Marco van de Weert

Marco van de Weert

Associate Professor

ORCID: 0000-0002-8530-6441

Publication year:
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1 - 114 out of 114Page size: 500
  1. 2023
  2. Published

    Corrigendum to "Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites" [J. Colloid Interface Sci. 606(Part 2) (2022) 1928-1939]

    Zhou, X., Galparsoro, D. F., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 2023, In: Journal of Colloid and Interface Science. 640, p. 917

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy

    Zhou, X., Sinkjær, Anders Wilgaard, Zhang, Min, Pinholt, H. D., Nielsen, Hanne Mørck, Hatzakis, Nikos, van de Weert, Marco & Foderà, Vito, 2023, In: The Journal of Physical Chemistry Letters. 14, 4, p. 912-919

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2022
  5. Published

    Interchangeability of biosimilars: A study of expert views and visions regarding the science and substitution

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, Minssen, Timo, Hoogland, H., De Bruin, M. L. (., van de Weert, Marco & Almarsdóttir, Anna Birna, 2022, In: PLOS One. 17, 1, p. 1-13 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Ion-Mediated Morphological Diversity in Protein Amyloid Systems

    Chaaban, Hussein Forsberg, Vallooran, J. J., van de Weert, Marco & Foderà, Vito, 2022, In: Journal of Physical Chemistry Letters. 13, 16, p. 3586-3593

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites

    Zhou, X., Fennema Galparsoro, D., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 2022, In: Journal of Colloid and Interface Science. 606, Pt 2, p. 1928-1939

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    Polysorbate 80 Controls Morphology, Structure and Stability of Human Insulin Amyloid-Like Spherulites

    Zhou, X., Galparsoro, D. F., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 10 Aug 2021, bioRxiv, 52 p.

    Research output: Working paper › Preprint

  10. Published

    Evolving biosimilar clinical requirements: A qualitative interview study with industry experts and European national medicines agency regulators

    Druedahl, Louise C., Kälvemark Sporrong, Sofia, van de Weert, Marco, De Bruin, M. L. (., Hoogland, H., Minssen, Timo & Almarsdóttir, Anna Birna, 2021, In: BioDrugs. 35, p. 351-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2020
  12. Published

    A qualitative study of biosimilar manufacturer and regulator perceptions on intellectual property and abbreviated approval pathways

    Druedahl, Louise C., Almarsdóttir, Anna Birna, Kälvemark Sporrong, Sofia, De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kesselheim, A. S. & Sarpatwari, A., 2020, In: Nature Biotechnology. 38, 11, p. 1253-1256 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2019
  15. Published

    MEDICINES AUTHORITY REGULATOR AND INDUSTRY PERCEPTIONS OF BIOSIMILAR INTERCHANGEABILITY

    Druedahl, Louise C., De Bruin, M. L., Hoogland, H., Minssen, Timo, van de Weert, Marco, Kälvemark Sporrong, Sofia & Almarsdóttir, Anna Birna, Dec 2019, p. E45-E46.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  16. Published

    The dangers of citing papers you did not read or understand

    van de Weert, Marco & Stella, L., 15 Jun 2019, In: Journal of Molecular Structure: THEOCHEM. 1186, p. 102-103 2 p.

    Research output: Contribution to journal › Journal article › Communication

  17. Published

    Medicines authority regulators and industry perspectives on the European regulation of biosimilars

    Druedahl, Louise C., De Bruin, M. L. (., van de Weert, Marco, Minssen, Timo, Hoogland, H. & Almarsdóttir, Anna Birna, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  18. 2018
  19. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

    Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

    von Halling Laier, C., Gibson, B., van de Weert, Marco, Boyd, B. J., Rades, Thomas, Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin

    Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2017
  23. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

    Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions

    Ji, S., Thulstrup, Peter Waaben, Mu, Huiling, Hansen, S. H., van de Weert, Marco, Rantanen, Jukka & Yang, Mingshi, 2017, In: International Journal of Pharmaceutics. 534, 1-2, p. 263-271 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2016
  27. Published

    Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions

    Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

    Esmail Nazari, Z., van de Weert, Marco, Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, Kasper Dyrberg, 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

    Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

    Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme

    Ji, S., Thulstrup, Peter Waaben, Mu, Huiling, Hansen, S. H., van de Weert, Marco, Rantanen, Jukka & Yang, Mingshi, 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 175-182 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

    Fonte, P., Andrade, F., Azevedo, C., Pinto, J., Seabra, V., van de Weert, Marco, Reis, S. & Sarmento, B., 2016, In: Pharmaceutical Research. 33, 11, p. 2777–2793

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

    Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra

    Bortolotti, A., Wong, Y. H., Korsholm, S. S., Bahring, N. H. B., Bobone, S., Tayyab, S., van de Weert, Marco & Stella, L., 2016, In: RSC Advances. 6, 114, p. 112870-112876 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release

    Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. 2015
  38. Published

    Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization

    Fonte, P., Araújo, F., Seabra, V., Reis, S., van de Weert, Marco & Sarmento, B., 30 Dec 2015, In: International Journal of Pharmaceutics. 496, 2, p. 850-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

    Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

    Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  42. Published

    Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein

    Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Preferential interactions and the effect of protein PEGylation

    Holm, L. S., Thulstrup, Peter Waaben, Kasimova, M. R. & van de Weert, Marco, 2015, In: PLOS ONE. 10, 7, 18 p., e0133584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2014
  45. Published

    A reassessment of synchronous fluorescence in the separation of Trp and Tyr contributions in protein emission and in the determination of conformational changes

    Bobone, S., van de Weert, Marco & Stella, L., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 68-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Fluorescence spectroscopy and binding: Getting it right

    Stella, L., van de Weert, Marco, Burrows, H. D. & Fausto, R., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 1-3 3 p.

    Research output: Contribution to journal › Editorial › Research

  47. Published

    Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin

    Weisbjerg, P. L. G., Caspersen, M. B., Cook, K. & van de Weert, Marco, 1 Dec 2014, In: Journal of Pharmaceutical Sciences. 104, 2, p. 548-556 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

    Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

    Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2013
  52. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

    Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The challenges in and importance of analysing protein structure and physical stability in complex formulations

    Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements

    Neergaard, M. S., Kalonia, D. S., Parshad, H., Nielsen, A., Møller, E. H., van de Weert, Marco & Nielsen, A. D., 26 Apr 2013, In: European Journal of Pharmaceutical Sciences. 49, 3, p. 400-410 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  56. Published

    Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30)

    Jensen, M. H., Wahlund, P., Toft, K. N., Jacobsen, J. K., Steensgaard, D. B., van de Weert, Marco, Havelund, S. & Vestergaard, Bente, 15 Jan 2013, In: Biochemistry. 52, 2, p. 282-94 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Characterization of Therapeutic Peptides and Proteins

    van de Weert, Marco & Arvinte, T., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 49-78

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  58. Published

    Physical Instability of Peptides and Proteins

    van de Weert, Marco & Randolph, T. W., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 107-130

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  59. 2012
  60. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Correlation between enzyme activity and stability of a protease, an alpha-amylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jorgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Forced degradation of therapeutic proteins

    Hawe, A., Wiggenhorn, M., van de Weert, Marco, Garbe, J. H. O., Mahler, H. & Jiskoot, W., 2012, In: Journal of Pharmaceutical Sciences. 101, 3, p. 895-913

    Research output: Contribution to journal › Review › Research › peer-review

  64. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Infrared spectroscopy to characterize protein aggregates

    van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  66. Published

    Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. 2011
  68. Published

    Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)

    van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  69. Published

    Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Fluorescence quenching and ligand binding: A critical discussion of a popular methodology

    van de Weert, Marco & Stella, L., 2011, In: Journal of Molecular Structure: THEOCHEM. 998, 1-3, p. 144-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Ionic strength-dependent denaturation of Thermomyces lanuginosus lipase induced by SDS

