Anette Müllertz

Anette Müllertz

Professor

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    ORCID: 0000-0003-3020-8892

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    1. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Clinical studies with oral lipid based formulations of poorly soluble compounds

      Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

      Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

      Research output: Contribution to conference › Poster › Research

    5. Published

      Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

      Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

      Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

      Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Comparison of induction methods for supersaturation: pH shift versus solvent shift

      Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

      Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

      Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

      Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J. & 16 others, McAllister, M., Mullertz, Anette , O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentova, K., Vertzoni, M., De Wildt, S. N., Wilson, C. G. & Augustijns, P., 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

      Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

      Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Design of a self-unfolding delivery concept for oral administration of macromolecules

      Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

      Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In: Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

      Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

      Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Development and rheological profiling of biosimilar mucus

      Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

      Research output: Contribution to journal › Conference article › Research › peer-review

    21. Published

      Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

      Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

      Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

      Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

      Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

      Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Development of  in vitro methods for the evaluation of formulation performance

      Mullertz, Anette & Nielsen, F. S., 2005. 12 p.

      Research output: Contribution to conference › Paper › Research › peer-review

    29. Published

      Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

      Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Drug solubilization during simulated pediatric gastro-intestinal digestion

      Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33

      Research output: Contribution to journal › Journal article › Research

    34. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21

      Research output: Contribution to journal › Journal article › Communication

    35. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

      Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents

      Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

      Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

      Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound

      Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.

      Research output: Contribution to conference › Poster › Research

    42. Published

      Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug

      Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

      Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

      Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

      Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

      Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

      Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

      Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

      Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Enzymatic characterization of lipid-based drug delivery systems

      Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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