Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
Introductory remarks on publicationslist
Publication Statistics
(data until September 2020)
Books 3 Book chapters 17 Int. peer reviewed journal articles 450
Professional journal articles 32
Conference contributions >700
Patents 13
H Index (Google Scholar) 76
Total number of citations (Google Scholar) 20346
- 2016
- Published
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature
Knopp, Matthias Manne, Gannon, N., Porsch, I., Rask, M. B., Olesen, N. E., Langguth, P., Holm, R. & Rades, Thomas, Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2621-2624 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Lipolysis and Synchrotron Small-Angle X-ray Scattering for the Direct Determination of the Precipitation and Solid-State Form of a Poorly Water-Soluble Drug During Digestion of a Lipid-Based Formulation
Khan, J., Hawley, A., Rades, Thomas & Boyd, B. J., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2631-2639 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs
Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
Knopp, Matthias Manne, Chourak, N., Khan, F., Wendelboe, J., Langguth, P., Rades, Thomas & Holm, R., Aug 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 105, p. 106-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin
Beyer, A., Radi, L., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of surfactants on the dissolution behavior of amorphous formulations
Mah, P. T., Peltonen, L., Novakovic, D., Rades, Thomas, Strachan, C. J. & Laaksonen, T., Jun 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 103, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems
Gniado, K., Löbmann, Korbinian, Rades, Thomas & Erxleben, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 20-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development
Knopp, Matthias Manne, Löbmann, Korbinian, Elder, D. P., Rades, Thomas & Holm, R., 1 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances in co-amorphous drug formulations
Dengale, S. J., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unintended and in situ amorphisation of pharmaceuticals
Priemel, P. A., Grohganz, Holger & Rades, Thomas, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 126-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation and characterization of spray-dried co-amorphous drug-amino acid salts
Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poly(Alkyl Cyanoacrylate) nanoparticles for drug delivery and vaccine development
Graf, A., Krauel-Göllner, K. & Rades, Thomas, 19 Apr 2016, Colloids in Drug Delivery. CRC Press, p. 99-136 38 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions
Knopp, Matthias Manne, Nguyen, J. H., Becker, C., Francke, N. M., Jørgensen, E. B., Holm, P., Holm, R., Mu, Huiling, Rades, Thomas & Langguth, P., Apr 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 101, p. 145-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of PVP/VA copolymer composition on drug-polymer solubility
Rask, M. B., Knopp, Matthias Manne, Olesen, N. E., Holm, R. & Rades, Thomas, 31 Mar 2016, In: European Journal of Pharmaceutical Sciences. 85, p. 10-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
- Published
Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions
Knopp, Matthias Manne, Nguyen, J. H., Mu, Huiling, Langguth, P., Rades, Thomas & Holm, R., Mar 2016, In: The A A P S Journal. 18, 2, p. 416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations
Khan, J., Rades, Thomas & Boyd, B., Mar 2016, In: Pharmaceutical Research. 33, 3, p. 548-62 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO
Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical Analysis of a Method to Predict Drug-Polymer Miscibility
Knopp, Matthias Manne, Olesen, N. E., Huang, Y., Holm, R. & Rades, Thomas, 5 Jan 2016, In: Journal of Pharmaceutical Sciences. 105, 1, p. 362–367 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Formation of drug nanocrystals under nanoconfinement afforded by liposomes
Cipolla, D., Wu, H., Salentinig, S., Boyd, B., Rades, Thomas, Vanhecke, D., Petri-Fink, A., Rothin-Rutishauser, B., Eastman, S., Redelmeier, T., Gonda, I. & Chan, H., 2016, In: RSC Advances. 6, 8, p. 6223-6233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation
Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine to Precipitate in an Amorphous-Salt Form during in Vitro Digestion
Khan, J., Rades, Thomas & Boyd, B. J., 2016, In: Molecular Pharmaceutics. 13, 11, p. 3783-3793 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes
Klukkert, M., Wu, J. X., Rantanen, Jukka, Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: European Journal of Pharmaceutical Sciences. 90, p. 85-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-destructive Quality control of tablets and blister packs by UV imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: Pharmazeutische Industrie. 78, 1, p. 108-120 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage
Sovago, I., Wang, W., Qiu, D., Raijada, D. K., Rantanen, Jukka, Grohganz, Holger, Rades, Thomas, Bond, A. D. & Löbmann, Korbinian, 2016, In: Molecules. 21, 4, p. 1-13 13 p., 509.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Peltonen, L. & Strachan, C. J., 1 Dec 2015, In: European Journal of Pharmaceutical Sciences. 80, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis, Formulation, and Adjuvanticity of Monodesmosidic Saponins with Olenanolic Acid, Hederagenin and Gypsogenin Aglycones, and some C-28 Ester Derivatives
