Marco van de Weert
Associate Professor
Drug Delivery and Biophysics of Biopharmaceuticals
Universitetsparken 2, 2100 København Ø, Bygning 13, Building: 13-3-335
- 2019
- Published
The dangers of citing papers you did not read or understand. / van de Weert, Marco; Stella, Lorenzo.
In: Journal of Molecular Structure: THEOCHEM, Vol. 1186, 15.06.2019, p. 102-103.Research output: Contribution to journal › Journal article › Communication
- 2018
- Published
Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation. / von Halling Laier, Christoffer; Gibson, Blake; van de Weert, Marco; Boyd, Ben J; Rades, Thomas; Boisen, Anja; Hook, Sarah; Nielsen, Line Hagner.
In: International Journal of Pharmaceutics, Vol. 550, No. 1-2, 25.10.2018, p. 35-44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles. / Wu, Chengyu; van de Weert, Marco; Baldursdottir, Stefania G; Yang, Mingshi; Mu, Huiling.
In: International Journal of Pharmaceutics, Vol. 550, No. 1-2, 06.09.2018, p. 439-446.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin. / Høgstedt, Ulrich B; Østergaard, Jesper; Weiss, Torsten; Sjögren, Helen; van de Weert, Marco.
In: Journal of Pharmaceutical Sciences, Vol. 107, No. 3, 03.2018, p. 838-847.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme. / Meng-Lund, Helena; Friis, Natascha; van de Weert, Marco; Rantanen, Jukka; Poso, Antti; Grohganz, Holger; Jorgensen, Lene.
In: International Journal of Pharmaceutics, Vol. 523, No. 1, 15.05.2017, p. 238-245.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity. / Lobbens, Eva S B; Vissing, Karina J.; Jorgensen, Lene; van de Weert, Marco; Jäger, Anna K.
In: Journal of Ethnopharmacology, Vol. 200, 22.03.2017, p. 66-73.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions. / Ji, Shuying; Thulstrup, Peter Waaben; Mu, Huiling; Hansen, Steen Honoré; van de Weert, Marco; Rantanen, Jukka; Yang, Mingshi.
In: International Journal of Pharmaceutics, Vol. 534, No. 1-2, 2017, p. 263-271.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions. / Høgstedt, Ulrich B; Schwach, Grégoire; van de Weert, Marco; Østergaard, Jesper.
In: European Journal of Pharmaceutical Sciences, Vol. 93, 25.07.2016, p. 21-28.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS). / Esmail Nazari, Zeinab; van de Weert, Marco; Bou-Assaf, George; Houde, Damian; Weiskopf, Andrew; Rand, Kasper Dyrberg.
In: Journal of Pharmaceutical Sciences, Vol. 105, No. 11, 01.07.2016, p. 3269–3277.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation. / Lobbens, Eva Stephanie; Breydo, Leonid; Pedersen, Thomas Skamris; Vestergaard, Bente; Jäger, Anna K; Jørgensen, Lene; Uversky, Vladimir ; van de Weert, Marco.
In: B B A - Proteins and Proteomics, Vol. 1864, No. 9, 21.06.2016, p. 1160-1169.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin. / Lobbens, Eva Stephanie; Foderà, Vito; Nyberg, Nils; Andersen, Kirsten; Jäger, Anna K; Jørgensen, Lene; van de Weert, Marco.
In: PloS one, Vol. 11, No. 2, e0149148, 16.02.2016, p. 1-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme. / Ji, Shuying; Thulstrup, Peter Waaben; Mu, Huiling; Hansen, Steen Honoré; van de Weert, Marco; Rantanen, Jukka; Yang, Mingshi.
In: International Journal of Pharmaceutics, Vol. 513, No. 1-2, 2016, p. 175-182.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization. / Fonte, Pedro; Andrade, Fernanda; Azevedo, Cláudia; Pinto, João; Seabra, Vítor; van de Weert, Marco; Reis, Salette; Sarmento, Bruno.
In: Pharmaceutical Research, Vol. 33, No. 11, 2016, p. 2777–2793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale biophysical evaluation of protein PEGylation effects : in vitro properties of 61 protein entities. / Vernet, Erik; Popa, Gina; Pozdnyakova, Irina; Rasmussen, Jakob Ewald; Grohganz, Holger; Giehm, Lise; Jensen, Malene Hillerup; Wang, Huabing; Plesner, Bitten; Nielsen, Hanne Mørck; Jensen, Knud Jørgen; Berthelsen, Jens; Sundström, Michael; van de Weert, Marco.
In: Molecular Pharmaceutics, Vol. 13, No. 5, 2016, p. 1587-1598.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin. / Hedegaard, Sofie Cecilie Fogh; Cardenas Gomez, Marite; Barker, Robert; Jørgensen, Lene; van de Weert, Marco.
