Anette Müllertz

Anette Müllertz

Professor


  1. 2019
  2. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends. / Berthelsen, Ragna; Klitgaard, Mette; Rades, Thomas; Müllertz, Anette.

    In: Advanced Drug Delivery Reviews, Vol. 142, 29.06.2019, p. 35-49.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects. / Bergstrom, Christel A. S.; Box, Karl; Holm, Rene; Matthews, Wayne; McAllister, Mark; Mullertz, Anette; Rades, Thomas; Schaefer, Kerstin J.; Teleki, Alexandra.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 139, 06.2019, p. 101-114.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats. / Liu, Jingying; Werner, Ulrich; Funke, Mario; Besenius, Melissa; Saaby, Lasse; Fano, Mathias; Mu, Huiling; Mullertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 560, 05.04.2019, p. 377-384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration. / Butler, James; Hens, Bart; Vertzoni, Maria; Brouwers, Joachim; Berben, Philippe; Dressman, Jennifer; Andreas, Cord J.; Schaefer, Kerstin Julia; Mann, James; McAllister, Mark; Jamei, Masoud; Kostewicz, Edmund; Kesisoglou, Filippos; Langguth, Peter; Minekus, Mans; Mullertz, Anette; Schilderink, Ronald; Koziolek, Mirko; Jedamzik, Philipp; Weitschies, Werner; Reppas, Christos; Augustijns, Patrick.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 136, 03.2019, p. 70-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement. / Rune Jørgensen, Jacob; Leth Jepsen, Morten; Hagner Nielsen, Line; Dufva, Martin; Mørck Nielsen, Hanne; Rades, Thomas; Boisen, Anja; Müllertz, Anette.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 143, 2019, p. 98-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Polymeric Lids for Microcontainers for Oral Protein Delivery. / Mazzoni, Chiara; Jacobsen, Rasmus Due; Mortensen, Jacob; Jørgensen, Jacob Rune; Vaut, Lukas; Jacobsen, Jette; Gundlach, Carsten; Müllertz, Anette; Nielsen, Line Hagner; Boisen, Anja.

    In: Macromolecular Bioscience, Vol. 19, No. 5, 1900004, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Published

    In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp). / Khumpirapang, Nattakanwadee; Chaichit, Siripat; Jiranusornkul, Supat; Pikulkaew, Surachai; Müllertz, Anette; Okonogi, Siriporn.

    In: Aquaculture, Vol. 496, 01.11.2018, p. 176-184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers. / Blaabjerg, Lasse Ingerslev; Grohganz, Holger; Lindenberg, Eleanor; Löbmann, Korbinian; Mullertz, Anette ; Rades, Thomas.

    In: Pharmaceutics, Vol. 10, No. 4, 164, 21.09.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions. / Duraipandian, S.; Knopp, M. M.; Pollard, M. R.; Kerdoncuff, H.; Petersen, J. C.; Mullertz, A.

    In: Analytical Methods, Vol. 10, No. 29, 07.08.2018, p. 3589-3593.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine. / Ueda, Hiroshi; Wu, Wenqi; Lobmann, Korbinian; Grohganz, Holger; Mullertz, Anette; Rades, Thomas.

    In: Molecular Pharmaceutics, Vol. 15, No. 5, 05.2018, p. 2036-2044.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens. / Jorgensen, Scheyla Daniela Siqueira; Al Sawaf, Malak; Graeser, Kirsten; Mu, Huiling; Muellertz, Anette; Rades, Thomas.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 124, 03.2018, p. 116-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments. / Madsen, Cecilie Maria; Feng, Kung-I; Leithead, Andrew; Canfield, Nicole; Jørgensen, Søren Astrup; Müllertz, Anette; Rades, Thomas.

    In: European Journal of Pharmaceutical Sciences, Vol. 111, 01.2018, p. 311-319.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems. / Tran, Thuy; Chakraborty, Anjan; Xi, Xi; Bohets, Hugo; Cornett, Claus; Tsinman, Konstantin; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 107, No. 1, 01.2018, p. 103-112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin? / Vu, Hanh T.H.; Hook, Sarah M.; Siqueira, Scheyla D.; Müllertz, Anette; Rades, Thomas; McDowell, Arlene.

    In: International Journal of Pharmaceutics, Vol. 548, No. 1, 2018, p. 82-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus. / Johansson, Kristoffer Enøe; Plum, Jakob; Mosleh, Majid; Madsen, Cecilie Maria; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 107, No. 4, 2018, p. 1095-1103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems. / Kheawfu, Kantaporn; Pikulkaew, Surachai; Rades, Thomas; Müllertz, Anette; Okonogi, Siriporn.

    In: Journal of Drug Delivery Science and Technology, Vol. 46, 2018, p. 330-338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design. / Tran, Thuy; Rades, Thomas; Müllertz, Anette.

