Birger Brodin Larsen

Birger Brodin Larsen

Professor


  1. Published

    The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

    Ambjørner, Sophie Emilie Blomgren, Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, Nils & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Genetic variants of the human dipeptide transporter PEPT1

    Anderle, P., Nielsen, C. U., Pinsonneault, J., Krog, P. L., Larsen, Birger Brodin & Sadée, W., 1 Feb 2006, In: Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 636-646 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1

    Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2006, In: European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    In Vitro Membrane Permeation Studies and in Vivo Antinociception of Glycosylated Dmt(1)-DALDA Analogues

    Ballet, S., Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C., Lesniak, A., Kleczkowska, P., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D. & Schiller, P. W., 10 Apr 2014, In: ACS Medicinal Chemistry Letters. 5, 4, p. 352-357 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent

    Berthelsen, Ragna, Nielsen, C. U. & Larsen, Birger Brodin, Jul 2013, In: Journal of Pharmacy and Pharmacology. 65, 7, p. 970-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    IN VITRO MEMBRANE PERMEATION STUDIES AND IN VIVO ANTINOCICEPTION OF GLYCOSYLATED Dmt1-DALDA ANALOGUES

    Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C. C., Lesniak, A., Klecskowska, P., Chung, N. N., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D., Schiller, P. W. & Ballet, S., 31 Aug 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  7. Published

    Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media

    Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2005, In: Molecular Pharmaceutics. 2, 2, p. 98-108 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2

    Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 2004, In: American Journal of Physiology - Renal Physiology. 286, 2, p. 385-393

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In-depth evaluation of Gly-Sar transport parameters as a function of culture time in the Caco-2 cell model

    Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 1 Jan 2004, In: European Journal of Pharmaceutical Sciences. 21, 1, p. 77-86 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Function and expression of the proton-coupled amino acid transporter Slc36a1 along the rat gastrointestinal tract: Implications for intestinal absorption of gaboxadol

    Broberg, M. L., Holm, R. K., Tønsberg, H., Frølund, S. B., Ewon, K. B., Nielsen, A. L., Larsen, Birger Brodin, Jensen, A., Kall, M. A., Nielsen, C. U. & Christensen, K. V., 2012, In: British Journal of Pharmacology. 167, 3, p. 654-665

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    mRNA expression and transport function of the proton-coupled amino acid transporter, PAT1, along the rat intestine

    Broberg, M. L., Larsen, K. B., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2010.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  12. Published

    The human proton-coupled amino acid transporter (hPAT1) is a transport system for GABA-like drugs

    Broberg, M. L., Frølund, Bente, Larsen, Birger Brodin & Nielsen, C. U., 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  13. Published

    5-Hydroxy-L-tryptohan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

    Broberg, M. L., Holm, R., Jensen, K. G., Sveigaard, C., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: European Journal of Pharmaceutical Sciences. 39, 1-3, p. 68-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gaboxadol bliver absorberet via en aminosyretransportør

    Broberg, M. L., Holm, R., Jensen, K. G., Larsen, Birger Brodin & Nielsen, C. U., 2009, In: Lægemiddelforskning. p. 22-24

    Research output: Contribution to journalJournal articleCommunication

  15. Published

    mRNA expression and transport function of the proton-coupled amino acid transporter , PAT1, along the rat intestine

    Broberg, M. L., Brandt Larsen, K., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., Mar 2010. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Transport of Gaboxadol via hPAT1 and rOAT1 in the absence and presence of 5-HTP

    Broberg, M. L., Holm, R., Larsen, Birger Brodin, Jensen, K. G. & Nielsen, C. U., 29 Jul 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  17. Published

    Proton dependent transport of amino acids in Caco-2 cells

    Broberg, M. L., Larsen, Birger Brodin & Nielsen, C. U., 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. Published

    Intracellular calcium modulates basolateral K(+)-permeability in frog skin epithelium

    Larsen, Birger Brodin, Rytved, K. A. & Nielsen, Rasmus, 1994, In: Pflügers Archiv - European Journal of Physiology. 426, 1-2, p. 171-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An increase in [Ca2+]i activates basolateral chloride channels and inhibits apical sodium channels in frog skin epithelium

    Larsen, Birger Brodin, Rytved, K. A. & Nielsen, Rasmus, 1996, In: Pflügers Archiv - European Journal of Physiology. 433, 1-2, p. 16-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    iP-gp , a novel cell line with tight barrier function and expression of human P-glycoprotein (ABCB1) for drug screening

    Larsen, Birger Brodin, Ozgür, Burak & Saaby, L., 23 May 2017.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    Passive diffusion of drug substances: the concepts of flux and permeability

    Larsen, Birger Brodin, Steffansen, B. & Nielsen, C. U., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Steffansen, B., Brodin, B. & Nielsen, C. U. (eds.). PharmaPress Ltd., p. 135-151 16 p. (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Phorbol Ester-Induced Metamorphosis in the Parasitic Barnacle, Loxothylacus Panopaei

    Larsen, Birger Brodin, 1997, In: Journal of the Marine Biological Association of the United Kingdom. p. 261-264

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Evidence for P2Y-type ATP receptors on the serosal membrane of frog skin epithelium

    Larsen, Birger Brodin & Nielsen, R., 1 Jan 2000, In: Pflugers Archiv European Journal of Physiology. 439, 3, p. 234-239 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Epidermal growth factor and insulin short-term increase hPEPT1-mediated glycylsarcosine uptake in Caco-2 cells

    Larsen, Birger Brodin, Amstrup, J., Nielsen, C. U., Steffansen, B. & Frøkjær, S., 2003, In: Acta Physiol. Scandinavia. 178, p. 139-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Proton-coupled basolateral dipeptide transport in a human intestinal cell line, Caco-2

    Larsen, Birger Brodin, Nielsen, M. J. & Nielsen, C. U., 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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