Anette Müllertz

Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

Research output: Contribution to journal › Journal article › Research › peer-review

Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus

Klitgaard, Mette, Jacobsen, Jette, Kristensen, M. N., Berthelsen, R. & Mullertz, Anette , 2024, (Accepted/In press) In: Drug Delivery and Translational Research.

Research output: Contribution to journal › Journal article › Research › peer-review

Development and in vitro evaluation of an infant friendly self-nanoemulsifying drug delivery system (SNEDDS) loaded with an amphotericin B-monoacyl phosphatidylcholine complex for oral delivery

Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2024, In: International Journal of Pharmaceutics. 660, 8 p., 124286.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

Research output: Contribution to journal › Journal article › Research › peer-review

Binder jetting 3D printing in fabricating pharmaceutical solid products for precision medicine

Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2024, In: Basic & clinical pharmacology & toxicology. 134, 3, p. 325-332

Research output: Contribution to journal › Review › Research › peer-review

Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, Thomas, Mullertz, Anette & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.

Research output: Contribution to journal › Journal article › Research › peer-review

Chitosan Alginate Nanoparticles of Protein Hydrolysate from Acheta domesticus with Enhanced Stability for Skin Delivery

Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Juntrapirom, S., Kanjanakawinkul, W., Mullertz, Anette , Rades, Thomas & Chaiyana, W., 2024, In: Pharmaceutics. 16, 6, 25 p., 724.

Research output: Contribution to journal › Journal article › Research › peer-review

Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

Research output: Contribution to journal › Journal article › Research › peer-review

Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

Research output: Contribution to journal › Journal article › Research › peer-review

Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

Research output: Contribution to journal › Journal article › Research › peer-review

Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex

Liu, X., Berthelsen, R., Bar-Shalom, Daniel, Kjellerup Lind, T., Doutch, J. & Mullertz, Anette , 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.

Research output: Contribution to journal › Journal article › Research › peer-review

Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)

Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207

Research output: Contribution to journal › Journal article › Research › peer-review

The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

Møller, Amalie Lykkemark, Schultz, H. B., Meola, T. R., Joyce, P., Mullertz, Anette & Prestidge, C. A., 2023, In: Pharmaceutics. 15, 1, 14 p., 284.

Research output: Contribution to journal › Journal article › Research › peer-review

Drug Dissolution in Oral Drug Absorption: Workshop Report

Raines, K., Agarwal, P., Augustijns, P., Alayoubi, A., Attia, L., Bauer-Brandl, A., Brandl, M., Chatterjee, P., Chen, H., Yu, Y. C., Coutant, C., Coutinho, A. L., Curran, D., Dressman, J., Ericksen, B., Falade, L., Gao, Y., Gao, Z., Ghosh, D., Ghosh, T. & 26 others, Govada, A., Gray, E., Guo, R., Hammell, D., Hermans, A., Jaini, R., Li, H., Mandula, H., Men, S., Milsmann, J., Moldthan, H., Moody, R., Moseson, D. E., Mullertz, Anette , Patel, R., Paudel, K., Reppas, C., Savkur, R., Schaefer, K., Serajuddin, A., Taylor, L. S., Valapil, R., Wei, K., Weitschies, W., Yamashita, S. & Polli, J. E., 2023, In: AAPS Journal. 25, 6, 20 p., 103.

Research output: Contribution to journal › Journal article › Research › peer-review

Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis

Serioli, L., Gruzinskyte, L., Zappalà, G., Hwu, E. T., Laksafoss, T. Z., Jensen, P. L., Demarchi, D., Mullertz, Anette , Boisen, A. & Zór, K., 2023, In: Lab on a Chip. 23, p. 1603-1612

Research output: Contribution to journal › Journal article › Research › peer-review

Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

Research output: Contribution to journal › Journal article › Research › peer-review

Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

Research output: Contribution to journal › Journal article › Research › peer-review

Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

Research output: Contribution to journal › Journal article › Research › peer-review

Formulation, characterization and in-vitro evaluation of self-nanoemulsifying drug delivery system containing rhamnolipid biosurfactant

Khan, Muhammad Ayub, Ullah, K., Rahman, N. U., Mahmood, A., Mullertz, Anette , Mannan, A., Murtaza, G. & Khan, S. A., 2022, In: Journal of Drug Delivery Science and Technology. 75, 9 p., 103673.

Research output: Contribution to journal › Journal article › Research › peer-review

Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

Research output: Contribution to journal › Journal article › Research › peer-review

The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats

Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.

