Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. 2023
    2. Published

      In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex

      Liu, X., Berthelsen, R., Bar-Shalom, Daniel, Kjellerup Lind, T., Doutch, J. & Mullertz, Anette , 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

      Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

      Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

      Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis

      Serioli, L., Gruzinskyte, L., Zappalà, G., Hwu, E. T., Laksafoss, T. Z., Jensen, P. L., Demarchi, D., Mullertz, Anette , Boisen, A. & Zór, K., 2023, In: Lab on a Chip. 23, p. 1603-1612

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

      Møller, Amalie Lykkemark, Schultz, H. B., Meola, T. R., Joyce, P., Mullertz, Anette & Prestidge, C. A., 2023, In: Pharmaceutics. 15, 1, 14 p., 284.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2022
    11. Published

      UNGAP best practice for improving solubility data quality of orally administered drugs

      Vertzoni, M., Alsenz, J., Augustijns, P., Bauer-Brandl, A., Bergström, C. A. S., Brouwers, J., Mullertz, Anette , Perlovich, G., Saal, C., Sugano, K. & Reppas, C., 1 Jan 2022, In: European Journal of Pharmaceutical Sciences. 168, 21 p., 106043.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing

      Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.

      Research output: Contribution to journalReviewResearchpeer-review

    13. Published

      Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

      Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

      Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

      Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

      Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Formulation, characterization and in-vitro evaluation of self-nanoemulsifying drug delivery system containing rhamnolipid biosurfactant

      Khan, Muhammad Ayub, Ullah, K., Rahman, N. U., Mahmood, A., Mullertz, Anette , Mannan, A., Murtaza, G. & Khan, S. A., 2022, In: Journal of Drug Delivery Science and Technology. 75, 9 p., 103673.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats

      Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

      Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

      Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Structured approach for designing drug-loaded solid products by binder jetting 3D printing

      Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: European Journal of Pharmaceutical Sciences. 178, 11 p., 106280.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

      Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2021
    24. Published

      Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

      Kubackova, J., Holas, O., Zbytovska, J., Vranikova, B., Zeng, G., Pavek, P. & Mullertz, Anette , Apr 2021, In: Pharmaceutics. 13, 4, 27 p., 459.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery

      Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Bovine Milk-Derived Emulsifiers Increase Triglyceride Absorption in Newborn Formula-Fed Pigs

      Knudsen, K. B. K., Heerup, C., Jensen, T. R. S., Geng, X., Drachmann, N., Nordby, P., Jeppesen, Palle Bekker, Ifaoui, I., Mullertz, Anette , Sangild, Per Torp, Ostenfeld, M. S. & Thymann, Thomas, 2021, In: Nutrients. 13, 2, 15 p., 410.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

      Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J., McAllister, M., Mullertz, Anette , O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentova, K., Vertzoni, M., De Wildt, S. N., Wilson, C. G. & Augustijns, P., 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.

      Research output: Contribution to journalReviewResearchpeer-review

    28. Published

      Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

      Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

      Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Design of a self-unfolding delivery concept for oral administration of macromolecules

      Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

      Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

      Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Drug solubilization during simulated pediatric gastro-intestinal digestion

      Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

      Heerup, C., Ebbesen, M. F., Geng, X., Madsen, Sofie Falkenløve, Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method

      Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Exploring Porcine Gastric and Intestinal Fluids using Microscopic and Solubility Estimates: Impact of Placebo Self-Emulsifying Drug Delivery System Administration to Inform Bio-Predictive in vitro Tools

      Bennett-Lenane, H., Jørgensen, J. R., Koehl, N. J., Henze, L. J., O'Shea, J. P., Mullertz, Anette & Griffin, B. T., 2021, In: European Journal of Pharmaceutical Sciences. 161, 11 p., 105778.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol

      Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

      Dahlgren, D., Venczel, M., Ridoux, J. P., Skjöld, C., Mullertz, Anette , Holm, R., Augustijns, P., Hellström, P. M. & Lennernäs, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 163, p. 240-251

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

      Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Hot punching for loading of biodegradable microcontainers with budesonide-Soluplus film

      Abid, Z., Andreoli, F., Kristensen, M. N., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2021, In: Biomedical Microdevices. 23, 11 p., 37.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies

      Grundy, M. M. L., Abrahamse, E., Almgren, A., Alminger, M., Andres, A., Ariëns, R. M. C., Bastiaan-Net, S., Bourlieu-Lacanal, C., Brodkorb, A., Bronze, M. R., Comi, I., Couëdelo, L., Dupont, D., Durand, A., El, S. N., Grauwet, T., Heerup, C., Heredia, A., Infantes Garcia, M. R., Jungnickel, C., Kłosowska-Chomiczewska, I. E., Létisse, M., Macierzanka, A., Mackie, A. R., McClements, D. J., Menard, O., Meynier, A., Michalski, M. C., Mulet-Cabero, A. I., Mullertz, Anette , Payeras Perelló, F. M., Peinado, I., Robert, M., Secouard, S., Serra, A. T., Silva, S. D., Thomassen, G., Tullberg, C., Undeland, I., Vaysse, C., Vegarud, G. E., Verkempinck, S. H. E., Viau, M., Zahir, M., Zhang, R. & Carrière, F., 2021, In: Journal of Functional Foods. 82, 104497.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model

      Falavigna, M., Klitgaard, Mette, Berthelsen, R., Mullertz, Anette & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

      Moller, A., Schultz, H. B., Meola, T. R., Mullertz, Anette & Prestidge, C. A., 2021, In: European Journal of Pharmaceutical Sciences. 157, 10 p., 105640.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Towards analyzing the potential of exosomes to deliver microRNA therapeutics

      Giassafaki, L. N., Siqueira, S., Panteris, E., Psatha, K., Chatzopoulou, F., Aivaliotis, M., Tzimagiorgis, G., Mullertz, Anette , Fatouros, D. G. & Vizirianakis, I. S., 2021, In: Journal of Cellular Physiology. 236, 2, p. 1529-1544 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

      Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

      Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. 2020
    48. Published

      Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

      Abrahamsson, B., Mcallister, M., Augustijns, P., Zane, P., Butler, J., Holm, R., Langguth, P., Lindahl, A., Mullertz, Anette , Pepin, X., Rostami-hodjegan, A., Sjögren, E., Berntsson, M. & Lennernäs, H., 1 Jul 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 236-247 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

      Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Towards the development of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) containing trimethyl chitosan for the oral delivery of amphotericin B: In vitro assessment and cytocompatibility studies

      Kontogiannidou, E., Meikopoulos, T., Virgiliou, C., Bouropoulos, N., Gika, H., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., Apr 2020, In: Journal of Drug Delivery Science and Technology. 56, 9 p., 101524.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Poorly soluble drugs

      Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

      Research output: Contribution to journalEditorialResearch

    52. Published

      In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

      Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Comparison of induction methods for supersaturation: pH shift versus solvent shift

      Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Milk osteopontin retains integrin-binding activity after in vitro gastrointestinal transit

      Christensen, B., Karlsen, N. J., Jorgensen, S. D. S., Jacobsen, L. N., Ostenfeld, M. S., Petersen, S. V., Mullertz, Anette & Sorensen, E. S., Jan 2020, In: Journal of Dairy Science. 103, 1, p. 42-51

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

      Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems

      Klitgaard, Mette, Beilles, S., Sassene, P. J., Berthelsen, R. & Mullertz, Anette , 2020, In: Molecular Pharmaceutics. 17, 9, p. 3214-3222 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

      Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents

      Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

      Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

      Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Evaluation of self -emulsifying drug delivery systems for oral insulin delivery using an in vitro model simulating the intestinal proteolysis

      Liu, J., Hirschberg, C., Fano, M., Mu, Huiling & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

      Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, K., Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published
    64. Published

      Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

      Stillhart, C., Vucicevic, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljus, G., Mooij, M. G., Parrott, N., Ungell, A. -., de Wildt, S. N., Orlu, M., Klein, S. & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 28 p., 105280.

