Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor

Member of:

    ORCID: 0000-0002-6337-5489

    Publication year:
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    1 - 50 out of 112Page size: 50
    1. 2006
    2. Published

      Allosteric activation of coagulation factor VIIa visualized by hydrogen exchange

      Rand, Kasper Dyrberg, Jørgensen, T., Olsen, Ole, Persson, E., Jensen, O., Stennicke, H. R. & Andersen, M., 2006, In: Journal of Biological Chemistry. 281, 32, p. 23018-24 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1.

      Liew, C. W., Rand, Kasper Dyrberg, Simpson, R. J. Y., Yung, W. W., Mansfield, R. E., Crossley, M., Proetorius-Ibba, M., Nerlov, C., Poulsen, F. M. & Mackay, J. P., 2006, In: Journal of Biological Chemistry. 281, 38, p. 28296-306 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2007

    5. A combined structural dynamics approach identifies a putative switch in factor VIIa employed by tissue factor to initiate blood coagulation

      Olsen, O. H., Rand, Kasper Dyrberg, Østergaard, H. & Persson, E., 2007, In: Protein Science. 16, 4, p. 671-82 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Development of a peptide probe for the occurrence of hydrogen (1H/2H) scrambling upon gas-phase fragmentation

      Rand, Kasper Dyrberg & Jørgensen, T., 2007, In: Analytical Chemistry. 79, 22, p. 8686-93 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2008
    8. Published

      Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor

      Svensson, L. A., Bondensgaard, K., Nørskov-Lauritsen, L., Christensen, L., Becker, P., Andersen, M., Maltesen, M. J., Rand, Kasper Dyrberg, Breinholt, J. & Maltesen, M. J., 2008, In: Journal of Biological Chemistry. 283, 27, p. 19085-94 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Electron capture dissociation proceeds with a low degree of intramolecular migration of peptide amide hydrogens

      Rand, Kasper Dyrberg, Adams, C. M., Zubarev, R. & Jørgensen, T., 2008, In: Journal of the American Chemical Society. 130, 4, p. 1341-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Electron transfer dissociation facilitates the measurement of deuterium incorporation into selectively labeled peptides with single residue resolution

      Zehl, M., Rand, Kasper Dyrberg, Jensen, O. & Jørgensen, T., 2008, In: Journal of the American Chemical Society. 130, 51, p. 17453-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Gas-phase fragmentation of peptides by MALDI in-source decay with limited amide hydrogen (1H/2H) scrambling

      Bache, N., Rand, Kasper Dyrberg, Roepstorff, P. & Jørgensen, T., 2008, In: Analytical Chemistry. 80, 16, p. 6431-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry

      Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. The origins of enhanced activity in factor VIIa analogs and the interplay between key allosteric sites revealed by hydrogen exchange mass spectrometry

      Rand, Kasper Dyrberg, Andersen, M., Olsen, O. H., Jørgensen, T., Ostergaard, H., Jensen, O., Stennicke, H. R. & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 19, p. 13378-87 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 2009

    15. Gas-phase hydrogen/deuterium exchange in a traveling wave ion guide for the examination of protein conformations

      Rand, Kasper Dyrberg, Pringle, S. D., Murphy, J. P., Fadgen, K. E., Brown, J. & Engen, J. R., 2009, In: Analytical Chemistry. 81, 24, p. 10019-28 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry

      Rand, Kasper Dyrberg, Zehl, M., Jensen, O. & Jørgensen, T., 2009, In: Analytical Chemistry. 81, 14, p. 5577-84 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. 2010

    18. Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry

      Hebling, C. M., Morgan, C. R., Stafford, D. W., Jorgenson, J. W., Rand, Kasper Dyrberg & Engen, J. R., 2010, In: Analytical Chemistry. 82, 13, p. 5415-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Conformational dynamics of the Escherichia coli DNA polymerase manager proteins UmuD and UmuD'

      Fang, J., Rand, Kasper Dyrberg, Silva, M. C., Wales, T. E., Engen, J. R. & Beuning, P. J., 2010, In: Journal of Molecular Biology. 398, 1, p. 40-53 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Loss of ammonia during electron-transfer dissociation of deuterated peptides as an inherent gauge of gas-phase hydrogen scrambling

