Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
- 2023
- Published
Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization
Bock, Frederik, Hu, A., Cicale, V., Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel
Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of diclofenac release and dynamic structural behavior of non-lamellar liquid crystal formulations during in situ formation by UV–Vis imaging and SAXS
Mertz, Nina, Bock, Frederik, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 2022, In: International Journal of Pharmaceutics. 623, 121880.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance
Bock, Frederik, Bøtker, Johan Peter, Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2022, In: International Journal of Molecular Sciences. 23, 7, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: International Journal of Pharmaceutics. 609, 12 p., 121183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of drug compact topography as relates to intrinsic dissolution rates determined by dissolution imaging
Brown, B., Fazili, Z., Ward, A., Walton, K., Blunt, L., Østergaard, Jesper & Asare-Addo, K., 2021, In: Journal of Drug Delivery Science and Technology. 61, 10 p., 102143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of selenium nanoparticles in human plasma by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry
Gronbaek-Thorsen, F., Hansen, R. H., Østergaard, Jesper, Gammelgaard, Bente & Moller, L. H., 2021, In: Analytical and Bioanalytical Chemistry. 413, 8, p. 2247-2255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of UV dissolution imaging to pharmaceutical systems
Brown, B., Ward, A., Fazili, Z., Østergaard, Jesper & Asare-Addo, K., 2021, In: Advanced Drug Delivery Reviews. 177, 26 p., 113949.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparison of external calibration and isotope dilution LC-ICP-MS/MS for quantitation of oxytocin and its selenium analogue in human plasma
Grønbæk-Thorsen, F., Jensen, C., Østergaard, Jesper, Møller, L. H. & Gammelgaard, Bente, 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 6479–6488Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films
He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species
Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media
Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution
Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
In-Solution IgG Titer Determination in Fermentation Broth Using Affibodies and Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 28 Apr 2020, In: ACS Omega. 5, 18, p. 10519-10524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution
Etherson, K., Dunn, C., Matthews, W., Pamelund, H., Barragat, C., Sanderson, N., Izumi, T., Mathews, C. D. C., Halbert, G., Wilson, C., McAllister, M., Mann, J., Østergaard, Jesper, Butler, J. & Khadra, I., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 150, p. 24-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, Jesper & Fotaki, N., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation
Storgaard, Ida Klitzing, Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 2020, In: Journal of Pharmaceutical Sciences. 109, 4, p. P1529-1536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Initial Leuprolide Acetate Release from Poly(D,L-lactide-co-glycolide) in Situ Forming Implants as Studied by Ultraviolet-Visible Imaging
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2020, In: Molecular Pharmaceutics. 17, 12, p. 4522-4532 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro
He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards in vitro in vivo correlation for modified release subcutaneously administered insulins
Bock, Frederik, Lin, E., Larsen, C., Jensen, H., Huus, K., Larsen, Susan Weng & Østergaard, Jesper, 2020, In: European Journal of Pharmaceutical Sciences. 145, 10 p., 105239.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables
Mertz, Nina, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 20 Jul 2019, In: International Journal of Pharmaceutics. 566, p. 445-453Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach
Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2019, Clinical Applications of Capillary Electrophoresis. Springer, Vol. 1972. p. 109-123 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Monitoring of antimicrobial drug chloramphenicol release from electrospun nano-and microfiber mats using UV imaging and bacterial bioreporters
Preem, L., Bock, Frederik, Hinnu, M., Putrinš, M., Sagor, K., Tenson, T., Meos, A., Østergaard, Jesper & Kogermann, K., 2019, In: Pharmaceutics. 11, 9, 19 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simulated synovial fluids for in vitro drug and prodrug release testing of depot injectables intended for joint injection
Thing, M., Mertz, Nina, Ågårdh, L., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C., 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 169-176 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies
Azmi, I. D. M., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup
Sun, Y., Chapman, A., Larsen, Susan Weng, Jensen, H., Petersen, Nickolaj J., Goodall, D. M. & Østergaard, Jesper, 5 Jun 2018, In: Analytical Chemistry. 90, 11, p. 6413-6418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin
Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV imaging in pharmaceutical analysis
Østergaard, Jesper, 5 Jan 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 147, p. 140-148Research output: Contribution to journal › Review › Research › peer-review
- Published
Concomitant monitoring of implant formation and drug release of in situ forming poly (lactide-co-glycolide acid) implants in a hydrogel matrix mimicking the subcutis using UV–vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 150, p. 95-106Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 25 Oct 2017, In: Journal of Pharmaceutical and Biomedical Analysis. 145, p. 682-691 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination
Ward, A., Walton, K., Box, K., Østergaard, Jesper, Gillie, L. J., Conway, B. R. & Asare-Addo, K., 15 Sep 2017, In: International Journal of Pharmaceutics. 530, 1-2, p. 139-144 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Automated coating procedures to produce poly(ethylene glycol) brushes in fused-silica capillaries
Poulsen, N. N., Østergaard, Jesper, Petersen, Nickolaj J., Daasbjerg, K., Iruthayaraj, J., Dedinaite, A., Makuska, R. & Jensen, H., Feb 2017, In: Journal of Separation Science. 40, 3, p. 779–788Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of UV Imaging in Formulation Development
Sun, Y. & Østergaard, Jesper, 2017, In: Pharmaceutical Research. 34, 5, p. 929–940 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limits in Size of Taylor Dispersion Analysis: Representation of the Different Hydrodynamic Regimes and Application to the Size-Characterization of Cubosomes
Chamieh, J., Leclercq, L., Martin, M., Slaoui, S., Jensen, H., Østergaard, Jesper & Cottet, H., 2017, In: Analytical Chemistry. 89, 24, p. 13487-13493Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Jensen, S. S., Jensen, H., Goodall, D. M. & Østergaard, Jesper, 30 Nov 2016, In: Journal of Pharmaceutical and Biomedical Analysis. 131, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension
Mertz, Nina, Larsen, Susan Weng, Kristensen, Jesper Langgaard, Østergaard, Jesper & Larsen, C., 27 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3079–3087 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions
Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 6 May 2016, IPC No. A61P 29/ 00 A I, Patent No. WO2016066612, Priority date 28 Oct 2014, Priority No. DK20140070657Research output: Patent
- Published
PRODRUGS OF NAPROXEN AND DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 17 Mar 2016, IPC No. A61K 45/ 06 A I, Patent No. US2016074523, Priority date 28 Apr 2014, Priority No. WO2014EP58530Research output: Patent
- Published
Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery
Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis
Jensen, S. S., Jensen, H., Møller, E. H., Cornett, Claus, Siepmann, F., Siepmann, J. & Østergaard, Jesper, 1 Jan 2016, In: European Journal of Pharmaceutical Sciences. 81, p. 103-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward a New Approach for Diagnosis and Patient Stratification
Poulsen, N. N., Pedersen, M. E., Østergaard, Jesper, Petersen, Nickolaj J., Nielsen, C. T., Heegaard, N. H. H. & Jensen, H., 2016, In: Analytical Chemistry. 88, 18, p. 9056-61 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation
Colombo, S., Brisander, M., Haglöf, J., Sjövall, P., Andersson, P., Østergaard, Jesper & Malmsten, M., 15 Oct 2015, In: International Journal of Pharmaceutics. 494, 1, p. 205-217 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A method for studies on interactions between a gold-based drug and plasma proteins based on capillary electrophoresis with inductively coupled plasma mass spectrometry detection
Nguyen, T. T. T. N., Østergaard, Jesper & Gammelgaard, Bente, 2 Sep 2015, In: Analytical and Bioanalytical Chemistry. 407, 28, p. 8497-8503 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow induced dispersion analysis rapidly quantifies proteins in human plasma samples
Poulsen, N. N., Andersen, N. Z., Østergaard, Jesper, Zhuang, G., Petersen, Nickolaj J. & Jensen, H., 7 Jul 2015, In: The Analyst. 140, 13, p. 4365-69 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of microwave oven heating for prediction of drug-excipient compatibilities and accelerated stability studies
Schou-Pedersen, A. M. V., Østergaard, Jesper, Cornett, Claus & Hansen, S. H., 15 May 2015, In: International Journal of Pharmaceutics. 485, 1-2, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulatory Effect of Human Plasma on the Internal Nanostructure and Size Characteristics of Liquid-Crystalline Nanocarriers
Mat Azmi, I. D. B., Wu, L., Wibroe, P. P., Nilsson, C., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 30 Apr 2015, In: Langmuir. 31, 18, p. 5042–49 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid
Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy
Schou-Pedersen, A. M. V., Cornett, Claus, Nyberg, N., Østergaard, Jesper & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin
Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Microenvironmental pH measurement during sodium naproxenate dissolution in acidic medium by UV/vis imaging
Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. & Lenke, J., 17 Aug 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 100, p. 290-293 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of the esterification of active pharmaceutical ingredients containing carboxylic Acid functionality in polyethylene glycol: formulation implications
Schou-Pedersen, A. M. V., Hansen, S. H., Moesgaard, B. & Østergaard, Jesper, Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2424-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure
Nilsson, C., Østergaard, Jesper, Larsen, Susan Weng, Larsen, C., Urtti, A. & Yaghmur, Anan, 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin diffusion and self-association characterized by real-time UV imaging and Taylor dispersion analysis
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 15 Apr 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 92, p. 203-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of stability constants of tauro- and glyco-conjugated bile salts with the negatively charged sulfobutylether-β-cyclodextrin: comparison of affinity capillary electrophoresis and isothermal titration calorimetry and thermodynamic analysis of the interaction
Holm, R., Østergaard, Jesper, Schönbeck, C., Jensen, H., Shi, W., Peters, G. H. & Westh, P., Apr 2014, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 78, 1-4, p. 185-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing
Østergaard, Jesper, Wu, J., Naelapää, K., Bøtker, Johan Peter, Jensen, H. & Rantanen, Jukka, Apr 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1149-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