      Research output: Contribution to journalReviewResearchpeer-review

    65. Published

      Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

      Bannow, J., Yorulmaz, Y., Löbmann, K., Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B

      Kontogiannidou, E., Meikopoulos, T., Gika, H., Panteris, E., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., 2020, In: Pharmaceutics. 12, 8, 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products [incl, correction]

      Selen, A., Mullertz, Anette , Kesisoglou, F., Ho, R. J. Y., Cook, J. A., Dickinson, P. A. & Flanagan, T., 2020, In: AAPS Journal. 22, 5, 20 p., 97.

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Published

      Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

      Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. 2019
    70. Published

      Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

      Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

      Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

      Research output: Contribution to journalReviewResearchpeer-review

    72. Published

      Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

      Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

      Research output: Contribution to journalReviewResearchpeer-review

    73. Published

      SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

      Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

      Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, Anette , Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W., Reppas, C. & Augustijns, P., Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

      Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

      Research output: Contribution to journalLetterResearchpeer-review

    76. Published

      Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

      Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

      Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

      Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

      Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development

      Zane, P., Gieschen, H., Kersten, E., Mathias, N., Ollier, C., Johansson, P., Van den Bergh, A., Van Hemelryck, S., Reichel, A., Rotgeri, A., Schäfer, K., Mullertz, Anette & Langguth, P., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 222-231 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

      Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Polymeric Lids for Microcontainers for Oral Protein Delivery

      Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

      Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    84. Published

      Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

      Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. 2018
    86. Published

      In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)

      Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

      Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, K., Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

      Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

      López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, Lasse, Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., Jun 2018, In: Food Hydrocolloids. 79, p. 117-126 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

      Ueda, H., Wu, W., Lobmann, K., Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

      Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

      Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

      Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Are phytosomes a superior nanodelivery system for the antioxidant rutin?

      Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Characterization of the hydrodynamics in a miniaturized dissolution apparatus

      Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

      Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

      Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. 2017
    99. Published

      From concept to in vivo testing: Microcontainers for oral drug delivery

      Mazzoni, C., Tentor, F., Strindberg, S. A., Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In: Journal of Controlled Release. 268, p. 343-351 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

      Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    101. Published

      Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

      Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

      Research output: Contribution to journalJournal articleResearchpeer-review

    102. Published

      Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

      Svagan, A. J., Mullertz, Anette & Löbmann, K., Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    103. Published

      Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    104. Published

      Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

      Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

      Research output: Contribution to journalJournal articleResearchpeer-review

    105. Published

      Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

      Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    106. Published

      In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    107. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    108. Published

      Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

      Löbmann, K., Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    109. Published

      Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

      Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    110. Published

      Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

      Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    111. Published

      High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

      Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    112. Published

      Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

      Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    113. Published

      Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    114. Published

      In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

      Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    115. Published

      Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

      Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    116. Published

      Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

      Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

      Research output: Contribution to journalJournal articleResearchpeer-review

    117. Published

      Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

      Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

      Research output: Contribution to journalJournal articleResearchpeer-review

    118. 2016
    119. Published

      Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

      Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, K., 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    120. Published

      Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

      Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    121. Published

      In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

      Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    122. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    123. Published

      Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

      Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    124. Published

      Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

      Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    125. Published

      Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

      Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    126. Published

      In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

      Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    127. Published

      Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    128. Published

      Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs

      Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    129. Published

      Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

      Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    130. Published

      Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

      Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    131. Published

      Polymeric microcontainers improve oral bioavailability of furosemide

      Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    132. Published

      Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

      Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    133. Published

      Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

      Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, K., Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    134. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    135. Published

      The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

      Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    136. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    137. Published

      Evaluating Oral Drug Delivery Systems: Digestion Models.

      Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    138. Published

      Evaluating Oral Drug Delivery Systems: Dissolution Models.

      Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    139. Published

      Rhamnogalacturonan-I based microcapsules for targeted drug release

      Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

      Research output: Contribution to journalJournal articleResearchpeer-review

    140. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knøchel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    141. 2015
    142. Published

      Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

      Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    143. Published

      Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

      Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    144. Published

      Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    145. Published

      pH-triggered drug release from biodegradable microwells for oral drug delivery

      Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

      Research output: Contribution to journalJournal articleResearchpeer-review

    146. Published

      Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    147. Published

      Structural features of colloidal species in the human fasted upper small intestine

      Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    148. Published

      Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

      Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    149. Published

      Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

      Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    150. Published

      Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

      Sassene, P. J., Mosgaard, M. D., Löbmann, K., Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    151. Published

      Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

      Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    152. Published

      Marine lipids and the bioavailability of omega-3 fatty acids

      Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

      Research output: Contribution to journalReviewResearchpeer-review

    153. 2014
    154. Published

      Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

      Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    155. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    156. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    157. Published

      Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

      Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    158. Published

      In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

      Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    159. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    160. Published

      In vitro models for the prediction of in vivo performance of oral dosage forms

      Kostewicz, E. S., Abrahamsson, B., Brewster, M., Brouwers, J., Butler, J., Carlert, S., Dickinson, P. A., Dressman, J., Holm, R., Klein, S., Mann, J., McAllister, M., Minekus, M., Muenster, U., Mullertz, Anette , Verwei, M., Vertzoni, M., Weitschies, W. & Augustijns, P., 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 342-66 25 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    161. Published

      A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

      Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    162. Published

      Refining stability and dissolution rate of amorphous drug formulations

      Grohganz, Holger, Priemel, P. A., Löbmann, K., Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    163. Published

      Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    164. Published

      In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

      Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549

      Research output: Contribution to journalJournal articleResearchpeer-review

    165. Published

      Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

      Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    166. Published

      Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

      Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8

      Research output: Contribution to journalJournal articleResearchpeer-review

    167. Published

      Miniaturized approach for excipient selection during the development of oral solid dosage form

      Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    168. Published

      Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract

      Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    169. Published

      Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

      Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

      Research output: Contribution to journalJournal articleResearchpeer-review

    170. Published

      Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation

      Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In: Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    171. Published

      Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

      Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    172. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journalJournal articleResearchpeer-review

    173. Published

      Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

      Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239

      Research output: Contribution to journalJournal articleResearchpeer-review

    174. Published

      Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium

      Borkar, N. N., Xia, D., Holm, R., Gan, Y., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 204-10 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    175. Published

      Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

      Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    176. 2013
    177. Published

      Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

      Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    178. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & LFCS Consortium, L. C., Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3059-76 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    179. Published

      Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

      Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    180. Published

      Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

      Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    181. Published

      Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats

      Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    182. Published

      Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy

      Mullertz, Anette , Fatouros, D. G., Vertzoni, M. & Reppas, C., Oct 2013, In: The Journal of pharmacy and pharmacology. 65, 10, p. 1482-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    183. Published

      Bile salts and their importance for drug absorption

      Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    184. Published

      Lipid-based formulations for oral administration of poorly water-soluble drugs

      Mu, Huiling, Holm, R. & Mullertz, Anette , 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 215-24 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    185. Published

      Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

      Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

      Research output: Contribution to journalJournal articleResearchpeer-review

    186. Published

      Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck, Fano, M. & Mullertz, Anette , Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2689-98 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    187. Published

      Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    188. Published

      Recent developments in oral lipid-based drug delivery

      Thomas, N., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 375-382 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    189. Published

      Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology

      Ren, S., Mu, Huiling, Alchaer, F., Chtatou, A. & Mullertz, Anette , May 2013, In: Drug Development and Industrial Pharmacy. 39, 5, p. 799-806 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    190. Published

      Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

      Research output: Contribution to conferencePosterResearchpeer-review

    191. Published

      A new approach to dissolution testing by UV imaging and finite element simulations

      Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

      Research output: Contribution to journalJournal articleResearchpeer-review

    192. Published

      Development and rheological profiling of biosimilar mucus

      Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

      Research output: Contribution to journalConference articleResearchpeer-review

    193. Published

      Mucosal drug delivery: barriers, in vitro models and formulation strategies

      Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

      Research output: Contribution to journalReviewResearchpeer-review

    194. Published

      Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation

      Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    195. Published

      Polymer selection for simulation of rheological properties of human gastric fluid

      Pedersen, P. B., Vilmann, P., Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 241-247

      Research output: Contribution to journalConference articleResearch

    196. Published

      Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

      Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    197. Published

      Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug Simvastatin in dogs

      Thomas, N., Holm, R., Garmer, M., Karlsson, J. J., Mullertz, Anette & Rades, Thomas, 2013, In: A A P S Journal. 15, 1, p. 219-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    198. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    199. 2012
    200. Published

      Characterising lipid lipolysis and its implication in lipid-based formulation development

      Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In: The AAPS journal. 14, 4, p. 860-71 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    201. Published

      Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

      Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In: International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    202. Published

      In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

      Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: International Journal of Pharmaceutics. 441, 1-2, p. 323-333

      Research output: Contribution to journalJournal articleResearchpeer-review

    203. Published

      Influence of bile on the absorption of halofantrine from lipid-based formulations

      Holm, R., Tønsberg, H., Jørgensen, E. B., Abedinpour, P., Farsad, S. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 281-287

      Research output: Contribution to journalJournal articleResearchpeer-review

    204. Published

      Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems

      Thomas, N., Mullertz, Anette , Graf, A. & Rades, T., 2012, In: Journal of Pharmaceutical Sciences. 101, 5, p. 1721-1731

      Research output: Contribution to journalJournal articleResearchpeer-review

    205. Published

      Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

      Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In: Molecular Pharmaceutics. 9, 2, p. 237-247

      Research output: Contribution to journalJournal articleResearchpeer-review

    206. Published

      Oral delivery of peptides and proteins using lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , 2012, In: Expert Opinion on Drug Delivery. 9, 10, p. 1289-304 16 p.

      Research output: Contribution to journalReviewResearchpeer-review

    207. Published

      SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

      Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

      Research output: Contribution to journalJournal articleResearchpeer-review

    208. Published

      Spatial confinement can lead to increased stability of amorphous indomethacin

      Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    209. Published

      Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

      Williams, H. D., Anby, M. U., Sassene, P., Kleberg, K., Bakala-N’Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Pouton, C. W. & Porter, C. J. H., 2012, In: Molecular Pharmaceutics. 9, 11, p. 3286-3300 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    210. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations

      Williams, H. D., Sassene, P., Kleberg, K., Bakala-N'Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: Journal of Pharmaceutical Sciences. 101, 9, p. 3360-3380

      Research output: Contribution to journalJournal articleResearchpeer-review

    211. Published

      Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

      Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

      Research output: Contribution to journalJournal articleResearchpeer-review

    212. 2011
    213. Published

      A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

      Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

      Research output: Contribution to journalJournal articleResearchpeer-review

    214. Published

      Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

      Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

      Research output: Contribution to journalJournal articleResearchpeer-review

    215. Published

      In vitro lipolysis models as a tool for the characterization of oral lilpid and surfactant based drug delivery systems

      Larsen, A. T., Sassene, P. & Mullertz, Anette , 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 245-255

      Research output: Contribution to journalJournal articleResearchpeer-review

    216. Published

      Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

      Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    217. Published

      Phase transformations of amlodipine besylate solid forms

      Koradia, V. S., Lemos, A. F. F. D., Allesø, M., Diego, H. L. D., Ringkjøbing-Elema, M., Mullertz, Anette & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7, p. 2896-2910

      Research output: Contribution to journalJournal articleResearchpeer-review

    218. 2010
    219. Published

      Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

      Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

      Research output: Contribution to conferencePosterResearch

    220. Published

      Insights into the ultrastructure of human intestinal fluids in the fed state by electron microscopy analysis

      Mullertz, Anette , Fatouros, D., Smith, J. R., Vertzoni, M. & Rappas, C., Nov 2010.