    Fanø, M., van de Weert, Marco, Møller, E. H., Kruse, N. A. & Frøkjær, Sven, 2011, In: Archives of Biochemistry and Biophysics. 506, 1, p. 92-98

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S., van de Weert, Marco & Grohganz, Holger, 2011, In: A A P S PharmSciTech. 12, 2, p. 627-635

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering

    Jensen, M. H., Wahlund, P., Jacobsen, J. K., Vestergaard, Bente, van de Weert, Marco & Havelund, S., 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 28, p. 2945-2951

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Thermal and acid denaturation of bovine lens a-crystallin

    Rasmussen, T., van de Weert, Marco, Jiskoot, W. & Kasimova, M. R., 2011, In: Proteins - Structure Function and Bioinformatics. 79, 6, p. 1747-1758

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. 2010
  77. Published

    Fluorescence quenching to study protein-ligand binding: Common errors

    van de Weert, Marco, 2010, In: Journal of Fluorescence. 20, p. 625-629

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Interfacial complexes between a protein and lipophilic ions at an oil - water interface

    Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis

    Foderà, Vito, van de Weert, Marco & Vestergaard, Bente, 2010, In: Soft Matter. 6, 18, p. 4413-4419

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    The molecular chaperone a-crystallin as an excipient in an insulin formulation

    Rasmussen, T., Tantipolphan, R., van de Weert, Marco & Jiskoot, W., 2010, In: Pharmaceutical Research. 27, p. 1337-1347

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. 2009
  82. Published

    Analysis of insulin allostery in solution and solid state with FTIR

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2009, In: Journal of Pharmaceutical Sciences. 98, 9, p. 3265-3277

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems

    Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Delivery technologies for biopharmaceuticals: a critical assessment

    van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  85. Published

    Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis

    Anderot, M., Nilsson, M., Végvári, Á., Møller, E. H., van de Weert, Marco & Isaksson, R., 2009, In: Journal of Chromatography - B. 877, p. 892-896

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Infrared spectroscopy of protein pharmaceuticals

    van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  87. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers

    Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. 2008
  89. Published

    Drying methods for protein pharmaceuticals

    Maltesen, M. J. & van de Weert, Marco, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 81-88

    Research output: Contribution to journal › Review › Research › peer-review

  90. Published

    Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  91. Published

    Preface

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. v-vi

    Research output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research

  92. Published

    Protein pharmaceuticals

    van de Weert, Marco & Møller, E. H., 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 35-36

    Research output: Contribution to journal › Editorial › Research

  93. Published

    Quality by design: Spray drying of insulin intended for inhalation

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Secondary nucleation and accessible surface in insulin amyloid fibril formation

    Foderà, Vito, Librizzi, F., Jensen, M. G., van de Weert, Marco & Leone, M., 2008, In: Journal of Physical Chemistry B. 112, 12, p. 3853-3858

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection

    Foderà, Vito, Jensen, M. G., Vetri, V., Librizzi, F., Spagnolo, S., Cornett, Claus, Olsen, L., van de Weert, Marco & Leone, M., 2008, In: Journal of Physical Chemistry. 112, 47, p. 15174-15181

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2007
  98. Published

    Bioinformatic and experimental analysis of the secondary structure of amelogenin

    Vilhjalmsson, B., Rasmussen, Anne, Fabi, B., van de Weert, Marco, Hamelryck, Thomas Wim & Lemoult, S., 1 Nov 2007, In: European Cells and Materials. 14, SUPPL.2, 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

    Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Binding mode of Thioflavin T in insulin amyloid fibrils

    Jensen, M. G., Norrman, M., Flink, J. M., van de Weert, Marco, Bukrinsky, J. T., Schluckebier, G. & Frøkjær, Sven, 2007, In: Journal of Structural Biology. 159, 3, p. 483-497

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Characterisation and physical stability of PEGylated glucagon

