- Published
Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry
Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Back Cover: Mapping the Interactions of Selective Biochemical Probes of Antibody Conformation by Hydrogen-Deuterium Exchange Mass Spectrometry (ChemBioChem 11/2017)
Leurs, U., Beck, H., Bonnington, L., Lindner, I., Pol, E. & Rand, Kasper Dyrberg, 1 Jun 2017, In: ChemBioChem.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical Techniques in the Pharmaceutical Sciences
Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer Publishing Company, p. 253-289 36 p. (Advances in Delivery Science and Technology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry
Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A post-translational modification of human Norovirus capsid protein attenuates glycan binding
Mallagaray, A., Creutznacher, R., Dülfer, J., Mayer, P. H. O., Grimm, L. L., Orduña, J. M., Trabjerg, Esben, Stehle, T., Rand, Kasper Dyrberg, Blaum, B. S., Uetrecht, C. & Peters, T., 21 Mar 2019, In: Nature Communications. 10, 1, 14 p., 1320.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., Gross, M. L., Guttman, M., Hamuro, Y., Heck, A. J. R., Houde, D., Iacob, R. E., Jorgensen, T. J. D., Kaltashov, I. A. & 20 others, , Jul 2019, In: Nature Methods. 16, 7, p. 595-602Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Partial Unwinding of Transmembrane Helices Facilitates Alternating Access in the Neurotransmitter: Sodium Symporter LeuT
Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 28 Jun 2017Research output: Other contribution › Research
- Published
Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry
Merkle, P. S., Trabjerg, Esben, Hongjian, S., Ferber, M., Cuendet, M. A., Jorgensen, T. J. D., Luescher, I., Irving, M., Zoete, V., Michielin, O. & Rand, Kasper Dyrberg, 2021, In: Biochemistry. 60, 11, p. 859-872Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT: Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Robert Vandenberg
Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 2018, In: Science Advances. 4, 5, 12 p., eaar6179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the Dissociation of Protein Complexes by Means of Gas-Phase H/D Exchange Mass Spectrometry
Mistarz, U. H., Chandler, S. A., Brown, J. M., Benesch, J. L. P. & Rand, Kasper Dyrberg, 15 Jan 2019, In: Journal of the American Society for Mass Spectrometry. 30, 1, p. 45-57 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the Binding Interfaces of Protein Complexes Using Gas-Phase H/D Exchange Mass Spectrometry
Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Feb 2016, In: Structure. 24, 2, p. 310-318 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite
Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, Ikhlaq Hussain, Sauerwein, R. W., Theisen, Michael & Rand, Kasper Dyrberg, 1 Sep 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Installation, validation, and application examples of two instrumental setups for gas-phase HDX-MS analysis of peptides and proteins
Mistarz, U. H. & Rand, Kasper Dyrberg, 15 Jul 2018, In: Methods. 144, p. 113-124Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale
Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Dec 2014, In: Analytical Chemistry. 86, 23, p. 11868-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV Photodissociation Mass Spectrometry Accurately Localize Sites of Backbone Deuteration in Peptides
Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, Kasper Dyrberg, 2018, In: Analytical Chemistry. 90, 2, p. 1077-1080 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photodissociation Mass Spectrometry Accurately Localizes Sites of Backbone Deuteration in Peptides
Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, Kasper Dyrberg, 14 Nov 2017Research output: Other contribution › Research
- Published
Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase
Moroz, O. V., Jensen, P. F., Mcdonald, S. P., Mcgregor, N., Blagova, E., Comamala, G., Segura, D. R., Anderson, L., Vasu, S. M., Rao, V. P., Giger, L., Sørensen, T. H., Monrad, R. N., Svendsen, A., Nielsen, J. E., Henrissat, B., Davies, G. J., Brumer, H., Rand, Kasper Dyrberg & Wilson, K. S., 6 Jul 2018, In: ACS Catalysis. 8, 7, p. 6021-6034Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational dynamics of the human serotonin transporter during substrate and drug binding
Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS
Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments
Möller, I. R., Slivacka, M., Hausner, J., Nielsen, A. K., Pospisilova, E., Rand, Kasper Dyrberg, Liskova, R., Polak, M., Loland, Claus Juul, Kadek, A., Man, P. & Rand, Kasper Dyrberg, 2019, In: Analytical Chemistry. 91, 17, p. 10970-10978 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs
Nguyen, T. T. T. N., Mistarz, U. H., Costa, N., Herbet, A., Boquet, D., Becher, F. & Rand, Kasper Dyrberg, 10 Sep 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 159, p. 384-392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate-Induced Conformational Dynamics of the Dopamine Transporter
Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Substrate-induced conformational dynamics of the dopamine transporter
Nielsen, A. K., Möller, I. R., Wang, Y., Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An intact C-terminal end of albumin is required for long serum half-life
Nilsen, J., Trabjerg, E., Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., Dec 2019, p. 19. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
An intact C-terminal end of albumin is required for its long half-life in humans
Nilsen, J., Trabjerg, Esben, Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., 20 Apr 2020, In: Communications Biology. 3, 1, 11 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
337
downloads
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
237
downloads
The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
228
downloads
Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)
Research output: Contribution to journal › Journal article › Research › peer-review
Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction
Research output: Contribution to journal › Journal article › Research › peer-review
Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS
Research output: Contribution to journal › Journal article › Research › peer-review