Anette Müllertz

Anette Müllertz

Professor


  1. Published

    In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability

    Fatouros, D. & Mullertz, Anette , 2008, In : Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76

    Research output: Contribution to journalReviewResearch

  2. Published

    In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

    Tran, T., Siqueira Jørgensen, Scheyla Daniela, Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In : Journal of Controlled Release. 255, p. 45-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

    Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In : International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

    Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In : Analytical Methods. 10, 29, p. 3589-3593

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A new approach to dissolution testing by UV imaging and finite element simulations

    Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, Henrik, 2013, In : Pharmaceutical Research. 30, 5, p. 1328-1337

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In : European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

    Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In : Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties

    Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

    Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In : International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An updated and simplified method for bile duct cannulation of rats

    Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In : Laboratory Animals. 44, 4, p. 373-376

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

    Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In : Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

    Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

    Borkar, N., Chen, Z., Saaby, L., Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In : International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In : Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin?

    Vu, H. T. H., Hook, S. M., Siqueira Jørgensen, Scheyla Daniela, Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In : International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

    Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In : Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Bile salts and their importance for drug absorption

    Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In : International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

    Larsen, A. T., Åkesson, P., Juréus, A., Saaby, L., Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In : Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state

    Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

    Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In : Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

    Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In : European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

    Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In : Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

    Abid, Z., Strindberg, Sophie , Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In : Lab on a Chip. 19, 17, p. 2905-2914 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

    Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In : Biomacromolecules. 18, 4, p. 1401-1410 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

    Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In : International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

    Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In : Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Biorelevant dissolution media

    Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  28. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

    Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In : Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

    Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In : International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

    Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In : Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Characterising lipid lipolysis and its implication in lipid-based formulation development

    Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In : The AAPS journal. 14, 4, p. 860-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

    Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In : Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30

    Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In : Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

    Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In : Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

    Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds

    Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In : Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In : Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

    Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In : European Journal of Pharmaceutical Sciences. 57, p. 164-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Clinical studies with oral lipid based formulations of poorly soluble compounds

    Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In : Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In : Pharmaceutical Research. 26, 2, p. 361-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

    Berthelsen, Ragna, Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In : International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

    Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Brodin, Birger, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In : European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Comparison of induction methods for supersaturation: pH shift versus solvent shift

    Plum, J., Bavnhoj, C., Palmelund, Henrik Brogaard, Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In : International Journal of Pharmaceutics. 573, 8 p., 118862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

    Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In : Food & Function. 7, 9, p. 3989-3998 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

    Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, Sophie , Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

    Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In : Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development and rheological profiling of biosimilar mucus

    Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In : Nordic Rheology Society Annual Transactions. 21, p. 233-240

    Research output: Contribution to journalConference articleResearchpeer-review

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