Andrea Heinz

Andrea Heinz

Associate Professor - Promotion Programme


  1. 2007
  2. Published

    Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy

    Heinz, Andrea, Savolainen, M., Rades, Thomas & Strachan, C. J., 2007, In: European Journal of Pharmaceutical Sciences. 32, 3, p. 182-192 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Screening for differences in the amorphous state of indomethacin using multivariate visualization

    Savolainen, M., Heinz, Andrea, Strachan, C., Gordon, K. C., Yliruusi, J., Rades, Thomas & Sandler, N., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 113-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2008
  5. Published

    Characterizing an amorphous system exhibiting trace crystallinity: A case study with saquinavir

    Heinz, Andrea, Strachan, C. J., Atassi, F., Gordon, K. C. & Rades, Thomas, Jan 2008, In: Crystal Growth & Design. 8, 1, p. 119-127

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2009
  7. Understanding the solid-state forms of fenofibrate - a spectroscopic and computational study

    Heinz, Andrea, Gordon, K. C., McGoverin, C. M., Rades, Thomas & Strachan, C. J., 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 100-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Better understanding of dissolution behaviour of amorphous drugs by in situ solid-state analysis using Raman spectroscopy

    Savolainen, M., Kogermann, K., Heinz, Andrea, Aaltonen, J., Peltonen, L., Strachan, C. & Yliruusi, J., Jan 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 71-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy

    Heinz, Andrea, Strachan, C. J., Gordon, K. C. & Rades, Thomas, Aug 2009, In: The Journal of pharmacy and pharmacology. 61, 8, p. 971-88 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2010
  11. Published

    Degradation of tropoelastin by matrix metalloproteinases--cleavage site specificities and release of matrikines

    Heinz, Andrea, Jung, M. C., Duca, L., Sippl, W., Taddese, S., Ihling, C., Rusciani, A., Jahreis, G., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2010, In: F E B S Journal. 277, 8, p. 1939-56 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin collagen type I and type III

    Taddese, S., Jung, M. C., Ihling, C., Heinz, Andrea, Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2010, In: B B A - Reviews on Cancer. 1804, 4, p. 731-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2011
  14. Published

    Insights into the degradation of human elastin by matrilysin-1

    Heinz, Andrea, Taddese, S., Sippl, W., Neubert, R. H. H. & Schmelzer, C. E. H., Feb 2011, In: Biochimie. 93, 2, p. 187-94 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structure and activity of Aspergillus nidulans copper amine oxidase

    McGrath, A. P., Mithieux, S. M., Collyer, C. A., Bakhuis, J. G., van den Berg, M., Sein, A., Heinz, Andrea, Schmelzer, C., Weiss, A. S. & Guss, J. M., 28 Jun 2011, In: Biochemistry. 50, 25, p. 5718-30 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2012
  17. Published

    The action of neutrophil serine proteases on elastin and its precursor

    Heinz, Andrea, Jung, M. C., Jahreis, G., Rusciani, A., Duca, L., Debelle, L., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Jan 2012, In: Biochimie. 94, 1, p. 192-202 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Longevity of elastin in human intervertebral disc as probed by the racemization of aspartic acid

    Sivan, S., Van El, B., Merkher, Y., Schmelzer, C. E. H., Zuurmond, A., Heinz, Andrea, Wachtel, E., Varga, P., Lazary, A., Brayda-Bruno, M. & Maroudas, A., Oct 2012, In: B B A - Reviews on Cancer. 1820, 10, p. 1671-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Does human leukocyte elastase degrade intact skin elastin?