    In: Asian Journal of Pharmaceutical Sciences, Vol. 13, 2018, p. 536-545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility. / López-Barón , Nataly; Sagnelli, Domenico; Blennow, Andreas; Holse, Mette; Gao, Jun; Saaby, Lasse; Müllertz, Anette; Jespersen, Birthe P Møller; Vasanthan, Thava.

    In: Food Hydrocolloids, Vol. 79, 2018, p. 117-126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2017
  22. Published

    From concept to in vivo testing : Microcontainers for oral drug delivery. / Mazzoni, Chiara; Tentor, Fabio; Strindberg, Sophie Andersen; Nielsen, Line Hagner; Keller, Stephan Sylvest; Alstrøm, Tommy Sonne; Gundlach, Carsten; Müllertz, Anette; Marizza, Paolo; Boisen, Anja.

    In: Journal of Controlled Release, Vol. 268, 28.12.2017, p. 343-351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants. / Klitgaard, Mette; Sassene, Philip Jonas; Selen, Arzu; Müllertz, Anette; Berthelsen, Ragna.

    In: European Journal of Pharmaceutical Sciences, Vol. 109, 15.11.2017, p. 191-199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method. / Plum, Jakob; Madsen, Cecilie M; Teleki, Alexandra; Bevernage, Jan; da Costa Mathews, Claudia; Karlsson, Eva M; Carlert, Sara; Holm, Rene; Müller, Thomas; Matthews, Wayne; Sayers, Alice; Ojala, Krista; Tsinsman, Konstantin; Lingamaneni, Ram; Bergström, Christel As; Rades, Thomas; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 14, No. 12, 07.11.2017, p. 4161-4169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide. / Svagan, Anna Justina; Müllertz, Anette; Löbmann, Korbinian.

    In: The Journal of pharmacy and pharmacology, Vol. 69, No. 11, 11.2017, p. 1477-1484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems. / Tran, Thuy; Siqueira, Scheyla D V S; Amenitsch, Heinz; Rades, Thomas; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 108, 15.10.2017, p. 62-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model. / Borkar, Nrupa; Andersson, Daniel R.; Yang, Mingshi; Müllertz, Anette; Holm, René; Mu, Huiling.

    In: Journal of Pharmacy and Pharmacology, Vol. 69, No. 9, 09.2017, p. 1110-1115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug. / Larsen, A T; Holm, R; Müllertz, A.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 117, 08.2017, p. 308-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems. / Tran, Thuy; Siqueira, Scheyla D V S; Amenitsch, Heinz; Müllertz, Anette; Rades, Thomas.

    In: Journal of Controlled Release, Vol. 255, 10.06.2017, p. 45-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging. / Madelung, Peter; Bertelsen, Poul; Jacobsen, Jette; Mullertz, Anette; Ostergaard, Jesper.

    In: Journal of Drug Delivery Science and Technology, Vol. 39, 06.2017, p. 516-522.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery. / Löbmann, Korbinian; Wohlert, Jakob; Müllertz, Anette; Wågberg, Lars; Svagan, Anna J.

    In: Advanced Materials Interfaces, Vol. 4, No. 9, 1600655, 05.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine. / Jensen, Linda G.; Skautrup, Frederik B.; Müllertz, Anette; Abrahamsson, Bertil; Rades, Thomas; Priemel, Petra A.

    In: International Journal of Pharmaceutics, Vol. 522, No. 1-2, 30.04.2017, p. 74-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability. / Paulraj, Thomas; Riazanova, Anastasia V; Yao, Kun; Andersson, Richard L; Müllertz, Anette; Svagan, Anna J.

    In: Biomacromolecules, Vol. 18, No. 4, 10.04.2017, p. 1401-1410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems. / Mosgaard, Mette D; Sassene, Philip J; Mu, Huiling; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 106, No. 4, 04.2017, p. 1183-1186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens : in vivo and in vitro evaluations. / Siqueira, Scheyla D V S; Müllertz, Anette; Gräeser, Kirsten; Kasten, Georgia; Mu, Huiling; Rades, Thomas.

    In: A A P S Journal, Vol. 19, No. 2, 03.2017, p. 587-594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions. / Tran, Thuy; Fatouros, Dimitrios G; Vertzoni, Maria; Reppas, Christos; Müllertz, Anette.

    In: The Journal of pharmacy and pharmacology, Vol. 69, No. 3, 03.2017, p. 265-273.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants). / Kamstrup, Danna; Berthelsen, Ragna; Sassene, Philip Jonas; Selen, Arzu; Müllertz, Anette.

    In: A A P S PharmSciTech, Vol. 18, No. 2, 02.2017, p. 317-329.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging. / Markl, Daniel; Zeitler, J Axel; Rasch, Cecilie; Michaelsen, Maria Høtoft; Müllertz, Anette; Rantanen, Jukka; Rades, Thomas; Bøtker, Johan.

