Anette Müllertz

Anette Müllertz

Professor


  1. 2019
  2. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends. / Berthelsen, Ragna; Klitgaard, Mette; Rades, Thomas; Müllertz, Anette.

    In: Advanced Drug Delivery Reviews, Vol. 142, 29.06.2019, p. 35-49.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects. / Bergstrom, Christel A. S.; Box, Karl; Holm, Rene; Matthews, Wayne; McAllister, Mark; Mullertz, Anette; Rades, Thomas; Schaefer, Kerstin J.; Teleki, Alexandra.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 139, 06.2019, p. 101-114.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats. / Liu, Jingying; Werner, Ulrich; Funke, Mario; Besenius, Melissa; Saaby, Lasse; Fano, Mathias; Mu, Huiling; Mullertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 560, 05.04.2019, p. 377-384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration. / Butler, James; Hens, Bart; Vertzoni, Maria; Brouwers, Joachim; Berben, Philippe; Dressman, Jennifer; Andreas, Cord J.; Schaefer, Kerstin Julia; Mann, James; McAllister, Mark; Jamei, Masoud; Kostewicz, Edmund; Kesisoglou, Filippos; Langguth, Peter; Minekus, Mans; Mullertz, Anette; Schilderink, Ronald; Koziolek, Mirko; Jedamzik, Philipp; Weitschies, Werner; Reppas, Christos; Augustijns, Patrick.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 136, 03.2019, p. 70-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement. / Rune Jørgensen, Jacob; Leth Jepsen, Morten; Hagner Nielsen, Line; Dufva, Martin; Mørck Nielsen, Hanne; Rades, Thomas; Boisen, Anja; Müllertz, Anette.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 143, 2019, p. 98-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Polymeric Lids for Microcontainers for Oral Protein Delivery. / Mazzoni, Chiara; Jacobsen, Rasmus Due; Mortensen, Jacob; Jørgensen, Jacob Rune; Vaut, Lukas; Jacobsen, Jette; Gundlach, Carsten; Müllertz, Anette; Nielsen, Line Hagner; Boisen, Anja.

    In: Macromolecular Bioscience, Vol. 19, No. 5, 1900004, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Published

    In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp). / Khumpirapang, Nattakanwadee; Chaichit, Siripat; Jiranusornkul, Supat; Pikulkaew, Surachai; Müllertz, Anette; Okonogi, Siriporn.

    In: Aquaculture, Vol. 496, 01.11.2018, p. 176-184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers. / Blaabjerg, Lasse Ingerslev; Grohganz, Holger; Lindenberg, Eleanor; Löbmann, Korbinian; Mullertz, Anette ; Rades, Thomas.

    In: Pharmaceutics, Vol. 10, No. 4, 164, 21.09.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions. / Duraipandian, S.; Knopp, M. M.; Pollard, M. R.; Kerdoncuff, H.; Petersen, J. C.; Mullertz, A.

    In: Analytical Methods, Vol. 10, No. 29, 07.08.2018, p. 3589-3593.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine. / Ueda, Hiroshi; Wu, Wenqi; Lobmann, Korbinian; Grohganz, Holger; Mullertz, Anette; Rades, Thomas.

    In: Molecular Pharmaceutics, Vol. 15, No. 5, 05.2018, p. 2036-2044.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens. / Jorgensen, Scheyla Daniela Siqueira; Al Sawaf, Malak; Graeser, Kirsten; Mu, Huiling; Muellertz, Anette; Rades, Thomas.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 124, 03.2018, p. 116-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments. / Madsen, Cecilie Maria; Feng, Kung-I; Leithead, Andrew; Canfield, Nicole; Jørgensen, Søren Astrup; Müllertz, Anette; Rades, Thomas.

    In: European Journal of Pharmaceutical Sciences, Vol. 111, 01.2018, p. 311-319.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems. / Tran, Thuy; Chakraborty, Anjan; Xi, Xi; Bohets, Hugo; Cornett, Claus; Tsinman, Konstantin; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 107, No. 1, 01.2018, p. 103-112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin? / Vu, Hanh T.H.; Hook, Sarah M.; Siqueira, Scheyla D.; Müllertz, Anette; Rades, Thomas; McDowell, Arlene.

