Pharmaceutical Press, p. 35-48 13 p. (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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