Marco van de Weert

Marco van de Weert

Associate Professor


  1. 2019
  2. Published

    The dangers of citing papers you did not read or understand. / van de Weert, Marco; Stella, Lorenzo.

    In: Journal of Molecular Structure: THEOCHEM, Vol. 1186, 15.06.2019, p. 102-103.

    Research output: Contribution to journalJournal articleCommunication

  3. 2018
  4. Published

    Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation. / von Halling Laier, Christoffer; Gibson, Blake; van de Weert, Marco; Boyd, Ben J; Rades, Thomas; Boisen, Anja; Hook, Sarah; Nielsen, Line Hagner.

    In: International Journal of Pharmaceutics, Vol. 550, No. 1-2, 25.10.2018, p. 35-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles. / Wu, Chengyu; van de Weert, Marco; Baldursdottir, Stefania G; Yang, Mingshi; Mu, Huiling.

    In: International Journal of Pharmaceutics, Vol. 550, No. 1-2, 06.09.2018, p. 439-446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin. / Høgstedt, Ulrich B; Østergaard, Jesper; Weiss, Torsten; Sjögren, Helen; van de Weert, Marco.

    In: Journal of Pharmaceutical Sciences, Vol. 107, No. 3, 03.2018, p. 838-847.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2017
  8. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme. / Meng-Lund, Helena; Friis, Natascha; van de Weert, Marco; Rantanen, Jukka; Poso, Antti; Grohganz, Holger; Jorgensen, Lene.

    In: International Journal of Pharmaceutics, Vol. 523, No. 1, 15.05.2017, p. 238-245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity. / Lobbens, Eva S B; Vissing, Karina J.; Jorgensen, Lene; van de Weert, Marco; Jäger, Anna K.

    In: Journal of Ethnopharmacology, Vol. 200, 22.03.2017, p. 66-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions. / Ji, Shuying; Thulstrup, Peter Waaben; Mu, Huiling; Hansen, Steen Honoré; van de Weert, Marco; Rantanen, Jukka; Yang, Mingshi.

    In: International Journal of Pharmaceutics, Vol. 534, No. 1-2, 2017, p. 263-271.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. Published

    Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions. / Høgstedt, Ulrich B; Schwach, Grégoire; van de Weert, Marco; Østergaard, Jesper.

    In: European Journal of Pharmaceutical Sciences, Vol. 93, 25.07.2016, p. 21-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS). / Esmail Nazari, Zeinab; van de Weert, Marco; Bou-Assaf, George; Houde, Damian; Weiskopf, Andrew; Rand, Kasper Dyrberg.

    In: Journal of Pharmaceutical Sciences, Vol. 105, No. 11, 01.07.2016, p. 3269–3277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation. / Lobbens, Eva Stephanie; Breydo, Leonid; Pedersen, Thomas Skamris; Vestergaard, Bente; Jäger, Anna K; Jørgensen, Lene; Uversky, Vladimir ; van de Weert, Marco.

    In: B B A - Proteins and Proteomics, Vol. 1864, No. 9, 21.06.2016, p. 1160-1169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin. / Lobbens, Eva Stephanie; Foderà, Vito; Nyberg, Nils; Andersen, Kirsten; Jäger, Anna K; Jørgensen, Lene; van de Weert, Marco.

    In: PloS one, Vol. 11, No. 2, e0149148, 16.02.2016, p. 1-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme. / Ji, Shuying; Thulstrup, Peter Waaben; Mu, Huiling; Hansen, Steen Honoré; van de Weert, Marco; Rantanen, Jukka; Yang, Mingshi.

    In: International Journal of Pharmaceutics, Vol. 513, No. 1-2, 2016, p. 175-182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization. / Fonte, Pedro; Andrade, Fernanda; Azevedo, Cláudia; Pinto, João; Seabra, Vítor; van de Weert, Marco; Reis, Salette; Sarmento, Bruno.

    In: Pharmaceutical Research, Vol. 33, No. 11, 2016, p. 2777–2793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Large-scale biophysical evaluation of protein PEGylation effects : in vitro properties of 61 protein entities. / Vernet, Erik; Popa, Gina; Pozdnyakova, Irina; Rasmussen, Jakob Ewald; Grohganz, Holger; Giehm, Lise; Jensen, Malene Hillerup; Wang, Huabing; Plesner, Bitten; Nielsen, Hanne Mørck; Jensen, Knud Jørgen; Berthelsen, Jens; Sundström, Michael; van de Weert, Marco.