    In: International Journal of Pharmaceutics, Vol. 548, No. 1, 2018, p. 82-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus. / Johansson, Kristoffer Enøe; Plum, Jakob; Mosleh, Majid; Madsen, Cecilie Maria; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 107, No. 4, 2018, p. 1095-1103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems. / Kheawfu, Kantaporn; Pikulkaew, Surachai; Rades, Thomas; Müllertz, Anette; Okonogi, Siriporn.

    In: Journal of Drug Delivery Science and Technology, Vol. 46, 2018, p. 330-338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design. / Tran, Thuy; Rades, Thomas; Müllertz, Anette.

    In: Asian Journal of Pharmaceutical Sciences, Vol. 13, 2018, p. 536-545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility. / López-Barón , Nataly; Sagnelli, Domenico; Blennow, Andreas; Holse, Mette; Gao, Jun; Saaby, Lasse; Müllertz, Anette; Jespersen, Birthe P Møller; Vasanthan, Thava.

    In: Food Hydrocolloids, Vol. 79, 2018, p. 117-126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2017
  22. Published

    From concept to in vivo testing : Microcontainers for oral drug delivery. / Mazzoni, Chiara; Tentor, Fabio; Strindberg, Sophie Andersen; Nielsen, Line Hagner; Keller, Stephan Sylvest; Alstrøm, Tommy Sonne; Gundlach, Carsten; Müllertz, Anette; Marizza, Paolo; Boisen, Anja.

    In: Journal of Controlled Release, Vol. 268, 28.12.2017, p. 343-351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants. / Klitgaard, Mette; Sassene, Philip Jonas; Selen, Arzu; Müllertz, Anette; Berthelsen, Ragna.

    In: European Journal of Pharmaceutical Sciences, Vol. 109, 15.11.2017, p. 191-199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method. / Plum, Jakob; Madsen, Cecilie M; Teleki, Alexandra; Bevernage, Jan; da Costa Mathews, Claudia; Karlsson, Eva M; Carlert, Sara; Holm, Rene; Müller, Thomas; Matthews, Wayne; Sayers, Alice; Ojala, Krista; Tsinsman, Konstantin; Lingamaneni, Ram; Bergström, Christel As; Rades, Thomas; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 14, No. 12, 07.11.2017, p. 4161-4169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide. / Svagan, Anna Justina; Müllertz, Anette; Löbmann, Korbinian.

    In: The Journal of pharmacy and pharmacology, Vol. 69, No. 11, 11.2017, p. 1477-1484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems. / Tran, Thuy; Siqueira, Scheyla D V S; Amenitsch, Heinz; Rades, Thomas; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 108, 15.10.2017, p. 62-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model. / Borkar, Nrupa; Andersson, Daniel R.; Yang, Mingshi; Müllertz, Anette; Holm, René; Mu, Huiling.

    In: Journal of Pharmacy and Pharmacology, Vol. 69, No. 9, 09.2017, p. 1110-1115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug. / Larsen, A T; Holm, R; Müllertz, A.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 117, 08.2017, p. 308-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems. / Tran, Thuy; Siqueira, Scheyla D V S; Amenitsch, Heinz; Müllertz, Anette; Rades, Thomas.

    In: Journal of Controlled Release, Vol. 255, 10.06.2017, p. 45-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging. / Madelung, Peter; Bertelsen, Poul; Jacobsen, Jette; Mullertz, Anette; Ostergaard, Jesper.

    In: Journal of Drug Delivery Science and Technology, Vol. 39, 06.2017, p. 516-522.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery. / Löbmann, Korbinian; Wohlert, Jakob; Müllertz, Anette; Wågberg, Lars; Svagan, Anna J.

    In: Advanced Materials Interfaces, Vol. 4, No. 9, 1600655, 05.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine. / Jensen, Linda G.; Skautrup, Frederik B.; Müllertz, Anette; Abrahamsson, Bertil; Rades, Thomas; Priemel, Petra A.

