Drug Delivery and Biophysics of Biopharmaceuticals

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  1. 2015
  2. Published

    Penetratin-mediated transepithelial insulin pemeation: Importance of complexation?

    Kristensen, Mie, Foderà, Vito & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  3. Published

    Preferential interactions and the effect of protein PEGylation

    Holm, L. S., Thulstrup, Peter Waaben, Kasimova, M. R. & van de Weert, Marco, 2015, In: PLOS ONE. 10, 7, 18 p., e0133584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers

    Kristensen, Mie & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  5. Published

    Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro

    Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2014
  7. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

    Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Epithelial permeation and absorption mechanisms of biopharmaceuticals

    Nielsen, Hanne Mørck, 1 Oct 2014, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies. Springer US, Vol. 9781461495246. p. 99-122 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  9. Published

    Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures

    Foderà, Vito, Vetri, V., Wind, T. S., Noppe, W., Cornett, Claus, Donald, A. M., Morozova-Roche, L. A. & Vestergaard, Bente, 18 Sep 2014, In: Journal of Physical Chemistry Letters. 5, 18, p. 3254-3258 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

    Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    One-Step Production of Protein-Loaded PLGA Microparticles via Spray Drying Using 3-Fluid Nozzle

    Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 1969-1977 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

    Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

    Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Characterization of PTH-CPP fusion peptides for oral delivery

    Kristensen, Mie, Berthelsen, J. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Parathyroid hormone coupled to cell-penetrating peptides for oral delivery

    Kristensen, Mie & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  18. 2013
  19. Published

    Models to predict intestinal absorption of therapeutic peptides and proteins

    Antunes, F., Andrade, F., Ferreira, D., Nielsen, Hanne Mørck & Sarmento, B., Jan 2013, In: Current Drug Metabolism. 14, 1, p. 4-20 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2011
  21. Published

    Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)

    van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  22. Published

    Development of biodegradable nanocomposite scaffolds for autologous cell therapy

    Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 1 Jan 2011, In: European Cells and Materials. 21, SUPPL.1, 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2010
  24. Published

    Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))

    Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  25. Published

    Issues in Development of Biodrug Delivery Systems

    Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  26. 2009
  27. Published

    Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems

    Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  28. 2007
  29. Published

    Bioinformatic and experimental analysis of the secondary structure of amelogenin

    Vilhjalmsson, B., Rasmussen, Anne, Fabi, B., van de Weert, Marco, Hamelryck, Thomas Wim & Lemoult, S., 1 Nov 2007, In: European Cells and Materials. 14, SUPPL.2, 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2000
  32. Published

    Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques

    van de Weert, Marco, Van 'T Hof, R., Van Der Weerd, J., Heeren, R. M. A., Posthuma, G., Hennink, W. E. & Crommelin, D. J. A., 31 Jul 2000, In: Journal of Controlled Release. 68, 1, p. 31-40 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 1996
  34. Published

    Drug delivery studies in Caco-2 monolayers V. Ethyl glucoside esters as a novel type of absorption enhancers

    Nielsen, Hanne Mørck, Brøndsted, H., Frøkjær, Sven & Hovgaard, L., 1 Mar 1996, In: S.T.P. Pharma Sciences. 6, 2, p. 157-161 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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