    In: Molecular Pharmaceutics, Vol. 13, No. 5, 2016, p. 1587-1598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin. / Hedegaard, Sofie Cecilie Fogh; Cardenas Gomez, Marite; Barker, Robert; Jørgensen, Lene; van de Weert, Marco.

    In: Langmuir, Vol. 32, No. 28, 2016, p. 7241–7249.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra. / Bortolotti, Annalisa; Wong, Yin How; Korsholm, Stine S.; Bahring, Noor Hafizan B; Bobone, Sara; Tayyab, Saad; Van De Weert, Marco; Stella, Lorenzo.

    In: RSC Advances, Vol. 6, No. 114, 2016, p. 112870-112876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release. / Svagan, Anna J.; Kusic, Anja; De Gobba, Cristian; Larsen, Flemming Hofmann; Sassene, Philip; Zhou, Qi; Van De Weert, Marco; Mullertz, Anette; Jørgensen, Bodil; Ulvskov, Peter.

    In: P L o S One, Vol. 11, No. 12, e0168050, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2015
  23. Published

    Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization. / Fonte, Pedro; Araújo, Francisca; Seabra, Vítor; Reis, Salette; van de Weert, Marco; Sarmento, Bruno.

    In: International Journal of Pharmaceutics, Vol. 496, No. 2, 30.12.2015, p. 850-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. / Kapp, Sebastian J; Larsson, Iben; Van De Weert, Marco; Ćardenas, Marité; Jorgensen, Lene.

    In: Journal of Pharmaceutical Sciences, Vol. 104, No. 10, 10.2015, p. 3587.

    Research output: Contribution to journalComment/debateResearchpeer-review

  25. Published

    Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces. / Kapp, Sebastian J; Larsson, Iben; van de Weert, Marco; Cardenas Gomez, Marite; Jorgensen, Lene.

    In: Journal of Pharmaceutical Sciences, Vol. 104, No. 2, 2015, p. 593-601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles : A quality-by-design approach. / Rose, Fabrice; Wern, Jeanette Erbo; Ingvarsson, Pall Thor; van de Weert, Marco; Andersen, Peter; Follmann, Frank; Foged, Camilla.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 210, 2015, p. 48-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein. / Klukkert, Marten; Van De Weert, Marco; Fanø, Mathias; Rades, Thomas; Leopold, Claudia S.

    In: Journal of Pharmaceutical Sciences, Vol. 104, No. 12, 2015, p. 4314–4321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Preferential interactions and the effect of protein PEGylation. / Holm, Louise Stenstrup; Thulstrup, Peter Waaben; Kasimova, Marina Robertovna; van de Weert, Marco.

    In: PLOS ONE, Vol. 10, No. 7, e0133584, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2014
  30. Published

    A reassessment of synchronous fluorescence in the separation of Trp and Tyr contributions in protein emission and in the determination of conformational changes. / Bobone, Sara; van de Weert, Marco; Stella, Lorenzo.

    In: Journal of Molecular Structure: THEOCHEM, Vol. 1077, 05.12.2014, p. 68-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Fluorescence spectroscopy and binding : Getting it right. / Stella, Lorenzo; van de Weert, Marco; Burrows, Hugh D.; Fausto, Rui.

    In: Journal of Molecular Structure: THEOCHEM, Vol. 1077, 05.12.2014, p. 1-3.

    Research output: Contribution to journalEditorialResearch

  32. Published

    Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin. / Weisbjerg, Paul Luigi Gargani; Caspersen, Mikael Bjerg; Cook, Ken; van de Weert, Marco.