    In: International Journal of Pharmaceutics, Vol. 522, No. 1-2, 30.04.2017, p. 74-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability. / Paulraj, Thomas; Riazanova, Anastasia V; Yao, Kun; Andersson, Richard L; Müllertz, Anette; Svagan, Anna J.

    In: Biomacromolecules, Vol. 18, No. 4, 10.04.2017, p. 1401-1410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems. / Mosgaard, Mette D; Sassene, Philip J; Mu, Huiling; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 106, No. 4, 04.2017, p. 1183-1186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens : in vivo and in vitro evaluations. / Siqueira, Scheyla D V S; Müllertz, Anette; Gräeser, Kirsten; Kasten, Georgia; Mu, Huiling; Rades, Thomas.

    In: A A P S Journal, Vol. 19, No. 2, 03.2017, p. 587-594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions. / Tran, Thuy; Fatouros, Dimitrios G; Vertzoni, Maria; Reppas, Christos; Müllertz, Anette.

    In: The Journal of pharmacy and pharmacology, Vol. 69, No. 3, 03.2017, p. 265-273.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants). / Kamstrup, Danna; Berthelsen, Ragna; Sassene, Philip Jonas; Selen, Arzu; Müllertz, Anette.

    In: A A P S PharmSciTech, Vol. 18, No. 2, 02.2017, p. 317-329.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging. / Markl, Daniel; Zeitler, J Axel; Rasch, Cecilie; Michaelsen, Maria Høtoft; Müllertz, Anette; Rantanen, Jukka; Rades, Thomas; Bøtker, Johan.

    In: Pharmaceutical Research, Vol. 34, No. 5, 2017, p. 1037–1052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs : A Case Study with Tadalafil and HPMC. / Fjelrad Christfort, Juliane; Christensen, Jakob Plum; Madsen, Cecilie Maria; Nielsen, Line Hagner; Sandau, Martin; Andersen, Klaus; Müllertz, Anette; Rades, Thomas.

    In: Molecular Pharmaceutics, Vol. 14, No. 12, 2017, p. 4154-4160.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil. / Khumpirapang, Nattakanwadee; Pikulkaew, Surachai; Müllertz, Anette; Rades, Thomas; Okonogi, Siriporn.

    In: PLOS ONE, Vol. 12, No. 11, e0188848, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2016
  42. Published

    Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems. / Svagan, Anna J; Benjamins, Jan-Willem; Al-Ansari, Zeinab; Shalom, Daniel Bar; Müllertz, Anette; Wågberg, Lars; Löbmann, Korbinian.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 244 , No. Part A, 12.11.2016, p. 74–82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Optimizing clinical drug product performance : applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid. / Dickinson, Paul A.; Kesisoglou, Filippos; Flanagan, Talia; Martinez, Marilyn N.; Mistry, Hitesh B.; Crison, John R.; Polli, James E.; Cruañes, Maria T.; Serajuddin, Abu T. M.; Müllertz, Anette; Cook, Jack A.; Selen, Arzu.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 11, 11.2016, p. 3243-3255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems. / Sassene, P J; Michaelsen, M H; Mosgaard, M D; Jensen, M.K.; Van Den Broek, E; Wasan, K M; Mu, H; Rades, T; Müllertz, A.

    In: Molecular Pharmaceutics, Vol. 13, No. 10, 03.10.2016, p. 3417-3426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development of a μDissolution-Permeation model with in situ drug concentration monitoring. / Berthelsen, Ragna; Byrialsen, Julie Pelle; Holm, René; Jacobsen, Jette; Abrahamsson, Bertil; Saabye, Lasse; Madelung, Peter; Müllertz, Anette.

    In: Journal of Drug Delivery Science and Technology, Vol. 35, 01.10.2016, p. 223-233.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Studying the propensity of compounds to supersaturate : a practical and broadly applicable approach. / Palmelund, Henrik; Madsen, Cecilie Maria; Christensen, Jakob Plum; Müllertz, Anette; Rades, Thomas.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 10, 10.2016, p. 3021-3029.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs. / Meng-Lund, Emil; Jacobsen, Jette; Müllertz, Anette; Jørgensen, Erling B; Holm, René.

