Anette Müllertz
Professor
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In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability
Fatouros, D. & Mullertz, Anette , 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76Research output: Contribution to journal › Review › Research
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In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery
Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems
Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs
Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions
Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593Research output: Contribution to journal › Journal article › Research › peer-review
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A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
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A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs
Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422Research output: Contribution to journal › Journal article › Research › peer-review
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A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour
Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model
Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.Research output: Contribution to journal › Journal article › Research › peer-review
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Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems
Klitgaard, Mette, Beilles, S., Sassene, P. J., Berthelsen, R. & Mullertz, Anette , 2020, In: Molecular Pharmaceutics. 17, 9, p. 3214-3222 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing
Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.Research output: Contribution to journal › Review › Research › peer-review
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Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties
Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116Research output: Contribution to journal › Journal article › Research › peer-review
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Amorphous is not always better—A dissolution study on solid state forms of carbamazepine
Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex
Liu, X., Berthelsen, R., Bar-Shalom, Daniel, Kjellerup Lind, T., Doutch, J. & Mullertz, Anette , 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.Research output: Contribution to journal › Journal article › Research › peer-review
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An updated and simplified method for bile duct cannulation of rats
Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, K., Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity
Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine
Ueda, H., Wu, W., Lobmann, K., Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044Research output: Contribution to journal › Journal article › Research › peer-review
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Are phytosomes a superior nanodelivery system for the antioxidant rutin?
Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids
Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499Research output: Contribution to journal › Journal article › Research › peer-review
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Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect
Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile salts and their importance for drug absorption
Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis
Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state
Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562Research output: Contribution to journal › Journal article › Research › peer-review
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Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides
Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state
Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15Research output: Contribution to journal › Journal article › Research › peer-review
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Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats
Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery
Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability
Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol
Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant dissolution media
Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
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Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity
Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bovine Milk-Derived Emulsifiers Increase Triglyceride Absorption in Newborn Formula-Fed Pigs
Knudsen, K. B. K., Heerup, C., Jensen, T. R. S., Geng, X., Drachmann, N., Nordby, P., Jeppesen, Palle Bekker, Ifaoui, I., Mullertz, Anette , Sangild, Per Torp, Ostenfeld, M. S. & Thymann, Thomas, 2021, In: Nutrients. 13, 2, 15 p., 410.Research output: Contribution to journal › Journal article › Research › peer-review
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Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs
Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery
Löbmann, K., Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterising lipid lipolysis and its implication in lipid-based formulation development
Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In: The AAPS journal. 14, 4, p. 860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies
Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30
Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In: Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities
Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds
Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In: Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the hydrodynamics in a miniaturized dissolution apparatus
Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)
Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical studies with oral lipid based formulations of poorly soluble compounds
Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products
Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512Research output: Contribution to journal › Journal article › Research › peer-review
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Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products
Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.Research output: Contribution to conference › Poster › Research
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Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products
Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374Research output: Contribution to journal › Journal article › Research › peer-review
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Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example
Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug
Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of induction methods for supersaturation: pH shift versus solvent shift
Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J., McAllister, M., Mullertz, Anette , O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentova, K., Vertzoni, M., De Wildt, S. N., Wilson, C. G. & Augustijns, P., 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.Research output: Contribution to journal › Review › Research › peer-review
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Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin
Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
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Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection
Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In: Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880Research output: Contribution to journal › Journal article › Research › peer-review
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Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats
Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems
Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and rheological profiling of biosimilar mucus
Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240Research output: Contribution to journal › Conference article › Research › peer-review
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Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs
Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC
Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems
Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a μDissolution-Permeation model with in situ drug concentration monitoring
Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit
Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms
Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270Research output: Contribution to journal › Journal article › Research › peer-review
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Development of in vitro methods for the evaluation of formulation performance
Mullertz, Anette & Nielsen, F. S., 2005. 12 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro
Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution Model Development: Formulation Effects and Filter Complications
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug solubilization during simulated pediatric gastro-intestinal digestion
Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33Research output: Contribution to journal › Journal article › Research
- Published
Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21Research output: Contribution to journal › Journal article › Communication
- Published
Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs
Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats
Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents
Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture
Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers
Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound
Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.Research output: Contribution to conference › Poster › Research
- Published
Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug
Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor
Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats
Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion
Heerup, C., Ebbesen, M. F., Geng, X., Madsen, Sofie Falkenløve, Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model
Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system
Sassene, P. J., Mosgaard, M. D., Löbmann, K., Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enzymatic characterization of lipid-based drug delivery systems
Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method
Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine
Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302503
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
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Rhamnogalacturonan-I based microcapsules for targeted drug release
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