    In: Journal of Pharmaceutical Sciences, Vol. 104, No. 2, 01.12.2014, p. 548-556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation. / Holm, Louise Stenstrup; Mcumber, Aaron; Rasmussen, Jakob Ewald; Obiols-Rabasa, Marc; Thulstrup, Peter W.; Kasimova, Marina R.; Randolph, Theodore W.; van de Weert, Marco.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 10, 21.08.2014, p. 3043-3054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Complex coacervates of hyaluronic acid and lysozyme : Effect on protein structure and physical stability. / Water, Jorrit J.; Schack, Malthe M.; Velazquez-Campoy, Adrian; Maltesen, Morten J.; van de Weert, Marco; Jorgensen, Lene.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 88, No. 2, 01.01.2014, p. 325-331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Stability of monoclonal antibodies at high-concentration : head-to-head comparison of the IgG1 and IgG4 subclass. / Neergaard, Martin S; Nielsen, Anders D; Parshad, Henrik; van de Weert, Marco.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 1, 01.2014, p. 115-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2013
  37. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations. / Trnka, Hjalte; Wu, Jian-Xiong; van de Weert, Marco; Grohganz, Holger; Rantanen, Jukka.

    In: Journal of Pharmaceutical Sciences, Vol. 102, No. 12, 12.2013, p. 4364-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The challenges in and importance of analysing protein structure and physical stability in complex formulations. / Jorgensen, L.; Jensen, Minna Grønning; Roest, N.; Pinholt, C.; van de Weert, Marco.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 01.07.2013, p. 347-353.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements. / Neergaard, Martin S; Kalonia, Devendra S; Parshad, Henrik; Nielsen, Anders; Møller, Eva H; van de Weert, Marco; Nielsen, Anders D.

    In: European Journal of Pharmaceutical Sciences, Vol. 49, No. 3, 26.04.2013, p. 400-410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy. / Maltesen, Morten Jonas; van de Weert, Marco; Grohganz, Holger.

    In: A A P S PharmSciTech, Vol. 14, No. 2, 21.02.2013, p. 901.

    Research output: Contribution to journalComment/debateResearchpeer-review

  41. Published

    Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30). / Jensen, Malene Hillerup; Wahlund, Per-Olof; Toft, Katrine Nørgaard; Jacobsen, Jes Kristian; Steensgaard, Dorte Bjerre; van de Weert, Marco; Havelund, Svend; Vestergaard, Bente.

    In: Biochemistry, Vol. 52, No. 2, 15.01.2013, p. 282-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Characterization of Therapeutic Peptides and Proteins. / van de Weert, Marco; Arvinte, Tudor.

    Pharmaceutical Formulation Development of Peptides and Proteins. ed. / Lars Hovgaard; Sven Frokjaer; Marco van de Weert. 2. ed. Boca Raton : CRC Press, 2013. p. 49-78.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  43. Published

    Physical Instability of Peptides and Proteins. / van de Weert, Marco; Randolph, Theodore W.

    Pharmaceutical Formulation Development of Peptides and Proteins. ed. / Lars Hovgaard; Sven Frokjaer; Marco van de Weert. 2. ed. Boca Raton : CRC Press, 2013. p. 107-130.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  44. 2012
  45. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.

    In: Journal of Surfactants and Detergents, Vol. 15, 2012, p. 9-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy. / Maltesen, Morten Jonas; van de Weert, Marco; Grohganz, Holger.

    In: A A P S PharmSciTech, Vol. 13, No. 3, 2012, p. 747-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Forced degradation of therapeutic proteins. / Hawe, Andrea; Wiggenhorn, Michael; van de Weert, Marco; Garbe, Joerg H. O.; Mahler, Hanns-Christian; Jiskoot, Wim.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 895-913.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.

    In: Langmuir, Vol. 28, No. 3, 2012, p. 1804-1815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Infrared spectroscopy to characterize protein aggregates. / van de Weert, Marco; Jørgensen, Lene.

    Analysis of aggregates and particles in protein pharmaceuticals. ed. / Hanns-Christian Mahler; Wim Jiskoot. Hoboken : Wiley, 2012. p. 227-248.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. Published

    Protease and amylase stability in the presence of chelators used in laundry detergent applications : correlation between chelator properties and enzyme stability in liquid detergents. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.

    In: Journal of Surfactants and Detergents, Vol. 15, No. 3, 2012, p. 265-276.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2011
  52. Published

    Erratum : Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x). / Van De Weert, Marco.

    In: Journal of Fluorescence, Vol. 21, No. 6, 29.08.2011.

    Research output: Contribution to journalComment/debateResearchpeer-review

  53. Published

    Protein adsorption at charged surfaces : the role of electrostatic interactions and interfacial charge regulation. / Hartvig, Rune A.; Van De Weert, Marco; Østergaard, Jesper; Jorgensen, Lene; Jensen, Henrik.

