Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine. / Kongshaug, K. E.; Pedersen-Bjergaard, S.; Rasmussen, K. E.; Krogh, M.

In: Chromatographia, Vol. 50, No. 3-4, 01.09.1999, p. 247-252.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kongshaug, KE, Pedersen-Bjergaard, S, Rasmussen, KE & Krogh, M 1999, 'Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine', Chromatographia, vol. 50, no. 3-4, pp. 247-252. https://doi.org/10.1007/BF02490660

APA

Kongshaug, K. E., Pedersen-Bjergaard, S., Rasmussen, K. E., & Krogh, M. (1999). Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine. Chromatographia, 50(3-4), 247-252. https://doi.org/10.1007/BF02490660

Vancouver

Kongshaug KE, Pedersen-Bjergaard S, Rasmussen KE, Krogh M. Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine. Chromatographia. 1999 Sep 1;50(3-4):247-252. https://doi.org/10.1007/BF02490660

Author

Kongshaug, K. E. ; Pedersen-Bjergaard, S. ; Rasmussen, K. E. ; Krogh, M. / Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine. In: Chromatographia. 1999 ; Vol. 50, No. 3-4. pp. 247-252.

Bibtex

@article{43edd0e639384723a4218945e9deee9d,
title = "Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine",
abstract = "Impurity profiling of ecstacy and amphetamine seizures was accomplished by solid-phase microextraction (SPME) combined with capillary gas chromatography (GC). Samples were dissolved in 0.1 M aqueous acetate buffer (pH 5.0) as the only manual operation and subsequently subjected to SPME-GC. Ecstacy tablets were analyzed by head-space SPME to avoid contamination of SPME fibers with insoluble tablet components, while illicit amphetamine powders were exposed to immersed SPME. A SPME fiber of polydimethylsiloxane- divinylbenzene was found to provide excellent extraction of both polar and non-polar impurities. For both illicit ecstacy and amphetamine, complex impurity profiles were obtained by SPME providing a high information content. For ecstacy, profiles (relative peak areas) were repeatable within 2.2 to 12.6% RSD (n = 6), while similar data on amphetamine varied between 2.0 and 10.9 % RSD (n = 6). No carry-over was observed although each fiber was used for 50 to 100 extractions.",
keywords = "Amphetamine, Capillary gas chromatography, Ecstacy, Solid-phase microextraction",
author = "Kongshaug, {K. E.} and S. Pedersen-Bjergaard and Rasmussen, {K. E.} and M. Krogh",
year = "1999",
month = sep,
day = "1",
doi = "10.1007/BF02490660",
language = "English",
volume = "50",
pages = "247--252",
journal = "Chromatographia",
issn = "0009-5893",
publisher = "Springer",
number = "3-4",

}

RIS

TY - JOUR

T1 - Solid-phase microextraction/capillary gas chromatography for the profiling of confiscated ecstacy and amphetamine

AU - Kongshaug, K. E.

AU - Pedersen-Bjergaard, S.

AU - Rasmussen, K. E.

AU - Krogh, M.

PY - 1999/9/1

Y1 - 1999/9/1

N2 - Impurity profiling of ecstacy and amphetamine seizures was accomplished by solid-phase microextraction (SPME) combined with capillary gas chromatography (GC). Samples were dissolved in 0.1 M aqueous acetate buffer (pH 5.0) as the only manual operation and subsequently subjected to SPME-GC. Ecstacy tablets were analyzed by head-space SPME to avoid contamination of SPME fibers with insoluble tablet components, while illicit amphetamine powders were exposed to immersed SPME. A SPME fiber of polydimethylsiloxane- divinylbenzene was found to provide excellent extraction of both polar and non-polar impurities. For both illicit ecstacy and amphetamine, complex impurity profiles were obtained by SPME providing a high information content. For ecstacy, profiles (relative peak areas) were repeatable within 2.2 to 12.6% RSD (n = 6), while similar data on amphetamine varied between 2.0 and 10.9 % RSD (n = 6). No carry-over was observed although each fiber was used for 50 to 100 extractions.

AB - Impurity profiling of ecstacy and amphetamine seizures was accomplished by solid-phase microextraction (SPME) combined with capillary gas chromatography (GC). Samples were dissolved in 0.1 M aqueous acetate buffer (pH 5.0) as the only manual operation and subsequently subjected to SPME-GC. Ecstacy tablets were analyzed by head-space SPME to avoid contamination of SPME fibers with insoluble tablet components, while illicit amphetamine powders were exposed to immersed SPME. A SPME fiber of polydimethylsiloxane- divinylbenzene was found to provide excellent extraction of both polar and non-polar impurities. For both illicit ecstacy and amphetamine, complex impurity profiles were obtained by SPME providing a high information content. For ecstacy, profiles (relative peak areas) were repeatable within 2.2 to 12.6% RSD (n = 6), while similar data on amphetamine varied between 2.0 and 10.9 % RSD (n = 6). No carry-over was observed although each fiber was used for 50 to 100 extractions.

KW - Amphetamine

KW - Capillary gas chromatography

KW - Ecstacy

KW - Solid-phase microextraction

UR - http://www.scopus.com/inward/record.url?scp=0032792567&partnerID=8YFLogxK

U2 - 10.1007/BF02490660

DO - 10.1007/BF02490660

M3 - Journal article

AN - SCOPUS:0032792567

VL - 50

SP - 247

EP - 252

JO - Chromatographia

JF - Chromatographia

SN - 0009-5893

IS - 3-4

ER -

ID: 231654479