Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor

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    ORCID: 0000-0002-6337-5489

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    1. Published

      Thiol-ene Monolithic Pepsin Microreactor with a 3D-Printed Interface for Efficient UPLC-MS Peptide Mapping Analyses

      Jönsson, A., Svejdal, R. R., Bøgelund, N., Nguyen, T. T. T. N., Flindt, H., Kutter, Jörg P., Rand, Kasper Dyrberg & Lafleur, J. P., 21 Mar 2017, In: Analytical Chemistry. 89, 8, p. 4573-4580 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Circularized and solubility-enhanced MSPs facilitate simple and high-yield production of stable nanodiscs for studies of membrane proteins in solution

      Johansen, Nicolai Tidemand, Tidemand, Frederik Grønbæk, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Pedersen, Martin Cramer & Arleth, Lise, May 2019, In: F E B S Journal. 286, 9, p. 1734-1751

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry

      Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins

      Jensen, P. F., Comamala Grau, G., Trelle, M. B., Madsen, J. B., Jorgensen, T. J. D. & Rand, Kasper Dyrberg, 20 Dec 2016, In: Analytical Chemistry. 88, 24, p. 12479-12488 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Hydrogen exchange: A sensitive analytical window into protein conformation and dynamics

      Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of protein: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 1-17 17 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    6. Published

      Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

      Jensen, P. F., Kadziola, Anders, Comamala, G., Segura, D. R., Anderson, L., Poulsen, Jens-Christian Navarro, Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, Leila & Rand, Kasper Dyrberg, 2019, In: Cell Chemical Biology. 26, 2, p. 191-202.e1-e6 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life

      Jensen, P. F., Schoch, A., Larraillet, V., Hilger, M., Schlothauer, T., Emrich, T. & Rand, Kasper Dyrberg, Mar 2017, In: Molecular and Cellular Proteomics. 16, 3, p. 451-456 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Gas-phase fragmentation of peptides to increase the spatial resolution of the Hydrogen Exchange Mass Spectrometry experiment

      Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 127-148 22 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    9. Published

      The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study

      Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P. C., Bernfur, K., Borchers, C. H., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T. N., Degliesposti, G., Dong, M-Q., Edinger, N., Emanuelsson, C., Gay, M. & 53 others, Gomes-Neto, F., Gozzo, F. C., Gutierrez, C. B., Haupt, C., Heck, A. J. R., Herzog, F., Huang, L., Hoopmann, M. R., Kalisman, N., Klykov, O., Kukačka, Z., Liu, F., MacCoss, M. J., Mechtler, K., Mesika, R., Moritz, R. L., Nagaraj, N., Nesati, V., Neves-Fereira, A. G. C., Ninnis, R., Novák, P., O'Reilly, F. J., Pelzing, M., Petrotchenko, E. V., Piersimoni, L., Plasencia, M., Pukala, T. L., Rand, Kasper Dyrberg, Rappsilber, J., Reichman, D., Sailer, C., Sarnowski, C. P., Scheltema, R. A., Schmidt, C., Schriemer, D. C., Shi, Y., Skehel, J. M., Slavin, M., Sobott, F., Solis-Mezarino, V., Stephanowitz, H., Stengel, F., Stieger, C. E., Trabjerg, Esben, Trnka, M. J., Vilaseca, M., Viner, R., Xiang, Y., Yılmaz, Ş., Zelter, A., Ziemianowicz, D. S., Leitner, A. & Sinz, A., 2 May 2019, In: Analytical Chemistry. 91, 11, p. 6953-6961

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix

      Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, Kasper Dyrberg, Scharnagl, C. & Langosch, D., 27 Feb 2018, In: Biochemistry. 57, 8, p. 1326-1337 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

      Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A. & 16 others, Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 May 2019, In: Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

      Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry

      Houde, D., Esmail Nazari, Z., Bou-Assaf, G. M., Weiskopf, A. S. & Rand, Kasper Dyrberg, 9 Feb 2016, In: Journal of the American Society for Mass Spectrometry. 27, 4, p. 669–676 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Molecular Basis of the Mechanisms Controlling MASTL

      Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry

      Hebling, C. M., Morgan, C. R., Stafford, D. W., Jorgenson, J. W., Rand, Kasper Dyrberg & Engen, J. R., 2010, In: Analytical Chemistry. 82, 13, p. 5415-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.

      Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes

      Guo, R., Comamala, G., Yang, H., Gramlich, M., Du, Y., Wang, T., Zeck, A., Rand, Kasper Dyrberg, Liu, L. & Voglmeir, J., 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 7 p., 741.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

      Grauslund, L. R., Ständer, S., Veggi, D., Andreano, E., Rand, Kasper Dyrberg & Norais, N., 2024, In: Molecular & cellular proteomics : MCP. 23, 3, 100734.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies

      Grauslund, L. R., Calvaresi, V., Pansegrau, W., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Journal of the American Society for Mass Spectrometry. 32, 7, p. 1575–1582

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Direct coupling of a flow-flow electromembrane extraction probe to LC-MS

      Fuchs, D., Gabel-Jensen, C., Jensen, H., Rand, Kasper Dyrberg, Pedersen-Bjergaard, Stig, Hansen, S. H. & Petersen, Nickolaj J., 2016, In: Analytica Chimica Acta. 905, p. 93-99 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Fully Automated Electro Membrane Extraction Autosampler for LC-MS Systems Allowing Soft Extractions for High-Throughput Applications.

      Fuchs, D., Pedersen-Bjergaard, Stig, Jensen, H., Rand, Kasper Dyrberg, Hansen, S. H. & Petersen, Nickolaj J., 29 May 2016, In: Analytical Chemistry. 88, 13, p. 6797−6804 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

      Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. False EX1 signatures caused by sample carryover during HX MS analyses

      Fang, J., Rand, Kasper Dyrberg, Beuning, P. J. & Engen, J. R., 2011, In: International Journal of Mass Spectrometry. 302, 1-3, p. 19-25 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Conformational dynamics of the Escherichia coli DNA polymerase manager proteins UmuD and UmuD'

      Fang, J., Rand, Kasper Dyrberg, Silva, M. C., Wales, T. E., Engen, J. R. & Beuning, P. J., 2010, In: Journal of Molecular Biology. 398, 1, p. 40-53 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

      Esmail Nazari, Z., van de Weert, Marco, Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, Kasper Dyrberg, 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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