Drug Delivery and Biophysics of Biopharmaceuticals

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  1. Published

    Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

    Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration

    Agnoletti, M., Rodríguez-Rodríguez, C., Klodzinska, S. N., Esposito, T., Saatchi, K., Nielsen, Hanne Mørck & Häfeli, U. O., 2020, In: ACS Nano. 14, p. 6693-6706

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Peptide-Membrane Interactions Monitored by Fluorescence Lifetime Imaging: A Study Case of Transportan 10

    Anselmo, S., Sancataldo, G., Nielsen, Hanne Mørck, Foderà, Vito & Vetri, V., 2021, In: Langmuir. 37, 44, p. 13148-13159

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    α-casein micelles-membranes interaction: Flower-like lipid protein coaggregates formation

    Anselmo, S., Sancataldo, G., Foderà, Vito & Vetri, V., 2022, In: Biochimica et Biophysica Acta - General Subjects. 1866, 10, 11 p., 130196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Sustainable soy protein microsponges for efficient removal of lead (II) from aqueous environments

    Anselmo, S., Avola, T., Kalouta, Kleopatra, Cataldo, S., Sancataldo, G., Muratore, N., Foderà, Vito, Vetri, V. & Pettignano, A., 2023, In: International Journal of Biological Macromolecules. 239, 14 p., 124276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency

    Antonino, R. S. C. M. Q., Ruggiero, M., Song, Z., Nascimento, T. L., Lima, E. M., Bohr, A., Knopp, Matthias Manne & Löbmann, Korbinian, 2019, In: International Journal of Pharmaceutics: X. 1, 7 p., 100026.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Models to predict intestinal absorption of therapeutic peptides and proteins

    Antunes, F., Andrade, F., Ferreira, D., Nielsen, Hanne Mørck & Sarmento, B., Jan 2013, In: Current Drug Metabolism. 14, 1, p. 4-20 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Cell-Penetrating Peptides as Tools to Facilitate Oral Delivery of Biopharmaceuticals

    Asgreen, Camilla Jantzen, Fredholt, Freja, Nielsen, Hanne Mørck & Kristensen, Mie, 2023, Cell-Penetrating Peptides: Design, Development and Applications. Oba, M. & Demizu, Y. (eds.). Wiley-VCH, p. 331-354

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  9. Published

    Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

    Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators

    Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2019, In: International Journal of Antimicrobial Agents. 53, p. 868-872 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics

    Baker, K. R., Jana, B., Hansen, A. M., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2 Jul 2019, In: Frontiers in Cellular and Infection Microbiology. 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin

    Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, Henrik & Nielsen, Hanne Mørck, 2023, In: Pharmaceutics. 15, 6, 15 p., 1672.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium

    Birch, D., Diedrichsen, Ragna Guldsmed, Christophersen, P. C., Mu, Huiling & Nielsen, Hanne Mørck, Jun 2018, In: European Journal of Pharmaceutical Sciences. 118, p. 144-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Direct observations of drug nanocarrier interactions and mobility within biological interfaces

    Bohr, S. S. R., Streck, S., Pinholt, H., Wan, F., Mcdowell, A., Nielsen, Hanne Mørck & Hatzakis, Nikos, 2022, In: Biophysical Journal. 121, 3, p. 72a-73a 2 p., 355-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting

    Bohrmann, L., Burghardt, T., Rodríguez-Rodríguez, C., Herth, Matthias Manfred, Saatchi, K. & Häfeli, U. O., 2023, In: ACS Omega. 8, 12, p. 11003-11020

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Aptamers used for molecular imaging and theranostics: recent developments

    Bohrmann, L., Burghardt, T., Haynes, C., Saatchi, K. & Häfeli, U. O., 2022, In: Theranostics. 12, 9, p. 4010-4050

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Development of a 99mTc-labeled tetrazine for pretargeted SPECT imaging using an alendronic acid-based bone targeting model

