Research areas

  1. Published

    Expression and display of the Hy.2E11 T cell receptor involved in the pathogenesis of MS and generation of antibodies against the DR2bMBP85-99 complex

    Dam-Tuxen, R., 2009, Copenhagen: Museum Tusculanum. 121 p.

    Research output: Book/ReportPh.D. thesisResearch

  2. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors

    Dallanoce, C., Magrone, P., Matera, C., Frigerio, F., Grazioso, G., De Amici, M., Fucile, S., Piccari, V., Frydenvang, Karla Andrea, Pucci, L., Gotti, C., Clementi, F. & De Micheli, C., 2 May 2011, In: ChemMedChem. 6, 5, p. 889-903

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations

    Dallanoce, C., Magrone, P., Bazza, P., Grazioso, G., Rizzi, L., Riganti, L., Gotti, C., Clementi, F., Frydenvang, Karla Andrea & De Amici, M., 2009, In: Chemistry & Biodiversity. 6, 2, p. 244-259

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response

    Dalgard, O., Bjøro, K., Larsen, H. R., Bjornsson, E., Holberg-Petersen, M., Skovlund, E., Reichard, O., Myrvang, B., Sundelöf, B., Ritland, S., Hellum, K., Frydén, A., Florholmen, J. & Verbaan, H., 2008, In: Hepatology. 47, 1, p. 35-42

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    In patients with HCV genotype 2 or 3 infection and RVR 14 weeks treatment is noninferior to 24 weeks: pooled analysis of two Scandinavian trials

    Dalgard, O., Bjoro, K., Larsen, H. R. & Verbaan, H., 1 May 2010, In: European Journal of Gastroenterology and Hepatology. 22, 5, p. 552-556 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    "Et tu Brute?": Troskab, dyd og identitet hos Shakespeare

    Dahl, Christian, 2008, In: Kritik. 187, p. 82-91 10 p.

    Research output: Contribution to journalJournal articleResearch

  8. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In: Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery

    Cun, D., Foged, Camilla, Yang, Mingshi, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 70-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Polymeric nanocarriers for siRNA delivery: challenges and future prospects

    Cun, D., Jensen, L. B., Nielsen, Hanne Mørck, Moghimi, S. M. & Foged, Camilla, 2008, In: Journal of Biomedical Nanotechnology. 4, 3, p. 258-275

    Research output: Contribution to journalReviewResearch

  11. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, Camilla & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The EUFEPS workshop on institutional peer review "The ultimate tool to advance the pharmaceutical sciences?" A continuing story: A continuing story

    Crommelin, D. J. A. & Bjerrum, Ole Jannik, 2008, In: European Journal of Pharmaceutical Sciences. 35, 4, p. 361-364

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes

    Crielaard, B. J., Yousefi, A., Schillemans, J. P., Vermehren, C., Buyens, K., Braeckmans, K., Lammers, T. & Storm, G., Dec 2011, In: Journal of Controlled Release. 156, 3, p. 307-314

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Concise synthesis of new bridged-nicotine analogues

    Crestey, F., Hooyberghs, G. & Kristensen, Jesper Langgaard, 4 Feb 2012, In: Tetrahedron. 68, 5, p. 1417-1421

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

    Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Synthesis of conformationally constrained glutamic acid homologues and investigation of their pharmacological profiles

    Conti, P., Pinto, A., Tamborini, L., Grazioso, G., De Sarro, G., Bräuner, Hans, Szabo, G., Hársing, L. G. & De Micheli, C., 2007, In: ChemMedChem. 2, 11, p. 1639-1647 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

    Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, Birgitte, Madsen, Ulf, Frydenvang, Karla Andrea, Colombo, A. & De Micheli, C., 2007, In: European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

    Conti, P., De Amici, M., Roda, G., Pinto, A., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte, Bräuner, Hans & De Micheli, C., 2007, In: Tetrahedron. 63, 10, p. 2249-2256

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: Design, synthesis, and pharmacological characterization

    Conti, P., Pinto, A., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte, Bräuner, Hans, Hansen, K. B., Landucci, E., Pellegrini-Giampietro, D. E., De Sarro, G., Donato Di Paola, E. & De Micheli, C., 2010, In: ChemMedChem. 5, 9, p. 1465-1475

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of active metabolites in the use of opioids

    Coller, J. K., Christrup, Lona Louring & Somogyi, A. A., 2009, In: European Journal of Clinical Pharmacology. 65, 2, p. 121-139

    Research output: Contribution to journalReviewResearch

  21. Published

    Lack of influence of CYP2D6 genotype on the clearance of (R)-, (S)- and racemic-methadone.

    Coller, J. K., Jørgensen, Carsten, Foster, D. J. R., James, H., Gillis, D., Christrup, Lona Louring & Somogyi, A. A., 2007, In: International Journal of Clinical Pharmacology and Therapeutics. 45, 7, p. 410-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Oral bioavailability and bone-sparing effects of estetrol in an osteoporosis model

    Coelingh Bennink, H. J. T., Heegaard, Anne-Marie, Visser, M., Holinka, C. F. & Christiansen, C., 2008, In: Climacteric. 11, 1, p. 2-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Opioid and cannabinoid receptors

    Clausen, Rasmus Prætorius & Hansen, Harald S., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 313-328

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  24. Published

    Ind i hjernen med nye stoffer

    Clausen, Rasmus Prætorius, Nielsen, S. D., Kristensen, Jesper Langgaard & Hansen, K. B., 2009, In: Lægemiddelforskning. p. 34-36

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

    Clausen, Rasmus Prætorius, Naur, P., Kristensen, Anders Skov, Greenwood, J. R., Strange, M., Bräuner, Hans, Jensen, Anders A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, Birgitte, Pickering, Darryl S, Brehm, L., Gajhede, Michael, Krogsgaard-Larsen, Povl & Kastrup, Jette Sandholm Jensen, 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4911-4922

    Research output: Contribution to journalJournal articleResearchpeer-review