Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. Published

      In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability

      Fatouros, D. & Mullertz, Anette , 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76

      Research output: Contribution to journalReviewResearch

    2. Published

      In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery

      Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

      Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

      Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      A new approach to dissolution testing by UV imaging and finite element simulations

      Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

      Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

      Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

      Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems

      Klitgaard, Mette, Beilles, S., Sassene, P. J., Berthelsen, R. & Mullertz, Anette , 2020, In: Molecular Pharmaceutics. 17, 9, p. 3214-3222 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing

      Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.

      Research output: Contribution to journalReviewResearchpeer-review

    13. Published

      Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties

      Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

      Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex

      Liu, X., Berthelsen, R., Bar-Shalom, Daniel, Kjellerup Lind, T., Doutch, J. & Mullertz, Anette , 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      An updated and simplified method for bile duct cannulation of rats

      Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

      Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

      Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, K., Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

      Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

      Ueda, H., Wu, W., Lobmann, K., Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Are phytosomes a superior nanodelivery system for the antioxidant rutin?

      Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

      Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

      Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Bile salts and their importance for drug absorption

      Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    25. Published

      Binder jetting 3D printing in fabricating pharmaceutical solid products for precision medicine

      Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2024, In: Basic & clinical pharmacology & toxicology. 134, 3, p. 325-332

      Research output: Contribution to journalReviewResearchpeer-review

    26. Published

      Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

      Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state

      Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

      Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

      Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

      Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

      Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

      Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

      Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

      Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

      Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Biorelevant dissolution media

      Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    37. Published

      Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

      Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

      Research output: Contribution to journalReviewResearchpeer-review

    38. Published

      Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

      Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Bovine Milk-Derived Emulsifiers Increase Triglyceride Absorption in Newborn Formula-Fed Pigs

      Knudsen, K. B. K., Heerup, C., Jensen, T. R. S., Geng, X., Drachmann, N., Nordby, P., Jeppesen, Palle Bekker, Ifaoui, I., Mullertz, Anette , Sangild, Per Torp, Ostenfeld, M. S. & Thymann, Thomas, 2021, In: Nutrients. 13, 2, 15 p., 410.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

      Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

      Löbmann, K., Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Characterising lipid lipolysis and its implication in lipid-based formulation development

      Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In: The AAPS journal. 14, 4, p. 860-71 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

      Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30

      Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In: Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

      Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds

      Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In: Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Characterization of the hydrodynamics in a miniaturized dissolution apparatus

      Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Clinical studies with oral lipid based formulations of poorly soluble compounds

      Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

      Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

      Research output: Contribution to conferencePosterResearch

    53. Published

      Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

      Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

      Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

      Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Comparison of induction methods for supersaturation: pH shift versus solvent shift

      Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

      Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

      Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

      Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J. & 16 others, McAllister, M., Mullertz, Anette , O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentova, K., Vertzoni, M., De Wildt, S. N., Wilson, C. G. & Augustijns, P., 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.

      Research output: Contribution to journalReviewResearchpeer-review

    62. Published

      Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

      Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

      Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Design of a self-unfolding delivery concept for oral administration of macromolecules

      Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

      Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In: Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

      Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

      Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Published

      Development and rheological profiling of biosimilar mucus

      Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

      Research output: Contribution to journalConference articleResearchpeer-review

    69. Published

      Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

      Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

      Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

      Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

      Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

      Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Development of  in vitro methods for the evaluation of formulation performance

      Mullertz, Anette & Nielsen, F. S., 2005. 12 p.

      Research output: Contribution to conferencePaperResearchpeer-review

    77. Published

      Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

      Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Drug solubilization during simulated pediatric gastro-intestinal digestion

      Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33

      Research output: Contribution to journalJournal articleResearch

    82. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

      Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents

      Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

      Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Published

      Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

      Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound

      Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.

      Research output: Contribution to conferencePosterResearch

    89. Published

      Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug

      Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

      Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

      Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

      Heerup, C., Ebbesen, M. F., Geng, X., Madsen, Sofie Falkenløve, Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

      Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

      Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

      Sassene, P. J., Mosgaard, M. D., Löbmann, K., Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

      Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Enzymatic characterization of lipid-based drug delivery systems

      Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method

      Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      Evaluating Oral Drug Delivery Systems: Digestion Models.

      Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    100. Published

      Evaluating Oral Drug Delivery Systems: Dissolution Models.

      Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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