Protein Analyse

  1. 2024
  2. Published

    Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

    Grauslund, L. R., Ständer, S., Veggi, D., Andreano, E., Rand, Kasper Dyrberg & Norais, N., 2024, In: Molecular & cellular proteomics : MCP. 23, 3, 100734.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties

    Code, C., Qiu, D., Solov'yov, I. A., Lee, J., Shin, H., Roland, C., Sagui, C., Houde, D., Rand, Kasper Dyrberg & Jørgensen, T. J. D., 2023, In: Journal of the American Chemical Society. 145, 44, p. 23925-23938

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS

    Lambert, Thomas Ole Tandrup, Gramlich, M., Stutzke, L., Smith, L., Deng, D., Kaiser, P. D., Rothbauer, U., Benesch, J. L. P., Wagner, C., Koenig, M., Pompach, P., Novak, P., Zeck, A. & Rand, Kasper Dyrberg, 2023, In: Journal of the American Society for Mass Spectrometry. 34, 11, p. 2556–2566

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction

    Sheff, J., Kelly, J., Foss, M., Brunette, E., Kemmerich, K., van Faassen, H., Raphael, S., Hussack, G., Comamala, G., Rand, Kasper Dyrberg & Stanimirovic, D. B., 2023, In: Journal of Biochemistry. 173, 2, p. 95-105

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.

    Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT

    Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Serrulatane diterpenoids with unusual side chain modifications from root bark of Eremophila longifolia

    Rasmussen, L. F., Anton, Jennifer, Kjaerulff, Louise, Zhao, Yong, Semple, S. J., Ndi, C., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 203, 14 p., 113408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The dopamine transporter antiports potassium to increase the uptake of dopamine

    Schmidt, S. G., Malle, M. G., Nielsen, A. K., Bohr, S. S., Pugh, Ciara Frances, Nielsen, Jeppe Cederholm, Poulsen, I. H., Rand, Kasper Dyrberg, Hatzakis, Nikos & Loland, Claus Juul, 2022, In: Nature Communications. 13, 1, 12 p., 2446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Translation of a practical laboratory exercise into a theoretical laboratory exercise

    Trabjerg, Esben, 2022, In: Improving University Science Teaching and Learning - Pedagogical Projects. 17, p. 119-130

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2021
  14. Published

    Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments

    Calvaresi, V., Truelsen, L. T., Larsen, S. B., Petersen, N. H. T., Kirkegaard, T. & Rand, Kasper Dyrberg, 2021, In: Communications Biology . 4, 1369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Epitope Mapping of Polyclonal Antibodies by Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)

    Ständer, S., Grauslund, L. R., Scarselli, M., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 34, p. 11669–11678

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies

    Grauslund, L. R., Calvaresi, V., Pansegrau, W., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Journal of the American Society for Mass Spectrometry. 32, 7, p. 1575–1582

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples

    Calvaresi, V., Redsted, A., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 33, p. 11406–11414

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins

    Comamala, G., Krogh, C. C., Nielsen, V. S., Kutter, Jörg P., Voglmeir, J. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 49, p. 16330–16340

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry

    Merkle, P. S., Trabjerg, Esben, Hongjian, S., Ferber, M., Cuendet, M. A., Jorgensen, T. J. D., Luescher, I., Irving, M., Zoete, V., Michielin, O. & Rand, Kasper Dyrberg, 2021, In: Biochemistry. 60, 11, p. 859-872

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Revealing the dynamic allosteric changes required for formation of the cysteine synthase complex by hydrogen-deuterium exchange mass spectrometry

    Rosa, B., Dickinson, E. R., Marchetti, M., Campanini, B., Pioselli, B., Bettati, S. & Rand, Kasper Dyrberg, 2021, In: Molecular and Cellular Proteomics. 20, 12 p., 100098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2020
  22. Published

    Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor

    Comamala, G., Wagner, C., de la Torre, P. S., Jakobsen, R. U., Hilger, M., Brouwer, H. & Rand, Kasper Dyrberg, 8 Jun 2020, In: Analytica Chimica Acta. 1115, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    An intact C-terminal end of albumin is required for its long half-life in humans