Greatrex, B. W., Daines, A. M., Hook, S., Lenz, D. H., McBurney, W., Rades, Thomas & Rendle, P. M., Dec 2015, In: ChemistryOpen. 4, 6, p. 740-755 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 13 Oct 2015, In: AAPS PharmSciTech. p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Image Analytical Approach for Needle-Shaped Crystal Counting and Length Estimation
Wu, J. X., Kucheryavskiy, S. V., Jensen, L. G., Rades, Thomas, Muellertz, A. & Rantanen, Jukka, Oct 2015, In: Crystal Growth & Design. 15, 10, p. 4876-4885 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension
Surwase, S. A., Itkonen, L., Aaltonen, J., Saville, D., Rades, Thomas, Peltonen, L. & Strachan, C. J., Oct 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 96, p. 32-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-arginine
Lenz, E., Jensen, K. B. T., Blaabjerg, L. I., Knop, K., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Kleinebudde, P., Oct 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 96, p. 44–52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility
Knopp, Matthias Manne, Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, Korbinian, Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, Thomas, 8 Sep 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysozyme-magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies
Kanjanakawinkul, W., Medlicott, N. J., Rades, Thomas, Puttipipatkhachorn, S. & Pongjanyakul, T., Sep 2015, In: International Journal of Biological Macromolecules. 80, p. 651-658 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy
Sibik, J., Löbmann, Korbinian, Rades, Thomas & Zeitler, J. A., 3 Aug 2015, In: Molecular Pharmaceutics. 12, 8, p. 3062-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems
Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improvement of dissolution rate of indomethacin by inkjet printing.
Wickström, H., Palo, M., Rijckaert, K., Kolakovic, R., Nyman, J. O., Määttänen, A., Ihalainen, P., Peltonen, J., Genina, Natalja, de Beer, T., Löbmann, Korbinian, Rades, Thomas & Sandler, N., 30 Jul 2015, In: European Journal of Pharmaceutical Sciences. 75, p. 91–100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media
Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Polymer Molecular Weight on Drug-Polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Langguth, P., Holm, R. & Rades, Thomas, 3 Mar 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2905–2912 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of low-frequency Raman spectroscopy and chemometrics for the quantification of crystallinity in amorphous griseofulvin tablets
Mah, P. T., Fraser, S. J., Reish, M. E., Rades, Thomas, Gordon, K. C. & Strachan, C. J., Mar 2015, In: Vibrational Spectroscopy. 77, p. 10-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Löbmann, Korbinian, Holm, R., Langguth, P. & Rades, Thomas, Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems
Kojarunchitt, T., Baldursdottir, S., Dong, Y., Boyd, B. J., Rades, Thomas & Hook, S., Jan 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Ageing Effects of Sonchus oleraceus L. (pūhā) Leaf Extracts on H2O2-Induced Cell Senescence
Ou, Z., Rades, Thomas & McDowell, A., 2015, In: Molecules. 20, 3, p. 4548-64 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying
Craye, G., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., 2015, In: Molecules. 20, 12, p. 21532-48 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system
Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation mechanism of coamorphous drug−amino acid mixtures
Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein
Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 2015, In: Molecules. 20, 10, p. 19571-87 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of polymeric excipients in the stabilization of olanzapine when exposed to aqueous environments
Paisana, M., Wahl, M., Pinto, J., Rades, Thomas (ed.), Grohganz, Holger (ed.) & Löbmann, Korbinian (ed.), 2015, In: Molecules. 20, 12, p. 22634-223282 200649.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subunit Vaccine Delivery: Advances in Delivery Science and Technology
Foged, Camilla, Rades, Thomas, Perrie, Y. & Hook, S., 2015, New York.Research output: Book/Report › Book › Research › peer-review
- 2014
- Published
Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour
Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining stability and dissolution rate of amorphous drug formulations
Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate
Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants
Neumann, S., Burkert, K., Kemp, R., Rades, Thomas, Rod Dunbar, P. & Hook, S., 1 Apr 2014, In: Immunology and Cell Biology. 92, p. 535-542Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of binder in granules produced by means of twin screw granulation
Fonteyne, M., Fussell, A. L., Vercruysse, J., Vervaet, C., Remon, J. P., Strachan, C., Rades, Thomas & De Beer, T., 28 Feb 2014, In: International Journal of Pharmaceutics. 462, 1-2, p. 8-10 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceus L.)