      Rand, Kasper Dyrberg, Zehl, M., Jensen, O. & Jørgensen, T., 2010, In: Analytical Chemistry. 82, 23, p. 9755-62 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. 2011

    22. Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

      Kim, M., Sun, Z. J., Rand, Kasper Dyrberg, Shi, X., Song, L., Cheng, Y., Fahmy, A. F., Majumdar, S., Ofek, G., Yang, Y., Kwong, P. D., Wang, J., Engen, J. R., Wagner, G. & Reinherz, E. L., 2011, In: Nature Structural and Molecular Biology. 18, 11, p. 1235-43 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscs

      Morgan, C. R., Hebling, C. M., Rand, Kasper Dyrberg, Stafford, D. W., Jorgenson, J. W. & Engen, J. R., 2011, In: Molecular and Cellular Proteomics. 10, 9, p. M111.010876

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements

      Rand, Kasper Dyrberg, Pringle, S. D., Morris, M., Engen, J. R. & Brown, J. M., 2011, In: Journal of The American Society for Mass Spectrometry. 22, 10, p. 1784-1793

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. False EX1 signatures caused by sample carryover during HX MS analyses

      Fang, J., Rand, Kasper Dyrberg, Beuning, P. J. & Engen, J. R., 2011, In: International Journal of Mass Spectrometry. 302, 1-3, p. 19-25 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Spatially resolved protein hydrogen exchange measured by matrix-assisted laser desorption ionization in-source decay

      Rand, Kasper Dyrberg, Bache, N., Nedertoft, M. M. & Jørgensen, T., 2011, In: Analytical Chemistry. 83, 23, p. 8859-62 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry

      Rand, Kasper Dyrberg, Lund, F. W., Amon, S. & Jørgensen, Thomas, Apr 2011, In: International Journal of Mass Spectrometry.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2012
    29. Published

      Massespektrometri viser vejen til forbedrede proteinlægemidler

      Song, H. & Rand, Kasper Dyrberg, 2012, In: Lægemiddelforskning. 2012, p. 43-46

      Research output: Contribution to journal › Journal article › Communication

    30. Published

      Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation

      Rand, Kasper Dyrberg, Pringle, S. D., Morris, M. & Brown, J. M., 2012, In: Analytical Chemistry. 84, 4, p. 1931-1940

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2013
    32. Published

      Pinpointing changes in higher-order protein structure by hydrogen/deuterium exchange coupled to electron transfer dissociation mass spectrometry

      Rand, Kasper Dyrberg, 15 Mar 2013, In: International Journal of Mass Spectrometry. 338, p. 2-10 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    33. 2014
    34. Published

      A conformational investigation of propeptide binding to the integral membrane protein γ-glutamyl carboxylase using nanodisc hydrogen exchange mass spectrometry

      Parker, C. H., Morgan, C. R., Rand, Kasper Dyrberg, Engen, J. R., Jorgenson, J. W. & Stafford, D. W., 11 Mar 2014, In: Biochemistry. 53, 9, p. 1511-20 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

      Leurs, U., Lohse, B., Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In: A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

      Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling

      Rand, Kasper Dyrberg, Zehl, M. & Jørgensen, T. J. D., 21 Oct 2014, In: Accounts of Chemical Research. 47, 10, p. 3018-27 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Sites involved in intra- and interdomain allostery associated with the activation of factor VIIa pinpointed by hydrogen-deuterium exchange and electron transfer dissociation mass spectrometry

      Song, H., Olsen, O. H., Persson, E. & Rand, Kasper Dyrberg, 24 Oct 2014, In: The Journal of Biological Chemistry. 289, p. 35388-96 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale

      Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Dec 2014, In: Analytical Chemistry. 86, 23, p. 11868-76 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. 2015
    41. Published

      Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry

      Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    42. Published

      Measuring the binding interfaces of protein complexes by gas-phase hydrogen/deuterium exchange mass spectrometry (gas-phase HDX-MS)

      Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2015.

