Anette Müllertz
Professor
- 2014
- Published
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation
Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS
Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining stability and dissolution rate of amorphous drug formulations
Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems
Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro models for the prediction of in vivo performance of oral dosage forms
Kostewicz, E. S., Abrahamsson, B., Brewster, M., Brouwers, J., Butler, J., Carlert, S., Dickinson, P. A., Dressman, J., Holm, R., Klein, S., Mann, J., McAllister, M., Minekus, M., Muenster, U., Mullertz, Anette , Verwei, M., Vertzoni, M., Weitschies, W. & Augustijns, P., 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 342-66 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading
Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation
Marizza, P., Keller, S. S., Mullertz, Anette & Boisen, A., 10 Jan 2014, In: Journal of controlled release : official journal of the Controlled Release Society. 173, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect
Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa
Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour
Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract
Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Miniaturized approach for excipient selection during the development of oral solid dosage form
Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate
Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system
Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase
Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.
Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation
Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans
Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems
Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Marine lipids and the bioavailability of omega-3 fatty acids
Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Structural features of colloidal species in the human fasted upper small intestine
Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system
Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs
Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a μDissolution-Permeation model with in situ drug concentration monitoring
Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution Model Development: Formulation Effects and Filter Complications
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity
Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs
Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers
Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid
Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract
Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers
Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs
Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach
Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems
Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems
Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, Korbinian, 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rhamnogalacturonan-I based microcapsules for targeted drug release
Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine (International Journal of Pharmaceutics (2016) 502:1-2 (151-160) DOI: 10.1016/j.ijpharm.2016.02.026 )
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 30 Jun 2016, In: International Journal of Pharmaceutics. 507, 1-2, p. 109 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model
Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302503
Most downloads
-
516
downloads
Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
319
downloads
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
306
downloads
Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › Research › peer-review
Published