Research output: Contribution to journal › Journal article › Research › peer-review

Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

Research output: Contribution to journal › Journal article › Research › peer-review

Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

Research output: Contribution to journal › Journal article › Research › peer-review

UNGAP best practice for improving solubility data quality of orally administered drugs

Vertzoni, M., Alsenz, J., Augustijns, P., Bauer-Brandl, A., Bergström, C. A. S., Brouwers, J., Mullertz, Anette , Perlovich, G., Saal, C., Sugano, K. & Reppas, C., 1 Jan 2022, In: European Journal of Pharmaceutical Sciences. 168, 21 p., 106043.

Research output: Contribution to journal › Journal article › Research › peer-review

Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing

Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.

Research output: Contribution to journal › Review › Research › peer-review

Structured approach for designing drug-loaded solid products by binder jetting 3D printing

Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: European Journal of Pharmaceutical Sciences. 178, 11 p., 106280.

Research output: Contribution to journal › Journal article › Research › peer-review

Hot punching for loading of biodegradable microcontainers with budesonide-Soluplus film

Abid, Z., Andreoli, F., Kristensen, M. N., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2021, In: Biomedical Microdevices. 23, 11 p., 37.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploring Porcine Gastric and Intestinal Fluids using Microscopic and Solubility Estimates: Impact of Placebo Self-Emulsifying Drug Delivery System Administration to Inform Bio-Predictive in vitro Tools

Bennett-Lenane, H., Jørgensen, J. R., Koehl, N. J., Henze, L. J., O'Shea, J. P., Mullertz, Anette & Griffin, B. T., 2021, In: European Journal of Pharmaceutical Sciences. 161, 11 p., 105778.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery

Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.

Research output: Contribution to journal › Journal article › Research › peer-review

Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

Dahlgren, D., Venczel, M., Ridoux, J. P., Skjöld, C., Mullertz, Anette , Holm, R., Augustijns, P., Hellström, P. M. & Lennernäs, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 163, p. 240-251

Research output: Contribution to journal › Journal article › Research › peer-review

Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model

Falavigna, M., Klitgaard, Mette, Berthelsen, R., Mullertz, Anette & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Towards analyzing the potential of exosomes to deliver microRNA therapeutics

Giassafaki, L. N., Siqueira, S., Panteris, E., Psatha, K., Chatzopoulou, F., Aivaliotis, M., Tzimagiorgis, G., Mullertz, Anette , Fatouros, D. G. & Vizirianakis, I. S., 2021, In: Journal of Cellular Physiology. 236, 2, p. 1529-1544 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies

Grundy, M. M. L., Abrahamse, E., Almgren, A., Alminger, M., Andres, A., Ariëns, R. M. C., Bastiaan-Net, S., Bourlieu-Lacanal, C., Brodkorb, A., Bronze, M. R., Comi, I., Couëdelo, L., Dupont, D., Durand, A., El, S. N., Grauwet, T., Heerup, C., Heredia, A., Infantes Garcia, M. R., Jungnickel, C. & 26 others, Kłosowska-Chomiczewska, I. E., Létisse, M., Macierzanka, A., Mackie, A. R., McClements, D. J., Menard, O., Meynier, A., Michalski, M. C., Mulet-Cabero, A. I., Mullertz, Anette , Payeras Perelló, F. M., Peinado, I., Robert, M., Secouard, S., Serra, A. T., Silva, S. D., Thomassen, G., Tullberg, C., Undeland, I., Vaysse, C., Vegarud, G. E., Verkempinck, S. H. E., Viau, M., Zahir, M., Zhang, R. & Carrière, F., 2021, In: Journal of Functional Foods. 82, 104497.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

Research output: Contribution to journal › Journal article › Research › peer-review

Design of a self-unfolding delivery concept for oral administration of macromolecules

Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

Research output: Contribution to journal › Journal article › Research › peer-review

Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

Research output: Contribution to journal › Journal article › Research › peer-review

Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

Research output: Contribution to journal › Journal article › Research › peer-review

Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method

Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.

Research output: Contribution to journal › Journal article › Research › peer-review

Bovine Milk-Derived Emulsifiers Increase Triglyceride Absorption in Newborn Formula-Fed Pigs

Knudsen, K. B. K., Heerup, C., Jensen, T. R. S., Geng, X., Drachmann, N., Nordby, P., Jeppesen, Palle Bekker, Ifaoui, I., Mullertz, Anette , Sangild, Per Torp, Ostenfeld, M. S. & Thymann, Thomas, 2021, In: Nutrients. 13, 2, 15 p., 410.

Research output: Contribution to journal › Journal article › Research › peer-review

Drug solubilization during simulated pediatric gastro-intestinal digestion

Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.