      Research output: Contribution to conferencePosterResearch

    221. Published

      Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

      Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

      Research output: Contribution to conferencePosterResearch

    222. Published

      Selection of a lipase for development of an in vitro gastric lipid digestion model

      Larsen, A. T., Jensen, L. G., Hansen, K. K. & Mullertz, Anette , Nov 2010.

      Research output: Contribution to conferencePosterResearch

    223. Published

      Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

      Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

      Research output: Contribution to journalJournal articleResearchpeer-review

    224. Published

      An updated and simplified method for bile duct cannulation of rats

      Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376

      Research output: Contribution to journalJournal articleResearchpeer-review

    225. Published

      Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

      Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    226. Published

      Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

      Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    227. Published

      Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit

      Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In: The AAPS Journal. 12, 3, p. 465-472

      Research output: Contribution to journalReviewResearch

    228. Published

      New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

      Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    229. Published

      Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

      Sassene, P. J., Knopp, M. M., Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

      Research output: Contribution to journalJournal articleResearchpeer-review

    230. 2009
    231. Published

      Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties

      Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116

      Research output: Contribution to journalJournal articleResearchpeer-review

    232. Published

      Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374

      Research output: Contribution to journalJournal articleResearchpeer-review

    233. Published

      Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

      Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    234. Published

      Influence of the solid form of siramesine hydrochloride on its behaviour in aqueous environments

      Zimmermann, A., Tian, F., Lopez de Diego, H., Ringkjøbing Elema, M., Rantanen, Jukka, Mullertz, Anette & Hovgaard, L., 2009, In: Pharmaceutical Research. 26, 4, p. 846-854

      Research output: Contribution to journalJournal articleResearchpeer-review

    235. Published

      Optimization of the in vitro lipolysis rate of SMEDDS containing cinnarizine

      Ulmann, C., Figueriedo-Larsen, M., Refsgaard, L., Hellekilde, J., Larsen, A., Nielsen, C., Olesen, P. & Mullertz, Anette , 2009.

      Research output: Contribution to conferencePosterResearch

    236. Published

      Physicochemical characterization of simulated intestinal fed-state fluids containing lyso-phosphatidylcholine and cholesterol

      Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Dissolution Technologies. 16, 3, p. 47-50

      Research output: Contribution to journalJournal articleResearchpeer-review

    237. Published

      Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6 3 p.

      Research output: Contribution to journalJournal articleResearch

    238. Published

      Tabletter med løse ender

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journalJournal articleResearch

    239. Published

      The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

      Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

      Research output: Contribution to conferencePosterResearch

    240. 2008
    241. Published

      In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability

      Fatouros, D. & Mullertz, Anette , 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76

      Research output: Contribution to journalReviewResearch

    242. Published

      Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state

      Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562

      Research output: Contribution to journalJournal articleResearchpeer-review

    243. Published

      Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30

      Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In: Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    244. Published

      Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

      Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

      Research output: Contribution to conferencePosterResearch

    245. Published

      Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

      Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

      Research output: Contribution to journalJournal articleResearchpeer-review

    246. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33

      Research output: Contribution to journalJournal articleResearch

    247. Published

      In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks

      Fatouros, D. G., Nielsen, F. S., Douroumis, D., Hadjileontiadis, L. J. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 3, p. 887-898

