Marco van de Weert

Marco van de Weert

Associate Professor

ORCID: 0000-0002-8530-6441

Publication year:
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  1. 2021
  2. Published

    Evolving biosimilar clinical requirements: A qualitative interview study with industry experts and European national medicines agency regulators

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, van de Weert, Marco, De Bruin, M. L. (., Hoogland, H., Minssen, Timo & Almarsdóttir, Anna Birna, 2021, In: BioDrugs. 35, p. 351-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2020
  4. Published

    A qualitative study of biosimilar manufacturer and regulator perceptions on intellectual property and abbreviated approval pathways

    Druedahl, Louise C., Almarsdóttir, Anna Birna, Kälvemark Sporrong, Sofia, De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kesselheim, A. S. & Sarpatwari, A., 2020, In: Nature Biotechnology. 38, 11, p. 1253-1256 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2019
  7. Published

    MEDICINES AUTHORITY REGULATOR AND INDUSTRY PERCEPTIONS OF BIOSIMILAR INTERCHANGEABILITY

    Druedahl, Louise C., De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kälvemark Sporrong, Sofia & Almarsdóttir, Anna Birna, Dec 2019, p. E45-E46.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  8. Published

    The dangers of citing papers you did not read or understand

    van de Weert, Marco & Stella, L., 15 Jun 2019, In: Journal of Molecular Structure: THEOCHEM. 1186, p. 102-103 2 p.

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Medicines authority regulators and industry perspectives on the European regulation of biosimilars

    Druedahl, Louise C., De Bruin, M. L. (., van de Weert, Marco, Minssen, Timo, Hoogland, H. & Almarsdóttir, Anna Birna, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  10. 2018
  11. Published

    Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

    von Halling Laier, C., Gibson, B., van de Weert, Marco, Boyd, B. J., Rades, Thomas, Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

    Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 6 Sep 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin

    Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2017
  15. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

    Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions

    Ji, S., Thulstrup, Peter Waaben, Mu, Huiling, Hansen, S. H., van de Weert, Marco, Rantanen, Jukka & Yang, Mingshi, 2017, In: International Journal of Pharmaceutics. 534, 1-2, p. 263-271 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2016
  19. Published

    Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions

    Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

    Esmail Nazari, Z., van de Weert, Marco, Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, Kasper Dyrberg, 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

    Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

    Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme

    Ji, S., Thulstrup, Peter Waaben, Mu, Huiling, Hansen, S. H., van de Weert, Marco, Rantanen, Jukka & Yang, Mingshi, 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 175-182 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

    Fonte, P., Andrade, F., Azevedo, C., Pinto, J., Seabra, V., van de Weert, Marco, Reis, S. & Sarmento, B., 2016, In: Pharmaceutical Research. 33, 11, p. 2777–2793

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

    Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra

    Bortolotti, A., Wong, Y. H., Korsholm, S. S., Bahring, N. H. B., Bobone, S., Tayyab, S., van de Weert, Marco & Stella, L., 2016, In: RSC Advances. 6, 114, p. 112870-112876 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release

    Svagan, A. J., Kusic, A., De Gobba, C., Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2015
  30. Published

    Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization

    Fonte, P., Araújo, F., Seabra, V., Reis, S., van de Weert, Marco & Sarmento, B., 30 Dec 2015, In: International Journal of Pharmaceutics. 496, 2, p. 850-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

    Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, Oct 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  32. Published

    Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

    Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein

    Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Preferential interactions and the effect of protein PEGylation

    Holm, L. S., Thulstrup, Peter Waaben, Kasimova, M. R. & van de Weert, Marco, 2015, In: PLOS ONE. 10, 7, 18 p., e0133584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2014
  37. Published

    A reassessment of synchronous fluorescence in the separation of Trp and Tyr contributions in protein emission and in the determination of conformational changes

    Bobone, S., van de Weert, Marco & Stella, L., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 68-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Fluorescence spectroscopy and binding: Getting it right

    Stella, L., van de Weert, Marco, Burrows, H. D. & Fausto, R., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 1-3 3 p.

    Research output: Contribution to journal › Editorial › Research

  39. Published

    Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin

    Weisbjerg, P. L. G., Caspersen, M. B., Cook, K. & van de Weert, Marco, 1 Dec 2014, In: Journal of Pharmaceutical Sciences. 104, 2, p. 548-556 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

    Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

    Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. 2013
  44. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

    Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The challenges in and importance of analysing protein structure and physical stability in complex formulations

    Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements

    Neergaard, M. S., Kalonia, D. S., Parshad, H., Nielsen, A., Møller, E. H., van de Weert, Marco & Nielsen, A. D., 26 Apr 2013, In: European Journal of Pharmaceutical Sciences. 49, 3, p. 400-410 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  48. Published

    Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30)

    Jensen, M. H., Wahlund, P., Toft, K. N., Jacobsen, J. K., Steensgaard, D. B., van de Weert, Marco, Havelund, S. & Vestergaard, Bente, 15 Jan 2013, In: Biochemistry. 52, 2, p. 282-94 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Characterization of Therapeutic Peptides and Proteins

    van de Weert, Marco & Arvinte, T., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 49-78

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  50. Published

    Physical Instability of Peptides and Proteins

    van de Weert, Marco & Randolph, T. W., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 107-130

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  51. 2012
  52. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Forced degradation of therapeutic proteins

    Hawe, A., Wiggenhorn, M., van de Weert, Marco, Garbe, J. H. O., Mahler, H. & Jiskoot, W., 2012, In: Journal of Pharmaceutical Sciences. 101, 3, p. 895-913

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik, 2012, In: Langmuir. 28, 3, p. 1804-1815

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Infrared spectroscopy to characterize protein aggregates

    van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  57. Published

    Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. 2011
  59. Published

    Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)

    van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  60. Published

    Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Fluorescence quenching and ligand binding: A critical discussion of a popular methodology

    van de Weert, Marco & Stella, L., 2011, In: Journal of Molecular Structure: THEOCHEM. 998, 1-3, p. 144-150

    Research output: Contribution to journal › Journal article › Research › peer-review

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