Anette Müllertz

Anette Müllertz

Professor


  1. 2017
  2. Published

    In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

    Tran, T., Siqueira Jørgensen, Scheyla Daniela, Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In : Journal of Controlled Release. 255, p. 45-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

    Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In : Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

    Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In : Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

    Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In : International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

    Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In : Biomacromolecules. 18, 4, p. 1401-1410 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

    Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In : Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

    Siqueira Jørgensen, Scheyla Daniela, Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In : A A P S Journal. 19, 2, p. 587-594 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

    Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In : The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

    Kamstrup, D., Berthelsen, Ragna, Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In : A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

    Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In : Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

    Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In : Molecular Pharmaceutics. 14, 12, p. 4154-4160

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

    Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In : PLOS ONE. 12, 11, 18 p., e0188848.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2016
  15. Published

    Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

    Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, Korbinian, 12 Nov 2016, In : Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

    Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In : Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

    Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In : Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Development of a μDissolution-Permeation model with in situ drug concentration monitoring

    Berthelsen, Ragna, Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saabye, L., Madelung, P. & Mullertz, Anette , 1 Oct 2016, In : Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

    Palmelund, Henrik Brogaard, Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In : Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

    Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In : International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

    Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In : Food & Function. 7, 9, p. 3989-3998 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

    Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In : International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs

    Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

    Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In : European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

    Borkar, N., Chen, Z., Saaby, L., Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In : International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Polymeric microcontainers improve oral bioavailability of furosemide

    Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In : International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

    Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In : International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

    Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Dissolution Model Development: Formulation Effects and Filter Complications

    Berthelsen, Ragna, Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In : Dissolution Technologies. 23, 1, p. 6-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

    Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In : The A A P S Journal. 18, 1, p. 180-186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

    Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In : European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Evaluating Oral Drug Delivery Systems: Digestion Models.

    Berthelsen, Ragna, Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published

    Evaluating Oral Drug Delivery Systems: Dissolution Models.

    Berthelsen, Ragna, Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  35. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release

    Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In : P L o S One. 11, 12, 13 p., e0168050.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

    Klindt-Toldam, S., Larsen, S. K., Saaby, L., Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knøchel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In : Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2015
  38. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

    Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

    Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

    Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    pH-triggered drug release from biodegradable microwells for oral drug delivery

    Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In : Biomedical Microdevices. 17, 7 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

    Berthelsen, Ragna, Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In : Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structural features of colloidal species in the human fasted upper small intestine

    Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In : Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

    Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In : Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

    Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In : Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

    Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In : Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

    Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Marine lipids and the bioavailability of omega-3 fatty acids

    Mu, Huiling & Mullertz, Anette , 2015, In : Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. 2014
  50. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

    Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

    Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In : Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

    Berthelsen, Ragna, Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In : International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

    Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In : A A P S Journal. 16, 4, p. 875-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

    Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In : The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302503