Anette Müllertz

Anette Müllertz

Professor


  1. 2012
  2. Published

    SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

    Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Spatial confinement can lead to increased stability of amorphous indomethacin

    Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

    Williams, H. D., Anby, M. U., Sassene, P., Kleberg, K., Bakala-N’Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Pouton, C. W. & Porter, C. J. H., 2012, In: Molecular Pharmaceutics. 9, 11, p. 3286-3300 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations

    Williams, H. D., Sassene, P., Kleberg, K., Bakala-N'Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: Journal of Pharmaceutical Sciences. 101, 9, p. 3360-3380

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

    Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2011
  8. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

    Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    In vitro lipolysis models as a tool for the characterization of oral lilpid and surfactant based drug delivery systems

    Larsen, A. T., Sassene, P. & Mullertz, Anette , 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 245-255

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

    Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Phase transformations of amlodipine besylate solid forms

    Koradia, V. S., Lemos, A. F. F. D., Allesø, M., Diego, H. L. D., Ringkjøbing-Elema, M., Mullertz, Anette & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7, p. 2896-2910

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2010
  14. Published

    Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

    Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  15. Published

    Insights into the ultrastructure of human intestinal fluids in the fed state by electron microscopy analysis

    Mullertz, Anette , Fatouros, D., Smith, J. R., Vertzoni, M. & Rappas, C., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

    Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Selection of a lipase for development of an in vitro gastric lipid digestion model

    Larsen, A. T., Jensen, L. G., Hansen, K. K. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  18. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An updated and simplified method for bile duct cannulation of rats

    Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

    Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

    Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit

    Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In: The AAPS Journal. 12, 3, p. 465-472

    Research output: Contribution to journalReviewResearch

  23. Published

    New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

    Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

    Sassene, P. J., Knopp, M. M., Hesselkilde, J. Z., Koradia, V. S., Larsen, A. T., Rades, T. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2009
  26. Published

    Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: Effects on physicochemical properties

    Zimmermann, A., Millqvist-Fureby, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 109-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

    Fatouros, D., Walrand, I., Bergenstahl, B. & Mullertz, Anette , 2009, In: Pharmaceutical Research. 26, 2, p. 361-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

    Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Influence of the solid form of siramesine hydrochloride on its behaviour in aqueous environments

    Zimmermann, A., Tian, F., Lopez de Diego, H., Ringkjøbing Elema, M., Rantanen, Jukka, Mullertz, Anette & Hovgaard, L., 2009, In: Pharmaceutical Research. 26, 4, p. 846-854

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302503