    In: International Journal of Pharmaceutics, Vol. 515, No. 1-2, 30.09.2016, p. 125-131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Comparison of lipases for in vitro models of gastric digestion : lipolysis using two infant formulas as model substrates. / Sassene, P J; Fanø, M; Mu, H; Rades, T; Aquistapace, S; Schmitt, B; Cruz-Hernandez, C; Wooster, T J; Müllertz, A.

    In: Food & Function, Vol. 7, No. 9, 14.09.2016, p. 3989-3998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs. / Borkar, Nrupa Nitin; Holm, René; Yang, Mingshi; Müllertz, Anette; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 513, No. 1-2, 09.09.2016, p. 211-217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers. / Li, Ping; Nielsen, Hanne Mørck; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 9, 09.2016, p. 2743-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs. / Andersson, Sara B. E.; Alvebratt, Caroline; Bevernage, Jan; Bonneau, Damien; Mathews, Claudia da Costa ; Dattani, Rikesh; Edueng, Khadijah; He, Yan; Holm, René; Madsen, Cecilie Maria; Müller, Thomas; Muenster, Uwe; Müllertz, Anette; Ojala, Krista; Rades, Thomas; Sieger, Peter; Bergström, Christel A. S.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 9, 09.2016, p. 2864-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors. / Madsen, Cecilie Maria; Boyd, Ben; Rades, Thomas; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 91, 25.08.2016, p. 31-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Apomorphine and its esters : Differences in Caco-2 cell permeability and chylomicron affinity. / Borkar, Nrupa; Chen, Zhizhong; Saaby, Lasse; Müllertz, Anette; Håkansson, Anders E; Schönbeck, Christian; Yang, Mingshi; Holm, René; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 509, No. 1-2, 06.06.2016, p. 499–506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Polymeric microcontainers improve oral bioavailability of furosemide. / Nielsen, Line Hagner; Melero, Ana; Keller, Stephan Sylvest; Jacobsen, Jette; Garrigues, Teresa; Rades, Thomas; Müllertz, Anette; Boisen, Anja.

    In: International Journal of Pharmaceutics, Vol. 504, No. 1-2, 17.05.2016, p. 98-109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine. / Tran, Thuy; Xi, Xi; Rades, Thomas; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 502, No. 1-2, 11.04.2016, p. 151-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction. / Bøtker, Johan Peter; Rantanen, Jukka; Arnfast, Lærke; Doreth, Maria; Raijada, Dharaben Kaushikkumar; Löbmann, Korbinian; Madsen, Cecilie Maria; Khan, Jamal; Rades, Thomas; Müllertz, Anette; Hawley, Adrian; Thomas, Diana; Boyd, Ben J.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 100, 03.2016, p. 119-127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Dissolution Model Development: Formulation Effects and Filter Complications. / Berthelsen, Ragna; Holm, Rene; Jacobsen, Jette; Kristensen, Jakob; Abrahamsson, Bertil; Mullertz, Anette.

    In: Dissolution Technologies, Vol. 23, No. 1, 02.2016, p. 6-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS). / Michaelsen, Maria Hotoft; Wasan, Kishor M.; Sivak, Olena; Mullertz, Anette; Rades, Thomas.

    In: The A A P S Journal, Vol. 18, No. 1, 01.2016, p. 180-186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers. / Christiansen, Martin Lau; Holm, Rene; Abrahamsson, Bertil; Jacobsen, Jette; Kristensen, Jakob; Andersen, Jens Rikardt; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 84, 2016, p. 77-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release. / Svagan, Anna J.; Kusic, Anja; De Gobba, Cristian; Larsen, Flemming Hofmann; Sassene, Philip; Zhou, Qi; Van De Weert, Marco; Mullertz, Anette; Jørgensen, Bodil; Ulvskov, Peter.

    In: P L o S One, Vol. 11, No. 12, e0168050, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract. / Klindt-Toldam, Stine; Larsen, Susanne K.; Saaby, Lasse; Olsen, Louise R.; Svenstrup, Gitte; Müllertz, Anette; Knøchel, Susanne; Heimdal, Hanne; Nielsen, Dennis Sandris; Zielińska, Dorota.

