Anette Müllertz

Anette Müllertz

Professor


  1. Published

    In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability

    Fatouros, D. & Mullertz, Anette , 2008, In : Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76

    Research output: Contribution to journalReviewResearch

  2. Published

    In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

    Tran, T., Siqueira Jørgensen, Scheyla Daniela, Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In : Journal of Controlled Release. 255, p. 45-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

    Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In : International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

    Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In : Analytical Methods. 10, 29, p. 3589-3593

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A new approach to dissolution testing by UV imaging and finite element simulations

    Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, Henrik, 2013, In : Pharmaceutical Research. 30, 5, p. 1328-1337

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In : European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

    Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In : Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties

    Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

    Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In : International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An updated and simplified method for bile duct cannulation of rats

    Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In : Laboratory Animals. 44, 4, p. 373-376

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

    Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In : Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

    Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

    Borkar, N., Chen, Z., Saaby, L., Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In : International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In : Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin?

    Vu, H. T. H., Hook, S. M., Siqueira Jørgensen, Scheyla Daniela, Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In : International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

    Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In : Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Bile salts and their importance for drug absorption

    Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In : International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

    Larsen, A. T., Åkesson, P., Juréus, A., Saaby, L., Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In : Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state

    Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

    Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In : Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

    Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In : European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

    Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In : Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

    Abid, Z., Strindberg, Sophie , Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In : Lab on a Chip. 19, 17, p. 2905-2914 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

    Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In : Biomacromolecules. 18, 4, p. 1401-1410 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

    Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In : International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

    Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In : Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Biorelevant dissolution media

    Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  28. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

    Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In : Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

    Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In : International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

    Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In : Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Characterising lipid lipolysis and its implication in lipid-based formulation development

    Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In : The AAPS journal. 14, 4, p. 860-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

    Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In : Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30

    Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In : Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

    Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In : Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

    Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds

    Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In : Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In : Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

    Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In : European Journal of Pharmaceutical Sciences. 57, p. 164-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Clinical studies with oral lipid based formulations of poorly soluble compounds

    Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In : Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In : Pharmaceutical Research. 26, 2, p. 361-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

    Berthelsen, Ragna, Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In : International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

    Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Brodin, Birger, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In : European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Comparison of induction methods for supersaturation: pH shift versus solvent shift

    Plum, J., Bavnhoj, C., Palmelund, Henrik, Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In : International Journal of Pharmaceutics. 573, 8 p., 118862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

    Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In : Food & Function. 7, 9, p. 3989-3998 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

    Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, Sophie , Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

    Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In : Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development and rheological profiling of biosimilar mucus

    Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In : Nordic Rheology Society Annual Transactions. 21, p. 233-240

    Research output: Contribution to journalConference articleResearchpeer-review

  51. Published

    Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

    Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In : Molecular Pharmaceutics. 14, 12, p. 4154-4160

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

    Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Development of a μDissolution-Permeation model with in situ drug concentration monitoring

    Berthelsen, Ragna, Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saabye, L., Madelung, P. & Mullertz, Anette , 1 Oct 2016, In : Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In : European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Development of  in vitro methods for the evaluation of formulation performance

    Mullertz, Anette & Nielsen, F. S., 2005. 12 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  56. Published

    Dissolution Model Development: Formulation Effects and Filter Complications

    Berthelsen, Ragna, Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In : Dissolution Technologies. 23, 1, p. 6-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

    Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In : Journal of Drug Delivery Science and Technology. 39, p. 516-522

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

    Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In : Dansk Kemi. 89, 8, p. 30-33

    Research output: Contribution to journalJournal articleResearch

  59. Published

    Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

    Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In : Lægemiddelforskning. p. 20-21

    Research output: Contribution to journalJournal articleCommunication

  60. Published

    Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

    Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In : European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

    Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In : Journal of Pharmacy and Pharmacology. 63, p. 817-824

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

    Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In : European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

    Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In : Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

    Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In : European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound

    Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.

    Research output: Contribution to conferencePosterResearch

  66. Published

    Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug

    Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In : European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

    Strindberg, Sophie , Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In : European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

    Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In : Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

    Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In : Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

    Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In : Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Enzymatic characterization of lipid-based drug delivery systems

    Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In : Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Evaluating Oral Drug Delivery Systems: Digestion Models.

    Berthelsen, Ragna, Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  73. Published

    Evaluating Oral Drug Delivery Systems: Dissolution Models.

    Berthelsen, Ragna, Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  74. Published

    Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

    Eliasen, J. N., Berthelsen, Ragna, Slot, A. L. & Mullertz, Anette , 2020, In : Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

    Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In : Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

    Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In : Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

    Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  78. Published

    Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

    Dalskov Mosgaard, M., Strindberg, Sophie , Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In : International Journal of Pharmaceutics. 570, 118658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides

    Holm, R., Porter, C. J. H., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2003, In : European Journal of Pharmaceutical Sciences. 20, 1, p. 91-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

    Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In : International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

    Siqueira Jørgensen, Scheyla Daniela, Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In : Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

    Research output: Contribution to journalLetterResearchpeer-review

  82. Published

    Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract

    Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In : Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

    Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In : European Journal of Pharmaceutical Sciences. 57, p. 232-239

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

    Michaelsen, M. H., Siqueira Jørgensen, Scheyla Daniela, Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

    Svagan, A. J., Mullertz, Anette & Löbmann, Korbinian, Nov 2017, In : The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

    Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In : International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 25 Sep 2020, In : International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

    Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In : Asian Journal of Pharmaceutical Sciences. 13, p. 536-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    From concept to in vivo testing: Microcontainers for oral drug delivery

    Mazzoni, C., Tentor, F., Strindberg, Sophie , Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 343-351 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

    Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In : Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

    López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, L., Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., 2018, In : Food Hydrocolloids. 79, p. 117-126 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

    Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  94. Published

    Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

    Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In : International Journal of Pharmaceutics. 467, 1-2, p. 1-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

    Bannow, Jacob, Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In : International Journal of Pharmaceutics. 575, 1188960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

    Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In : A A P S Journal. 16, 3, p. 539-549

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

    Kamstrup, D., Berthelsen, Ragna, Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In : A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, Jacob Rune, Yu, F., Ramakrishnan, Venkatasubramanian, Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In : Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

    Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In : Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

    Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In : The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 3 Next

ID: 1302503