    Stigsnæs, P., Frøkjær, Sven, Bjerregaard, S., van de Weert, Marco, Kingshott, P. & Møller, E. H., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 89-98

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan

    Yang, Mingshi, Velaga, S., Yamamoto, H., Takeuchi, H., Kawashima, Y., Hovgaard, L., van de Weert, Marco & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 176-181

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Characterization of a cyclosporine solid dispersion for inhalation

    Zijlstra, G. S., Rijkeboer, M., van Drooge, D. J., Sutter, M., Jiskoot, W., van de Weert, Marco, Hinrichs, W. L. J. & Frijlink, H. W., 2007, In: The AAPS journal. 9, 2, p. E190-E199

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Gennembrud i forståelsen af insulinfibrillering

    Jensen, M. G., Vestergaard, Bente, Frøkjær, Sven, Gajhede, Michael, Flink, J. M., van de Weert, Marco, Kastrup, Jette Sandholm Jensen & Svergun, D. I., 2007, In: Lægemiddelforskning. p. 10-11

    Research output: Contribution to journal › Journal article › Communication

  105. Published

    Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

    Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities

    Jensen, M. G., Olsen, L., van de Weert, Marco, Flink, J. M., Frøkjær, Sven & Jørgensen, Flemming Steen, 2007, In: Journal of Structural Biology. 158, 3, p. 358-369

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. 2006
  108. Published

    Chemical and thermal stability of insulin: effects of zinc and ligand binding to the insulin zinc-hexamer

    Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, Nov 2006, In: Pharmaceutical Research. 23, 11, p. 2611-20 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Ligand binding and thermostability of different allosteric states of the insulin zinc-hexamer

    Huus, K., Havelund, S., Olsen, H. B., Sigurskjold, B. W., van de Weert, Marco & Frøkjær, Sven, 28 Mar 2006, In: Biochemistry. 45, 12, p. 4014-4024 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Preparing and evaluating delivery systems for proteins

    Jorgensen, L., Moeller, E. H., van de Weert, Marco, Nielsen, H. M. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 29, 3-4, p. 174-82 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  111. 2005
  112. Published

    Factors of importance for a successful delivery system for proteins

    van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  113. Published

    Thermal dissociation and unfolding of insulin

    Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, 23 Aug 2005, In: Biochemistry. 44, 33, p. 11171-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. Published

    Complex coacervation with heparin results in decreased lysozyme stability

    van de Weert, Marco, Bendix Andersen, M. & Frøkjær, Sven, 3 Jan 2005, In: Journal of controlled release : official journal of the Controlled Release Society. 101, 1-3, p. 361-2 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  115. Published

    Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin

    Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 2005, In: Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. Published

    Fourier transform infrared spectroscopy of protein formulations

    van de Weert, Marco, Hering, J. A. & Haris, P. I., 2005, Methods for Structural Analysis of Protein Pharmaceuticals. Jiskoot, W. & Crommelin, D. (eds.). Arlington: Springer Science+Business Media, p. 131-166

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  117. 2004
  118. Published

    Complex coacervation of lysozyme and heparin: complex characterization and protein stability

    van de Weert, Marco, Andersen, M. B. & Frøkjær, Sven, Dec 2004, In: Pharmaceutical Research. 21, 12, p. 2354-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    Probing structural changes of proteins incorporated into water-in-oil emulsions

    Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  120. Published

    Effects of sucrose on rFVIIa aggregation and methionine oxidation

    Soenderkaer, S., Carpenter, J. F., van de Weert, Marco, Hansen, L. L., Flink, J. & Frøkjær, Sven, Apr 2004, In: European Journal of Pharmaceutical Sciences. 21, 5, p. 597-606 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  121. Published

    Formulation, stability and characterization of protein and peptide drugs

    Frøkjær, Sven, Hovgaard, L. & van de Weert, Marco, 2004, Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids. Mahato, R. I. (ed.). Boca Raton: CRC Press, p. 378-401

