Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. Published

      pH-triggered drug release from biodegradable microwells for oral drug delivery

      Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

      Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

      Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

      Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

      Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Using in vitro dynamic lipolysis modeling as a tool for exploring IVIVC relationships for oral lipid-based formulations

      Mullertz, Anette & Fatourus, D. G., 2007, Oral lipid-based formulations: enhancing the bioviabillity of poorly water-soluble drugs. Hauss, D. J. (ed.). New York: Informa healtcare, p. 257-272

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    7. Published

      Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

      Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

      Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy

      Mullertz, Anette , Fatouros, D. G., Vertzoni, M. & Reppas, C., Oct 2013, In: The Journal of pharmacy and pharmacology. 65, 10, p. 1482-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      UNGAP best practice for improving solubility data quality of orally administered drugs

      Vertzoni, M., Alsenz, J., Augustijns, P., Bauer-Brandl, A., Bergström, C. A. S., Brouwers, J., Mullertz, Anette , Perlovich, G., Saal, C., Sugano, K. & Reppas, C., 1 Jan 2022, In: European Journal of Pharmaceutical Sciences. 168, 21 p., 106043.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

      Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    12. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Towards the development of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) containing trimethyl chitosan for the oral delivery of amphotericin B: In vitro assessment and cytocompatibility studies

      Kontogiannidou, E., Meikopoulos, T., Virgiliou, C., Bouropoulos, N., Gika, H., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., Apr 2020, In: Journal of Drug Delivery Science and Technology. 56, 9 p., 101524.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Towards analyzing the potential of exosomes to deliver microRNA therapeutics

      Giassafaki, L. N., Siqueira, S., Panteris, E., Psatha, K., Chatzopoulou, F., Aivaliotis, M., Tzimagiorgis, G., Mullertz, Anette , Fatouros, D. G. & Vizirianakis, I. S., 2021, In: Journal of Cellular Physiology. 236, 2, p. 1529-1544 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & LFCS Consortium, L. C., Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3059-76 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations

      Williams, H. D., Sassene, P., Kleberg, K., Bakala-N'Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: Journal of Pharmaceutical Sciences. 101, 9, p. 3360-3380

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

      Williams, H. D., Anby, M. U., Sassene, P., Kleberg, K., Bakala-N’Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Pouton, C. W. & Porter, C. J. H., 2012, In: Molecular Pharmaceutics. 9, 11, p. 3286-3300 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

      Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

      Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

      Research output: Contribution to conferencePosterResearch

    21. Published

      The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

      Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

      Moller, A., Schultz, H. B., Meola, T. R., Mullertz, Anette & Prestidge, C. A., 2021, In: European Journal of Pharmaceutical Sciences. 157, 10 p., 105640.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

      Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, K., Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

      Møller, Amalie Lykkemark, Schultz, H. B., Meola, T. R., Joyce, P., Mullertz, Anette & Prestidge, C. A., 2023, In: Pharmaceutics. 15, 1, 14 p., 284.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

      Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

      Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Tabletter med løse ender

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journalJournal articleResearch

    28. Published

      Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6 3 p.

      Research output: Contribution to journalJournal articleResearch

    29. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knøchel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

      Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug Simvastatin in dogs

      Thomas, N., Holm, R., Garmer, M., Karlsson, J. J., Mullertz, Anette & Rades, Thomas, 2013, In: A A P S Journal. 15, 1, p. 219-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

      Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

      Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

      Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

      Holm, R., Porter, C. J. H., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2002, In: Pharmaceutical Research. 19, 9, p. 1354-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Structured approach for designing drug-loaded solid products by binder jetting 3D printing

      Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: European Journal of Pharmaceutical Sciences. 178, 11 p., 106280.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Structural features of colloidal species in the human fasted upper small intestine

      Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering

      Fatouros, D. G., Deen, R., Arleth, Lise, Bergenstahl, B., Nielsen, F. S., Pedersen, J. S. & Mullertz, Anette , 2007, In: Pharmaceutical Research. 24, 10, p. 1844-1853 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

      Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Spatial confinement can lead to increased stability of amorphous indomethacin

      Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

      Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols

      Christensen, J. Ø., Schultz, K., Mollgaard, B., Kristensen, H. G. & Mullertz, Anette , 2004, In: European Journal of Pharmaceutical Sciences. 23, 3, p. 287-96 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

      Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

      Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

      Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

      Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, K., 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

      Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

      Abrahamsson, B., Mcallister, M., Augustijns, P., Zane, P., Butler, J., Holm, R., Langguth, P., Lindahl, A., Mullertz, Anette , Pepin, X., Rostami-hodjegan, A., Sjögren, E., Berntsson, M. & Lennernäs, H., 1 Jul 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 236-247 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

      Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

      Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

      Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    54. Published

      Selection of a lipase for development of an in vitro gastric lipid digestion model

      Larsen, A. T., Jensen, L. G., Hansen, K. K. & Mullertz, Anette , Nov 2010.

