Drug Delivery and Biophysics of Biopharmaceuticals

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  1. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing

    Liu, X., Nielsen, L. H., Klodzinska, S. N., Nielsen, Hanne Mørck, Qu, H., Christensen, L. P., Rantanen, Jukka & Yang, Mingshi, Feb 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 123, p. 42-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

    Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

    Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement

    Malekkhaiat Häffner, S., Nyström, L., Browning, K. L., Nielsen, Hanne Mørck, Strömstedt, A. A., van der Plas, Mariena J.A., Schmidtchen, A. & Malmsten, Martin, 1 May 2019, In: A C S Applied Materials and Interfaces. 11, 17, p. 15389-15400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Sucrose modulates insulin amyloid-like fibril formation: effect on the aggregation mechanism and fibril morphology

    Marasini, C., Foderà, Vito & Vestergaard, Bente, 2017, In: RSC Advances. 7, p. 10487-10493

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

    Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

    Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

    Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

    Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Physical and barrier changes in gastrointestinal mucus induced by the permeation enhancer sodium 8-[(2-hydroxybenzoyl)amino]octanoate (SNAC)

    Mortensen, Janni Støvring, Bohr, S. S. R., Rønholt, Stine, Hatzakis, Nikos, Saaby, Lasse & Nielsen, Hanne Mørck, 2022, In: Journal of Controlled Release. 352, p. 163-178 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Preanalytical Stability of Flucloxacillin, Piperacillin, Tazobactam, Meropenem, Cefalexin, Cefazolin, and Ceftazidime in Therapeutic Drug Monitoring: A Structured Review

    Mortensen, Janni Støvring, Jensen, B. P. & Doogue, M., 2022, In: Therapeutic Drug Monitoring. 44, 6, p. 709-719

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Preanalytical Stability of Piperacillin, Tazobactam, Meropenem, and Ceftazidime in Plasma and Whole Blood Using Liquid Chromatography-Tandem Mass Spectrometry

    Mortensen, Janni Støvring, Jensen, B. P., Zhang, M. & Doogue, M., Aug 2019, In: Therapeutic Drug Monitoring. 41, 4, p. 538-543

    Research output: Contribution to journal › Letter › Research › peer-review

  14. Published

    Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

    Mortensen, Janni Støvring, Bohr, S. S. R., Krog, Lasse Skjoldborg, Bøtker, Johan Peter, Kapousidou, V., Saaby, Lasse, Hatzakis, Nikos, Nielsen, Hanne Mørck, Nguyen, Duc Ninh & Rønholt, Stine, 2024, In: Scientific Reports. 14, 1, 17 p., 7665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Overcoming the Mucus barrier

    Mortensen, Janni Støvring, Stie, Mai Bay, Rønholt, Stine & Nielsen, Hanne Mørck, 2021, Organelle and Molecular Targeting. Milane, L. S. & Amiji, M. M. (eds.). CRC Press, p. 355-379 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Effects of prophylactic antibiotics administration on barrier properties of intestinal mucosa and mucus from preterm born piglets

    Mortensen, Janni Støvring, Nguyen, Duc Ninh, Nielsen, Hanne Mørck & Rønholt, Stine, 2023, In: Drug Delivery and Translational Research. 13, p. 1456–1469

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

    Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Drug delivery studies in Caco-2 monolayers V. Ethyl glucoside esters as a novel type of absorption enhancers

    Nielsen, Hanne Mørck, Brøndsted, H., Frøkjær, Sven & Hovgaard, L., 1 Mar 1996, In: S.T.P. Pharma Sciences. 6, 2, p. 157-161 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Epithelial permeation and absorption mechanisms of biopharmaceuticals

    Nielsen, Hanne Mørck, 1 Oct 2014, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies. Springer US, Vol. 9781461495246. p. 99-122 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems

    Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles

    Nielsen, Hanne Mørck, 2018, In: Advanced Drug Delivery Reviews.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing

    Nielsen, Hanne Mørck, 2018, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis

    Nosrati, Z., Bergamo, M., Rodriguez-Rodriguez, C., Saatchi, K. & Hafeli, U. O., 2020, In: Arthritis Research & Therapy. 22, 1, 16 p., 281.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Simultaneous SPECT imaging with 123I and 125I - a practical approach to assessing a drug and its carrier at the same time with dual imaging

    Nosrati, Z., Esquinas, P. L., Rodríguez-Rodríguez, C., Tran, T., Maharaj, A., Saatchi, K. & Häfeli, U. O., 2021, In: International Journal of Pharmaceutics. 606, 13 p., 120884.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))

    Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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