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  122. 2002

  123. Stability aspects of salmon calcitonin entrapped in poly(ether-ester) sustained release systems

    van Dijkhuizen-Radersma, R., Nicolas, H. M., van de Weert, Marco, Blom, M., de Groot, K. & Bezemer, J. M., 6 Nov 2002, In: International Journal of Pharmaceutics. 248, 1-2, p. 229-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  124. Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer

    van de Weert, Marco, van Dijkhuizen-Radersma, R., Bezemer, J. M., Hennink, W. E. & Crommelin, D. J. A., Jul 2002, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 54, 1, p. 89-93 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  125. Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres

    Nijsen, J. F., van Het Schip, A. D., van Steenbergen, M. J., Zielhuis, S. W., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P. & Hennink, W. E., Apr 2002, In: Biomaterials. 23, 8, p. 1831-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  126. Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues

    van de Weert, Marco, van Steenbergen, M. J., Cleland, J. L., Heller, J., Hennink, W. E. & Crommelin, D. J. A., Apr 2002, In: Journal of Pharmaceutical Sciences. 91, 4, p. 1065-74 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  127. Development of poly(ortho esters) and their application for bovine serum albumin and bupivacaine delivery

    Heller, J., Barr, J., Ng, S., Shen, H., Gurny, R., Schwach-Abdelaoui, K., Rothen-Weinhold, A. & van de Weert, Marco, 17 Jan 2002, In: Journal of controlled release : official journal of the Controlled Release Society. 78, 1-3, p. 133-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  128. 2001

  129. Fourier transform infrared spectrometric analysis of protein conformation: effect of sampling method and stress factors

    van de Weert, Marco, Haris, P. I., Hennink, W. E. & Crommelin, D. J., 15 Oct 2001, In: Analytical Biochemistry. 297, 2, p. 160-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  130. Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate

    Nijsen, J. F. W., van Steenbergen, M. J., Kooijman, H., Talsma, H., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P., de Witte, A., van het Schip, A. D. & Hennink, W. E., 2001, In: Biomaterials. 22, p. 3073-3081

    Research output: Contribution to journal › Journal article › Research › peer-review

  131. 2000
  132. Published

    Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques

    van de Weert, Marco, Van 'T Hof, R., Van Der Weerd, J., Heeren, R. M. A., Posthuma, G., Hennink, W. E. & Crommelin, D. J. A., 31 Jul 2000, In: Journal of Controlled Release. 68, 1, p. 31-40 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  133. Protein instability in poly(lactic-co-glycolic acid) microparticles

    van de Weert, Marco, Jiskoot, W. & Hennink, W. E., 2000, In: Pharmaceutical Research. 17, p. 1159-1167

    Research output: Contribution to journal › Review › Research › peer-review

  134. Published

    The effect of a water/organic solvent interface on the structural stability of lysozyme

    van de Weert, Marco, Hoechstetter, J., Hennink, W. E. & Crommelin, D. J. A., 2000, In: Journal of Controlled Release. p. 351-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  135. 1998

  136. Mass spectrometric analysis of oxidized tryptophan

    van de Weert, Marco, Lagerwerf, F. M., Haverkamp, J. & Heerma, W., 1998, In: Journal of Mass Spectrometry. 33, p. 884-891

    Research output: Contribution to journal › Journal article › Research › peer-review

  137. Stability of pharmaceutical proteins in particulate carriers

    van de Weert, Marco, van 't Hof, R., Hennink, W. E. & Crommelin, D. J. A., 1998, Alfred Benzon Symposium proceedings. Frøkjær, S., Christrup, L. & Krogsgaard-Larsen, P. (eds.). Copenhagen: Munksgaard , Vol. 43. p. 359-375

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  138. 1996

  139. Identification of oxidized methionine in peptides

    Lagerwerf, F. M., van de Weert, Marco, Heerma, W. & Haverkamp, J., 1996, In: Rapid Communications in Mass Spectrometry. 10, p. 1905-1910

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 1302800