Ou, Z., Schmierer, D. M., Strachan, C. J., Rades, Thomas & McDowell, A., 12 Feb 2014, In: The Journal of pharmacy and pharmacology. 66, 7, p. 998-1008 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical Characterization of Synthetic Phosphatidylinositol Dimannosides and Analogues in Binary Systems with Phosphatidylcholine
Hubert, M., Larsen, D. S., Hayman, C. M., Rades, Thomas & Hook, S., 30 Jan 2014, In: Molecular Pharmaceutics. 11, 3, p. 913-921 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unravelling the relationship between degree of disorder and the dissolution behavior of milled glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Aaltonen, J., Peltonen, L. & Strachan, C. J., 6 Jan 2014, In: Molecular Pharmaceutics. 11, 1, p. 234-242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute oral administration of lauric acid reduces energy intake in healthy male
Feltrin, K. L., Brennan, I. M., Rades, Thomas, Horowitz, M. & Feinle-Bisset, C., 2014, In: e - S P E N Journal. 9, 2, p. 69-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach
Bohr, A., Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 2014, In: Current Pharmaceutical Design. 20, 3, p. 325-48 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical imaging and solid state analysis at compact surfaces using UV imaging
Wu, J., Rehder, S., van der Berg, Franciscus Winfried J, Amigo Rubio, J. M., Carstensen, J. M., Rades, Thomas, Leopold, C. S. & Rantanen, Jukka, 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 527-535 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current advances and future trends in characterizing poorly water-soluble drugs using spectroscopic, imaging and data analytical techniques
Wu, J., van der Berg, Franciscus Winfried J, Rantanen, Jukka, Rades, Thomas & Yang, Mingshi, 2014, In: Current Pharmaceutical Design. 20, 3, p. 436-453 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17Research output: Contribution to journal › Journal article › Communication
- Published
Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline
Jensen, K. B. T., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilized amorphous solid dispersions with small molecule excipients
Löbmann, Korbinian, Jensen, K. B. T., Laitinen, R., Rades, Thomas, Strachan, C. & Grohganz, Holger, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 613-626 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin
Löbmann, Korbinian, Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, Thomas, 2014, In: Pharmaceutics. 6, 3, p. 481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Theoretical Considerations in Developing Amorphous Solid Dispersions
Laitinen, R., Priemel, P. A., Surwase, S., Graeser, K., Strachan, C. J., Grohganz, Holger & Rades, Thomas, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 35-90 56 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2013
- Published
Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy
Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, Thomas & Hook, S., 28 Dec 2013, In: Journal of controlled release : official journal of the Controlled Release Society. 172, 3, p. 894-903 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the types of water in Eudragit RLPO polymer and the kinetics of water loss using FTIR
Pirayavaraporn, C., Rades, Thomas, Gordon, K. C. & Tucker, I. G., 15 Dec 2013, In: International Journal of Pharmaceutics. 458, 1, p. 90-98 9 p.Research output: Contribution to journal › Journal article › Research
- Published
Terahertz pulsed imaging as an advanced characterisation tool for film coatings--a review
Haaser, M., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 5 Dec 2013, In: International Journal of Pharmaceutics. 457, 2, p. 510-20 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures
Priemel, P. A., Laitinen, R., Barthold, S., Grohganz, Holger, Lehto, V., Rades, Thomas & Strachan, C. J., 18 Nov 2013, In: International Journal of Pharmaceutics. 456, 2, p. 301-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement
Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging
Haaser, M., Naelapaa, K., Gordon, K. C., Pepper, M., Rantanen, Jukka, Strachan, C. J., Taday, P. F., Zeitler, J. A. & Rades, Thomas, Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1095-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-shear granulation as a manufacturing method for cocrystal granules
Rehder, S., Christensen, N. P. A., Rantanen, Jukka, Rades, Thomas & Leopold, C. S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 1019-30 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ amorphisation of indomethacin with Eudragit® E during dissolution
Priemel, P. A., Laitinen, R., Grohganz, Holger, Rades, Thomas & Strachan, C. J., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats
Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
in vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations
Scherließ, R., Buske, S., Young, K., Weber, B., Rades, Thomas & Hook, S., 1 Oct 2013, In: Vaccine. 31, 42, p. 4812-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging trends in the stabilization of amorphous drugs
Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization and in vitro permeation study of microemulsions and liquid crystalline systems containing the anticholinesterase alkaloidal extract from Tabernaemontana divaricata
Chaiyana, W., Rades, Thomas & Okonogi, S., 16 Aug 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 201-210 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Studies on the lipase-induced degradation of lipid-based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure
Schwab, M., McGoverin, C. M., Gordon, K. C., Winter, G., Rades, Thomas, Myschik, J. & Strachan, C. J., Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 84, 3, p. 456-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drugs and dosage forms
Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.Research output: Contribution to journal › Review › Research
- Published
Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent developments in oral lipid-based drug delivery
Thomas, N., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 375-382 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues
Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, Thomas & Hook, S., 6 May 2013, In: Molecular Pharmaceutics. 10, 5, p. 1928-39 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38132533
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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306
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
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Published