In: Langmuir, Vol. 32, No. 28, 2016, p. 7241–7249.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra. / Bortolotti, Annalisa; Wong, Yin How; Korsholm, Stine S.; Bahring, Noor Hafizan B; Bobone, Sara; Tayyab, Saad; Van De Weert, Marco; Stella, Lorenzo.
In: RSC Advances, Vol. 6, No. 114, 2016, p. 112870-112876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rhamnogalacturonan-I based microcapsules for targeted drug release. / Svagan, Anna J.; Kusic, Anja; De Gobba, Cristian; Larsen, Flemming Hofmann; Sassene, Philip; Zhou, Qi; Van De Weert, Marco; Mullertz, Anette; Jørgensen, Bodil; Ulvskov, Peter.
In: P L o S One, Vol. 11, No. 12, e0168050, 2016.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization. / Fonte, Pedro; Araújo, Francisca; Seabra, Vítor; Reis, Salette; van de Weert, Marco; Sarmento, Bruno.
In: International Journal of Pharmaceutics, Vol. 496, No. 2, 30.12.2015, p. 850-62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. / Kapp, Sebastian J; Larsson, Iben; Van De Weert, Marco; Ćardenas, Marité; Jorgensen, Lene.
In: Journal of Pharmaceutical Sciences, Vol. 104, No. 10, 10.2015, p. 3587.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces. / Kapp, Sebastian J; Larsson, Iben; van de Weert, Marco; Cardenas Gomez, Marite; Jorgensen, Lene.
In: Journal of Pharmaceutical Sciences, Vol. 104, No. 2, 2015, p. 593-601.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles : A quality-by-design approach. / Rose, Fabrice; Wern, Jeanette Erbo; Ingvarsson, Pall Thor; van de Weert, Marco; Andersen, Peter; Follmann, Frank; Foged, Camilla.
In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 210, 2015, p. 48-57.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein. / Klukkert, Marten; Van De Weert, Marco; Fanø, Mathias; Rades, Thomas; Leopold, Claudia S.
In: Journal of Pharmaceutical Sciences, Vol. 104, No. 12, 2015, p. 4314–4321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preferential interactions and the effect of protein PEGylation. / Holm, Louise Stenstrup; Thulstrup, Peter Waaben; Kasimova, Marina Robertovna; van de Weert, Marco.
In: PLOS ONE, Vol. 10, No. 7, e0133584, 2015.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A reassessment of synchronous fluorescence in the separation of Trp and Tyr contributions in protein emission and in the determination of conformational changes. / Bobone, Sara; van de Weert, Marco; Stella, Lorenzo.
In: Journal of Molecular Structure: THEOCHEM, Vol. 1077, 05.12.2014, p. 68-76.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence spectroscopy and binding : Getting it right. / Stella, Lorenzo; van de Weert, Marco; Burrows, Hugh D.; Fausto, Rui.
In: Journal of Molecular Structure: THEOCHEM, Vol. 1077, 05.12.2014, p. 1-3.Research output: Contribution to journal › Editorial › Research
- Published
Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin. / Weisbjerg, Paul Luigi Gargani; Caspersen, Mikael Bjerg; Cook, Ken; van de Weert, Marco.
In: Journal of Pharmaceutical Sciences, Vol. 104, No. 2, 01.12.2014, p. 548-556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Protein PEGylation on Physical Stability in Liquid Formulation. / Holm, Louise Stenstrup; Mcumber, Aaron; Rasmussen, Jakob Ewald; Obiols-Rabasa, Marc; Thulstrup, Peter W.; Kasimova, Marina R.; Randolph, Theodore W.; van de Weert, Marco.
In: Journal of Pharmaceutical Sciences, Vol. 103, No. 10, 21.08.2014, p. 3043-3054.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex coacervates of hyaluronic acid and lysozyme : Effect on protein structure and physical stability. / Water, Jorrit J.; Schack, Malthe M.; Velazquez-Campoy, Adrian; Maltesen, Morten J.; van de Weert, Marco; Jorgensen, Lene.
In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 88, No. 2, 01.01.2014, p. 325-331.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of monoclonal antibodies at high-concentration : head-to-head comparison of the IgG1 and IgG4 subclass. / Neergaard, Martin S; Nielsen, Anders D; Parshad, Henrik; van de Weert, Marco.
In: Journal of Pharmaceutical Sciences, Vol. 103, No. 1, 01.2014, p. 115-27.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations. / Trnka, Hjalte; Wu, Jian-Xiong; van de Weert, Marco; Grohganz, Holger; Rantanen, Jukka.
In: Journal of Pharmaceutical Sciences, Vol. 102, No. 12, 12.2013, p. 4364-74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The challenges in and importance of analysing protein structure and physical stability in complex formulations. / Jorgensen, L.; Jensen, Minna Grønning; Roest, N.; Pinholt, C.; van de Weert, Marco.