    Schmelzer, C. E. H., Jung, M. C., Wohlrab, J., Neubert, R. H. H. & Heinz, Andrea, Nov 2012, In: F E B S Journal. 279, 22, p. 4191-200 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2013
  21. Published

    In vitro cross-linking of elastin peptides and molecular characterization of the resultant biomaterials

    Heinz, Andrea, Ruttkies, C. K. H., Jahreis, G., Schräder, C. U., Wichapong, K., Sippl, W., Keeley, F. W., Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2013, In: B B A - Reviews on Cancer. 1830, 4, p. 2994-3004 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Elastin-derived peptides are new regulators of insulin resistance development in mice

    Blaise, S., Romier, B., Kawecki, C., Ghirardi, M., Rabenoelina, F., Baud, S., Duca, L., Maurice, P., Heinz, Andrea, Schmelzer, C. E. H., Tarpin, M., Martiny, L., Garbar, C., Dauchez, M., Debelle, L. & Durlach, V., Nov 2013, In: Diabetes. 62, 11, p. 3807-16 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Investigating the role of (2S,4R)-4-hydroxyproline in elastin model peptides

    Bochicchio, B., Laurita, A., Heinz, Andrea, Schmelzer, C. E. H. & Pepe, A., 9 Dec 2013, In: Biomacromolecules. 14, 12, p. 4278-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published

    Molecular-level characterization of elastin-like constructs and human aortic elastin

    Heinz, Andrea, Schräder, C. U., Baud, S., Keeley, F. W., Mithieux, S. M., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Sep 2014, In: Matrix Biology. 38, p. 12-21 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2015
  27. Published

    Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms

    Bultmann-Mellin, I., Conradi, A., Maul, A. C., Dinger, K., Wempe, F., Wohl, A. P., Imhof, T., Wunderlich, F. T., Bunck, A. C., Nakamura, T., Koli, K., Bloch, W., Ghanem, A., Heinz, Andrea, von Melchner, H., Sengle, G. & Sterner-Kock, A., Apr 2015, In: Disease models & mechanisms. 8, 4, p. 403-15 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Fingerprinting desmosine-containing elastin peptides

    Schräder, C. U., Heinz, Andrea, Majovsky, P. & Schmelzer, C. E. H., May 2015, In: Journal of the American Society for Mass Spectrometry. 26, 5, p. 762-73 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2016
  30. Cadmium toxicity investigated at the physiological and biophysical levels under environmentally relevant conditions using the aquatic model plant Ceratophyllum demersum

    Andresen, E., Kappel, S., Stärk, H., Riegger, U., Borovec, J., Mattusch, J., Heinz, Andrea, Schmelzer, C. E. H., Matoušková, Š., Dickinson, B. & Küpper, H., Jun 2016, In: New Phytologist. 210, 4, p. 1244-58 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Elastins from patients with Williams-Beuren syndrome and healthy individuals differ on the molecular level

    Heinz, Andrea, Huertas, A. C. M., Schräder, C. U., Pankau, R., Gosch, A. & Schmelzer, C. E. H., Jul 2016, In: American Journal of Medical Genetics. Part A. 170, 7, p. 1832-42 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Molecular-level insights into aging processes of skin elastin

    Mora Huertas, A. C., Schmelzer, C. E. H., Hoehenwarter, W., Heyroth, F. & Heinz, Andrea, 30 Aug 2016, In: Biochimie. 128-129, p. 163-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Prolyl hydroxylation in elastin is not random

    Schmelzer, C. E. H., Nagel, M. B. M., Dziomba, S., Merkher, Y., Sivan, S. S. & Heinz, Andrea, Oct 2016, In: B B A - Reviews on Cancer. 1860, 10, p. 2169-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2018
  35. Published

    Degradation of tropoelastin and skin elastin by neprilysin

    Mora Huertas, A. C., Schmelzer, C. E. H., Luise, C., Sippl, W., Pietzsch, M., Hoehenwarter, W. & Heinz, Andrea, 2018, In: Biochimie. 146, p. 73-78 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Elastin is heterogeneously cross-linked

    Schräder, C. U., Heinz, Andrea, Majovsky, P., Karaman, B., Brinckmann, J., Sippl, W. & Schmelzer, C. E. H., 2018, In: The Journal of Biological Chemistry. 293, 39, p. 15107-15119

    Research output: Contribution to journalJournal articleResearchpeer-review

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