Dilip Narayanan
Research Consultant
Structural Biology
Jagtvej 162, Building: 30-1-128
2100 København Ø
Biography
Dilip Narayanan started his research career at The Arctic University of Norway where he in 2017 received a PhD degree under Prof. Richard Alan Engh for the Structure based drug design efforts on ATP dependent enzymes (Protein Kinase and Heat Shock Protein 70). In 2016, he moved to copenhagen as a post doc to work with Prof. Anders Bach at University of Copenhagen to implement a FBDD platform at Department of Drug Design and Pharmacology. In 2020, he started working as Assistant Professor with Prof. Michael Gajhede on cryo-EM to apply in the field of Epigenetics. Later in 2021, he moved back to Anders Bach group to develop small-molecule ligands for the tumor necrosis factor alpha (TNF) receptors. From April 2024, he started working as Staff scientist on BioSAXS.
Research interest
Integrates research on projects understanding oxidative stress, redox signaling, inflammation and epigenetics from a societal point of view.
Expertise areas
- Techniques: Structural biology (X-ray and cryo-EM), protein chemistry, fragment-based drug discovery (FBDD), bioassays (TSA, SPR and FP) for ligand-protein interactions, Structure-based drug design (X-ray, molecular modelling).
- Targets: Protein-protein interactions (PPIs), oxidative stress (Keap1), Redox signaling (NADPH oxidase 2), inflammation (TNF receptors) and epigenetics (KDM5B).
Bibliometrics
See Scopus and Google scholar.
ID: 160904351
Most downloads
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247
downloads
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
72
downloads
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
69
downloads
Targeting the Redox Landscape in Cancer Therapy
Research output: Contribution to journal › Review › Research › peer-review
Published