Drug Delivery and Biophysics of Biopharmaceuticals

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  1. Published

    EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

    Eissa, N. G., Sayers, E. J., Birch, D., Patel, S. G., Tsai, Y. H., Nielsen, Hanne Mørck & Jones, A. T., 8 Jan 2020, In: Biochemical Journal. 477, 1, p. 45-60 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Early Stage Alpha-Synuclein Amyloid Fibrils are Reservoirs of Membrane-Binding Species

    Skamris, T., Marasini, C., Madsen, Kenneth Lindegaard, Foderà, Vito & Vestergaard, Bente, 2019, In: Scientific Reports. 9, p. 1-11 11 p., 1733.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Editorial: Microbe-nanoparticle interactions: a mechanistic approach

    Kumari, M., Klodzinska, S. N. & Chifiriuc, M. C., 2023, In: Frontiers in Microbiology. 14, 2 p., 1273364.

    Research output: Contribution to journal › Editorial › Research › peer-review

  4. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

    Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

    Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

    Fonte, P., Andrade, F., Azevedo, C., Pinto, J., Seabra, V., van de Weert, Marco, Reis, S. & Sarmento, B., 2016, In: Pharmaceutical Research. 33, 11, p. 2777–2793

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Effect of thermal and shear stresses in the spray drying process on the stability of siRNA dry powders

    Wu, J., Wu, L., Wan, F., Rantanen, Jukka, Cun, D. & Yang, Mingshi, 2019, In: International Journal of Pharmaceutics. 566, p. 32-39 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effects of prophylactic antibiotics administration on barrier properties of intestinal mucosa and mucus from preterm born piglets

    Mortensen, Janni Støvring, Nguyen, Duc Ninh, Nielsen, Hanne Mørck & Rønholt, Stine, 2023, In: Drug Delivery and Translational Research. 13, p. 1456–1469

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Electrosprayed Poly-butyl-succinate microparticles for sustained release of Ciprofloxacin as an antimicrobial delivery system

    Foderà, Vito, Terracina, F., Catania, V., Sciré, S., Schillaci, D. & Licciardi, M., 2024, In: Powder Technology. 432, 10 p., 119152.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Encapsulation in oleyl-modified hyaluronic acid nanogels substantially improves the clinical potential of the antimicrobial peptides SAAP-148 and Ab-Cath

    van Gent, M. E., Klodzinska, S. N., Drijfhout, J. W., Nielsen, Hanne Mørck & Nibbering, P. H., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 254-261

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Encapsulation into hyaluronic acid-based nanogels improves the selectivity index of the snake cathelicidin Ab-Cath

    van Gent, M. E., Kłodzińska, S. N., Severin, M., Ali, M., van Doodewaerd, B. R., Bos, E., Koning, R. I., Drijfhout, J. W., Nielsen, Hanne Mørck & Nibbering, P. H., 2023, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 52, 11 p., 102694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Encapsulation of SAAP-148 in Octenyl Succinic Anhydride-Modified Hyaluronic Acid Nanogels for Treatment of Skin Wound Infections

    van Gent, M. E., van Baaren, T., Kłodzińska, S. N., Ali, M., Dolezal, N., van Doodewaerd, B. R., Bos, E., de Waal, A. M., Koning, R. I., Drijfhout, J. W., Nielsen, Hanne Mørck & Nibbering, P. H., 2023, In: Pharmaceutics. 15, 2, 20 p., 429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Epithelial permeation and absorption mechanisms of biopharmaceuticals

    Nielsen, Hanne Mørck, 1 Oct 2014, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies. Springer US, Vol. 9781461495246. p. 99-122 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

    Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)

    van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  18. Published

    Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

    Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  19. Published

    Ethanol Controls the Self-Assembly and Mesoscopic Properties of Human Insulin Amyloid Spherulites

    Vetri, V., Piccirilli, F., Krausser, J., Buscarino, G., Łapińska, U., Vestergaard, Bente, Zaccone, A. & Foderà, Vito, 29 Mar 2018, In: The Journal of Physical Chemistry B. 122, 12, p. 3101-3112

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium

    Birch, D., Diedrichsen, Ragna Guldsmed, Christophersen, P. C., Mu, Huiling & Nielsen, Hanne Mørck, Jun 2018, In: European Journal of Pharmaceutical Sciences. 118, p. 144-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Evolving biosimilar clinical requirements: A qualitative interview study with industry experts and European national medicines agency regulators

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, van de Weert, Marco, De Bruin, M. L. (., Hoogland, H., Minssen, Timo & Almarsdóttir, Anna Birna, 2021, In: BioDrugs. 35, p. 351-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

    Rønholt, Stine, Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, Hanne Mørck, 1 Jan 2019, In: Drug Delivery. 26, 1, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Flexibility defines structure in crystals of amphiphilic DNA nanostars

    Brady, R. A., Kaufhold, W. T., Brooks, N. J., Foderà, Vito & Di Michele, L., 2019, In: Journal of Physics: Condensed Matter. 31, 7, 11 p., 0704003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

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