Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. Published

      Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method

      Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

      Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Accepted/In press

      Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus

      Klitgaard, Mette, Jacobsen, Jette, Kristensen, M. N., Berthelsen, R. & Mullertz, Anette , 2024, (Accepted/In press) In: Drug Delivery and Translational Research.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

      Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

      Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

      Kleberg, K., Jacobsen, F., Fatouros, D. G. & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 8, p. 3522-3532 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

      Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)

      Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

      Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

      Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

      Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

      Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

      Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

      Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

      Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Formulation, characterization and in-vitro evaluation of self-nanoemulsifying drug delivery system containing rhamnolipid biosurfactant

      Khan, Muhammad Ayub, Ullah, K., Rahman, N. U., Mahmood, A., Mullertz, Anette , Mannan, A., Murtaza, G. & Khan, S. A., 2022, In: Journal of Drug Delivery Science and Technology. 75, 9 p., 103673.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats

      Karpf, D. M., Holm, R., Kristensen, H. G. & Mullertz, Anette , 2004, In: Pharmaceutical Research. 21, 8, p. 1413-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

      Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

      Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

      Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

      Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Design of a self-unfolding delivery concept for oral administration of macromolecules

      Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

      Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

      Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

      Research output: Contribution to journalLetterResearchpeer-review

    27. Published

      Characterization of the hydrodynamics in a miniaturized dissolution apparatus

      Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

      Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

      Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

      Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

      Ilardia-Arana, D., Kristensen, H. G. & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 2, p. 248-55 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

      Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published
    34. Published

      Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

      Holm, R., Porter, C. J. H., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2002, In: Pharmaceutical Research. 19, 9, p. 1354-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Bile salts and their importance for drug absorption

      Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    36. Published

      Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols

      Holm, R., Porsgaard, T., Porter, H., Høy, C., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2006, In: European Journal of Lipid Science and Technology. 108, 9, p. 714-722 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides

      Holm, R., Porter, C. J. H., Edwards, G. A., Mullertz, Anette , Kristensen, H. G. & Charman, W. N., 2003, In: European Journal of Pharmaceutical Sciences. 20, 1, p. 91-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

      Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

      Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Influence of bile on the absorption of halofantrine from lipid-based formulations

      Holm, R., Tønsberg, H., Jørgensen, E. B., Abedinpour, P., Farsad, S. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 281-287

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

      Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

      Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

      Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

      Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies

      Grundy, M. M. L., Abrahamse, E., Almgren, A., Alminger, M., Andres, A., Ariëns, R. M. C., Bastiaan-Net, S., Bourlieu-Lacanal, C., Brodkorb, A., Bronze, M. R., Comi, I., Couëdelo, L., Dupont, D., Durand, A., El, S. N., Grauwet, T., Heerup, C., Heredia, A., Infantes Garcia, M. R., Jungnickel, C. & 26 others, Kłosowska-Chomiczewska, I. E., Létisse, M., Macierzanka, A., Mackie, A. R., McClements, D. J., Menard, O., Meynier, A., Michalski, M. C., Mulet-Cabero, A. I., Mullertz, Anette , Payeras Perelló, F. M., Peinado, I., Robert, M., Secouard, S., Serra, A. T., Silva, S. D., Thomassen, G., Tullberg, C., Undeland, I., Vaysse, C., Vegarud, G. E., Verkempinck, S. H. E., Viau, M., Zahir, M., Zhang, R. & Carrière, F., 2021, In: Journal of Functional Foods. 82, 104497.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats

      Grove, M., Nielsen, J. L., Pedersen, G. P. & Mullertz, Anette , 2006, In: Pharmaceutical Research. 23, 11, p. 2681-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

      Grove, M., Pedersen, G. P., Nielsen, J. L. & Mullertz, Anette , 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1830-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Bioavailability of seocalcitol III: administration of lipid-based formulations to minipigs in the fasted and fed state

      Grove, M., Mullertz, Anette , Pedersen, G. P. & Nielsen, J. L., 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 8-15

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Refining stability and dissolution rate of amorphous drug formulations

      Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

      Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 1302503