Anette Müllertz

Anette Müllertz

Professor

Member of:

    ORCID: 0000-0003-3020-8892

    Publication year:
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    51 - 100 out of 268Page size: 50
    1. 2010
    2. Published

      Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

      Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

      Research output: Contribution to conference › Poster › Research

    3. Published

      Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

      Sassene, P. J., Knopp, Matthias Manne, Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit

      Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In: The AAPS Journal. 12, 3, p. 465-472

      Research output: Contribution to journal › Review › Research

    5. Published

      An updated and simplified method for bile duct cannulation of rats

      Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2011
    7. Published

      Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

      Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

      Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Phase transformations of amlodipine besylate solid forms

      Koradia, V. S., Lemos, A. F. F. D., Allesø, M., Diego, H. L. D., Ringkjøbing-Elema, M., Mullertz, Anette & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7, p. 2896-2910

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      In vitro lipolysis models as a tool for the characterization of oral lilpid and surfactant based drug delivery systems

      Larsen, A. T., Sassene, P. & Mullertz, Anette , 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 245-255

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

      Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2012
    13. Published

      In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

      Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: International Journal of Pharmaceutics. 441, 1-2, p. 323-333

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Influence of bile on the absorption of halofantrine from lipid-based formulations

      Holm, R., Tønsberg, H., Jørgensen, E. B., Abedinpour, P., Farsad, S. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 281-287

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

      Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

      Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Oral delivery of peptides and proteins using lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , 2012, In: Expert Opinion on Drug Delivery. 9, 10, p. 1289-304 16 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

      Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In: Molecular Pharmaceutics. 9, 2, p. 237-247

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Spatial confinement can lead to increased stability of amorphous indomethacin

      Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

      Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In: International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Characterising lipid lipolysis and its implication in lipid-based formulation development

      Thomas, N., Holm, R., Rades, Thomas & Mullertz, Anette , 2012, In: The AAPS journal. 14, 4, p. 860-71 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems

      Thomas, N., Mullertz, Anette , Graf, A. & Rades, T., 2012, In: Journal of Pharmaceutical Sciences. 101, 5, p. 1721-1731

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

      Williams, H. D., Anby, M. U., Sassene, P., Kleberg, K., Bakala-N’Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Pouton, C. W. & Porter, C. J. H., 2012, In: Molecular Pharmaceutics. 9, 11, p. 3286-3300 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations

      Williams, H. D., Sassene, P., Kleberg, K., Bakala-N'Goma, J., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Carrière, F., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: Journal of Pharmaceutical Sciences. 101, 9, p. 3360-3380

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2013
    26. Published

      Development and rheological profiling of biosimilar mucus

      Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

      Research output: Contribution to journal › Conference article › Research › peer-review

    27. Published

      Mucosal drug delivery: barriers, in vitro models and formulation strategies

      Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

      Research output: Contribution to journal › Review › Research › peer-review

    28. Published

      A new approach to dissolution testing by UV imaging and finite element simulations

      Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

      Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

      Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Bile salts and their importance for drug absorption

      Holm, R., Mullertz, Anette & Mu, Huiling, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 44-55 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    32. Published

      Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

      Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation

      Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems

      Li, P., Nielsen, Hanne Mørck, Fano, M. & Mullertz, Anette , Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2689-98 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    36. Published

      Lipid-based formulations for oral administration of poorly water-soluble drugs

      Mu, Huiling, Holm, R. & Mullertz, Anette , 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 215-24 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy

      Mullertz, Anette , Fatouros, D. G., Vertzoni, M. & Reppas, C., Oct 2013, In: The Journal of pharmacy and pharmacology. 65, 10, p. 1482-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

      Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose

      Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats

      Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

      Pedersen, P. B., Vilmann, Peter, Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Pt B, p. 958-65 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Polymer selection for simulation of rheological properties of human gastric fluid

      Pedersen, P. B., Vilmann, P., Bar-Shalom, Daniel, Mullertz, Anette & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 241-247

      Research output: Contribution to journal › Conference article › Research

    43. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology

      Ren, S., Mu, Huiling, Alchaer, F., Chtatou, A. & Mullertz, Anette , May 2013, In: Drug Development and Industrial Pharmacy. 39, 5, p. 799-806 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Recent developments in oral lipid-based drug delivery

      Thomas, N., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 375-382 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug Simvastatin in dogs

      Thomas, N., Holm, R., Garmer, M., Karlsson, J. J., Mullertz, Anette & Rades, Thomas, 2013, In: A A P S Journal. 15, 1, p. 219-27 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations

      Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & LFCS Consortium, L. C., Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3059-76 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 2014
    49. Published

      Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

      Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium

      Borkar, N. N., Xia, D., Holm, R., Gan, Y., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 204-10 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

      Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

      Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    55. Published

      Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

      Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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