    Bohrmann, L., Poulie, Christian Bernard Matthijs, Rodríguez-Rodríguez, C., Karagiozov, S., Saatchi, K., Herth, Matthias Manfred & Häfeli, U. O., 2024, In: PLoS ONE. 19, 4, 18 p., e0300466.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Interaction with prefibrillar species and amyloid-like fibrils changes the stiffness of lipid bilayers

    Borro, B. C., Parolini, L., Cicuta, P., Foderà, Vito & Di Michele, L., 25 Oct 2017, In: Physical chemistry chemical physics : PCCP. 19, 41, p. 27930-27934 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra

    Bortolotti, A., Wong, Y. H., Korsholm, S. S., Bahring, N. H. B., Bobone, S., Tayyab, S., van de Weert, Marco & Stella, L., 2016, In: RSC Advances. 6, 114, p. 112870-112876 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Amphiphilic-DNA Platform for the Design of Crystalline Frameworks with Programmable Structure and Functionality

    Brady, R. A., Brooks, N. J., Foderà, Vito, Cicuta, P. & Di Michele, L., 14 Nov 2018, In: Journal of the American Chemical Society. 140, 45, p. 15384-15392

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Flexibility defines structure in crystals of amphiphilic DNA nanostars

    Brady, R. A., Kaufhold, W. T., Brooks, N. J., Foderà, Vito & Di Michele, L., 2019, In: Journal of Physics: Condensed Matter. 31, 7, 11 p., 0704003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Drug delivery studies in Caco-2 monolayers. III. Intestinal transport of various vasopressin analogues in the presence of lysophosphatidylcholine

    Brøndsted, H., Nielsen, Hanne Mørck & Hovgaard, L., 14 Feb 1995, In: International Journal of Pharmaceutics. 114, 2, p. 151-157 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Disentangling the role of solvent polarity and protein solvation in folding and self-assembly of α-lactalbumin

    Bucciarelli, S., Sayedi, E. S., Osella, S., Trzaskowski, B., Vissing, K. J., Vestergaard, Bente & Foderà, Vito, 2020, In: Journal of Colloid and Interface Science. 561, p. 749-761 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Optical catapulting of microspheres in mucus models-toward overcoming the mucus biobarrier

    Bunea, A., Chouliara, M., Rønholt, Stine, Banas, A. R., Engay, E. L. & Gluckstad, J., Mar 2019, In: Journal of Biomedical Optics. 24, 3, 10 p., 035001.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Membrane interactions in drug delivery: Model cell membranes and orthogonal techniques

    Bunea, A., Rønholt, Stine, Taboryski, R. & Nielsen, Hanne Mørck, 2020, In: Advances in Colloid and Interface Science. 281, 15 p., 102177.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

    Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

    Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Mucus as a Barrier to Drug Delivery: Understanding and Mimicking the Barrier Properties

    Bøgh, M. & Nielsen, Hanne Mørck, Mar 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 3, p. 179-186 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Ion-Mediated Morphological Diversity in Protein Amyloid Systems

    Chaaban, Hussein Forsberg, Vallooran, J. J., van de Weert, Marco & Foderà, Vito, 2022, In: Journal of Physical Chemistry Letters. 13, 16, p. 3586-3593

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Development of an immunosuppressed orthotopic hepatocellular carcinoma rat model for the evaluation of chemo- and radioembolization therapies

    Charles, L., Sekar, S., Osooly, M., Javed, S., Williams, K. C., Welch, I., Barta, I., Saatchi, K. & Häfeli, U. O., 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 196, 9 p., 114180.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR

    Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Guidance for pediatric use in prescription information for novel medicinal products in the EU and the US

    Christiansen, H., De Bruin, M. L., Frøkjær, Sven & Hallgreen, Christine Erikstrup, 2022, In: PLoS ONE. 17, 4, 19 p., e0266353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Formulation Strategies and Particle Engineering Technologies for Pulmonary Delivery of Biopharmaceuticals

