Jukka Rantanen

Jukka Rantanen

Professor


  1. Published

    In situ measurement of solvent-mediated phase transformations during dissolution testing

    Aaltonen, J., Heinänen, P., Peltonen, L., Kortejärvi, H., Tanninen, V. P., Christiansen, L., Hirvonen, J., Yliruusi, J. & Rantanen, Jukka, Dec 2006, In : Journal of Pharmaceutical Sciences. 95, 12, p. 2730-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Solid form screening: A review

    Aaltonen, J., Allesø, M., Mirza, S., Koradia, V. S., Gordon, K. C. & Rantanen, Jukka, 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 23-37

    Research output: Contribution to journalReviewResearch

  3. Published

    Hyphenated spectroscopy as a polymorph screening tool

    Aaltonen, J., Strachan, C. J., Pöllänen, K., Yliruusi, J. & Rantanen, Jukka, 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 44, 2, p. 477-483

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    In-line monitoring of solid-state transitions during fluidisation

    Aaltonen, J., Kogermann, K., Strachan, C. J. & Rantanen, Jukka, 2007, In : Chemical Engineering Science. 62, 1-2, p. 408-415

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The flow properties and presence of crystals in drug-polymer mixtures: Rheological investigation combined with light microscopy

    Aho, J., Van Renterghem, J., Arnfast, L., De Beer, T. & Rantanen, Jukka, 7 Aug 2017, In : International Journal of Pharmaceutics. 528, 1-2, p. 383-394 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Roadmap to 3D printed oral pharmaceutical dosage forms: Feedstock filament properties and characterization for fused deposition modeling

    Aho, J., Bøtker, Johan Peter, Genina, Natalja, Edinger, M., Arnfast, L. & Rantanen, Jukka, 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 26–35

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Oscillatory Shear Rheology in Examining the Drug-Polymer Interactions Relevant in Hot Melt Extrusion

    Aho, J., Edinger, M., Bøtker, Johan Peter, Baldursdottir, S. & Rantanen, Jukka, Jan 2016, In : Journal of Pharmaceutical Sciences. 105, 1, p. 160-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The effect of HPMC and MC as pore formers on the rheology of the implant microenvironment and the drug release in vitro

    Aho, J., Halme, A., Bøtker, Johan Peter, Water, J. J., Bohr, A., Sandler, N., Rantanen, Jukka & Baldursdottir, S., 1 Dec 2017, In : Carbohydrate Polymers. 177, p. 433-442 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Rheology as a tool for evaluation of melt processability of innovative dosage forms

    Aho, J. M., Bøtker, Johan Peter, Baldursdottir, S. & Rantanen, Jukka, 30 Oct 2015, In : International Journal of Pharmaceutics. 494, 2, p. 623–642 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Solubility of small-molecule drugs into polymer excipients in hot melt extruded dosage forms

    Aho, J. M., Bøtker, Johan Peter, Baldursdottir, S. G. & Rantanen, Jukka, 2014, In : Annual transactions of the Nordic Rheology Society. 22, p. 55-59

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Effects of excipients on hydrate formation in wet masses containing theophylline

    Airaksinen, S., Luukkonen, P., Jørgensen, A., Karjalainen, M., Rantanen, Jukka & Yliruusi, J., Mar 2003, In : Journal of Pharmaceutical Sciences. 92, 3, p. 516-28 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Comparison of the effects of two drying methods on polymorphism of theophylline

    Airaksinen, S., Karjalainen, M., Räsänen, E., Rantanen, Jukka & Yliruusi, J., 19 May 2004, In : International Journal of Pharmaceutics. 276, 1-2, p. 129-41 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Role of water in the physical stability of solid dosage formulations

    Airaksinen, S., Karjalainen, M., Shevchenko, A., Westermarck, S., Leppänen, E., Rantanen, Jukka & Yliruusi, J., Oct 2005, In : Journal of Pharmaceutical Sciences. 94, 10, p. 2147-65 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The Use of 3D Printed Molds to Cast Tablets with a Designed Disintegration Profile

    Ajmal, A., Meskarzadeh, A., Genina, Natalja, Hirschberg, C., Bøtker, Johan Peter & Rantanen, Jukka, 26 Feb 2019, In : AAPS PharmSciTech. 20, 3, 10 p., 127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)

    Aksu, B., De Beer, T., Folestad, S., Ketolainen, J., Lindén, H., Lopes, J. A., de Matas, M., Oostra, W., Rantanen, Jukka & Weimer, M., 29 Sep 2012, In : European Journal of Pharmaceutical Sciences. 47, 2, p. 402-405 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Unveiling multiple solid-state transitions in pharmaceutical solid dosage forms using multi-series hyperspectral imaging and different curve resolution approaches