    In: Langmuir, Vol. 27, No. 6, 15.03.2011, p. 2634-2643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Fluorescence quenching and ligand binding: A critical discussion of a popular methodology. / van de Weert, Marco; Stella, Lorenzo .

    In: Journal of Molecular Structure: THEOCHEM, Vol. 998, No. 1-3, 2011, p. 144-150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Ionic strength-dependent denaturation ofThermomyces lanuginosus llipase induced by SDS. / Fanø, Mathias; van de Weert, Marco; Møller, Eva Horn; Kruse, Nanna Aaby; Frøkjær, Sven.

    In: Archives of Biochemistry and Biophysics, Vol. 506, No. 1, 2011, p. 92-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR. / Maltesen, Morten Jonas; Bjerregaard, Simon; Hovgaard, Lars; Havelund, Svend; van de Weert, Marco; Grohganz, Holger.

    In: A A P S PharmSciTech, Vol. 12, No. 2, 2011, p. 627-635.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.

    In: Langmuir, Vol. 27, 2011, p. 2634-2643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering. / Jensen, Malene Hillerup; Wahlund, Per-Olof; Jacobsen, Jes K.; Vestergaard, Bente; van de Weert, Marco; Havelund, Svend.

    In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 879, No. 28, 2011, p. 2945-2951.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Thermal and acid denaturation of bovine lens a-crystallin. / Rasmussen, Tue; van de Weert, Marco; Jiskoot, Wim; Kasimova, Marina Robertovna.

    In: Proteins - Structure Function and Bioinformatics, Vol. 79, No. 6, 2011, p. 1747-1758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. 2010
  61. Published

    Fluorescence quenching to study protein-ligand binding: Common errors. / Van De Weert, Marco.

    In: Journal of Fluorescence, Vol. 20, 2010, p. 625-629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Interfacial complexes between a protein and lipophilic ions at an oil - water interface. / Hartvig, Rune Andersen; Méndez, Manuel A.; van de Weert, Marco; Jørgensen, Lene; Østergaard, Jesper; Girault, Hubert H.; Jensen, Henrik.

    In: Analytical Chemistry, Vol. 82, No. 18, 2010, p. 7699-7705.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis. / Foderà, Vito; van de Weert, Marco; Vestergaard, Bente.

    In: Soft Matter, Vol. 6, No. 18, 2010, p. 4413-4419.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The molecular chaperone a-crystallin as an excipient in an insulin formulation. / Rasmussen, Tue; Tantipolphan, Ruedeeporn; van de Weert, Marco; Jiskoot, Wim.

    In: Pharmaceutical Research, Vol. 27, 2010, p. 1337-1347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2009
  66. Published

    Analysis of insulin allostery in solution and solid state with FTIR. / Maltesen, Morten Jonas; Bjerregaard, Simon; Hovgaard, Lars; Havelund, Svend; Van De Weert, Marco.

    In: Journal of Pharmaceutical Sciences, Vol. 98, No. 9, 2009, p. 3265-3277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Analysis of protein physical stability in lipid based delivery systems : the challenges of lipid drug delivery systems. / Jørgensen, Lene; Martins, Susana; van de Weert, Marco.

    In: Journal of Biomedical Nanotechnology, Vol. 5, No. 4, 2009, p. 401-408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Delivery technologies for biopharmaceuticals : a critical assessment. / Van De Weert, Marco.

    Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. ed. / Lene Jørgensen; Hanne Mørck Nielsen. Chichester : Wiley, 2009. p. 407-411.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  69. Published

    Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis. / Anderot, Maria; Nilsson, Mikael; Végvári, Ákos; Møller, Eva Horn; Van De Weert, Marco; Isaksson, Ronald.

    In: Journal of Chromatography - B, Vol. 877, 2009, p. 892-896.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Infrared spectroscopy of protein pharmaceuticals. / van de Weert, Marco; Jørgensen, Lene.

    Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. ed. / Andreas Barth; Parvez I. Haris. Vol. 2 Amsterdam : IOS Press, 2009. p. 168-177.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  71. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers. / Rasmussen, Tue; Kasimova, Marina Robertovna; Jiskoot, Wim; Van De Weert, Marco.