      Research output: Contribution to conferencePosterResearch

    55. Published

      SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

      Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

      Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Rhamnogalacturonan-I based microcapsules for targeted drug release

      Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Refining stability and dissolution rate of amorphous drug formulations

      Grohganz, Holger, Priemel, P. A., Löbmann, K., Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

      Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

      Research output: Contribution to conferencePosterResearch

    60. Published

      Recent developments in oral lipid-based drug delivery

      Thomas, N., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 375-382 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

      Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

      Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats

      Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck, Fano, M. & Mullertz, Anette , Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2689-98 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model

      Falavigna, M., Klitgaard, Mette, Berthelsen, R., Mullertz, Anette & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

      Sassene, P. J., Knopp, M. M., Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Poorly soluble drugs

      Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

      Research output: Contribution to journalEditorialResearch

    68. Published

      Polymeric microcontainers improve oral bioavailability of furosemide

      Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Polymeric Lids for Microcontainers for Oral Protein Delivery

      Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation

      Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In: Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Polymer selection for simulation of rheological properties of human gastric fluid

      Pedersen, P. B., Vilmann, P., Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 241-247

      Research output: Contribution to journalConference articleResearch

    72. Published

      Physicochemical characterization of simulated intestinal fed-state fluids containing lyso-phosphatidylcholine and cholesterol

      Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Dissolution Technologies. 16, 3, p. 47-50

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

      Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Phase transformations of amlodipine besylate solid forms

      Koradia, V. S., Lemos, A. F. F. D., Allesø, M., Diego, H. L. D., Ringkjøbing-Elema, M., Mullertz, Anette & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7, p. 2896-2910

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Oral delivery of peptides and proteins using lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , 2012, In: Expert Opinion on Drug Delivery. 9, 10, p. 1289-304 16 p.

      Research output: Contribution to journalReviewResearchpeer-review

    76. Published

      Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation

      Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

      Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Optimization of the in vitro lipolysis rate of SMEDDS containing cinnarizine

      Ulmann, C., Figueriedo-Larsen, M., Refsgaard, L., Hellekilde, J., Larsen, A., Nielsen, C., Olesen, P. & Mullertz, Anette , 2009.

      Research output: Contribution to conferencePosterResearch

    79. Published

      Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology

      Ren, S., Mu, Huiling, Alchaer, F., Chtatou, A. & Mullertz, Anette , May 2013, In: Drug Development and Industrial Pharmacy. 39, 5, p. 799-806 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

      Kubackova, J., Holas, O., Zbytovska, J., Vranikova, B., Zeng, G., Pavek, P. & Mullertz, Anette , Apr 2021, In: Pharmaceutics. 13, 4, 27 p., 459.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

      Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Mucosal drug delivery: barriers, in vitro models and formulation strategies

      Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

      Research output: Contribution to journalReviewResearchpeer-review

    83. Published

      Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis

      Serioli, L., Gruzinskyte, L., Zappalà, G., Hwu, E. T., Laksafoss, T. Z., Jensen, P. L., Demarchi, D., Mullertz, Anette , Boisen, A. & Zór, K., 2023, In: Lab on a Chip. 23, p. 1603-1612

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Morphological observations on a lipid-based drug delivery system during in vitro digestion

      Fatouros, D. G., Bergenstahl, B. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 31, 2, p. 85-94

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Published

      Miniaturized approach for excipient selection during the development of oral solid dosage form

      Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Milk osteopontin retains integrin-binding activity after in vitro gastrointestinal transit

      Christensen, B., Karlsen, N. J., Jorgensen, S. D. S., Jacobsen, L. N., Ostenfeld, M. S., Petersen, S. V., Mullertz, Anette & Sorensen, E. S., Jan 2020, In: Journal of Dairy Science. 103, 1, p. 42-51

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

      Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit

      Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In: The AAPS Journal. 12, 3, p. 465-472

      Research output: Contribution to journalReviewResearch

    90. Published

      Marine lipids and the bioavailability of omega-3 fatty acids

      Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

      Research output: Contribution to journalReviewResearchpeer-review

    91. Published

      Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols

      Holm, R., Porsgaard, T., Porter, H., Høy, C., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2006, In: European Journal of Lipid Science and Technology. 108, 9, p. 714-722 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Liquid self-microemulsifying drug delivery

      Mullertz, Anette & Grove, M., 2007, Oral lipid-based formulations: enhancing the bioavailability of poor water-soluble drugs. Hauss, D. J. (ed.). New York: Informa Healthcare, p. 107-128

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    94. Published

      Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

      Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Lipid-based formulations for oral administration of poorly water-soluble drugs

      Mu, Huiling, Holm, R. & Mullertz, Anette , 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 215-24 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis

      Larsen, A., Holm, R., Pedersen, M. L. & Mullertz, Anette , 2008, In: Pharmaceutical Research. 25, 12, p. 2769-2777

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

      Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

      Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

      Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

      Research output: Contribution to journalJournal articleResearchpeer-review

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