    Cun, D., Wan, F. & Yang, Mingshi, 2015, In: Current Pharmaceutical Design. 21, 19, p. 2599-2610 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Thioflavin T templates amyloid β(1-40) conformation and aggregation pathway

    Di Carlo, M. G., Minicozzi, V., Foderà, Vito, Militello, V., Vetri, V., Morante, S. & Leone, M., Nov 2015, In: Biophysical Chemistry. 206, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Stereochemistry and Intermolecular Interactions Influence Carrier Peptide-Mediated Insulin Delivery

    Diedrichsen, Ragna Guldsmed, Tuelung, P. S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Molecular Pharmaceutics. 20, 2, p. 1202–1212

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Carrier peptide interactions with liposome membranes induce reversible clustering by surface adsorption and shape deformation

    Diedrichsen, Ragna Guldsmed, Vetri, V., Prévost, S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Journal of Colloid and Interface Science. 650, Part B, p. 1821-1832

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

    Diedrichsen, Ragna Guldsmed, Rønholt, Stine, Werner, U., Besenius, M., Leberer, E., Kristensen, Mie & Nielsen, Hanne Mørck, 2021, In: Journal of Controlled Release. 338, p. 8-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    A qualitative study of biosimilar manufacturer and regulator perceptions on intellectual property and abbreviated approval pathways

    Druedahl, Louise C., Almarsdóttir, Anna Birna, Kälvemark Sporrong, Sofia, De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kesselheim, A. S. & Sarpatwari, A., 2020, In: Nature Biotechnology. 38, 11, p. 1253-1256 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Evolving biosimilar clinical requirements: A qualitative interview study with industry experts and European national medicines agency regulators

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, van de Weert, Marco, De Bruin, M. L. (., Hoogland, H., Minssen, Timo & Almarsdóttir, Anna Birna, 2021, In: BioDrugs. 35, p. 351-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Interchangeability of biosimilars: A study of expert views and visions regarding the science and substitution

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, Minssen, Timo, Hoogland, H., De Bruin, M. L. (., van de Weert, Marco & Almarsdóttir, Anna Birna, 2022, In: PLOS One. 17, 1, p. 1-13 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Medicines authority regulators and industry perspectives on the European regulation of biosimilars

    Druedahl, Louise C., De Bruin, M. L. (., van de Weert, Marco, Minssen, Timo, Hoogland, H. & Almarsdóttir, Anna Birna, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  47. Published

    MEDICINES AUTHORITY REGULATOR AND INDUSTRY PERCEPTIONS OF BIOSIMILAR INTERCHANGEABILITY

    Druedahl, Louise C., De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kälvemark Sporrong, Sofia & Almarsdóttir, Anna Birna, Dec 2019, p. E45-E46.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  48. Published

    EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

    Eissa, N. G., Sayers, E. J., Birch, D., Patel, S. G., Tsai, Y. H., Nielsen, Hanne Mørck & Jones, A. T., 8 Jan 2020, In: Biochemical Journal. 477, 1, p. 45-60 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018)

    Esposito, T. V. F., Rodríguez-Rodríguez, C., Blackadar, C., Haney, E. F., Pletzer, D., Hancock, R. E. W., Saatchi, K. & Häfeli, U. O., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 179, p. 11-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform

    Esposito, T. V. F., Stütz, H., Rodríguez-Rodríguez, C., Bergamo, M., Charles, L., Geczy, R., Blackadar, C., Kutter, Jörg P., Saatchi, K. & Häfeli, U. O., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2823–2834

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  52. Published

    Mapping the Diversity of Protein Aggregates

    Foderà, Vito, 2019, p. S87-S87.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  53. Published

    Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures

    Foderà, Vito, Vetri, V., Wind, T. S., Noppe, W., Cornett, Claus, Donald, A. M., Morozova-Roche, L. A. & Vestergaard, Bente, 18 Sep 2014, In: Journal of Physical Chemistry Letters. 5, 18, p. 3254-3258 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization

    Fonte, P., Araújo, F., Seabra, V., Reis, S., van de Weert, Marco & Sarmento, B., 30 Dec 2015, In: International Journal of Pharmaceutics. 496, 2, p. 850-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

    Fonte, P., Andrade, F., Azevedo, C., Pinto, J., Seabra, V., van de Weert, Marco, Reis, S. & Sarmento, B., 2016, In: Pharmaceutical Research. 33, 11, p. 2777–2793

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

    Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

    Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Conformational Transitions upon Maturation Rule Surface and pH-Responsiveness of alpha-Lactalbumin Microparticulates

    Galparsoro, D. F., Zhou, X., Jaaloul, A., Piccirilli, F., Vetri, V. & Foderà, Vito, 2021, In: ACS Applied Bio Materials. 4, 2, p. 1876-1887

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Conformational heterogeneity of amyloid protein condensates

    Galparsoro, D. F., de Luca, G., Sancataldo, G., Vetri, V. & Foderà, Vito, 2021, In: European Biophysics Journal. 50, SUPPL 1, p. 90-90 O-159.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  61. Published

    Controlled self-assembly of alpha-lactalbumin microparticles for pH-responsive release of protein material

    Galparsoro, D. F., Vetri, V. & Foderà, Vito, 2021, In: European Biophysics Journal. 50, SUPPL 1, p. 122-122

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  62. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Use of fluorescent probes for ROS to tease apart Type I and Type II photochemical pathways in photodynamic therapy

    Garcia-Diaz, M., Huang, Y. & Hamblin, M. R., 15 Oct 2016, In: Methods. 109, p. 158-166 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles

    García-Díaz, M., Birch, D., Wan, F. & Nielsen, Hanne Mørck, Jan 2018, In: Advanced Drug Delivery Reviews. 124, p. 107-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Chloroform compatible, thiol-ene based replica molded micro chemical devices as an alternative to glass microfluidic chips

    Geczy, R., Sticker, Drago, Bovet, N., Hafeli, U. O. & Kutter, Jörg P., 2019, In: Lab on a Chip. 5, p. 798-806 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Antimicrobial activity of GN peptides and their mode of action

    Godballe, T., Mojsoska, B., Nielsen, Hanne Mørck & Jenssen, H., 13 Dec 2015, In: Biopolymers. 106, 2, p. 172–183 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Comparative assessment of in vitro/in vivo performances of orodispersible electrospun and casting films containing rizatriptan benzoate

    Guo, X., Cun, D., Wan, F., Bera, H., Song, Q., Tian, X., Chen, Y., Rantanen, Jukka & Yang, Mingshi, 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 283-289 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Co-delivery of resveratrol and docetaxel via polymeric micelles to improve the treatment of drug-resistant tumors

    Guo, X., Zhao, Z., Chen, D., Qiao, M., Wan, F., Cun, D., Sun, Y. & Yang, Mingshi, 2019, In: Asian Journal of Pharmaceutical Sciences. 14, 1, p. 78-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    α-Lactalbumin-Based Nanofiber Dressings Improve Burn Wound Healing and Reduce Scarring

    Guo, X., Liu, Y., Bera, H., Zhang, H., Chen, Y., Cun, D., Foderà, Vito & Yang, Mingshi, 2020, In: A C S Applied Materials and Interfaces. 12, 41, p. 45702-45713 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Microfluidic approaches for the production of monodisperse, superparamagnetic microspheres in the low micrometer size range

    Géczy, R., Agnoletti, M., Hansen, M. F., Kutter, Jörg P., Saatchi, K. & Häfeli, U. O., 1 Feb 2019, In: Journal of Magnetism and Magnetic Materials. 471, p. 286-293