    In: Biochemistry, Vol. 48, 2009, p. 9313-9320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2008
  73. Published

    Drying methods for protein pharmaceuticals. / Maltesen, Morten Jonas; Van De Weert, Marco.

    In: Drug Discovery Today: Technologies, Vol. 5, No. 2-3, 2008, p. 81-88.

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    Immunogenicity of biopharmaceuticals : methods to reduce immunogenicity and biosimilars. / Van De Weert, Marco; Møller, Eva Horn.

    Immunogenicity of biopharmaceuticals. ed. / Marco van de Weert; Eva Horn Møller. 1. ed. New York : Springer, 2008. p. 97-111.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  75. Published

    Preface. / Van De Weert, Marco; Møller, Eva Horn.

    Immunogenicity of biopharmaceuticals. ed. / Marco van de Weert; Eva Horn Møller. 1. ed. New York : Springer, 2008. p. v-vi.

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearch

  76. Published

    Protein pharmaceuticals. / Van De Weert, Marco; Møller, Eva Horn.

    In: Drug Discovery Today: Technologies, Vol. 5, No. 2-3, 2008, p. 35-36.

    Research output: Contribution to journalEditorialResearch

  77. Published

    Quality by design : Spray drying of insulin intended for inhalation. / Maltesen, Morten Jonas; Bjerregaard, Simon; Hovgaard, Lars; Havelund, Svend; Van De Weert, Marco.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 3, 2008, p. 828-838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Secondary nucleation and accessible surface in insulin amyloid fibril formation. / Foderà, Vito; Librizzi, Fabio; Jensen, Minna Grønning; Van De Weert, Marco; Leone, Maurizio.

    In: Journal of Physical Chemistry B, Vol. 112, No. 12, 2008, p. 3853-3858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach. / Thomsen, Anne Engelbrecht; Jensen, Henrik; Jørgensen, Lene; Van De Weert, Marco; Østergaard, Jesper.

    In: Colloids and Surfaces B: Biointerfaces, Vol. 63, No. 2, 2008, p. 243-248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection. / Foderà, Vito; Jensen, Minna Grønning; Vetri, Valeria; Librizzi, Fabio; Spagnolo, Salvatore; Cornett, Claus; Olsen, Lars; Van De Weert, Marco; Leone, Maurizio.

    In: Journal of Physical Chemistry, Vol. 112, No. 47, 2008, p. 15174-15181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2007
  82. Published

    Bioinformatic and experimental analysis of the secondary structure of amelogenin. / Vilhjalmsson, B.; Rasmussen, A.; Fabi, B.; van de Weert, M.; Hamelryck, T.; Lemoult, S.

    In: European Cells and Materials, Vol. 14, No. SUPPL.2, 01.11.2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils. / Vestergaard, Bente; Jensen, Minna Grønning; Roessle, Manfred; Kastrup, Jette Sandholm Jensen; Van De Weert, Marco; Flink, James M.; Frøkjær, Sven; Gajhede, Michael; Svergun, Dmitri I.

    In: PLoS - Biology, Vol. 5, No. 5, 2007, p. 1089-1097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Binding mode of Thioflavin T in insulin amyloid fibrils. / Jensen, Minna Grønning; Norrman, Mathias; Flink, James M.; van de Weert, Marco; Bukrinsky, Jens T.; Schluckebier, Gerd; Frøkjær, Sven.

    In: Journal of Structural Biology, Vol. 159, No. 3, 2007, p. 483-497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Characterisation and physical stability of PEGylated glucagon. / Stigsnæs, Pernille; Frøkjær, Sven; Bjerregaard, Simon; Van De Weert, Marco; Kingshott, Peter; Møller, Eva Horn.

    In: Internation Journal of Pharmaceutics, Vol. 330, No. 1-2, 2007, p. 89-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan. / Yang, Mingshi; Velaga, S.; Yamamoto, H.; Takeuchi, H.; Kawashima, Y.; Hovgaard, Lars; Van De Weert, Marco; Frøkjær, Sven.

    In: Internation Journal of Pharmaceutics, Vol. 331, No. 2, 2007, p. 176-181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Characterization of a cyclosporine solid dispersion for inhalation. / Zijlstra, Gerrit S.; Rijkeboer, Michiel; van Drooge, Dirk Jan; Sutter, Marc; Jiskoot, Wim; Van De Weert, Marco; Hinrichs, Wouter L. J.; Frijlink, Henderik W.

