Research areas

  1. Published

    Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus

    Schou, J., Kristiansen, Uffe, Stafford, G. I., van Heerden, F. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1217

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  2. Published

    Phylogeny as selection tool for exploring CNS-activity in the Amaryllidaceae

    Rønsted, Nina, Bay-Smidt, M. G. K., Krydsfeldt, K., van Staden, J., Stafford, G. I. & Jäger, A. K., Aug 2010, In: Planta Medica. 76, 12, p. 1178

    Research output: Contribution to journalConference articleResearchpeer-review

  3. Published

    Phytochemical profile and in vitro activities of Capsella bursa-pastoris L. extracts

    Grosso, C., Vinholes, J., Goncalves, R., Jäger, A., Valentao, P. & Andrade, P., Aug 2010, In: Planta Medica. 76, 12, p. 1239

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  4. Published

    The effect of structural characteristics of Lycopodane-type alkaloids on their acetylcholinesterase inhibitory activity in silico

    Halldorsdottir, E., Jaroszewski, J. W. & Olafsdottir, E., Aug 2010, In: Planta Medica. 76, 12, p. 1212

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  5. Published

    The pharmacophore of thapsigargin

    Christensen, Søren Brøgger, Skytte, D. M., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M. & Møller, J. V., Aug 2010, In: Planta Medica. 76, 12, p. 1187

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures

    Suñol, C., Babot, Z., Cristòfol, R., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, Sep 2010, In: Neurochemical Research. 35, 9, p. 1384-1390 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Application of Q2MM to stereoselective reactions

    Nilsson Lill, S. O., Forbes, A., Donoghue, P., Verdolino, V., Wiest, O., Rydberg, P. & Norrby, P., Sep 2010, In: Current Organic Chemistry. 14, 15, p. 1629-1645

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Direct interaction between CD91 and C1q

    Duus, K., Hansen, E. W., Tacnet, P., Frachet, P., Arlaud, G. J., Thielens, N. M. & Houen, G., 1 Sep 2010, In: FEBS Journal. 277, 17, p. 3526-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    EASL clinical practice guidelines on the management of asites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis

    Pere, G., Angeli, P., Lenz, K., Søren, M., Moore, K., Moreau, R., Merkel, C., Larsen, H. R., Bernardi, M., Garcia-Tsao, G. & Hayes, P., 1 Sep 2010, In: Journal of Hepatology. 53, 3, p. 397-417 30 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  10. Published

    Zinc ions bind to and inhibit activated protein C

    Zhu, T., Ubhayasekera, W., Nickolaus, N., Sun, W., Tingsborg, S., Mowbray, S. L. & Schedin-Weiss, S., 1 Sep 2010, In: Thrombosis and Haemostasis. 104, 3, p. 544-553

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands

    Krogsgaard-Larsen, N., Jensen, Anders A. & Kehler, J., 15 Sep 2010, In: Bioorganic & Medicinal Chemistry Letters. 20, 18, p. 5431-5433

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae

    Mellergaard Larsen, M., Adsersen, A., Davis, A. P., Lledó, M. D., Jäger, A. K. & Rønsted, Nina, Oct 2010, In: Biochemical Systematics and Ecology. 38, 5, p. 1026-1034

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Conformational changes and ligand recognition of Escherichia coli D-xylose binding protein revealed

    Sooriyaarachchi, S., Ubhayasekera, W., Park, C. & Mowbray, S. L., 1 Oct 2010, In: Journal of Molecular Biology. 402, 4, p. 657-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Small angle X-ray scattering studies of blood coagulation factor VII and antibodies at high concentration

    Mosbæk, C. R., 12 Oct 2010, København: Det Farmaceutiske Fakultet. 141 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published

    Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

    Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, Karla Andrea, Johansen, Tommy Nørskov, Nielsen, Birgitte, Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 14 Oct 2010, In: Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, K. A., Ringkjøbing-Elema, M., Müllertz, A., Bond, A. & Rantanen, J., 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

    Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  19. Published

    Insights into the ultrastructure of human intestinal fluids in the fed state by electron microscopy analysis

    Mullertz, Anette , Fatouros, D., Smith, J. R., Vertzoni, M. & Rappas, C., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  20. Published

    Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

    Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  21. Published

    Selection of a lipase for development of an in vitro gastric lipid digestion model

    Larsen, A. T., Jensen, L. G., Hansen, K. K. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In: Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Antidepressive lægemidler: nu i 3D

    Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In: Lægemiddelforskning. 2010, p. 25-27

    Research output: Contribution to journalJournal articleCommunication

  24. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, B. & Clausen, Rasmus Prætorius, Dec 2010, In: Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    Kemogenomik: receptoren set fra lægemiddelstoffets synspunkt

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Pedersen, D. S. & Bräuner, Hans, Dec 2010, In: Lægemiddelforskning. 2010, p. 28-30

    Research output: Contribution to journalJournal articleCommunication

  26. Published

    Nu kan forfalskede lægemidler afsløres

    Kesting, J. R., Adsersen, A. & Gudiksen, L., Dec 2010, In: Lægemiddelforskning. 2010, p. 4-6

    Research output: Contribution to journalJournal articleCommunication

  27. Published

    Paracellular tightness and claudin-5 expression is increased in the BCEC/Astrocyte blood-brain barrier model by increasing media buffer capacity during growth