    Nilsen, J., Trabjerg, Esben, Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., 20 Apr 2020, In: Communications Biology. 3, 1, 11 p., 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines

    Castelli, R., Scalvini, L., Vacondio, F., Lodola, A., Anselmi, M., Vezzosi, S., Carmi, C., Bassi, M., Ferlenghi, F., Rivara, S., Möller, I. R., Rand, K. D., Daglian, J., Wei, D., Dotsey, E. Y., Ahmed, F., Jung, K-M., Stella, N., Singh, S., Mor, M. & 1 others, Piomelli, D., 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1261-1280

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis

    Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, Kasper Dyrberg & Teilum, Kaare, 2020, In: PeerJ. 8, 17 p., e9408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Deglycosylation by the Acidic Glycosidase PNGase H+ Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry

    Comamala, G., Madsen, J. B., Voglmeir, J., Du, Y., Jensen, P. F., Østerlund, E. C., Trelle, M. B. & Rand, Kasper Dyrberg, 2020, In: Journal of the American Society for Mass Spectrometry. 31, 11, p. 2305-2312

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes

    Guo, R., Comamala, G., Yang, H., Gramlich, M., Du, Y., Wang, T., Zeck, A., Rand, Kasper Dyrberg, Liu, L. & Voglmeir, J., 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 7 p., 741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

    Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Molecular Basis of the Mechanisms Controlling MASTL

    Hermida, D., Mortuza, G. B., Pedersen, Anna-Kathrine, Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS

    Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Thiol-ene microfluidic chip for fast on-chip sample clean-up, separation and ESI mass spectrometry of peptides and proteins

    Svejdal, R. R., Sticker, Drago, Sønderby, C., Kutter, Jörg P. & Rand, Kasper Dyrberg, 2020, In: Analytica Chimica Acta. 1140, p. 168-177 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2019
  33. Published

    An intact C-terminal end of albumin is required for long serum half-life

    Nilsen, J., Trabjerg, E., Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., Dec 2019, p. 19. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  34. Published

    Investigating the Conformational Response of the Sortilin Receptor upon Binding Endogenous Peptide- and Protein Ligands by HDX-MS

    Trabjerg, Esben, Abu-Asad, N., Wan, Z., Kartberg, F., Christensen, S. & Rand, Kasper Dyrberg, 2 Jul 2019, In: Structure. 27, 7, p. 1103-1113.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

    Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., Gross, M. L., Guttman, M., Hamuro, Y., Heck, A. J. R., Houde, D., Iacob, R. E., Jorgensen, T. J. D., Kaltashov, I. A. & 20 others, Klinman, J. P., Konermann, L., Man, P., Mayne, L., Pascal, B. D., Reichmann, D., Skehel, M., Snijder, J., Strutzenberg, T. S., Underbakke, E. S., Wagner, C., Wales, T. E., Walters, B. T., Weis, D. D., Wilson, D. J., Wintrode, P. L., Zhang, Z., Zheng, J., Schriemer, D. C. & Rand, Kasper Dyrberg, Jul 2019, In: Nature Methods. 16, 7, p. 595-602

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A. & 16 others, Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 May 2019, In: Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study

    Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P. C., Bernfur, K., Borchers, C. H., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T. N., Degliesposti, G., Dong, M-Q., Edinger, N., Emanuelsson, C., Gay, M. & 53 others, Gomes-Neto, F., Gozzo, F. C., Gutierrez, C. B., Haupt, C., Heck, A. J. R., Herzog, F., Huang, L., Hoopmann, M. R., Kalisman, N., Klykov, O., Kukačka, Z., Liu, F., MacCoss, M. J., Mechtler, K., Mesika, R., Moritz, R. L., Nagaraj, N., Nesati, V., Neves-Fereira, A. G. C., Ninnis, R., Novák, P., O'Reilly, F. J., Pelzing, M., Petrotchenko, E. V., Piersimoni, L., Plasencia, M., Pukala, T. L., Rand, Kasper Dyrberg, Rappsilber, J., Reichman, D., Sailer, C., Sarnowski, C. P., Scheltema, R. A., Schmidt, C., Schriemer, D. C., Shi, Y., Skehel, J. M., Slavin, M., Sobott, F., Solis-Mezarino, V., Stephanowitz, H., Stengel, F., Stieger, C. E., Trabjerg, Esben, Trnka, M. J., Vilaseca, M., Viner, R., Xiang, Y., Yılmaz, Ş., Zelter, A., Ziemianowicz, D. S., Leitner, A. & Sinz, A., 2 May 2019, In: Analytical Chemistry. 91, 11, p. 6953-6961