    In: The AAPS journal, Vol. 9, No. 2, 2007, p. E190-E199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Gennembrud i forståelsen af insulinfibrillering. / Jensen, Minna Grønning; Vestergaard, Bente; Frøkjær, Sven; Gajhede, Michael; Flink, James M.; Van De Weert, Marco; Kastrup, Jette Sandholm Jensen; Svergun, Dmitri I.

    In: Lægemiddelforskning, 2007, p. 10-11.

    Research output: Contribution to journalJournal articleCommunication

  89. Published

    Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles. / Sarmento, B.; Ferreira, D. C.; Jørgensen, Lene; Van De Weert, Marco.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 65, No. 1, 2007, p. 10-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities. / Jensen, Minna Grønning; Olsen, Lars; Van De Weert, Marco; Flink, James M.; Frøkjær, Sven; Jørgensen, Flemming Steen.

    In: Journal of Structural Biology, Vol. 158, No. 3, 2007, p. 358-369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. 2006
  92. Published

    Chemical and thermal stability of insulin : effects of zinc and ligand binding to the insulin zinc-hexamer. / Huus, Kasper; Havelund, Svend; Olsen, Helle B; van de Weert, Marco; Frokjaer, Sven.

    In: Pharmaceutical Research, Vol. 23, No. 11, 11.2006, p. 2611-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Ligand binding and thermostability of different allosteric states of the insulin zinc-hexamer. / Huus, Kasper; Havelund, Svend; Olsen, Helle B; Sigurskjold, Bent W; van de Weert, Marco; Frokjaer, Sven.

    In: Biochemistry, Vol. 45, No. 12, 28.03.2006, p. 4014-4024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Preparing and evaluating delivery systems for proteins. / Jorgensen, L; Moeller, E H; van de Weert, M; Nielsen, H M; Frokjaer, S.

    In: European Journal of Pharmaceutical Sciences, Vol. 29, No. 3-4, 2006, p. 174-82.

    Research output: Contribution to journalReviewResearchpeer-review

  95. 2005
  96. Published

    Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin. / Soenderkaer, S.; Van De Weert, M.; Lindgaard Hansen, L.; Flink, J.; Frokjaer, S.

    In: Journal of Drug Delivery Science and Technology, Vol. 15, No. 6, 01.11.2005, p. 427-434.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Factors of importance for a successful delivery system for proteins. / van de Weert, Marco; Jorgensen, Lene; Horn Moeller, Eva; Frokjaer, Sven.

    In: Expert Opinion on Drug Delivery, Vol. 2, No. 6, 11.2005, p. 1029-37.

    Research output: Contribution to journalReviewResearchpeer-review

  98. Published

    Thermal dissociation and unfolding of insulin. / Huus, Kasper; Havelund, Svend; Olsen, Helle B; van de Weert, Marco; Frokjaer, Sven.

    In: Biochemistry, Vol. 44, No. 33, 23.08.2005, p. 11171-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Complex coacervation with heparin results in decreased lysozyme stability. / van de Weert, Marco; Bendix Andersen, M; Frokjaer, S.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 101, No. 1-3, 03.01.2005, p. 361-2.

    Research output: Contribution to journalConference abstract in journalResearch

  100. Published

    Fourier transform infrared spectroscopy of protein formulations. / van de Weert, Marco; Hering, Joachim A.; Haris, Parvez I.

    Methods for Structural Analysis of Protein Pharmaceuticals. ed. / Wim Jiskoot; Daan Crommelin. Arlington : Springer Science+Business Media, 2005. p. 131-166.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  101. 2004
  102. Published

    Complex coacervation of lysozyme and heparin : complex characterization and protein stability. / van de Weert, Marco; Andersen, Mia Bendix; Frokjaer, Sven.

    In: Pharmaceutical Research, Vol. 21, No. 12, 12.2004, p. 2354-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Probing structural changes of proteins incorporated into water-in-oil emulsions. / Jorgensen, Lene; van de Weert, Marco; Vermehren, Charlotte; Bjerregaard, Simon; Frokjaer, Sven.