    In: Lebensmittel - Wissenschaft und Technologie, Vol. 74, 2016, p. 404-410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. 2015
  63. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation. / Bøgh, Marie; García-Díaz, María; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 94, No. Part A, 09.2015, p. 136–143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems. / Mosgaard, Mette D; Sassene, Philip; Mu, Huiling; Rades, Thomas; Müllertz, Anette.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 94, 08.2015, p. 493-500.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats. / Nielsen, Line Hagner; Rades, Thomas; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 490, No. 1-2, 25.07.2015, p. 334-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    pH-triggered drug release from biodegradable microwells for oral drug delivery. / Nielsen, Line Hagner; Nagstrup, Johan; Gordon, Sarah; Keller, Stephan Sylvest; Østergaard, Jesper; Rades, Thomas; Müllertz, Anette; Boisen, Anja.

    In: Biomedical Microdevices, Vol. 17, 55, 06.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats. / Berthelsen, Ragna; Holm, Rene; Jacobsen, Jette; Kristensen, Jakob; Abrahamsson, Bertil; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 12, No. 4, 06.04.2015, p. 1062-1071.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Structural features of colloidal species in the human fasted upper small intestine. / Mullertz, Anette; Reppas, Christos; Psachoulias, Dimitrios; Vertzoni, Maria; Fatouros, Dimitrios G.

    In: Journal of Pharmacy and Pharmacology, Vol. 67, No. 4, 04.2015, p. 486-492.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase. / Bakala-N'Goma, Jean-Claude; Williams, Hywel D.; Sassene, Philip J.; Kleberg, Karen; Calderone, Marilyn; Jannin, Vincent; Igonin, Annabel; Partheil, Anette; Marchaud, Delphine; Jule, Eduardo; Vertommen, Jan; Maio, Mario; Blundell, Ross; Benameur, Hassan; Müllertz, Anette; Pouton, Colin W.; Porter, Christopher J. H.; Carriere, Frederic.

    In: Pharmaceutical Research, Vol. 32, No. 4, 04.2015, p. 1279-1287.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans. / Christiansen, Martin Lau; Müllertz, Anette; Garmer, Mats; Kristensen, Jakob; Jacobsen, Jette; Abrahamsson, Bertil; Holm, Rene.

    In: Journal of Pharmaceutical Sciences, Vol. 104, No. 1, 01.2015, p. 135-143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations : a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system. / Sassene, Philip J.; Mosgaard, Mette D.; Löbmann, Korbinian; Mu, Huiling; Larsen, Flemming Hofmann; Rades, Thomas; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 12, No. 11, 2015, p. 4067-4076.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media. / Borkar, Nrupa Nitin; Li, Boyang; Holm, René; Håkansson, Anders; Müllertz, Anette; Yang, Mingshi; Mu, Huiling.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 89, 2015, p. 216-223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Marine lipids and the bioavailability of omega-3 fatty acids. / Mu, Huiling; Müllertz, Anette.

    In: Current Nutrition and Food Science, Vol. 11, No. 3, 2015, p. 177-187.

    Research output: Contribution to journalReviewResearchpeer-review

  74. 2014
  75. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery : In vitro and in vivo evaluations of enteric coating and drug loading. / Li, Ping; Tan, Angel; Prestidge, Clive A; Nielsen, Hanne Mørck; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 477, No. 1-2, 30.12.2014, p. 390-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4 : proposing a new lipid formulation performance classification system. / Williams, Hywel D; Sassene, Philip; Kleberg, Karen; Calderone, Marilyn; Igonin, Annabel; Jule, Eduardo; Vertommen, Jan; Blundell, Ross; Benameur, Hassan; Müllertz, Anette; Porter, Christopher J H; Pouton, Colin W; Communicated on Behalf of the LFCS Consortium.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 8, 08.2014, p. 2441-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example. / Berthelsen, Ragna; Sjögren, Erik; Jacobsen, Jette; Kristensen, Jakob; Holm, René; Abrahamsson, Bertil; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 473, No. 1-2, 02.07.2014, p. 356-365.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin. / Christophersen, Philip C; Vaghela, Dimple; Müllertz, Anette; Yang, Mingshi; Nielsen, Hanne M; Mu, Huiling.

