Kasper Dyrberg Rand
Professor
- 2024
- Published
Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)
Grauslund, L. R., Ständer, S., Veggi, D., Andreano, E., Rand, Kasper Dyrberg & Norais, N., 2024, In: Molecular & cellular proteomics : MCP. 23, 3, 100734.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties
Code, C., Qiu, D., Solov'yov, I. A., Lee, J., Shin, H., Roland, C., Sagui, C., Houde, D., Rand, Kasper Dyrberg & Jørgensen, T. J. D., 2023, In: Journal of the American Chemical Society. 145, 44, p. 23925-23938Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS
Lambert, Thomas Ole Tandrup, Gramlich, M., Stutzke, L., Smith, L., Deng, D., Kaiser, P. D., Rothbauer, U., Benesch, J. L. P., Wagner, C., Koenig, M., Pompach, P., Novak, P., Zeck, A. & Rand, Kasper Dyrberg, 2023, In: Journal of the American Society for Mass Spectrometry. 34, 11, p. 2556–2566Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction
Sheff, J., Kelly, J., Foss, M., Brunette, E., Kemmerich, K., van Faassen, H., Raphael, S., Hussack, G., Comamala, G., Rand, Kasper Dyrberg & Stanimirovic, D. B., 2023, In: Journal of Biochemistry. 173, 2, p. 95-105Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.
Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT
Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dopamine transporter antiports potassium to increase the uptake of dopamine
Schmidt, S. G., Malle, M. G., Nielsen, A. K., Bohr, S. S., Pugh, Ciara Frances, Nielsen, Jeppe Cederholm, Poulsen, I. H., Rand, Kasper Dyrberg, Hatzakis, Nikos & Loland, Claus Juul, 2022, In: Nature Communications. 13, 1, 12 p., 2446.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments
Calvaresi, V., Truelsen, L. T., Larsen, S. B., Petersen, N. H. T., Kirkegaard, T. & Rand, Kasper Dyrberg, 2021, In: Communications Biology . 4, 1369.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope Mapping of Polyclonal Antibodies by Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)
Ständer, S., Grauslund, L. R., Scarselli, M., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 34, p. 11669–11678Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies
Grauslund, L. R., Calvaresi, V., Pansegrau, W., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Journal of the American Society for Mass Spectrometry. 32, 7, p. 1575–1582Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples
Calvaresi, V., Redsted, A., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 33, p. 11406–11414Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins
Comamala, G., Krogh, C. C., Nielsen, V. S., Kutter, Jörg P., Voglmeir, J. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 49, p. 16330–16340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry
Merkle, P. S., Trabjerg, Esben, Hongjian, S., Ferber, M., Cuendet, M. A., Jorgensen, T. J. D., Luescher, I., Irving, M., Zoete, V., Michielin, O. & Rand, Kasper Dyrberg, 2021, In: Biochemistry. 60, 11, p. 859-872Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Revealing the dynamic allosteric changes required for formation of the cysteine synthase complex by hydrogen-deuterium exchange mass spectrometry
Rosa, B., Dickinson, E. R., Marchetti, M., Campanini, B., Pioselli, B., Bettati, S. & Rand, Kasper Dyrberg, 2021, In: Molecular and Cellular Proteomics. 20, 12 p., 100098.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor
Comamala, G., Wagner, C., de la Torre, P. S., Jakobsen, R. U., Hilger, M., Brouwer, H. & Rand, Kasper Dyrberg, 8 Jun 2020, In: Analytica Chimica Acta. 1115, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An intact C-terminal end of albumin is required for its long half-life in humans
Nilsen, J., Trabjerg, Esben, Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., 20 Apr 2020, In: Communications Biology. 3, 1, 11 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines
Castelli, R., Scalvini, L., Vacondio, F., Lodola, A., Anselmi, M., Vezzosi, S., Carmi, C., Bassi, M., Ferlenghi, F., Rivara, S., Möller, I. R., Rand, K. D., Daglian, J., Wei, D., Dotsey, E. Y., Ahmed, F., Jung, K-M., Stella, N., Singh, S., Mor, M. & 1 others, , 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1261-1280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis
Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, Kasper Dyrberg & Teilum, Kaare, 2020, In: PeerJ. 8, 17 p., e9408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deglycosylation by the Acidic Glycosidase PNGase H+ Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry
Comamala, G., Madsen, J. B., Voglmeir, J., Du, Y., Jensen, P. F., Østerlund, E. C., Trelle, M. B. & Rand, Kasper Dyrberg, 2020, In: Journal of the American Society for Mass Spectrometry. 31, 11, p. 2305-2312Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes
Guo, R., Comamala, G., Yang, H., Gramlich, M., Du, Y., Wang, T., Zeck, A., Rand, Kasper Dyrberg, Liu, L. & Voglmeir, J., 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 7 p., 741.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid
Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Basis of the Mechanisms Controlling MASTL
Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS
Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thiol-ene microfluidic chip for fast on-chip sample clean-up, separation and ESI mass spectrometry of peptides and proteins
Svejdal, R. R., Sticker, Drago, Sønderby, C., Kutter, Jörg P. & Rand, Kasper Dyrberg, 2020, In: Analytica Chimica Acta. 1140, p. 168-177 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
An intact C-terminal end of albumin is required for long serum half-life
Nilsen, J., Trabjerg, E., Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., Dec 2019, p. 19. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
ID: 34783804
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
237
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The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study
Research output: Contribution to journal › Journal article › Research › peer-review
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228
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
Published