      Research output: Contribution to journalJournal articleResearchpeer-review

    248. Published

      Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

      Research output: Contribution to journalJournal articleResearchpeer-review

    249. Published

      Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis

      Larsen, A., Holm, R., Pedersen, M. L. & Mullertz, Anette , 2008, In: Pharmaceutical Research. 25, 12, p. 2769-2777

      Research output: Contribution to journalJournal articleResearchpeer-review

    250. Published

      Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

      Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657

      Research output: Contribution to journalJournal articleResearchpeer-review

    251. 2007
    252. Published

      Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

      Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

      Research output: Contribution to journalJournal articleResearchpeer-review

    253. Published

      Biorelevant dissolution media

      Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    254. Published

      Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds

      Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In: Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    255. Published

      Clinical studies with oral lipid based formulations of poorly soluble compounds

      Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    256. Published

      Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

      Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In: Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

      Research output: Contribution to journalJournal articleResearchpeer-review

    257. Published

      Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

      Research output: Contribution to journalJournal articleResearchpeer-review

    258. Published

      Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound

      Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.

      Research output: Contribution to conferencePosterResearch

    259. Published

      Liquid self-microemulsifying drug delivery

      Mullertz, Anette & Grove, M., 2007, Oral lipid-based formulations: enhancing the bioavailability of poor water-soluble drugs. Hauss, D. J. (ed.). New York: Informa Healthcare, p. 107-128

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    260. Published

      Morphological observations on a lipid-based drug delivery system during in vitro digestion

      Fatouros, D. G., Bergenstahl, B. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 31, 2, p. 85-94

      Research output: Contribution to journalJournal articleResearchpeer-review

    261. Published

      Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering

      Fatouros, D. G., Deen, R., Arleth, Lise, Bergenstahl, B., Nielsen, F. S., Pedersen, J. S. & Mullertz, Anette , 2007, In: Pharmaceutical Research. 24, 10, p. 1844-1853 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    262. Published

      Using in vitro dynamic lipolysis modeling as a tool for exploring IVIVC relationships for oral lipid-based formulations

      Mullertz, Anette & Fatourus, D. G., 2007, Oral lipid-based formulations: enhancing the bioviabillity of poorly water-soluble drugs. Hauss, D. J. (ed.). New York: Informa healtcare, p. 257-272

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    263. 2006
    264. Published

      Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

      Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    265. Published

      Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

      Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    266. Published

      Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

      Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    267. Published

      Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols

      Holm, R., Porsgaard, T., Porter, H., Høy, C., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2006, In: European Journal of Lipid Science and Technology. 108, 9, p. 714-722 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    268. 2005
    269. Published

      Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

      Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    270. Published

      Development of  in vitro methods for the evaluation of formulation performance

      Mullertz, Anette & Nielsen, F. S., 2005. 12 p.

      Research output: Contribution to conferencePaperResearchpeer-review

    271. Published

      Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug

      Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    272. Published

      Enzymatic characterization of lipid-based drug delivery systems

      Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    273. Published

      In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media

      Sunesen, V. H., Pedersen, B. L., Kristensen, H. G. & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 305-13 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    274. 2004
    275. Published

      Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats

      Karpf, D. M., Holm, R., Kristensen, H. G. & Mullertz, Anette , 2004, In: Pharmaceutical Research. 21, 8, p. 1413-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    276. Published

      Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols

      Christensen, J. Ø., Schultz, K., Mollgaard, B., Kristensen, H. G. & Mullertz, Anette , 2004, In: European Journal of Pharmaceutical Sciences. 23, 3, p. 287-96 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    277. 2003
    278. Published

      Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides

      Holm, R., Porter, C. J. H., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2003, In: European Journal of Pharmaceutical Sciences. 20, 1, p. 91-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    279. 2002
    280. Published

      Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

      Holm, R., Porter, C. J. H., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2002, In: Pharmaceutical Research. 19, 9, p. 1354-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 1302503