19 July 2022

Esben Trabjerg is now Tenure track Assistant Professor

Assistant Professor​ Esben Trabjerg
Assistant Professor​ Esben Trabjerg.

The new Tenure track Assistant Professor tells about his focus as a researcher and his background: ​​​​

“My main focus as a researcher here at the department is to develop and apply mass spectrometric methods for the 

characterization of proteins and biopharmaceutical. I am very interested in the analysis of the higher-order structure of proteins and biopharmaceuticals, which I characterize by a combination of XL-MS and HDX-MS. Furthermore, I am one of the main lectures on the bachelor course “Evaluation of Pharmaceutical Substances".

I did my PhD as an industrial PhD candidate at H. Lundbeck A/S in collaboration with the Protein Analysis Group from 2014-2017. Here, I investigated the interaction between the Sortilin receptor, a receptor implicated in dementia, and its endogenous binding partners, as well as modulating antibodies. The mapping of the interaction sites were predominantly performed by hydrogen/deuterium exchange mass spectrometry (HDX-MS).

After finalizing my PhD, I worked to years (2018-2019) as a postdoc in the Lab of Ruedi Aebersold and Paola Picotti at ETH Zürich. The focus of my research at ETH was to investigate the interaction between the neonatal Fc receptor and IgG1 antibodies by a combination of cross-linking mass spectrometry (XL-MS) and HDX-MS. An interaction, which is responsible for the remarkably long half-life IgG1 antibodies have in the human body of up to 3 weeks.

Since the spring of 2020, I have been employed as Assistant Professor in the Protein Analysis Group.

I like to spend my spare time with my family and friends, and when time allows, I like to play football."