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, Dec 2010, In: The AAPS Journal. 12, 4, p. 759-770

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Planternes slægtskab som skattekort til nye lægemidler

    Rønsted, Nina, Larsen, Birger Brodin, Christensen, Søren Brøgger, Eriksson, A. H. & Jäger, A. K., Dec 2010, In: Lægemiddelforskning. 2010, p. 19-21

    Research output: Contribution to journalJournal articleCommunication

  29. Published

    Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign

    Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  30. Published

    The SMARTCyp cytochrome P450 metabolism prediction server

    Rydberg, P., Gloriam, David E. & Olsen, L., 1 Dec 2010, In: Bioinformatics. 26, 23, p. 2988-2989

    Research output: Contribution to journalLetterResearchpeer-review

  31. Published

    Biologiens låsesmed

    Bräuner, Hans, 2 Dec 2010, In: Universitetsavisen. 2010, 9, p. 22-23

    Research output: Contribution to journalJournal articleCommunication

  32. Published

    Further insight into the roles of the glycans attached to human blood protein C inhibitor

    Sun, W., Parry, S., Ubhayasekera, W., Engström, Å., Dell, A. & Schedin-Weiss, S., 10 Dec 2010, In: Biochemical and Biophysical Research Communications. 403, 2, p. 198-202

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    1,2,3-triazolyl amino acids as AMPA receptor ligands

    Stanley, N. J., Pedersen, D. S., Nielsen, Birgitte, Kvist, T., Mathiesen, Jesper M., Bräuner, Hans, Taylor, D. K. & Abell, A. D., 15 Dec 2010, In: Bioorganic & Medicinal Chemistry Letters. 20, 24, p. 7512-7515

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain

    Hansen, M., 16 Dec 2010, København: Det Farmaceutiske Fakultet. 207 p.

    Research output: Book/ReportPh.D. thesisResearch

  35. Published

    Partial agonists and subunit selectivity at NMDA receptors

    Risgaard, R., Hansen, K. B. & Clausen, Rasmus Prætorius, 17 Dec 2010, In: Chemistry: A European Journal. 16, 47, p. 13910-13918

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Treatment of insulin resistance and obesity by stimulating GLP-1 release

    Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010

    Research output: Patent

  37. Published

    (Eco)teoxicological effects of transformation products: (Not) a research question ?

    Hansen, M., 2011.

    Research output: Working paperResearch

  38. Published

    1H NMR- and HPLC-based metabolomics combined with hyphenated HPLC-SPE-NMR methods for the investigation of herbal remedies and medicinal plants

    Agnolet, S., 2011, København: Det Farmaceutiske Fakultet.

    Research output: Book/ReportPh.D. thesisResearch

  39. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

    Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin

    Jensen, L. B., Petersson, K. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 68-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery

    Garland, S. L. & Gloriam, David E., 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A model on the carbon cycling in Lake Taihu, China

    Weiping, H., Jørgensen, S. E., Fabing, Z., Yonggen, C., Zhixin, H. & Longyuan, Y., 2011, In: Ecological Modelling. 222, 16, p. 2973-2991

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Activities of drug transporters and cytochrome P450s in cultures of primary hepatocytes

    Jacobsen, J. K., 2011, Det Farmaceutiske Fakultet. 122 p.

    Research output: Book/ReportPh.D. thesisResearch

  45. Published

    Adsorption of insulin with varying self-association profiles to a solid Teflon surface-Influence on protein structures, fibrillation tendency and thermal stability

    Jørgensen, Lene, Bennedsen, P., Hoffmann, S. V., Pinholt, C., Krogh, R. L., Jensen, M. G., Hostrup, S. & Burkinksky, J. T., 2011, In: European Journal of Pharmaceutical Sciences. 42, 5, p. 509-516

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Adverse drug reactions following immunization in Danish children: retrospective analysis of spontaneous reports submitted to the Danish Medicines Agency

    Aagaard, L., Hansen, E. W. & Hansen, E. H., 2011, Science against microbial pathogens: communicating current research and technical advances. Méndez-Vilas, A. (ed.). Badajoz: Formatex, Vol. 1. p. 407-413 (Microbiology series; No. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. Published

    Adverse events following immunization in children: retrospective analysis of spontaneous reports over a decade

    Aagaard, L., Hansen, E. W. & Hansen, E. H., 2011, In: European Journal of Clinical Pharmacology. 67, 1, p. 283-288

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Affinity and translocation relationships via hPEPT1 of H-Xaa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs

    Omkvist, D. H., Trangbæk, D. J., Mildon, J., Paine, J. S., Larsen, Birger Brodin, Begtrup, M. & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 2, p. 327-331

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Analysis and environmental concentrations of the herbicide dichlobenil and its main metabolite 2,6-dichlorobenzamide (BAM): a review

    Björklund, B. E., Anskjær, G. G., Hansen, M., Styrishave, Bjarne & Halling-Sørensen, B., 2011, In: Science of the Total Environment. 409, 12, p. 2343-2356

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Analysis of secondary plant metabolites by indirect desorption electrospray ionization imaging mas spectrometry

    Thunig, U. J. C., Hansen, S. H. & Janfelt, Christian, 2011, In: Analytical Chemistry. 83, p. 3256-3259

    Research output: Contribution to journalLetterResearchpeer-review