Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. 2017
    2. Published

      Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

      Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

      Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

      Svagan, A. J., Mullertz, Anette & Löbmann, Korbinian, Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

      Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

      Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

      Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

      Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

      Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

      Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

      Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

      Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

      Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

      Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

      Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2016
    21. Published

      Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

      Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, Korbinian, 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

      Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

      Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

      Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

      Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

      Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

      Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs

      Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

      Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

      Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Polymeric microcontainers improve oral bioavailability of furosemide

      Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

      Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

      Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

      Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Evaluating Oral Drug Delivery Systems: Digestion Models.

      Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    40. Published

      Evaluating Oral Drug Delivery Systems: Dissolution Models.

      Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    41. Published

      Rhamnogalacturonan-I based microcapsules for targeted drug release

      Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. 2015
    44. Published

      Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

      Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

      Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      pH-triggered drug release from biodegradable microwells for oral drug delivery

      Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Structural features of colloidal species in the human fasted upper small intestine

      Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

      Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

      Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

      Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

      Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Marine lipids and the bioavailability of omega-3 fatty acids

      Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

      Research output: Contribution to journalReviewResearchpeer-review

    55. 2014
    56. Published

      Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

      Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

      Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

      Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      In vitro models for the prediction of in vivo performance of oral dosage forms

      Kostewicz, E. S., Abrahamsson, B., Brewster, M., Brouwers, J., Butler, J., Carlert, S., Dickinson, P. A., Dressman, J., Holm, R., Klein, S., Mann, J., McAllister, M., Minekus, M., Muenster, U., Mullertz, Anette , Verwei, M., Vertzoni, M., Weitschies, W. & Augustijns, P., 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 342-66 25 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

      Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Refining stability and dissolution rate of amorphous drug formulations

      Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

      Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

      Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Published

      Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

      Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Miniaturized approach for excipient selection during the development of oral solid dosage form

      Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract

      Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

      Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation

      Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In: Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

      Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

      Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium

      Borkar, N. N., Xia, D., Holm, R., Gan, Y., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 204-10 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

      Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    78. 2013
    79. Published

      Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

      Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & LFCS Consortium, L. C., Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3059-76 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

      Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

      Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats

      Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy

      Mullertz, Anette , Fatouros, D. G., Vertzoni, M. & Reppas, C., Oct 2013, In: The Journal of pharmacy and pharmacology. 65, 10, p. 1482-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Bile salts and their importance for drug absorption

      Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    86. Published

      Lipid-based formulations for oral administration of poorly water-soluble drugs

      Mu, Huiling, Holm, R. & Mullertz, Anette , 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 215-24 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

      Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck, Fano, M. & Mullertz, Anette , Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2689-98 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Recent developments in oral lipid-based drug delivery

      Thomas, N., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 375-382 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology

      Ren, S., Mu, Huiling, Alchaer, F., Chtatou, A. & Mullertz, Anette , May 2013, In: Drug Development and Industrial Pharmacy. 39, 5, p. 799-806 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

      Research output: Contribution to conferencePosterResearchpeer-review

    93. Published

      A new approach to dissolution testing by UV imaging and finite element simulations

      Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Development and rheological profiling of biosimilar mucus

      Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

      Research output: Contribution to journalConference articleResearchpeer-review

    95. Published

      Mucosal drug delivery: barriers, in vitro models and formulation strategies

      Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

      Research output: Contribution to journalReviewResearchpeer-review

    96. Published

      Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation

      Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Polymer selection for simulation of rheological properties of human gastric fluid

      Pedersen, P. B., Vilmann, P., Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 241-247

      Research output: Contribution to journalConference articleResearch

    98. Published

      Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

      Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug Simvastatin in dogs

      Thomas, N., Holm, R., Garmer, M., Karlsson, J. J., Mullertz, Anette & Rades, Thomas, 2013, In: A A P S Journal. 15, 1, p. 219-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    101. 2012
    102. Published

      Characterising lipid lipolysis and its implication in lipid-based formulation development

      Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In: The AAPS journal. 14, 4, p. 860-71 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    103. Published

      Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

      Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In: International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    104. Published

      In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

      Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: International Journal of Pharmaceutics. 441, 1-2, p. 323-333

      Research output: Contribution to journalJournal articleResearchpeer-review

    105. Published

      Influence of bile on the absorption of halofantrine from lipid-based formulations

      Holm, R., Tønsberg, H., Jørgensen, E. B., Abedinpour, P., Farsad, S. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 281-287

      Research output: Contribution to journalJournal articleResearchpeer-review

    106. Published

      Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems

      Thomas, N., Mullertz, Anette , Graf, A. & Rades, T., 2012, In: Journal of Pharmaceutical Sciences. 101, 5, p. 1721-1731

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 1302503