    In: A A P S Journal, Vol. 16, No. 4, 07.2014, p. 875-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems. / Heshmati, Nasim; Cheng, Xinlai; Dapat, Else; Sassene, Philip; Eisenbrand, Gerhard; Fricker, Gert; Müllertz, Anette.

    In: The Journal of pharmacy and pharmacology, Vol. 66, No. 11, 24.06.2014, p. 1567-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Early pharmaceutical profiling to predict oral drug absorption : current status and unmet needs. / Bergström, Christel A S; Holm, René; Jørgensen, Søren Astrup; Andersson, Sara B E; Artursson, Per; Beato, Stefania; Borde, Anders; Box, Karl; Brewster, Marcus; Dressman, Jennifer; Feng, Kung-I; Halbert, Gavin; Kostewicz, Edmund; McAllister, Mark; Muenster, Uwe; Thinnes, Julian; Taylor, Robert; Mullertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 57, 16.06.2014, p. 173-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    In vitro models for the prediction of in vivo performance of oral dosage forms. / Kostewicz, Edmund S; Abrahamsson, Bertil; Brewster, Marcus; Brouwers, Joachim; Butler, James; Carlert, Sara; Dickinson, Paul A; Dressman, Jennifer; Holm, René; Klein, Sandra; Mann, James; McAllister, Mark; Minekus, Mans; Muenster, Uwe; Müllertz, Anette; Verwei, Miriam; Vertzoni, Maria; Weitschies, Werner; Augustijns, Patrick.

    In: European Journal of Pharmaceutical Sciences, Vol. 57, 16.06.2014, p. 342-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour. / Nielsen, Line Hagner; Keller, Stephan Sylvest; Boisen, Anja; Müllertz, Anette; Rades, Thomas.

    In: Drug Delivery and Translational Research, Vol. 4, No. 3, 06.2014, p. 268-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Refining stability and dissolution rate of amorphous drug formulations. / Grohganz, Holger; Priemel, Petra A; Löbmann, Korbinian; Nielsen, Line Hagner; Laitinen, Riikka; Mullertz, Anette; Van den Mooter, Guy; Rades, Thomas.

    In: Expert Opinion on Drug Delivery, Vol. 11, No. 6, 06.2014, p. 977-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa. / Meng-Lund, Emil; Marxen, Eva; Pedersen, Anne Marie Lynge; Müllertz, Anette; Hyrup, Birgitte; Holm, Rene; Jacobsen, Jette.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 7, 13.05.2014, p. 2053-2061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate. / Thomas, Nicky; Richter, Katharina; Pedersen, Thomas B; Holm, René; Müllertz, Anette; Rades, Thomas.

    In: A A P S Journal, Vol. 16, No. 3, 02.04.2014, p. 539-549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation. / Christophersen, Philip Carsten; Zhang, Long; Müllertz, Anette; Nielsen, Hanne Mørck; Yang, Mingshi; Mu, Huiling.

    In: Pharmaceutical Research, Vol. 31, No. 9, 13.03.2014, p. 2420-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs. / Madelung, Peter; Ostergaard, Jesper; Bertelsen, Poul; Jørgensen, Erik V; Jacobsen, Jette; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 467, No. 1-2, 02.03.2014, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Miniaturized approach for excipient selection during the development of oral solid dosage form. / Raijada, Dharaben Kaushikkumar; Müllertz, Anette; Cornett, Claus; Munk, Tommy; Sonnergaard, Jørn; Rantanen, Jukka.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 3, 03.2014, p. 900-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract. / Pedersen, Pernille Barbre; Bar-Shalom, Daniel; Baldursdottir, Stefania; Vilmann, Peter; Müllertz, Anette.