Research output: Contribution to journal › Journal article › Research › peer-review

Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

Kubackova, J., Holas, O., Zbytovska, J., Vranikova, B., Zeng, G., Pavek, P. & Mullertz, Anette , Apr 2021, In: Pharmaceutics. 13, 4, 27 p., 459.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol

Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

Moller, A., Schultz, H. B., Meola, T. R., Mullertz, Anette & Prestidge, C. A., 2021, In: European Journal of Pharmaceutical Sciences. 157, 10 p., 105640.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

Research output: Contribution to journal › Journal article › Research › peer-review

Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197

Research output: Contribution to journal › Journal article › Research › peer-review

Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J. & 16 others, McAllister, M., Mullertz, Anette , O'Driscoll, C. M., Parrott, N., Paszkowska, J., Pavek, P., Porter, C. J. H., Reppas, C., Stillhart, C., Sugano, K., Toader, E., Valentova, K., Vertzoni, M., De Wildt, S. N., Wilson, C. G. & Augustijns, P., 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.

Research output: Contribution to journal › Review › Research › peer-review

Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

Abrahamsson, B., Mcallister, M., Augustijns, P., Zane, P., Butler, J., Holm, R., Langguth, P., Lindahl, A., Mullertz, Anette , Pepin, X., Rostami-hodjegan, A., Sjögren, E., Berntsson, M. & Lennernäs, H., 1 Jul 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 236-247 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.

Research output: Contribution to journal › Journal article › Research › peer-review

Milk osteopontin retains integrin-binding activity after in vitro gastrointestinal transit

Christensen, B., Karlsen, N. J., Jorgensen, S. D. S., Jacobsen, L. N., Ostenfeld, M. S., Petersen, S. V., Mullertz, Anette & Sorensen, E. S., Jan 2020, In: Journal of Dairy Science. 103, 1, p. 42-51

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384

Research output: Contribution to journal › Journal article › Research › peer-review

Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

Research output: Contribution to journal › Journal article › Research › peer-review

Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

Research output: Contribution to journal › Journal article › Research › peer-review

Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems

Klitgaard, Mette, Beilles, S., Sassene, P. J., Berthelsen, R. & Mullertz, Anette , 2020, In: Molecular Pharmaceutics. 17, 9, p. 3214-3222 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B

Kontogiannidou, E., Meikopoulos, T., Gika, H., Panteris, E., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., 2020, In: Pharmaceutics. 12, 8, 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Towards the development of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) containing trimethyl chitosan for the oral delivery of amphotericin B: In vitro assessment and cytocompatibility studies

Kontogiannidou, E., Meikopoulos, T., Virgiliou, C., Bouropoulos, N., Gika, H., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., Apr 2020, In: Journal of Drug Delivery Science and Technology. 56, 9 p., 101524.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of self -emulsifying drug delivery systems for oral insulin delivery using an in vitro model simulating the intestinal proteolysis

Liu, J., Hirschberg, C., Fano, M., Mu, Huiling & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents

Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.

Research output: Contribution to journal › Journal article › Research › peer-review

Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparison of induction methods for supersaturation: pH shift versus solvent shift

Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

Research output: Contribution to journal › Journal article › Research › peer-review

Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products [incl, correction]

Selen, A., Mullertz, Anette , Kesisoglou, F., Ho, R. J. Y., Cook, J. A., Dickinson, P. A. & Flanagan, T., 2020, In: AAPS Journal. 22, 5, 20 p., 97.

Research output: Contribution to journal › Journal article › Research › peer-review

Poorly soluble drugs

Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

Research output: Contribution to journal › Editorial › Research

Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

Stillhart, C., Vucicevic, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljus, G., Mooij, M. G., Parrott, N., Ungell, A. -., de Wildt, S. N., Orlu, M., Klein, S. & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 28 p., 105280.

Research output: Contribution to journal › Review › Research › peer-review

Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

Research output: Contribution to journal › Journal article › Research › peer-review

Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

Research output: Contribution to journal › Journal article › Research › peer-review

Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

Research output: Contribution to journal › Journal article › Research › peer-review

Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

Research output: Contribution to journal › Journal article › Research › peer-review

Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

Research output: Contribution to journal › Review › Research › peer-review

Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

Research output: Contribution to journal › Editorial › Research › peer-review

In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

Research output: Contribution to journal › Review › Research › peer-review

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, A., Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W. & 2 others, Reppas, C. & Augustijns, P., Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83

Research output: Contribution to journal › Journal article › Research › peer-review

Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

Research output: Contribution to journal › Letter › Research › peer-review

SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

Research output: Contribution to journal › Journal article › Research › peer-review