    In: Pharmaceutical Research, Vol. 34, No. 5, 2017, p. 1037–1052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs : A Case Study with Tadalafil and HPMC. / Fjelrad Christfort, Juliane; Christensen, Jakob Plum; Madsen, Cecilie Maria; Nielsen, Line Hagner; Sandau, Martin; Andersen, Klaus; Müllertz, Anette; Rades, Thomas.

    In: Molecular Pharmaceutics, Vol. 14, No. 12, 2017, p. 4154-4160.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil. / Khumpirapang, Nattakanwadee; Pikulkaew, Surachai; Müllertz, Anette; Rades, Thomas; Okonogi, Siriporn.

    In: PLOS ONE, Vol. 12, No. 11, e0188848, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2016
  42. Published

    Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems. / Svagan, Anna J; Benjamins, Jan-Willem; Al-Ansari, Zeinab; Shalom, Daniel Bar; Müllertz, Anette; Wågberg, Lars; Löbmann, Korbinian.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 244 , No. Part A, 12.11.2016, p. 74–82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Optimizing clinical drug product performance : applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid. / Dickinson, Paul A.; Kesisoglou, Filippos; Flanagan, Talia; Martinez, Marilyn N.; Mistry, Hitesh B.; Crison, John R.; Polli, James E.; Cruañes, Maria T.; Serajuddin, Abu T. M.; Müllertz, Anette; Cook, Jack A.; Selen, Arzu.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 11, 11.2016, p. 3243-3255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems. / Sassene, P J; Michaelsen, M H; Mosgaard, M D; Jensen, M.K.; Van Den Broek, E; Wasan, K M; Mu, H; Rades, T; Müllertz, A.

    In: Molecular Pharmaceutics, Vol. 13, No. 10, 03.10.2016, p. 3417-3426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development of a μDissolution-Permeation model with in situ drug concentration monitoring. / Berthelsen, Ragna; Byrialsen, Julie Pelle; Holm, René; Jacobsen, Jette; Abrahamsson, Bertil; Saabye, Lasse; Madelung, Peter; Müllertz, Anette.

    In: Journal of Drug Delivery Science and Technology, Vol. 35, 01.10.2016, p. 223-233.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Studying the propensity of compounds to supersaturate : a practical and broadly applicable approach. / Palmelund, Henrik; Madsen, Cecilie Maria; Christensen, Jakob Plum; Müllertz, Anette; Rades, Thomas.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 10, 10.2016, p. 3021-3029.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs. / Meng-Lund, Emil; Jacobsen, Jette; Müllertz, Anette; Jørgensen, Erling B; Holm, René.

    In: International Journal of Pharmaceutics, Vol. 515, No. 1-2, 30.09.2016, p. 125-131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Comparison of lipases for in vitro models of gastric digestion : lipolysis using two infant formulas as model substrates. / Sassene, P J; Fanø, M; Mu, H; Rades, T; Aquistapace, S; Schmitt, B; Cruz-Hernandez, C; Wooster, T J; Müllertz, A.

    In: Food & Function, Vol. 7, No. 9, 14.09.2016, p. 3989-3998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs. / Borkar, Nrupa Nitin; Holm, René; Yang, Mingshi; Müllertz, Anette; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 513, No. 1-2, 09.09.2016, p. 211-217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers. / Li, Ping; Nielsen, Hanne Mørck; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 9, 09.2016, p. 2743-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs. / Andersson, Sara B. E.; Alvebratt, Caroline; Bevernage, Jan; Bonneau, Damien; Mathews, Claudia da Costa ; Dattani, Rikesh; Edueng, Khadijah; He, Yan; Holm, René; Madsen, Cecilie Maria; Müller, Thomas; Muenster, Uwe; Müllertz, Anette; Ojala, Krista; Rades, Thomas; Sieger, Peter; Bergström, Christel A. S.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 9, 09.2016, p. 2864-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors. / Madsen, Cecilie Maria; Boyd, Ben; Rades, Thomas; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 91, 25.08.2016, p. 31-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Apomorphine and its esters : Differences in Caco-2 cell permeability and chylomicron affinity. / Borkar, Nrupa; Chen, Zhizhong; Saaby, Lasse; Müllertz, Anette; Håkansson, Anders E; Schönbeck, Christian; Yang, Mingshi; Holm, René; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 509, No. 1-2, 06.06.2016, p. 499–506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Polymeric microcontainers improve oral bioavailability of furosemide. / Nielsen, Line Hagner; Melero, Ana; Keller, Stephan Sylvest; Jacobsen, Jette; Garrigues, Teresa; Rades, Thomas; Müllertz, Anette; Boisen, Anja.

    In: International Journal of Pharmaceutics, Vol. 504, No. 1-2, 17.05.2016, p. 98-109.

    Research output: Contribution to journalJournal articleResearchpeer-review

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