Holger Grohganz
Associate Professor
Solid State Pharmaceutics
Universitetsparken 2, 2100 København Ø
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
- Published
Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application
Gabelmann, A., Lehr, C. M. & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 6, 15 p., 1574.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drugs and dosage forms
Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of lysozyme on mannitol polymorphism in freeze-dried and spray-dried formulations depends on the selection of the drying process
Grohganz, Holger, Lee, Y., Rantanen, Jukka & Yang, Mingshi, 15 Apr 2013, In: International Journal of Pharmaceutics. 447, 1-2, p. 224-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlling production process: incorporating analytical methods
Grohganz, Holger & Rantanen, Jukka, 2008, In: Pharma focus Asia. 8, p. 82-83Research output: Contribution to journal › Journal article › Communication
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Towards a robust water content determination of freeze-dried samples by near-infrared spectroscopy
Grohganz, Holger, Gildemyn, D., Skibsted, E., Fink, J. M. & Rantanen, Jukka, 2010, In: Analytica Chimica Acta. 676, p. 34-40Research output: Contribution to journal › Journal article › Research › peer-review
Development and validation of a HPLC method for routine quantification of the decapeptide Cetrorelix in liposome dispersions
Grohganz, Holger, Schläfli, O., Rischer, M. & Brandl, M., 2004, In: Journal of Pharmaceutical and Biomedical Analysis. 34, 5, p. 963-969Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classification of lyophilised mixtures using multivariate analysis of NIR spectra
Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2010, In: European Journal of Pharmaceutics and Biopharmaceutics. 74, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining stability and dissolution rate of amorphous drug formulations
Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid solid-state analysis of freeze-dried protein formulations using NIR and raman spectroscopies
Grohganz, Holger, Gildemyn, D., Skibsted, E., Flink, J. M. & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of various phosphatidylcholines in liposomes by enzymatic assay
Grohganz, Holger, Ziroli, V., Massing, U. & Brandl, M., 2003, In: AAPS PharmSciTech. 4, 4Research output: Contribution to journal › Journal article › Research › peer-review
Development and in vitro evaluation of a liposome based implant formulation for the decapeptide cetrorelix
Grohganz, Holger, Tho, I. & Brandl, M., 2005, In: European Journal of Pharmaceutics and Biopharmaceutics. 59, 3, p. 439-448Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Near-infrared (NIR) spectroscopy – a versatile tool for pharmaceutical research and production
Grohganz, Holger, 2011, In: European Pharmaceutical Review. 16, 2, p. 57-60Research output: Contribution to journal › Journal article › Communication
Adsorption of the decapeptide Cetrorelix depends both on the composition of dissolution medium and the type of solid surface
Grohganz, Holger, Rischer, M. & Brandl, M., 2004, In: European Journal of Pharmaceutical Sciences. 21, 2-3, p. 191-196Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drugs and dosage forms
Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.Research output: Contribution to journal › Review › Research
- Published
Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy
Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, p. 901-907Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coaxial electrospinning of polycaprolactone: A design of experiments approach
Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media
Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of novel excipients for freeze-dried protein formulations
Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation mechanism of coamorphous drug−amino acid mixtures
Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline
Jensen, K. B. T., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation and characterization of spray-dried co-amorphous drug-amino acid salts
Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients
Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230Research output: Contribution to journal › Review › Research
- Published
Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-former selection for co-amorphous drug-amino acid formulations
Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1421411
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
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159
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
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