Polymeric Lids for Microcontainers for Oral Protein Delivery

Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

Research output: Contribution to journal › Journal article › Research › peer-review

Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development

Zane, P., Gieschen, H., Kersten, E., Mathias, N., Ollier, C., Johansson, P., Van den Bergh, A., Van Hemelryck, S., Reichel, A., Rotgeri, A., Schäfer, K., Mullertz, Anette & Langguth, P., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 222-231 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

Research output: Contribution to journal › Journal article › Research › peer-review

A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

Duraipandian, S., Knopp, Matthias Manne, Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

Research output: Contribution to journal › Journal article › Research › peer-review

Characterization of the hydrodynamics in a miniaturized dissolution apparatus

Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

Research output: Contribution to journal › Journal article › Research › peer-review

Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)

Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184

Research output: Contribution to journal › Journal article › Research › peer-review

Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

López-Barón , N., Sagnelli, D., Blennow, A., Holse, M., Gao, J., Saaby, Lasse, Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., Jun 2018, In: Food Hydrocolloids. 79, p. 117-126 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor^® RH40 using experimental design

Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545

Research output: Contribution to journal › Journal article › Research › peer-review

Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

Research output: Contribution to journal › Journal article › Research › peer-review

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

Research output: Contribution to journal › Journal article › Research › peer-review

Are phytosomes a superior nanodelivery system for the antioxidant rutin?

Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model

Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC

Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160

Research output: Contribution to journal › Journal article › Research › peer-review

Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

Research output: Contribution to journal › Journal article › Research › peer-review

Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

Research output: Contribution to journal › Journal article › Research › peer-review

Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

From concept to in vivo testing: Microcontainers for oral drug delivery

Mazzoni, C., Tentor, F., Strindberg, S. A., Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In: Journal of Controlled Release. 268, p. 343-351 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

Research output: Contribution to journal › Journal article › Research › peer-review

Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

Svagan, A. J., Mullertz, Anette & Löbmann, Korbinian, Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

Research output: Contribution to journal › Journal article › Research › peer-review

Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs

Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a μDissolution-Permeation model with in situ drug concentration monitoring

Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dissolution Model Development: Formulation Effects and Filter Complications

Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Survival of Lactobacillus acidophilus NCFM^® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Polymeric microcontainers improve oral bioavailability of furosemide

Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, Korbinian, 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Rhamnogalacturonan-I based microcapsules for targeted drug release

Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

Research output: Contribution to journal › Journal article › Research › peer-review

Erratum: Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine (International Journal of Pharmaceutics (2016) 502:1-2 (151-160) DOI: 10.1016/j.ijpharm.2016.02.026 )

Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 30 Jun 2016, In: International Journal of Pharmaceutics. 507, 1-2, p. 109 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Marine lipids and the bioavailability of omega-3 fatty acids

Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

Research output: Contribution to journal › Review › Research › peer-review

Structural features of colloidal species in the human fasted upper small intestine

Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

pH-triggered drug release from biodegradable microwells for oral drug delivery

Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

Research output: Contribution to journal › Journal article › Research › peer-review

Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium

Borkar, N. N., Xia, D., Holm, R., Gan, Y., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 204-10 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

Research output: Contribution to journal › Journal article › Research › peer-review

Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239

Research output: Contribution to journal › Journal article › Research › peer-review

Refining stability and dissolution rate of amorphous drug formulations

Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro models for the prediction of in vivo performance of oral dosage forms

Kostewicz, E. S., Abrahamsson, B., Brewster, M., Brouwers, J., Butler, J., Carlert, S., Dickinson, P. A., Dressman, J., Holm, R., Klein, S., Mann, J., McAllister, M., Minekus, M., Muenster, U., Mullertz, Anette , Verwei, M., Vertzoni, M., Weitschies, W. & Augustijns, P., 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 342-66 25 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8

Research output: Contribution to journal › Journal article › Research › peer-review

Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation

Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In: Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

Research output: Contribution to journal › Journal article › Research › peer-review

Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract

Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Miniaturized approach for excipient selection during the development of oral solid dosage form

Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549

Research output: Contribution to journal › Journal article › Research › peer-review

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system

Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development and rheological profiling of biosimilar mucus

Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

Research output: Contribution to journal › Conference article › Research › peer-review

Mucosal drug delivery: barriers, in vitro models and formulation strategies

Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

Research output: Contribution to journal › Review › Research › peer-review

A new approach to dissolution testing by UV imaging and finite element simulations

Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

Research output: Contribution to journal › Journal article › Research › peer-review

Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

Research output: Contribution to journal › Journal article › Research › peer-review

Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bile salts and their importance for drug absorption

Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

Research output: Contribution to journal › Review › Research › peer-review