Holger Grohganz

Holger Grohganz

Associate Professor


  1. 2018
  2. Published

    Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

    Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1-2, p. 243-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

    Wu, W., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 15 Jan 2018, In: International Journal of Pharmaceutics. 535, 1-2, p. 86-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin

    Doreth, M., Löbmann, Korbinian, Priemel, P., Grohganz, Holger, Taylor, R., Holm, R., Lopez de Diego, H. & Rades, Thomas, Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 2018, In: International Journal of Pharmaceutics. 544, 1, p. 172-180 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2017
  8. Published

    Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine

    Kasten, G., Nouri, K., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Nov 2017, In: International Journal of Pharmaceutics. 533, 1, p. 138-144 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

    Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Priemel, P., Strachan, C. J. & Rades, Thomas, 30 Oct 2017, In: International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 150-160 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium

    Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 30 Jun 2017, In: International Journal of Pharmaceutics. 526, 1-2, p. 88-94 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

    Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Influence of preparation pathway on the glass forming ability

    Blaabjerg, L. I., Lindenberg, E., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 21 Apr 2017, In: International Journal of Pharmaceutics. 521, 1-2, p. 232-238

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ

    Doreth, M., Hussein, M. A., Priemel, P. A., Grohganz, Holger, Holm, R., Lopez de Diego, H., Rades, Thomas & Löbmann, Korbinian, 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 343-351 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder

    Walker, G., Römann, P., Poller, B., Löbmann, Korbinian, Grohganz, Holger, Rooney, J. S., Huff, G. S., Smith, G. P. S., Rades, Thomas, Gordon, K. C., Strachan, C. J. & Fraser-Miller, S. J., 2017, In: Molecular Pharmaceutics. 14, 12, p. 4675-4684 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation

    Ruggiero, M. T., Krynski, M., Kissi, E. O., Sibik, J., Markl, D., Tan, N. Y., Arslanov, D., van der Zande, W., Redlich, B., Korter, T. M., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas, Elliott, S. R. & Zeitler, J. A., 2017, In: Physical chemistry chemical physics : PCCP. 19, 44, p. 30039-30047

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2016
  19. Published

    Development of a screening method for co-amorphous formulations of drugs and amino acids

    Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACIN

    Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 13 Oct 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 109, p. 140-148 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica

    Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Sep 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin

    Beyer, A., Radi, L., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Recent advances in co-amorphous drug formulations

    Dengale, S. J., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Unintended and in situ amorphisation of pharmaceuticals

    Priemel, P. A., Grohganz, Holger & Rades, Thomas, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 126-32 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

    Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO

    Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling

    Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1421411