Anette Müllertz

Anette Müllertz

Professor

Member of:


    1. 2017
    2. Published

      Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

      Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)

      Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

      Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants

      Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug

      Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

      Löbmann, K., Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

      Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      From concept to in vivo testing: Microcontainers for oral drug delivery

      Mazzoni, C., Tentor, F., Strindberg, S. A., Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In: Journal of Controlled Release. 268, p. 343-351 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

      Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability

      Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

      Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

      Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

      Svagan, A. J., Mullertz, Anette & Löbmann, K., Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

      Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2018
    20. Published

      The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

      Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, K., Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

      Duraipandian, S., Knopp, M. M., Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Characterization of the hydrodynamics in a miniaturized dissolution apparatus

      Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

      Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

      Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)

      Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

      López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, Lasse, Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., Jun 2018, In: Food Hydrocolloids. 79, p. 117-126 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

      Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

      Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

      Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

      Ueda, H., Wu, W., Lobmann, K., Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Are phytosomes a superior nanodelivery system for the antioxidant rutin?

      Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. 2019
    33. Published

      Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

      Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

      Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

      Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

      Research output: Contribution to journalReviewResearchpeer-review

    36. Published

      Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

      Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    37. Published

      In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

      Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

      Research output: Contribution to journalReviewResearchpeer-review

    38. Published

      Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

      Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

      Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, A., Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W. & 2 others, Reppas, C. & Augustijns, P., Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

      Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

      Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

      Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

      Research output: Contribution to journalLetterResearchpeer-review

    43. Published

      SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

      Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Polymeric Lids for Microcontainers for Oral Protein Delivery

      Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

      Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

      Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development

      Zane, P., Gieschen, H., Kersten, E., Mathias, N., Ollier, C., Johansson, P., Van den Bergh, A., Van Hemelryck, S., Reichel, A., Rotgeri, A., Schäfer, K., Mullertz, Anette & Langguth, P., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 222-231 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. 2020
    49. Published

      Six years of progress in the oral biopharmaceutics area – A summary from the IMI OrBiTo project

      Abrahamsson, B., Mcallister, M., Augustijns, P., Zane, P., Butler, J., Holm, R., Langguth, P., Lindahl, A., Mullertz, Anette , Pepin, X., Rostami-hodjegan, A., Sjögren, E., Berntsson, M. & Lennernäs, H., 1 Jul 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 236-247 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

      Bannow, J., Yorulmaz, Y., Löbmann, K., Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Milk osteopontin retains integrin-binding activity after in vitro gastrointestinal transit

      Christensen, B., Karlsen, N. J., Jorgensen, S. D. S., Jacobsen, L. N., Ostenfeld, M. S., Petersen, S. V., Mullertz, Anette & Sorensen, E. S., Jan 2020, In: Journal of Dairy Science. 103, 1, p. 42-51

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine

      Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published
    54. Published

      Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model

      Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 1302503