    In: Pharmaceutical Research, Vol. 31, No. 8, 19.02.2014, p. 2044-2053.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect. / Meng-Lund, Emil; Jacobsen, Jette; Jin, Liang; Janfelt, Christian; Holm, René; Müllertz, Anette; Nicolazzo, Joseph A.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 4, 103, 15.02.2014, p. 1133-1141.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation. / Marizza, Paolo; Keller, Stephan S; Müllertz, Anette; Boisen, Anja.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 173, 10.01.2014, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption. / Bøgh, Marie; Baldursdóttir, Stefania G; Müllertz, Anette; Nielsen, Hanne M.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 87, 08.01.2014, p. 227-235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS). / Christiansen, Martin Lau; Holm, Rene; Kristensen, Jakob; Kreilgaard, Mads; Jacobsen, Jette; Abrahamsson, Bertil; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 57, 2014, p. 164-172.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Fed and fasted state gastro-intestinal in vitro lipolysis : In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS. / Christophersen, Philip Carsten B; Christiansen, Martin Lau; Holm, Rene; Kristensen, Jakob; Jacobsen, Jette; Abrahamsson, Bertil; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 57, 2014, p. 232-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium. / Borkar, Nrupa Nitin; Xia, Dengning; Holm, René; Gan, Yong; Müllertz, Anette; Yang, Mingshi; Mu, Huiling.

    In: European Journal of Pharmaceutical Sciences, Vol. 51, 2014, p. 204-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles. / Christophersen, P.; Vaghela, D.; Müllertz, Anette; Yang, Mingshi; Nielsen, Hanne Mørck; Mu, Huiling.

    2014. Abstract from 41st Controlled Release Society (CRS) Annual Meeting, Chicago, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  97. 2013
  98. Published

    Bioavailability of cinnarizine in dogs : effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis. / Larsen, Anne T; Åkesson, Pernilla; Juréus, Anna; Saaby, Lasse; Abu-Rmaileh, Ragheb; Abrahamsson, Bertil; Østergaard, Jesper; Müllertz, Anette.

    In: Pharmaceutical Research, Vol. 30, No. 12, 12.2013, p. 3101-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3 : understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations. / Williams, Hywel D; Sassene, Philip; Kleberg, Karen; Calderone, Marilyn; Igonin, Annabel; Jule, Eduardo; Vertommen, Jan; Blundell, Ross; Benameur, Hassan; Müllertz, Anette; Pouton, Colin W; Porter, Christopher J H; LFCS Consortium.

    In: Pharmaceutical Research, Vol. 30, No. 12, 12.2013, p. 3059-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution. / Nielsen, Line Hagner; Gordon, Sarah; Pajander, Jari Pekka; Østergaard, Jesper; Rades, Thomas; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 457, No. 1, 30.11.2013, p. 14-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. / Pedersen, Pernille Barbre; Vilmann, Peter; Bar-Shalom, Daniel; Müllertz, Anette; Baldursdottir, Stefania.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 85, No. 3, Pt B, 11.2013, p. 958-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats. / Nielsen, Line Hagner; Gordon, Sarah; Holm, René; Selen, Arzu; Rades, Thomas; Müllertz, Anette.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 85, No. 3 Pt B, 11.2013, p. 942-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy. / Müllertz, Anette; Fatouros, Dimitrios G; Vertzoni, Maria; Reppas, Christos.

    In: The Journal of pharmacy and pharmacology, Vol. 65, No. 10, 10.2013, p. 1482-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Bile salts and their importance for drug absorption. / Holm, René; Müllertz, Anette; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 453, No. 1, 30.08.2013, p. 44-55.

    Research output: Contribution to journalReviewResearchpeer-review

  105. Published

    Lipid-based formulations for oral administration of poorly water-soluble drugs. / Mu, Huiling; Holm, René; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 453, No. 1, 30.08.2013, p. 215-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis. / Christophersen, Philip Carsten B; Zhang, L.; Yang, M; Nielsen, H Mørck; Müllertz, A; Mu, H.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 85, No. 3, part A, 02.08.2013, p. 473-480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems. / Li, Ping; Nielsen, Hanne Mørck; Fano, Mathias; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 102, No. 8, 08.2013, p. 2689-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

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