      Research output: Contribution to conference › Conference abstract for conference › Research

    43. Published

      Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

      Lafleur, J. P., Senkbeil, S., Novotny, J., Nys, G., Bøgelund, N., Rand, Kasper Dyrberg, Foret, F. & Kutter, Jörg P., 2015, In: Lab On a Chip. 15, 10, p. 2162-72 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry

      Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Probing the Conformational and Functional Consequences of Disulfide Bond Engineering in Growth Hormone by Hydrogen-Deuterium Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation

      Seger, S. T., Breinholt, J., Faber, J. H., Andersen, M. D., Wiberg, C., Schjødt, C. B. & Rand, Kasper Dyrberg, 16 Jun 2015, In: Analytical Chemistry. 87, 12, p. 5973-80 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Conformational analysis of large and highly disulfide-stabilized proteins by integrating online electrochemical reduction into an optimized H/D exchange mass spectrometry workflow

      Trabjerg, Esben, Jakobsen, R. U., Mysling, S., Christensen, S., Jørgensen, T. J. D. & Rand, Kasper Dyrberg, 6 Aug 2015, In: Analytical Chemistry. 87, 17, p. 8880–8888 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Formation of covalent di-tyrosine dimers in recombinant α-synuclein

      van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 2016
    49. Published

      A simple sheathless CE-MS interface with a sub-micrometer electrical contact fracture for sensitive analysis of peptide and protein samples

      Nguyen, T. T. T. N., Petersen, Nickolaj J. & Rand, Kasper Dyrberg, 2016, In: Analytica Chimica Acta. 936, p. 157–167 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Analytical Techniques in the Pharmaceutical Sciences

      Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer Publishing Company, p. 253-289 36 p. (Advances in Delivery Science and Technology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    51. Published

      Direct coupling of a flow-flow electromembrane extraction probe to LC-MS

      Fuchs, D., Gabel-Jensen, C., Jensen, H., Rand, Kasper Dyrberg, Pedersen-Bjergaard, Stig, Hansen, S. H. & Petersen, Nickolaj J., 2016, In: Analytica Chimica Acta. 905, p. 93-99 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      The Impact of the ‘Austrian’ Mutation of the Amyloid Precursor Protein Transmembrane Helix is Communicated to the Hinge Region

      Stelzer, W., Scharnagl, C., Leurs, U., Rand, Kasper Dyrberg & Langosch, D., 2016, In: ChemistrySelect. 1, 15, p. 4408-4412 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Conformational destabilization of Immunoglobulin G increases the low pH-binding affinity with the Neonatal Fc Receptor

      Walters, B. T., Jensen, P. F., Larraillet, V., Lin, K., Patapoff, T., Schlothauer, T., Rand, Kasper Dyrberg & Zhang, J., 22 Jan 2016, In: Journal of Biological Chemistry. 291, 4, p. 1817-1825 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Probing the Binding Interfaces of Protein Complexes Using Gas-Phase H/D Exchange Mass Spectrometry

      Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Feb 2016, In: Structure. 24, 2, p. 310-318 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry

      Houde, D., Esmail Nazari, Z., Bou-Assaf, G. M., Weiskopf, A. S. & Rand, Kasper Dyrberg, 9 Feb 2016, In: Journal of the American Society for Mass Spectrometry. 27, 4, p. 669–676 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Gas-phase fragmentation of peptides to increase the spatial resolution of the Hydrogen Exchange Mass Spectrometry experiment

      Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 127-148 22 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    57. Published

      Hydrogen exchange: A sensitive analytical window into protein conformation and dynamics

      Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of protein: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 1-17 17 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    58. Published

      Fully Automated Electro Membrane Extraction Autosampler for LC-MS Systems Allowing Soft Extractions for High-Throughput Applications.

      Fuchs, D., Pedersen-Bjergaard, Stig, Jensen, H., Rand, Kasper Dyrberg, Hansen, S. H. & Petersen, Nickolaj J., 29 May 2016, In: Analytical Chemistry. 88, 13, p. 6797−6804 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Investigating the Role of Artemin Glycosylation

      Danwen, Q., Code, C., Quan, C., Gong, B., Arndt, J., Pepinsky, B., Rand, Kasper Dyrberg & Houde, D., Jun 2016, In: Pharmaceutical Research. 33, 6, p. 1383-1398 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      A novel sensitive sheathless CE-MS device for peptide and protein analysis

      Nguyen, T. T. T. N., Petersen, Nickolaj J. & Rand, Kasper Dyrberg, 8 Jun 2016. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    61. Published

      Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

      Esmail Nazari, Z., van de Weert, Marco, Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, Kasper Dyrberg, 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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