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A post-translational modification of human Norovirus capsid protein attenuates glycan binding

    Mallagaray, A., Creutznacher, R., Dülfer, J., Mayer, P. H. O., Grimm, L. L., Orduña, J. M., Trabjerg, Esben, Stehle, T., Rand, Kasper Dyrberg, Blaum, B. S., Uetrecht, C. & Peters, T., 21 Mar 2019, In: Nature Communications. 10, 1, 14 p., 1320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Probing the Dissociation of Protein Complexes by Means of Gas-Phase H/D Exchange Mass Spectrometry

    Mistarz, U. H., Chandler, S. A., Brown, J. M., Benesch, J. L. P. & Rand, Kasper Dyrberg, 15 Jan 2019, In: Journal of the American Society for Mass Spectrometry. 30, 1, p. 45-57 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Thiol-ene microfluidic chip for performing hydrogen/deuterium exchange of proteins at sub-second timescales

    Svejdal, R. R., Dickinson, E. R., Sticker, Drago, Kutter, Jörg P. & Rand, Kasper Dyrberg, 15 Jan 2019, In: Analytical Chemistry. 91, 2, p. 1309-1317

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

    Möller, I. R., Slivacka, M., Hausner, J., Nielsen, A. K., Pospisilova, E., Rand, Kasper Dyrberg, Liskova, R., Polak, M., Loland, Claus Juul, Kadek, A., Man, P. & Rand, Kasper Dyrberg, 2019, In: Analytical Chemistry. 91, 17, p. 10970-10978 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

    Jensen, P. F., Kadziola, Anders, Comamala, G., Segura, D. R., Anderson, L., Poulsen, Jens-Christian Navarro, Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, Leila & Rand, Kasper Dyrberg, 2019, In: Cell Chemical Biology. 26, 2, p. 191-202.e1-e6 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Substrate-Induced Conformational Dynamics of the Dopamine Transporter

    Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Substrate-induced conformational dynamics of the dopamine transporter

    Nielsen, A. K., Möller, I. R., Wang, Yong, Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2018
  50. Published

    Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs

    Nguyen, T. T. T. N., Mistarz, U. H., Costa, N., Herbet, A., Boquet, D., Becher, F. & Rand, Kasper Dyrberg, 10 Sep 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 159, p. 384-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

    Trabjerg, Esben, Nazari, Z. E. & Rand, Kasper Dyrberg, Sep 2018, In: Trends in Analytical Chemistry. 106, p. 125-138

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Nanoliter-Scale Electromembrane Extraction and Enrichment in a Microfluidic Chip

    Hansen, F. A., Sticker, Drago, Kutter, Jörg P., Petersen, Nickolaj J. & Pedersen-Bjergaard, Stig, 7 Aug 2018, In: Analytical Chemistry. 90, 15, p. 9322-9329

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions

    Przygońska, K., Poznański, J., Mistarz, U. H., Rand, Kasper Dyrberg & Dadlez, M., 6 Aug 2018, In: PLoS One. 13, 8, p. 1-25 25 p., e0201761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Installation, validation, and application examples of two instrumental setups for gas-phase HDX-MS analysis of peptides and proteins

    Mistarz, U. H. & Rand, Kasper Dyrberg, 15 Jul 2018, In: Methods. 144, p. 113-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase

    Moroz, O. V., Jensen, P. F., Mcdonald, S. P., Mcgregor, N., Blagova, E., Comamala, G., Segura, D. R., Anderson, L., Vasu, S. M., Rao, V. P., Giger, L., Sørensen, T. H., Monrad, R. N., Svendsen, A., Nielsen, J. E., Henrissat, B., Davies, G. J., Brumer, H., Rand, Kasper Dyrberg & Wilson, K. S., 6 Jul 2018, In: ACS Catalysis. 8, 7, p. 6021-6034

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    An all thiol-ene microchip for solid phase extraction featuring an in situ polymerized monolith and integrated 3D replica-molded emitter for direct electrospray mass spectrometry

    Jonsson, A., Lafleur, J. P., Sticker, Drago & Kutter, Jörg P., 28 Jun 2018, In: Analytical Methods. 10, 24, p. 2854-2862

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles

    Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, Kasper Dyrberg, Godiksen, H., Andersen, P., Follmann, F. & Foged, Camilla, Jun 2018, In: Journal of Pharmaceutical Sciences. 107, 6, p. 1690-1700 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix

    Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, Kasper Dyrberg, Scharnagl, C. & Langosch, D., 27 Feb 2018, In: Biochemistry. 57, 8, p. 1326-1337 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT: Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Robert Vandenberg

    Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 2018, In: Science Advances. 4, 5, 12 p., eaar6179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    UV Photodissociation Mass Spectrometry Accurately Localize Sites of Backbone Deuteration in Peptides

    Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, Kasper Dyrberg, 2018, In: Analytical Chemistry. 90, 2, p. 1077-1080 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2017
  62. Published

    Photodissociation Mass Spectrometry Accurately Localizes Sites of Backbone Deuteration in Peptides

    Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, Kasper Dyrberg, 14 Nov 2017

    Research output: Other contributionResearch

  63. Published

    Conformational characterization of nerve growth factor-β reveals that its regulatory pro-part domain stabilizes three loop regions in its mature part

    Trabjerg, Esben, Kartberg, F., Christensen, S. & Rand, Kasper Dyrberg, 6 Oct 2017, In: Journal of Biological Chemistry. 292, 40, p. 16665-16676 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

    Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, Ikhlaq Hussain, Sauerwein, R. W., Theisen, Michael & Rand, Kasper Dyrberg, 1 Sep 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Partial Unwinding of Transmembrane Helices Facilitates Alternating Access in the Neurotransmitter: Sodium Symporter LeuT

    Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 28 Jun 2017

    Research output: Other contributionResearch

  66. Published

    Back Cover: Mapping the Interactions of Selective Biochemical Probes of Antibody Conformation by Hydrogen-Deuterium Exchange Mass Spectrometry (ChemBioChem 11/2017)

    Leurs, U., Beck, H., Bonnington, L., Lindner, I., Pol, E. & Rand, Kasper Dyrberg, 1 Jun 2017, In: ChemBioChem.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

    Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, Kasper Dyrberg, Sauerwein, R. W. & Theisen, Michael, 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. 2016
  69. Published

    Probing the Binding Interfaces of Protein Complexes Using Gas-Phase H/D Exchange Mass Spectrometry

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Feb 2016, In: Structure. 24, 2, p. 310-318 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Analytical Techniques in the Pharmaceutical Sciences

    Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer Publishing Company, p. 253-289 36 p. (Advances in Delivery Science and Technology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  71. 2015
  72. Published

    Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry

    Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  73. 2014
  74. Published

    Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Dec 2014, In: Analytical Chemistry. 86, 23, p. 11868-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. 2011
  77. Published

    Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry

    Rand, Kasper Dyrberg, Lund, F. W., Amon, S. & Jørgensen, Thomas, Apr 2011, In: International Journal of Mass Spectrometry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. 2004
  79. Published

    Die klinische wirksamkeit der sublingualen und subkutanen birkenpollenallergenspezifischen immuntherapie: Eine randomisierte, plazebokontrollierte, doppelblinde double-dummy-studie

    Khinchi, M. S., Poulsen, Lars K., Carat, F., André, C., Hansen, Anton Berg & Malling, H. J., Sep 2004, In: Allergologie. 27, 9, p. 355-366 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review