Anette Müllertz

Anette Müllertz

Professor


  1. Published

    Towards the understanding of complex fluids in pharmaceutical sciences

    Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In : Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

    Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Polymer selection for simulation of rheological properties of human gastric fluid

    Pedersen, P. B., Vilmann, P., Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S. G., 2013, In : Nordic Rheology Society Annual Transactions. 21, p. 241-247

    Research output: Contribution to journalConference articleResearch

  4. Published

    Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

    Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In : Biomacromolecules. 18, 4, p. 1401-1410 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

    Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In : International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

    Palmelund, Henrik Brogaard, Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In : Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

    Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

    Research output: Contribution to conferencePosterResearch

  8. Published

    Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats

    Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In : European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

    Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In : Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Spatial confinement can lead to increased stability of amorphous indomethacin

    Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In : European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

    Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

    Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In : Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    pH-triggered drug release from biodegradable microwells for oral drug delivery

    Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In : Biomedical Microdevices. 17, 7 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

    Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In : International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Polymeric microcontainers improve oral bioavailability of furosemide

    Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In : International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state

    Nielsen, F. S., Petersen, K. & Mullertz, Anette , 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 553-562

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds

    Nielsen, F. S., Gibault, E., Ljusberg-Wahren, H., Arleth, Lise, Pedersen, J. S. & Mullertz, Anette , 2007, In : Journal of Pharmaceutical Sciences. 96, 4, p. 876-892 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof

    Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, Janne & Bar-Shalom, Daniel, 2009, In : Lægemiddelforskning. p. 4-6 3 p.

    Research output: Contribution to journalJournal articleResearch

  19. Published

    Tabletter med løse ender

    Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, Janne & Bar-Shalom, Daniel, 2009, In : Lægemiddelforskning. p. 4-6

    Research output: Contribution to journalJournal articleResearch

  20. Published

    Using in vitro dynamic lipolysis modeling as a tool for exploring IVIVC relationships for oral lipid-based formulations

    Mullertz, Anette & Fatourus, D. G., 2007, Oral lipid-based formulations: enhancing the bioviabillity of poorly water-soluble drugs. Hauss, D. J. (ed.). New York: Informa healtcare, p. 257-272

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Liquid self-microemulsifying drug delivery

    Mullertz, Anette & Grove, M., 2007, Oral lipid-based formulations: enhancing the bioavailability of poor water-soluble drugs. Hauss, D. J. (ed.). New York: Informa Healthcare, p. 107-128

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  22. Published

    Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy

    Mullertz, Anette , Fatouros, D. G., Vertzoni, M. & Reppas, C., Oct 2013, In : The Journal of pharmacy and pharmacology. 65, 10, p. 1482-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Development of  in vitro methods for the evaluation of formulation performance

    Mullertz, Anette & Nielsen, F. S., 2005. 12 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  24. Published

    Insights into the ultrastructure of human intestinal fluids in the fed state by electron microscopy analysis

    Mullertz, Anette , Fatouros, D., Smith, J. R., Vertzoni, M. & Rappas, C., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  25. Published

    New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

    Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In : Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Biorelevant dissolution media

    Mullertz, Anette , 2007, Solvent systems and their selection in pharmaceutics and biopharmaceutics: Biotechnology: Pharmaceutical aspects. Augustijns, P. & Brewster, M. E. (eds.). New York: Springer Science+Business Media, Vol. 6. p. 107-177

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  27. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

    Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In : Molecular Pharmaceutics. 9, 2, p. 237-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Structural features of colloidal species in the human fasted upper small intestine

    Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In : Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Lipid-based formulations for oral administration of poorly water-soluble drugs

    Mu, Huiling, Holm, R. & Mullertz, Anette , 30 Aug 2013, In : International Journal of Pharmaceutics. 453, 1, p. 215-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Marine lipids and the bioavailability of omega-3 fatty acids

    Mu, Huiling & Mullertz, Anette , 2015, In : Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

    Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In : Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

    Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

    Michaelsen, M. H., Siqueira Jørgensen, Scheyla Daniela, Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

    Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In : The A A P S Journal. 18, 1, p. 180-186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

    Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

    Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In : Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

    Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In : Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

    Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In : International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Polymeric Lids for Microcontainers for Oral Protein Delivery

    Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, Jacob Rune, Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In : Macromolecular Bioscience. 19, 5, 1900004.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    From concept to in vivo testing: Microcontainers for oral drug delivery

    Mazzoni, C., Tentor, F., Strindberg, Sophie , Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 343-351 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

    Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In : Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation

    Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In : Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

    Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In : European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

    Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In : European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

    Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In : Journal of Drug Delivery Science and Technology. 39, p. 516-522

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

    Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In : International Journal of Pharmaceutics. 467, 1-2, p. 1-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

    Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In : Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

    López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, L., Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., 2018, In : Food Hydrocolloids. 79, p. 117-126 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

    Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Enzymatic characterization of lipid-based drug delivery systems

    Ljusberg-Wahren, H., Seier Nielsen, F., Brogård, M., Troedsson, E. & Mullertz, Anette , 2005, In : Internation Journal of Pharmaceutics. 298, 2, p. 328-32 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302503