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Nanotechnology for photodynamic therapy: a perspective from the Laboratory of Dr. Michael R. Hamblin in the Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School

    Hamblin, M. R., Chiang, L. Y., Lakshmanan, S., Huang, Y., Garcia-Diaz, M., Karimi, M., de Souza Rastelli, A. N. & Chandran, R., Aug 2015, In: Nanotechnology Reviews. 4, 4, p. 359-372 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Assessment of mucoadhesion using small deformation rheology revisited

    Rønholt, Stine, Vissing, K. J. & Nielsen, Hanne Mørck, Apr 2017, In: Nordic Rheology Society Annual Transactions. 25, p. 63 7 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  73. Published

    Animal models for evaluation of oral delivery of biopharmaceuticals

    Rønholt, Stine, Nielsen, L. H. & Nielsen, Hanne Mørck, Dec 2017, In: Journal of Controlled Release. 268, p. 57-71 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  74. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

    Rønholt, Stine, Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, Hanne Mørck, 1 Jan 2019, In: Drug Delivery. 26, 1, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

    Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

    Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Shuffled lipidation pattern and degree of lipidation determines the membrane interaction behavior of a linear cationic membrane-active peptide

    Hedegaard, S. F., Bruhn, D. S., Khandelia, H., Cardenas, M. & Nielsen, Hanne Mørck, 2020, In: Journal of Colloid and Interface Science. 578, p. 584-597 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties

    Nagstrup, Anne Hedengran, Freiberg, Josefine, Hansen, Pernille May, Jacobsen, Jette, Larsen, Susan Weng, Rønholt, Stine, Freude, Kristine, Boix‐lemonche, G., Petrovski, G., Heegaard, Steffen & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Preferential interactions and the effect of protein PEGylation

    Holm, L. S., Thulstrup, Peter Waaben, Kasimova, M. R. & van de Weert, Marco, 2015, In: PLOS ONE. 10, 7, 18 p., e0133584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Drug delivery studies in Caco-2 monolayers. II. Absorption enhancer effects of lysophosphatidylcholines

    Hovgaard, L., Brøndsted, H. & Nielsen, Hanne Mørck, 14 Feb 1995, In: International Journal of Pharmaceutics. 114, 2, p. 141-149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

    Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Synthesis of carbon quantum dot-poly lactic-co-glycolic acid hybrid nanoparticles for chemo-photothermal therapy against bacterial biofilms

    Huang, Z., Zhou, T., Yuan, Y., Klodziska, S. N., Zheng, T., Sternberg, C., Nielsen, Hanne Mørck, Sun, Y. & Wan, F., 2020, In: Journal of Colloid and Interface Science. 577, p. 66-74 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections

    Huang, Z., Klodzinska, S. N., Wan, F. & Nielsen, Hanne Mørck, 2021, In: Drug Delivery and Translational Research. 11, p. 1634–1654

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

    Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin

    Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions

    Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

    Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

    Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Issues in Development of Biodrug Delivery Systems

    Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  96. Published

    Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

    Kabedev, A., Zhuo, Xuezhi, Leng, D., Foderà, Vito, Zhao, M., Larsson, P., Bergström, C. A. S. & Löbmann, Korbinian, 2022, In: Molecular Pharmaceutics. 19, 11, p. 3922–3933

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Classification of vaccines

    Kallerup, R. S. & Foged, Camilla, 2015, Subunit vaccine delivery. Foged, C., Rades, T., Perrie, Y. & Hooks, S. (eds.). Springer, p. 15-29 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  98. Published

    Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

    Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Bioimaging and Biodistribution of the Metal‐Ion‐Controlled Self‐Assembly of PYY3–36 Studied by SPECT/CT

    Kalomoiri, Panagiota, Rodríguez‐rodríguez, C., Sørensen, K. K., Bergamo, M., Saatchi, K., Häfeli, U. O. & Jensen, Knud Jørgen, 2020, In: ChemBioChem. 21, 23, p. 3338-3343 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

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