Anette Müllertz
Professor
- 2002
- Published
Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats
Holm, R., Porter, C. J. H., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2002, In: Pharmaceutical Research. 19, 9, p. 1354-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides
Holm, R., Porter, C. J. H., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2003, In: European Journal of Pharmaceutical Sciences. 20, 1, p. 91-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats
Karpf, D. M., Holm, R., Kristensen, H. G. & Mullertz, Anette , 2004, In: Pharmaceutical Research. 21, 8, p. 1413-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols
Christensen, J. Ø., Schultz, K., Mollgaard, B., Kristensen, H. G. & Mullertz, Anette , 2004, In: European Journal of Pharmaceutical Sciences. 23, 3, p. 287-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides
Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of in vitro methods for the evaluation of formulation performance
Mullertz, Anette & Nielsen, F. S., 2005. 12 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug
Sunesen, V. H., Vedelsdal, R., Kristensen, H. G., Christrup, Lona Louring & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 297-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enzymatic characterization of lipid-based drug delivery systems
Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media
Sunesen, V. H., Pedersen, B. L., Kristensen, H. G. & Mullertz, Anette , 2005, In: European Journal of Pharmaceutical Sciences. 24, 4, p. 305-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats
Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol
Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture
Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols
Holm, R., Porsgaard, T., Porter, H., Høy, C., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2006, In: European Journal of Lipid Science and Technology. 108, 9, p. 714-722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state
Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant dissolution media
Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds
Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In: Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical studies with oral lipid based formulations of poorly soluble compounds
Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection
Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In: Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms
Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21Research output: Contribution to journal › Journal article › Communication
- Published
Effect of labrafil 2125CS on the oral bioavailability of danazol, a poorly soluble drug compound
Larsen, A., Holm, R., Pedersen, M. & Mullertz, Anette , 2007.Research output: Contribution to conference › Poster › Research
- Published
Liquid self-microemulsifying drug delivery
Mullertz, Anette & Grove, M., 2007, Oral lipid-based formulations: enhancing the bioavailability of poor water-soluble drugs. Hauss, D. J. (ed.). New York: Informa Healthcare, p. 107-128Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Morphological observations on a lipid-based drug delivery system during in vitro digestion
Fatouros, D. G., Bergenstahl, B. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 31, 2, p. 85-94Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering
Fatouros, D. G., Deen, R., Arleth, Lise, Bergenstahl, B., Nielsen, F. S., Pedersen, J. S. & Mullertz, Anette , 2007, In: Pharmaceutical Research. 24, 10, p. 1844-1853 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using in vitro dynamic lipolysis modeling as a tool for exploring IVIVC relationships for oral lipid-based formulations
Mullertz, Anette & Fatourus, D. G., 2007, Oral lipid-based formulations: enhancing the bioviabillity of poorly water-soluble drugs. Hauss, D. J. (ed.). New York: Informa healtcare, p. 257-272Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2008
- Published
In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability
Fatouros, D. & Mullertz, Anette , 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76Research output: Contribution to journal › Review › Research
- Published
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state
Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30
Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In: Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products
Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.Research output: Contribution to conference › Poster › Research
- Published
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33Research output: Contribution to journal › Journal article › Research
- Published
In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks
Fatouros, D. G., Nielsen, F. S., Douroumis, D., Hadjileontiadis, L. J. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 3, p. 887-898Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80
Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis
Larsen, A., Holm, R., Pedersen, M. L. & Mullertz, Anette , 2008, In: Pharmaceutical Research. 25, 12, p. 2769-2777Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound
Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties
Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products
Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats
Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of the solid form of siramesine hydrochloride on its behaviour in aqueous environments
Zimmermann, A., Tian, F., Lopez de Diego, H., Ringkjøbing Elema, M., Rantanen, Jukka, Mullertz, Anette & Hovgaard, L., 2009, In: Pharmaceutical Research. 26, 4, p. 846-854Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization of the in vitro lipolysis rate of SMEDDS containing cinnarizine
Ulmann, C., Figueriedo-Larsen, M., Refsgaard, L., Hellekilde, J., Larsen, A., Nielsen, C., Olesen, P. & Mullertz, Anette , 2009.Research output: Contribution to conference › Poster › Research
- Published
Physicochemical characterization of simulated intestinal fed-state fluids containing lyso-phosphatidylcholine and cholesterol
Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Dissolution Technologies. 16, 3, p. 47-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof
Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
- Published
Tabletter med løse ender
Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6Research output: Contribution to journal › Journal article › Research
- Published
The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment
Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.Research output: Contribution to conference › Poster › Research
- 2010
- Published
An updated and simplified method for bile duct cannulation of rats
Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity
Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies
Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit
Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In: The AAPS Journal. 12, 3, p. 465-472Research output: Contribution to journal › Review › Research
- Published
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate
Sassene, P. J., Knopp, Matthias Manne, Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302503
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Research output: Contribution to journal › Journal article › Research › peer-review
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306
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Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › Research › peer-review
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