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Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT
Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.Research output: Contribution to journal › Journal article › Research › peer-review
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Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples
Calvaresi, V., Redsted, A., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 33, p. 11406–11414Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments
Calvaresi, V., Truelsen, L. T., Larsen, S. B., Petersen, N. H. T., Kirkegaard, T. & Rand, Kasper Dyrberg, 2021, In: Communications Biology . 4, 1369.Research output: Contribution to journal › Journal article › Research › peer-review
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Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines
Castelli, R., Scalvini, L., Vacondio, F., Lodola, A., Anselmi, M., Vezzosi, S., Carmi, C., Bassi, M., Ferlenghi, F., Rivara, S., Möller, I. R., Rand, K. D., Daglian, J., Wei, D., Dotsey, E. Y., Ahmed, F., Jung, K-M., Stella, N., Singh, S., Mor, M. & 1 others, , 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1261-1280Research output: Contribution to journal › Journal article › Research › peer-review
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Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties
Code, C., Qiu, D., Solov'yov, I. A., Lee, J., Shin, H., Roland, C., Sagui, C., Houde, D., Rand, Kasper Dyrberg & Jørgensen, T. J. D., 2023, In: Journal of the American Chemical Society. 145, 44, p. 23925-23938Research output: Contribution to journal › Journal article › Research › peer-review
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Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins
Comamala, G., Krogh, C. C., Nielsen, V. S., Kutter, Jörg P., Voglmeir, J. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 49, p. 16330–16340Research output: Contribution to journal › Journal article › Research › peer-review
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Deglycosylation by the Acidic Glycosidase PNGase H+ Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry
Comamala, G., Madsen, J. B., Voglmeir, J., Du, Y., Jensen, P. F., Østerlund, E. C., Trelle, M. B. & Rand, Kasper Dyrberg, 2020, In: Journal of the American Society for Mass Spectrometry. 31, 11, p. 2305-2312Research output: Contribution to journal › Journal article › Research › peer-review
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Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor
Comamala, G., Wagner, C., de la Torre, P. S., Jakobsen, R. U., Hilger, M., Brouwer, H. & Rand, Kasper Dyrberg, 8 Jun 2020, In: Analytica Chimica Acta. 1115, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular architecture of the Jumonji C family histone demethylase KDM5B
Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid
Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661Research output: Contribution to journal › Journal article › Research › peer-review
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Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)
Grauslund, L. R., Ständer, S., Veggi, D., Andreano, E., Rand, Kasper Dyrberg & Norais, N., 2024, In: Molecular & cellular proteomics : MCP. 23, 3, 100734.Research output: Contribution to journal › Journal article › Research › peer-review
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Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies
Grauslund, L. R., Calvaresi, V., Pansegrau, W., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Journal of the American Society for Mass Spectrometry. 32, 7, p. 1575–1582Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes
Guo, R., Comamala, G., Yang, H., Gramlich, M., Du, Y., Wang, T., Zeck, A., Rand, Kasper Dyrberg, Liu, L. & Voglmeir, J., 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 7 p., 741.Research output: Contribution to journal › Journal article › Research › peer-review
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PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.
Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanoliter-Scale Electromembrane Extraction and Enrichment in a Microfluidic Chip
Hansen, F. A., Sticker, Drago, Kutter, Jörg P., Petersen, Nickolaj J. & Pedersen-Bjergaard, Stig, 7 Aug 2018, In: Analytical Chemistry. 90, 15, p. 9322-9329Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Basis of the Mechanisms Controlling MASTL
Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343Research output: Contribution to journal › Journal article › Research › peer-review
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Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb
Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, , 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345Research output: Contribution to journal › Journal article › Research › peer-review
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Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb
Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A. & 16 others, , 2 May 2019, In: Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix
Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, Kasper Dyrberg, Scharnagl, C. & Langosch, D., 27 Feb 2018, In: Biochemistry. 57, 8, p. 1326-1337 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study
Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P. C., Bernfur, K., Borchers, C. H., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T. N., Degliesposti, G., Dong, M-Q., Edinger, N., Emanuelsson, C., Gay, M. & 53 others, , 2 May 2019, In: Analytical Chemistry. 91, 11, p. 6953-6961Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity
Jensen, P. F., Kadziola, Anders, Comamala, G., Segura, D. R., Anderson, L., Poulsen, Jens-Christian Navarro, Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, Leila & Rand, Kasper Dyrberg, 2019, In: Cell Chemical Biology. 26, 2, p. 191-202.e1-e6 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circularized and solubility-enhanced MSPs facilitate simple and high-yield production of stable nanodiscs for studies of membrane proteins in solution
Johansen, Nicolai Tidemand, Tidemand, Frederik Grønbæk, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Pedersen, Martin Cramer & Arleth, Lise, May 2019, In: F E B S Journal. 286, 9, p. 1734-1751Research output: Contribution to journal › Journal article › Research › peer-review
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An all thiol-ene microchip for solid phase extraction featuring an in situ polymerized monolith and integrated 3D replica-molded emitter for direct electrospray mass spectrometry
Jonsson, A., Lafleur, J. P., Sticker, Drago & Kutter, Jörg P., 28 Jun 2018, In: Analytical Methods. 10, 24, p. 2854-2862Research output: Contribution to journal › Journal article › Research › peer-review
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Die klinische wirksamkeit der sublingualen und subkutanen birkenpollenallergenspezifischen immuntherapie: Eine randomisierte, plazebokontrollierte, doppelblinde double-dummy-studie
Khinchi, M. S., Poulsen, Lars K., Carat, F., André, C., Hansen, Anton Berg & Malling, H. J., Sep 2004, In: Allergologie. 27, 9, p. 355-366 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS
Lambert, Thomas Ole Tandrup, Gramlich, M., Stutzke, L., Smith, L., Deng, D., Kaiser, P. D., Rothbauer, U., Benesch, J. L. P., Wagner, C., Koenig, M., Pompach, P., Novak, P., Zeck, A. & Rand, Kasper Dyrberg, 2023, In: Journal of the American Society for Mass Spectrometry. 34, 11, p. 2556–2566Research output: Contribution to journal › Journal article › Research › peer-review
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
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The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study
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227
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
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Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)
Research output: Contribution to journal › Journal article › Research › peer-review
Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction
Research output: Contribution to journal › Journal article › Research › peer-review
Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS
Research output: Contribution to journal › Journal article › Research › peer-review