Marco van de Weert

Marco van de Weert

Associate Professor


  1. Published

    Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In : A A P S PharmSciTech. 14, 2, p. 901 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. Published

    Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S., van de Weert, Marco & Grohganz, Holger, 2011, In : A A P S PharmSciTech. 12, 2, p. 627-635

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In : International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

    Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In : Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements

    Neergaard, M. S., Kalonia, D. S., Parshad, H., Nielsen, A., Møller, E. H., van de Weert, Marco & Nielsen, A. D., 26 Apr 2013, In : European Journal of Pharmaceutical Sciences. 49, 3, p. 400-410 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres

    Nijsen, J. F., van Het Schip, A. D., van Steenbergen, M. J., Zielhuis, S. W., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P. & Hennink, W. E., Apr 2002, In : Biomaterials. 23, 8, p. 1831-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate

    Nijsen, J. F. W., van Steenbergen, M. J., Kooijman, H., Talsma, H., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P., de Witte, A., van het Schip, A. D. & Hennink, W. E., 2001, In : Biomaterials. 22, p. 3073-3081

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers

    Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In : Biochemistry. 48, p. 9313-9320

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The molecular chaperone a-crystallin as an excipient in an insulin formulation

    Rasmussen, T., Tantipolphan, R., van de Weert, Marco & Jiskoot, W., 2010, In : Pharmaceutical Research. 27, p. 1337-1347

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Thermal and acid denaturation of bovine lens a-crystallin

    Rasmussen, T., van de Weert, Marco, Jiskoot, W. & Kasimova, M. R., 2011, In : Proteins - Structure Function and Bioinformatics. 79, 6, p. 1747-1758

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In : Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

    Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In : European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin

    Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 2005, In : Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of sucrose on rFVIIa aggregation and methionine oxidation

    Soenderkaer, S., Carpenter, J. F., van de Weert, Marco, Hansen, L. L., Flink, J. & Frøkjær, Sven, Apr 2004, In : European Journal of Pharmaceutical Sciences. 21, 5, p. 597-606 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Fluorescence spectroscopy and binding: Getting it right

    Stella, L., van de Weert, Marco, Burrows, H. D. & Fausto, R., 5 Dec 2014, In : Journal of Molecular Structure: THEOCHEM. 1077, p. 1-3 3 p.

    Research output: Contribution to journalEditorialResearch

  16. Published

    Characterisation and physical stability of PEGylated glucagon

    Stigsnæs, P., Frøkjær, Sven, Bjerregaard, S., van de Weert, Marco, Kingshott, P. & Møller, E. H., 2007, In : Internation Journal of Pharmaceutics. 330, 1-2, p. 89-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Rhamnogalacturonan-I based microcapsules for targeted drug release

    Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In : P L o S One. 11, 12, 13 p., e0168050.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, Henrik, Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In : Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

    Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In : Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)

    van de Weert, Marco, 29 Aug 2011, In : Journal of Fluorescence. 21, 6, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Published

    Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques

    van de Weert, Marco, Van 'T Hof, R., Van Der Weerd, J., Heeren, R. M. A., Posthuma, G., Hennink, W. E. & Crommelin, D. J. A., 31 Jul 2000, In : Journal of Controlled Release. 68, 1, p. 31-40 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Preface

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. v-vi

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearch

  23. Published

    Delivery technologies for biopharmaceuticals: a critical assessment

    van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  24. Published

    Fluorescence quenching to study protein-ligand binding: Common errors

    van de Weert, Marco, 2010, In : Journal of Fluorescence. 20, p. 625-629

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Protein pharmaceuticals

    van de Weert, Marco & Møller, E. H., 2008, In : Drug Discovery Today: Technologies. 5, 2-3, p. 35-36

    Research output: Contribution to journalEditorialResearch

  26. Published

    Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  27. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In : Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

    Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In : PLoS - Biology. 5, 5, p. 1089-1097

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Bioinformatic and experimental analysis of the secondary structure of amelogenin

    Vilhjalmsson, B., Rasmussen, Anne, Fabi, B., van de Weert, Marco, Hamelryck, Thomas Wim & Lemoult, S., 1 Nov 2007, In : European Cells and Materials. 14, SUPPL.2, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

    Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In : European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin

    Weisbjerg, P. L. G., Caspersen, M. B., Cook, K. & van de Weert, Marco, 1 Dec 2014, In : Journal of Pharmaceutical Sciences. 104, 2, p. 548-556 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

    Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 6 Sep 2018, In : International Journal of Pharmaceutics. 550, 1-2, p. 439-446

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan

    Yang, Mingshi, Velaga, S., Yamamoto, H., Takeuchi, H., Kawashima, Y., Hovgaard, L., van de Weert, Marco & Frøkjær, Sven, 2007, In : Internation Journal of Pharmaceutics. 331, 2, p. 176-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Characterization of a cyclosporine solid dispersion for inhalation

    Zijlstra, G. S., Rijkeboer, M., van Drooge, D. J., Sutter, M., Jiskoot, W., van de Weert, Marco, Hinrichs, W. L. J. & Frijlink, H. W., 2007, In : The AAPS journal. 9, 2, p. E190-E199

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Stability aspects of salmon calcitonin entrapped in poly(ether-ester) sustained release systems

    van Dijkhuizen-Radersma, R., Nicolas, H. M., van de Weert, Marco, Blom, M., de Groot, K. & Bezemer, J. M., 6 Nov 2002, In : International Journal of Pharmaceutics. 248, 1-2, p. 229-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Fourier transform infrared spectroscopy of protein formulations

    van de Weert, Marco, Hering, J. A. & Haris, P. I., 2005, Methods for Structural Analysis of Protein Pharmaceuticals. Jiskoot, W. & Crommelin, D. (eds.). Arlington: Springer Science+Business Media, p. 131-166

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  37. Stability of pharmaceutical proteins in particulate carriers

    van de Weert, Marco, van 't Hof, R., Hennink, W. E. & Crommelin, D. J. A., 1998, Alfred Benzon Symposium proceedings. Frøkjær, S., Christrup, L. & Krogsgaard-Larsen, P. (eds.). Copenhagen: Munksgaard , Vol. 43. p. 359-375

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  38. Published

    Factors of importance for a successful delivery system for proteins

    van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In : Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Fluorescence quenching and ligand binding: A critical discussion of a popular methodology

    van de Weert, Marco & Stella, L., 2011, In : Journal of Molecular Structure: THEOCHEM. 998, 1-3, p. 144-150

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The effect of a water/organic solvent interface on the structural stability of lysozyme

    van de Weert, Marco, Hoechstetter, J., Hennink, W. E. & Crommelin, D. J. A., 2000, In : Journal of Controlled Release. p. 351-359

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The dangers of citing papers you did not read or understand

    van de Weert, Marco & Stella, L., 15 Jun 2019, In : Journal of Molecular Structure: THEOCHEM. 1186, p. 102-103 2 p.

    Research output: Contribution to journalJournal articleCommunication

  42. Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer

    van de Weert, Marco, van Dijkhuizen-Radersma, R., Bezemer, J. M., Hennink, W. E. & Crommelin, D. J. A., Jul 2002, In : European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 54, 1, p. 89-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Protein instability in poly(lactic-co-glycolic acid) microparticles

    van de Weert, Marco, Jiskoot, W. & Hennink, W. E., 2000, In : Pharmaceutical Research. 17, p. 1159-1167

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Complex coacervation with heparin results in decreased lysozyme stability

    van de Weert, Marco, Bendix Andersen, M. & Frøkjær, Sven, 3 Jan 2005, In : Journal of controlled release : official journal of the Controlled Release Society. 101, 1-3, p. 361-2 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  45. Published

    Infrared spectroscopy to characterize protein aggregates

    van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  46. Mass spectrometric analysis of oxidized tryptophan

    van de Weert, Marco, Lagerwerf, F. M., Haverkamp, J. & Heerma, W., 1998, In : Journal of Mass Spectrometry. 33, p. 884-891

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues

    van de Weert, Marco, van Steenbergen, M. J., Cleland, J. L., Heller, J., Hennink, W. E. & Crommelin, D. J. A., Apr 2002, In : Journal of Pharmaceutical Sciences. 91, 4, p. 1065-74 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Fourier transform infrared spectrometric analysis of protein conformation: effect of sampling method and stress factors

    van de Weert, Marco, Haris, P. I., Hennink, W. E. & Crommelin, D. J., 15 Oct 2001, In : Analytical Biochemistry. 297, 2, p. 160-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Characterization of Therapeutic Peptides and Proteins

    van de Weert, Marco & Arvinte, T., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 49-78

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  50. Published

    Physical Instability of Peptides and Proteins

    van de Weert, Marco & Randolph, T. W., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 107-130

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

ID: 1302800