Anette Müllertz

Anette Müllertz

Professor

Member of:

    ORCID: 0000-0003-3020-8892

    Publication year:
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    101 - 150 out of 257Page size: 50
    1. 2017
    2. Published

      From concept to in vivo testing: Microcontainers for oral drug delivery

      Mazzoni, C., Tentor, F., Strindberg, S. A., Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In: Journal of Controlled Release. 268, p. 343-351 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    3. Published

      High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

      Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

      Research output: Contribution to journal › Journal article › peer-review

    4. Published

      Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

      Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    5. Published

      Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

      Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

      Research output: Contribution to journal › Journal article › peer-review

    6. Published

      Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

      Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    7. Published

      Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

      Svagan, A. J., Mullertz, Anette & Löbmann, K., Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    8. Published

      In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    9. Published

      Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    10. Published

      Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

      Research output: Contribution to journal › Journal article › peer-review

    11. 2016
    12. Published

      Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs

      Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    13. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journal › Journal article › peer-review

    14. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    15. Published

      Evaluating Oral Drug Delivery Systems: Digestion Models.

      Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    16. Published

      Evaluating Oral Drug Delivery Systems: Dissolution Models.

      Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    17. Published

      Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

      Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    18. Published

      In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs

      Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    19. Published

      Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

      Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, K., Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    20. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    21. Published

      Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid

      Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.

      Research output: Contribution to journal › Journal article › peer-review

    22. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knøchel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    23. Published

      Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    24. Published

      Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

      Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    25. Published

      Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

      Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    26. Published

      The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

      Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    27. Published

      Polymeric microcontainers improve oral bioavailability of furosemide

      Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    28. Published

      Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach

      Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    29. Published

      Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

      Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    30. Published

      In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

      Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    31. Published

      Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

      Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, K., 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    32. Published

      Rhamnogalacturonan-I based microcapsules for targeted drug release

      Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

      Research output: Contribution to journal › Journal article › peer-review

    33. Published

      Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

      Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    34. 2015
    35. Published

      Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

      Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    36. Published

      Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    37. Published

      Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

      Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    38. Published

      Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

      Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    39. Published

      Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

      Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    40. Published

      Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

      Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    41. Published

      Marine lipids and the bioavailability of omega-3 fatty acids

      Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.

      Research output: Contribution to journal › Review › peer-review

    42. Published

      Structural features of colloidal species in the human fasted upper small intestine

      Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    43. Published

      Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    44. Published

      pH-triggered drug release from biodegradable microwells for oral drug delivery

      Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

      Research output: Contribution to journal › Journal article › peer-review

    45. Published

      Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

      Sassene, P. J., Mosgaard, M. D., Löbmann, K., Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    46. 2014
    47. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journal › Journal article › peer-review

    48. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    49. Published

      Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium

      Borkar, N. N., Xia, D., Holm, R., Gan, Y., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 204-10 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    50. Published

      Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

      Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    51. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journal › Journal article › peer-review

    52. Published

      Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

      Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    53. Published

      Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

      Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    54. Published

      Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

      Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

      Research output: Contribution to journal › Journal article › peer-review

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    ID: 1302503