    In: Journal of Pharmaceutical Sciences, Vol. 93, No. 7, 07.2004, p. 1847-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Effects of sucrose on rFVIIa aggregation and methionine oxidation. / Soenderkaer, Susanne; Carpenter, John F; van de Weert, Marco; Hansen, Lars Lindgaard; Flink, James; Frokjaer, Sven.

    In: European Journal of Pharmaceutical Sciences, Vol. 21, No. 5, 04.2004, p. 597-606.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Formulation, stability and characterization of protein and peptide drugs. / Frøkjær, Sven; Hovgaard, Lars; van de Weert, Marco.

    Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids. ed. / Ram I. Mahato. Boca Raton : CRC Press, 2004. p. 378-401.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  106. 2002
  107. Stability aspects of salmon calcitonin entrapped in poly(ether-ester) sustained release systems. / van Dijkhuizen-Radersma, R; Nicolas, H M; van de Weert, Marco; Blom, M; de Groot, K; Bezemer, J M.

    In: International Journal of Pharmaceutics, Vol. 248, No. 1-2, 06.11.2002, p. 229-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer. / van de Weert, Marco; van Dijkhuizen-Radersma, Riemke; Bezemer, Jeroen M; Hennink, Wim E; Crommelin, Daan J A.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 54, No. 1, 07.2002, p. 89-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres. / Nijsen, J F; van Het Schip, A D; van Steenbergen, M J; Zielhuis, S W; Kroon-Batenburg, L M J; van de Weert, Marco; van Rijk, P P; Hennink, W E.

    In: Biomaterials, Vol. 23, No. 8, 04.2002, p. 1831-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems : protein release and protein stability issues. / van de Weert, Marco; van Steenbergen, Marinus J; Cleland, Jeffrey L; Heller, Jorge; Hennink, Wim E; Crommelin, Daan J A.

    In: Journal of Pharmaceutical Sciences, Vol. 91, No. 4, 04.2002, p. 1065-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Development of poly(ortho esters) and their application for bovine serum albumin and bupivacaine delivery. / Heller, Jorge; Barr, John; Ng, Steve; Shen, Hui-Rong; Gurny, Robert; Schwach-Abdelaoui, Khadija; Rothen-Weinhold, Alexandra; van de Weert, Marco.

    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 78, No. 1-3, 17.01.2002, p. 133-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. 2001
  113. Fourier transform infrared spectrometric analysis of protein conformation : effect of sampling method and stress factors. / van de Weert, Marco; Haris, P I; Hennink, W E; Crommelin, D J.

    In: Analytical Biochemistry, Vol. 297, No. 2, 15.10.2001, p. 160-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate. / Nijsen, J.F.W.; van Steenbergen, M.J.; Kooijman, H.; Talsma, H.; Kroon-Batenburg, L.M.J.; van de Weert, Marco; van Rijk, P.P.; de Witte, A.; van het Schip, A.D.; Hennink, W.E.

    In: Biomaterials, Vol. 22, 2001, p. 3073-3081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. 2000
  116. Published

    Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques. / Van De Weert, Marco; Van 'T Hof, Ron; Van Der Weerd, Jaap; Heeren, Ron M.A.; Posthuma, George; Hennink, Wim E.; Crommelin, Daan J.A.

    In: Journal of Controlled Release, Vol. 68, No. 1, 31.07.2000, p. 31-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Protein instability in poly(lactic-co-glycolic acid) microparticles. / van de Weert, Marco; Jiskoot, Wim; Hennink, Wim E.

    In: Pharmaceutical Research, Vol. 17, 2000, p. 1159-1167.

    Research output: Contribution to journalReviewResearchpeer-review

  118. Published

    The effect of a water/organic solvent interface on the structural stability of lysozyme. / van de Weert, Marco; Hoechstetter, Julia; Hennink, Wim E.; Crommelin, Daan J.A.

    In: Journal of Controlled Release, 2000, p. 351-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. 1998
  120. Mass spectrometric analysis of oxidized tryptophan. / van de Weert, Marco; Lagerwerf, Fija M.; Haverkamp, Johan; Heerma, Wigger.

    In: Journal of Mass Spectrometry, Vol. 33, 1998, p. 884-891.

    Research output: Contribution to journalJournal articleResearchpeer-review

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