Birger Brodin Larsen
Professor
CNS Drug Delivery and Barrier Modelling
Universitetsparken 2
2100 København Ø
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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP
Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, N. & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants of the human dipeptide transporter PEPT1
Anderle, P., Nielsen, C. U., Pinsonneault, J., Krog, P. L., Larsen, Birger Brodin & Sadée, W., 1 Feb 2006, In: Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 636-646 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1
Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2006, In: European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In Vitro Membrane Permeation Studies and in Vivo Antinociception of Glycosylated Dmt(1)-DALDA Analogues
Ballet, S., Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C., Lesniak, A., Kleczkowska, P., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D. & Schiller, P. W., 10 Apr 2014, In: ACS Medicinal Chemistry Letters. 5, 4, p. 352-357 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent
Berthelsen, R., Nielsen, C. U. & Larsen, Birger Brodin, Jul 2013, In: Journal of Pharmacy and Pharmacology. 65, 7, p. 970-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IN VITRO MEMBRANE PERMEATION STUDIES AND IN VIVO ANTINOCICEPTION OF GLYCOSYLATED Dmt1-DALDA ANALOGUES
Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C. C., Lesniak, A., Klecskowska, P., Chung, N. N., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D., Schiller, P. W. & Ballet, S., 31 Aug 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media
Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2005, In: Molecular Pharmaceutics. 2, 2, p. 98-108 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2
Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 2004, In: American Journal of Physiology - Renal Physiology. 286, 2, p. 385-393Research output: Contribution to journal › Journal article › Research › peer-review
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In-depth evaluation of Gly-Sar transport parameters as a function of culture time in the Caco-2 cell model
Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 1 Jan 2004, In: European Journal of Pharmaceutical Sciences. 21, 1, p. 77-86 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Function and expression of the proton-coupled amino acid transporter Slc36a1 along the rat gastrointestinal tract: Implications for intestinal absorption of gaboxadol
Broberg, M. L., Holm, R. K., Tønsberg, H., Frølund, S. B., Ewon, K. B., Nielsen, A. L., Larsen, Birger Brodin, Jensen, A., Kall, M. A., Nielsen, C. U. & Christensen, K. V., 2012, In: British Journal of Pharmacology. 167, 3, p. 654-665Research output: Contribution to journal › Journal article › Research › peer-review
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mRNA expression and transport function of the proton-coupled amino acid transporter, PAT1, along the rat intestine
Broberg, M. L., Larsen, K. B., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2010.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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The human proton-coupled amino acid transporter (hPAT1) is a transport system for GABA-like drugs
Broberg, M. L., Frølund, Bente, Larsen, Birger Brodin & Nielsen, C. U., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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5-Hydroxy-L-tryptohan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination
Broberg, M. L., Holm, R., Jensen, K. G., Sveigaard, C., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: European Journal of Pharmaceutical Sciences. 39, 1-3, p. 68-75Research output: Contribution to journal › Journal article › Research › peer-review
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Gaboxadol bliver absorberet via en aminosyretransportør
Broberg, M. L., Holm, R., Jensen, K. G., Larsen, Birger Brodin & Nielsen, C. U., 2009, In: Lægemiddelforskning. p. 22-24Research output: Contribution to journal › Journal article › Communication
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mRNA expression and transport function of the proton-coupled amino acid transporter , PAT1, along the rat intestine
Broberg, M. L., Brandt Larsen, K., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., Mar 2010. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Transport of Gaboxadol via hPAT1 and rOAT1 in the absence and presence of 5-HTP
Broberg, M. L., Holm, R., Larsen, Birger Brodin, Jensen, K. G. & Nielsen, C. U., 29 Jul 2009. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Proton dependent transport of amino acids in Caco-2 cells
Broberg, M. L., Larsen, Birger Brodin & Nielsen, C. U., 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Intracellular calcium modulates basolateral K(+)-permeability in frog skin epithelium
Larsen, Birger Brodin, Rytved, K. A. & Nielsen, Rasmus, 1994, In: Pflügers Archiv - European Journal of Physiology. 426, 1-2, p. 171-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An increase in [Ca2+]i activates basolateral chloride channels and inhibits apical sodium channels in frog skin epithelium
Larsen, Birger Brodin, Rytved, K. A. & Nielsen, Rasmus, 1996, In: Pflügers Archiv - European Journal of Physiology. 433, 1-2, p. 16-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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iP-gp , a novel cell line with tight barrier function and expression of human P-glycoprotein (ABCB1) for drug screening
Larsen, Birger Brodin, Ozgür, Burak & Saaby, Lasse, 23 May 2017.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Passive diffusion of drug substances: the concepts of flux and permeability
Larsen, Birger Brodin, Steffansen, B. & Nielsen, C. U., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Steffansen, B., Brodin, B. & Nielsen, C. U. (eds.). PharmaPress Ltd., p. 135-151 16 p. (ULLA Pharmacy Series).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Phorbol Ester-Induced Metamorphosis in the Parasitic Barnacle, Loxothylacus Panopaei
Larsen, Birger Brodin, 1997, In: Journal of the Marine Biological Association of the United Kingdom. p. 261-264Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for P2Y-type ATP receptors on the serosal membrane of frog skin epithelium
Larsen, Birger Brodin & Nielsen, R., 1 Jan 2000, In: Pflugers Archiv European Journal of Physiology. 439, 3, p. 234-239 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epidermal growth factor and insulin short-term increase hPEPT1-mediated glycylsarcosine uptake in Caco-2 cells
Larsen, Birger Brodin, Amstrup, J., Nielsen, C. U., Steffansen, B. & Frøkjær, S., 2003, In: Acta Physiol. Scandinavia. 178, p. 139-148Research output: Contribution to journal › Journal article › Research › peer-review
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Proton-coupled basolateral dipeptide transport in a human intestinal cell line, Caco-2
Larsen, Birger Brodin, Nielsen, M. J. & Nielsen, C. U., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
ID: 1299175
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition
Research output: Contribution to conference › Poster › Research
Published