Anette Müllertz

Anette Müllertz

Professor


  1. Published

    The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

    Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

    Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

    Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

    Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

    Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

    Holm, R., Porter, C. J. H., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2002, In: Pharmaceutical Research. 19, 9, p. 1354-61 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Bile salts and their importance for drug absorption

    Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols

    Holm, R., Porsgaard, T., Porter, H., Høy, C., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2006, In: European Journal of Lipid Science and Technology. 108, 9, p. 714-722 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides

    Holm, R., Porter, C. J. H., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2003, In: European Journal of Pharmaceutical Sciences. 20, 1, p. 91-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Influence of bile on the absorption of halofantrine from lipid-based formulations

    Holm, R., Tønsberg, H., Jørgensen, E. B., Abedinpour, P., Farsad, S. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 281-287

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

    Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

    Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

    Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Ramakrishnan, Venkatasubramanian, Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

    Heerup, Christine Kopka, Ebbesen, M. F., Geng, X., Madsen, Sofie Falkenløve, Berthelsen, Ragna & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

    Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

    Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

    Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

    Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Refining stability and dissolution rate of amorphous drug formulations

    Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

    Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Towards analyzing the potential of exosomes to deliver microRNA therapeutics

    Giassafaki, L. N., Siqueira, S., Panteris, E., Psatha, K., Chatzopoulou, F., Aivaliotis, M., Tzimagiorgis, G., Mullertz, Anette , Fatouros, D. G. & Vizirianakis, I. S., 2021, In: Journal of Cellular Physiology. 236, 2, p. 1529-1544 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

    Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Colloid structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatourus, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2008.

    Research output: Contribution to conferencePosterResearch

  27. Published

    In vitro-in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks

    Fatouros, D. G., Nielsen, F. S., Douroumis, D., Hadjileontiadis, L. J. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 3, p. 887-898

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering

    Fatouros, D. G., Deen, R., Arleth, Lise, Bergenstahl, B., Nielsen, F. S., Pedersen, J. S. & Mullertz, Anette , 2007, In: Pharmaceutical Research. 24, 10, p. 1844-1853 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Morphological observations on a lipid-based drug delivery system during in vitro digestion

    Fatouros, D. G., Bergenstahl, B. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 31, 2, p. 85-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Clinical studies with oral lipid based formulations of poorly soluble compounds

    Fatouros, D., Karpf, D. M., Nielsen, Flemming Steen & Mullertz, Anette , 2007, In: Therapeutics and Clinical Risk Management. 3, 4, p. 591-604 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    In vitro lipid digestion models in design of drug delivery systems for enhancing oral bioavailability

    Fatouros, D. & Mullertz, Anette , 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 1, p. 65-76

    Research output: Contribution to journalReviewResearch

  32. Published

    Physicochemical characterization of simulated intestinal fed-state fluids containing lyso-phosphatidylcholine and cholesterol

    Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Dissolution Technologies. 16, 3, p. 47-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

    Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21

    Research output: Contribution to journalJournal articleCommunication

  35. Published

    Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model

    Falavigna, M., Klitgaard, Mette, Berthelsen, Ragna, Mullertz, Anette & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

    Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  37. Published

    Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

    Eliasen, J. N., Berthelsen, Ragna, Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

    Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

    Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

    Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: International Journal of Pharmaceutics. 441, 1-2, p. 323-333

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

    Dalskov Mosgaard, M., Strindberg, Sophie , Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

    Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

    Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

    Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

    Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

    Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  47. Published

    Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

    Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

    Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

    Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery

    Christfort, J. F., Strindberg, Sophie , Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302503