Fabrication of a microfluidic cell made of thiol-ene for microarray applications
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Fabrication of a microfluidic cell made of thiol-ene for microarray applications. / Sola, Laura; Gagni, Paola; Jensen, Thomas G.; Zilio, Caterina; Cretich, Marina; Kutter, Jörg P.; Chiari, Marcella.
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. p. 1719-1721.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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TY - GEN
T1 - Fabrication of a microfluidic cell made of thiol-ene for microarray applications
AU - Sola, Laura
AU - Gagni, Paola
AU - Jensen, Thomas G.
AU - Zilio, Caterina
AU - Cretich, Marina
AU - Kutter, Jörg P.
AU - Chiari, Marcella
PY - 2014
Y1 - 2014
N2 - We report on the fabrication of a microfluidic cell completely made of thiol-ene for microarray applications. To overcome the issues related to the hydrophobic nature of the thiol-ene material we have also introduced a new polymeric coating based of N, N-dimethylacrylamide (DMA) which is able to reduce the material hydrophobicity, to avoid aspecific protein binding and, thanks to the functional monomer propinyl mathacrylate, it is able to bind, in an oriented way, azido modified biomolecules.
AB - We report on the fabrication of a microfluidic cell completely made of thiol-ene for microarray applications. To overcome the issues related to the hydrophobic nature of the thiol-ene material we have also introduced a new polymeric coating based of N, N-dimethylacrylamide (DMA) which is able to reduce the material hydrophobicity, to avoid aspecific protein binding and, thanks to the functional monomer propinyl mathacrylate, it is able to bind, in an oriented way, azido modified biomolecules.
KW - Antibody oriented immobilization
KW - Coatings
KW - Microarray
KW - Microfluidics
KW - Thiol-ene
UR - http://www.scopus.com/inward/record.url?scp=84941711095&partnerID=8YFLogxK
M3 - Article in proceedings
AN - SCOPUS:84941711095
SP - 1719
EP - 1721
BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PB - Chemical and Biological Microsystems Society
T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Y2 - 26 October 2014 through 30 October 2014
ER -
ID: 173280272