    Alexandrino, G. L., Amigo Rubio, J. M., Khorasani, M. R., Rantanen, Jukka, Friderichsen, A. V. & Poppi, R. J., 2017, In : Chemometrics and Intelligent Laboratory Systems. 161, p. 136-146 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Monitoring of multiple solid-state transformations at tablet surfaces using multi-series near-infrared hyperspectral imaging and multivariate curve resolution

    Alexandrino, G. L., Khorasani, M. R., Amigo Rubio, J. M., Rantanen, Jukka & Poppi, R. J., 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 224-230 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen-cimetidine mixtures prepared by mechanical activation

    Allesø, M., Chieng, N., Rehder, S., Rantanen, Jukka, Rades, T. & Aaltonen, J., 2009, In : Journal of Controlled Release. 136, p. 45-53

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Solvent subset selection for polymorph screening

    Allesø, M., Rantanen, Jukka, Aaltonen, J., Cornett, Claus & van den Berg, F. W. J., 2008, In : Journal of Chemometrics. 22, 11-12, p. 621-631

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Solvent diversity in polymorph screening

    Allesø, M., van der Berg, Franciscus Winfried J, Cornett, Claus, Jørgensen, Flemming Steen, Halling-Sørensen, B., Lopez de Diego, H., Hovgaard, L., Aaltonen, J. & Rantanen, Jukka, 2008, In : Journal of Pharmaceutical Sciences. 97, 6, p. 2145-2159

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Near-infrared spectroscopy for cocrystal screening: a comparative study with Raman spectroscopy

    Allesø, M., Velaga, S., Alhalaweh, A., Cornett, Claus, Rasmussen, Morten Arendt, van der Berg, Franciscus Winfried J, de Diego, H. L. & Rantanen, Jukka, 2008, In : Analytical Chemistry. 80, 20, p. 7755-7764 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Towards effective solid form screening

    Allesø, M., Tian, F., Cornett, Claus & Rantanen, Jukka, 2010, In : Journal of Pharmaceutical Sciences. 99, 9, p. 3711-3718

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Moving towards continuous manufacturing with NIRS and NIR-CI systems

    Amigo Rubio, J. M., Khorasani, M. R., Rantanen, Jukka & Bertelsen, P., 2014, In : European Pharmaceutical Review. 19, 4, p. 51-55 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations

    Arnfast, L., Kamruzzaman, M., Löbmann, Korbinian, Aho, J., Baldursdottir, S., Rades, Thomas & Rantanen, Jukka, Dec 2017, In : Pharmaceutical Research. 34, 12, p. 2689-2697

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

    Arnfast, L., van Renterghem, J., Aho, J., Bøtker, Johan Peter, Raijada, D., Baldursdóttir, S., De Beer, T. & Rantanen, Jukka, 2020, In : Pharmaceutics. 12, 2, 14 p., 116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Quality by design approach in the optimization of the spray-drying process

    Baldinger, A., Clerdent, L., Rantanen, Jukka, Yang, Mingshi & Grohganz, Holger, 2012, In : Pharmaceutical Development and Technology. 17, 4, p. 389-397

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Controlling solid state properties of pharmaceuticals with polymer selection

    Baldursdóttir, S. G., Tian, F. & Rantanen, Jukka, 2008, In : Nordic Rheology Society Annual Transactions.

    Research output: Contribution to journalConference articleResearch

  28. Published

    The influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG)

    Baldursdóttir, S. G., Tian, F., Santacruz, B. G., Jørgensen, A. C. & Rantanen, Jukka, 2012, In : Pharmaceutical Development and Technology. 17, 2, p. 195-203

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    In silico product design of pharmaceuticals

    Bøtker, Johan Peter, Raijada, D., Aho, J., Khorasani, M., Søgaard, S. V., Arnfast, L., Bohr, A., Edinger, M., Water, J. & Rantanen, Jukka, 2016, In : Asian Journal of Pharmaceutical Sciences. 11, 4, p. 492–499 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Modifying release characteristics from 3D printed drug-eluting products

    Bøtker, Johan Peter, Water, J., Aho, J., Arnfast, L., Bohr, A. & Rantanen, Jukka, 2016, In : European Journal of Pharmaceutical Sciences. 90, p. 47-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

    Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In : Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routes

    Bøtker, Johan Peter, Koradia, V., Rades, T., Rantanen, Jukka & Savolainen, M., 28 Aug 2012, In : Pharmaceutics. 4, 1, p. 93-103 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach

    Bohr, A., Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 2014, In : Current Pharmaceutical Design. 20, 3, p. 325-48 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    High-Throughput Fabrication of Nanocomplexes Using 3D-Printed Micromixers

    Bohr, A., Bøtker, Johan Peter, Wang, Yingya, Jensen, Henrik, Rantanen, Jukka & Beck-Broichsitter, M., 2017, In : Journal of Pharmaceutical Sciences. 106, 3, p. 835-842 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach

    Bohr, A. J., Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 2013, In : Current Pharmaceutical Design. 20, 3, p. 325-348

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system

    Bond, A., Cornett, Claus, Larsen, F. H., Qu, H., Raijada, D. K. & Rantanen, Jukka, 2014, In : IUCrJ. 1, 5, p. 328-337 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Interpreting the disordered crystal structure of Sodium Naproxen Tetrahydrate

    Bond, A., Cornett, Claus, Larsen, F. H., Qu, H., Raijada, D. K. & Rantanen, Jukka, 2013, In : Crystal Growth & Design. 13, 8, p. 3665−3671 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design

    Borro, B. C., Bohr, A., Bucciarelli, S., Bøtker, Johan Peter, Foged, Camilla, Rantanen, Jukka & Malmsten, Martin, 7 Mar 2019, In : Journal of Colloid and Interface Science. 538, p. 559-568 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in Type 1 diabetes mellitus

    Brock, C., Jessen, N., Brock, Birgitte, Jakobsen, P. E., Hansen, T. K., Rantanen, Jukka, Riahi, S., Dimitrova, Y. K., Dons-Jensen, A., Aziz, Q., Drewes, A. M. & Farmer, A. D., Oct 2017, In : Diabetic Medicine. 34, 10, p. 1428-1434 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Hyperspectral imaging as a part of pharmaceutical product design

    Bøtker, Johan Peter, Wu, J. X. & Rantanen, Jukka, 2020, Data Handling in Science and Technology. Elsevier Ltd, p. 567-581 15 p. (Data Handling in Science and Technology, Vol. 32).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  41. Published

    Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions

    Bøtker, Johan Peter, Karmwar, P., Strachan, C. J., Cornett, Claus, Tian, F., Zujovic, Z., Rantanen, Jukka & Rades, Thomas, 2011, In : International Journal of Pharmaceutics. 417, 1-2, p. 112-119 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

    Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structural elucidationof rapid solution-mediatedPhase transitions in pharmaceutical solids using in situ synchrotron SAXS/WAXS

    Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka, Hawley, A. & Boyd, B. J., 1 Aug 2012, In : Molecular Pharmaceutics. 9, 9, p. 2787-2791

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A new approach to dissolution testing by UV imaging and finite element simulations

    Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, Henrik, 2013, In : Pharmaceutical Research. 30, 5, p. 1328-1337

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Physical stability and moisture sorption of aqueous chitosan-amylose starch films plasticized with polyols

    Cervera, M. F., Karjalainen, M., Airaksinen, S., Rantanen, Jukka, Krogars, K., Heinämäki, J., Colarte, A. I. & Yliruusi, J., Jul 2004, In : European Journal of Pharmaceutics and Biopharmaceutics. 58, 1, p. 69-76 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis

    Chieng, N., Trnka, H., Bøtker, Johan Peter, Pikal, M., Rantanen, Jukka & Grohganz, Holger, 18 Jul 2013, In : International Journal of Pharmaceutics. 454, 1, p. 167-173 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01

    Christensen, D., Allesø, M., Rosenkrands, I., Rantanen, Jukka, Foged, Camilla, Agger, E. M., Andersen, P. & Nielsen, Hanne Mørck, 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 914-920

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Disproportionation of the calcium salt of atorvastatin in the presence of acidic excipients

    Christensen, N. P. A., Rantanen, Jukka, Cornett, Claus & Taylor, L. S., 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 2, p. 410-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Role of excipients on solid-state properties of piroxicam during processing

    Christensen, N. P. A., Cornett, Claus & Rantanen, Jukka, 2012, In : Journal of Pharmaceutical Sciences. 101, 3, p. 1202-1211

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Rapid insight into heating-induced phase transformations in the solid state of the calcium salt of atorvastatin using multivariate data analysis

    Christensen, N. P. A., Van Eerdenbrugh, B., Kwok, K., Taylor, L. S., Bond, A., Rades, Thomas, Rantanen, Jukka & Cornett, Claus, Mar 2013, In : Pharmaceutical Research. 30, 3, p. 826-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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