Thing, M., Agårdh, L., Larsen, Susan Weng, Rasmussen, R., Pallesen, J., Mertz, N., Kristensen, Jesper Langgaard, Hansen, M., Østergaard, Jesper & Larsen, C. S., 2014, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4021–4029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug formulations based on self-assembled liquid crystalline nanostructures
Yaghmur, Anan, Østergaard, Jesper, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Rappolt, M., 2014, Liposomes, lipid bilayers and model membranes: From basic research to application. Pabst, G., Kucerka, N., Nieh, M-P. & Katsaras, J. (eds.). Boca Raton: CRC Press, p. 341-360Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
UV imaging for in vitro dissolution and release studies: Initial experiences
Østergaard, Jesper, Lenke, J., Jensen, S. S., Sun, Y. & Ye, F., 2014, In: Dissolution Technologies. 21, 4, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis
Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods
Sarnes, A., Østergaard, Jesper, Jensen, S. S., Aaltonen, J., Rantanen, Jukka, Hirvonen, J. & Peltonen, L., 20 Nov 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 511-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis
Zhuang, G., Poulsen, N. N., Petersen, Nickolaj J., Østergaard, Jesper & Jensen, H., 2 Sep 2013, 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. p. 1054-1057 4 p. 6559903Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication
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Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging
Gaunø, M. H., Vilhelmsen, T., Larsen, C. C., Bøtker, Johan Peter, Wittendorff, J., Rantanen, Jukka & Østergaard, Jesper, Sep 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 83, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications
Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, Anan, 7 Aug 2013, In: Biomaterials. 34, 33, p. 8491-8503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat
Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of platinum drug release and liposome stability in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 5 Jun 2013, In: International Journal of Pharmaceutics. 449, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 10 May 2013, IPC No. C07D 487/ 04 A I, Patent No. WO2013064153, Priority date 31 Oct 2011, Priority No. DK20110070591Research output: Patent
- Published
Interaction of Amino Acid and Dipeptide beta-Naphthylamide Derivatives with Hyaluronic Acid and Human Serum Albumin Studied by Capillary Electrophoresis Frontal Analysis
Ye, F., Xie, Y., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, Jan 2013, In: Chromatographia. 76, 1-2, p. 49-57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of supercritical fluid chromatography for testing of PEG adducts in pharmaceuticals
Schou-Pedersen, A. M. V., Østergaard, Jesper, Johansson, M., Dubant, S., Frederiksen, R. B. & Hansen, S. H., 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 256-261Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kvalitetssikring af målrettede nanopartikler til kemoterapi
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Lægemiddelforskning. 2012, p. 50-51Research output: Contribution to journal › Journal article › Communication
- Published
Medicindepot dannes efter injektion i leddet
Larsen, Susan Weng, Thing, M. A., Østergaard, Jesper, Kristensen, Jesper Langgaard, Hansen, M. & Larsen, C. S., 2013, In: Lægemiddelforskning. 2013, p. 38-40Research output: Contribution to journal › Journal article › Research
- Published
Metallomics in drug development: characterization of a liposomal cisplatin drug formulation in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Analytical and Bioanalytical Chemistry. 405, 6, p. 1845-1854Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation
Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physicochemical profiling of drug candidates using capillary-based techniques
Jensen, H., Larsen, Susan Weng, Larsen, C. S. & Østergaard, Jesper, 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging
Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration
Larsen, Susan Weng, Østergaard, Jesper, Yaghmur, Anan, Jensen, H. & Larsen, C., 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Physico-chemical characterization of liposomes and drug substance-liposome interactions in pharmaceutics using capillary electrophoresis and electrokinetic chromatography
Franzen, U. & Østergaard, Jesper, Dec 2012, In: Journal of Chromatography A. 1267, p. 32-44 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning
Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Affinity capillary electrophoresis method for investigation of bile salts complexation with sulfobutyl ether-ß-cyclodextrin
Østergaard, Jesper, Jensen, H. & Holm, R., 2012, In: Journal of Separation Science. 35, 20, p. 2764-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behaviour of HPMC compacts investigated using UV-imaging
Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition
Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In: Langmuir. 28, 5, p. 2881-2889Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem
Nilsson, C., Edwards, K., Eriksson, J., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C. S., Urtti, A. & Yaghmur, Anan, 2012, In: Langmuir. 28, 32, p. 11755-11766Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug release into hydrogel-based subcutaneous surrogates studied by UV imaging
Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 71, p. 27-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties
Jensen, M., Canning, A., Chiha, S., Bouquerel, P., Pedersen, J. T., Østergaard, Jesper, Cuvillier, O., Sasaki, I., Hureau, C. & Faller, P., 2012, In: Chemistry: A European Journal. 18, 16, p. 4836-4839 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis
Ye, F., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 61, p. 176-183Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells
Yang, L., Fawcett, J. P., Østergaard, Jesper, Zhang, H. & Tucker, I. G., 2012, In: Molecular Pharmaceutics. 9, 1, p. 29-36Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
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