In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 01.07.2013, p. 347-353.Research output: Contribution to journal › Review › Research › peer-review
- Published
Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements. / Neergaard, Martin S; Kalonia, Devendra S; Parshad, Henrik; Nielsen, Anders; Møller, Eva H; van de Weert, Marco; Nielsen, Anders D.
In: European Journal of Pharmaceutical Sciences, Vol. 49, No. 3, 26.04.2013, p. 400-410.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy. / Maltesen, Morten Jonas; van de Weert, Marco; Grohganz, Holger.
In: A A P S PharmSciTech, Vol. 14, No. 2, 21.02.2013, p. 901.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30). / Jensen, Malene Hillerup; Wahlund, Per-Olof; Toft, Katrine Nørgaard; Jacobsen, Jes Kristian; Steensgaard, Dorte Bjerre; van de Weert, Marco; Havelund, Svend; Vestergaard, Bente.
In: Biochemistry, Vol. 52, No. 2, 15.01.2013, p. 282-94.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Therapeutic Peptides and Proteins. / van de Weert, Marco; Arvinte, Tudor.
Pharmaceutical Formulation Development of Peptides and Proteins. ed. / Lars Hovgaard; Sven Frokjaer; Marco van de Weert. 2. ed. Boca Raton : CRC Press, 2013. p. 49-78.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Physical Instability of Peptides and Proteins. / van de Weert, Marco; Randolph, Theodore W.
Pharmaceutical Formulation Development of Peptides and Proteins. ed. / Lars Hovgaard; Sven Frokjaer; Marco van de Weert. 2. ed. Boca Raton : CRC Press, 2013. p. 107-130.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2012
- Published
Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.
In: Journal of Surfactants and Detergents, Vol. 15, 2012, p. 9-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy. / Maltesen, Morten Jonas; van de Weert, Marco; Grohganz, Holger.
In: A A P S PharmSciTech, Vol. 13, No. 3, 2012, p. 747-55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forced degradation of therapeutic proteins. / Hawe, Andrea; Wiggenhorn, Michael; van de Weert, Marco; Garbe, Joerg H. O.; Mahler, Hanns-Christian; Jiskoot, Wim.
In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 895-913.Research output: Contribution to journal › Review › Research › peer-review
- Published
Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.
In: Langmuir, Vol. 28, No. 3, 2012, p. 1804-1815.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared spectroscopy to characterize protein aggregates. / van de Weert, Marco; Jørgensen, Lene.
Analysis of aggregates and particles in protein pharmaceuticals. ed. / Hanns-Christian Mahler; Wim Jiskoot. Hoboken : Wiley, 2012. p. 227-248.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Protease and amylase stability in the presence of chelators used in laundry detergent applications : correlation between chelator properties and enzyme stability in liquid detergents. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.
In: Journal of Surfactants and Detergents, Vol. 15, No. 3, 2012, p. 265-276.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Erratum : Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x). / Van De Weert, Marco.
In: Journal of Fluorescence, Vol. 21, No. 6, 29.08.2011.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Protein adsorption at charged surfaces : the role of electrostatic interactions and interfacial charge regulation. / Hartvig, Rune A.; Van De Weert, Marco; Østergaard, Jesper; Jorgensen, Lene; Jensen, Henrik.
In: Langmuir, Vol. 27, No. 6, 15.03.2011, p. 2634-2643.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence quenching and ligand binding: A critical discussion of a popular methodology. / van de Weert, Marco; Stella, Lorenzo .
In: Journal of Molecular Structure: THEOCHEM, Vol. 998, No. 1-3, 2011, p. 144-150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ionic strength-dependent denaturation ofThermomyces lanuginosus llipase induced by SDS. / Fanø, Mathias; van de Weert, Marco; Møller, Eva Horn; Kruse, Nanna Aaby; Frøkjær, Sven.
In: Archives of Biochemistry and Biophysics, Vol. 506, No. 1, 2011, p. 92-98.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR. / Maltesen, Morten Jonas; Bjerregaard, Simon; Hovgaard, Lars; Havelund, Svend; van de Weert, Marco; Grohganz, Holger.
In: A A P S PharmSciTech, Vol. 12, No. 2, 2011, p. 627-635.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.
In: Langmuir, Vol. 27, 2011, p. 2634-2643.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering. / Jensen, Malene Hillerup; Wahlund, Per-Olof; Jacobsen, Jes K.; Vestergaard, Bente; van de Weert, Marco; Havelund, Svend.
In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 879, No. 28, 2011, p. 2945-2951.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermal and acid denaturation of bovine lens a-crystallin. / Rasmussen, Tue; van de Weert, Marco; Jiskoot, Wim; Kasimova, Marina Robertovna.
In: Proteins - Structure Function and Bioinformatics, Vol. 79, No. 6, 2011, p. 1747-1758.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302800
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309
downloads
Preferential interactions and the effect of protein PEGylation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
146
downloads
On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
138
downloads
Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › Research › peer-review
Published