An overview of recent studies on the analysis of pharmaceutical polymorphs
Research output: Contribution to journal › Journal article › Research › peer-review
Pharmaceutical solids are well known to be able to exist in different solid-state forms and there are a wide variety of solid-state analytical techniques available to characterize pharmaceutical solids and solid-state transformations. In this review, the commonly used solid-state analytical techniques, the type of information collected, and advantages and disadvantages of each technique are discussed, with the focus on their application in solid-state characterization and monitoring solid-state transformations, such as amorphization, crystallization, hydrate formation/dehydration and cocrystal formation. The information gathered from recent literature is compiled in various tables to aid the reader to get a quick overall picture about what type of phenomena have recently been studied and which analytical technique(s) have been used.
Original language | English |
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Journal | Journal of Pharmaceutical and Biomedical Analysis |
Volume | 55 |
Issue number | 4 |
Pages (from-to) | 618-44 |
Number of pages | 27 |
DOIs | |
Publication status | Published - 2011 |
Externally published | Yes |
ID: 40340203